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1.
Sci Total Environ ; 802: 149928, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-34464806

RESUMO

Climate change in recent decades led to the remarkable expansions for most lakes in endorheic basins of the Tibetan Plateau (TP). Enlarged lake inundation areas may pose adverse effects and potential threats on the local human living environment, especially for high-risk villages adjacent to rapidly expanding lakes. Taking a rapidly expanding lake, Angzi Co in the central TP as a study case, we investigated the flooding risk of lake growth on the local living environment and proposed an optimized solution of village relocation selection on the basis of satellite and unmanned aerial vehicle (UAV) remote sensing. The detection of spatiotemporal variations of Angzi Co using optical and altimetric satellite observations revealed a significant area and water level increase by 81.28 km2 and 5.78 m, respectively, from 2000 to 2020. We also assessed the vertical accuracy of multi-source digital elevation model (DEM) products using Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2) altimetry data and further examined the flooding risk and potential influences of lake expansion on adjacent settlements (Guozha Village). Results indicated that UAV-DEM achieves excellent advantages in depicting details of lake shoreline variations and simulating potential submergence regions, followed by Advanced Land Observing Satellite World 3D DEM (AW3D DEM). Moreover, assuming that Angzi Co maintains the water level at a growth rate of 0.29 m/a (the average change rate during 2000-2020), the village will be submerged in approximate 10 years based on our assessment. Furthermore, we designed an optimal relocation site southwest of Guozha Village and approximately 3 km away based on the GIS-MVDA method and field investigations. An initial remote sensing-based approach for assessing the flooding risk from dramatic lake expansions in the TP and optimizing the village relocation site was proposed in this study to provide an essential scientific reference for formulating risk mitigation solutions under future climate change scenarios.


Assuntos
Lagos , Tecnologia de Sensoriamento Remoto , Mudança Climática , Inundações , Humanos , Tibet
2.
Oncol Rep ; 47(2)2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34850964

RESUMO

Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the western blotting data in Figs. 3 and 6 were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused. [the original article was published in Oncology Reports 34: 1003­1010, 2015; DOI: 10.3892/or.2015.4030].

3.
Sci Total Environ ; 806(Pt 4): 150767, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-34619199

RESUMO

Atmospheric transport is an important pathway through which microplastics (MPs) are widely exchanged between marine and terrestrial environments. However, the impacts of frequent extreme weather events, such as typhoons, on atmospheric MPs is poorly understood. To address this issue, we collected suspended atmospheric MPs (SAMPs) and rainfall samples in the South China Sea during Typhoon Sinlaku (2020). Our results revealed a higher abundance of suspended MPs (1.05 ± 0.55 n/100 m3) during the typhoon than in the pre-typhoon period (0.59 ± 0.48 n/100 m3). Nine polymer types were identified by micro-FTIR, among which the dominant were polyethylene terephthalate (PET, 62.82%) and polypropylene (PP, 19.23%). Moreover, rainfall appeared more inclined to remove larger sizes, more colors and more polymer types of MPs from the atmosphere. The trajectory source-receptor plot indicated that the typhoon significantly changed the pathway of MP transport in the atmosphere, including the direction and distance. To our knowledge, this is the first study to elucidate the impact of typhoons on atmospheric MP transportation. Our results indicate that airborne MPs may pose unexpected ecological risks to marine and coastal ecosystems due to their increased abundance from more distant sources, resulting from typhoon events.

4.
Oncol Rep ; 47(2)2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34841439

RESUMO

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that various data featured in several of the figures were strikingly similar to data appearing in different form in other articles by different authors. An independent enquiry was launched by the Editorial Office, which revealed that cell migration assay data featured in Fig. 5A and C of the above article had been included in another article written by different authors submitted for publication some 12 months previously. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused. [the original article was published in Oncology Reports 32: 2501-2510, 2014; DOI: 10.3892/or.2014.3503].

5.
Sci Total Environ ; 804: 150138, 2022 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-34517308

RESUMO

Microplastic (MP) fibers are present in all environmental media, yet little is known about their distribution, sources, and transport in the water column of marginal seas. In this study, we conducted an intensive sampling campaign in the marginal sea water column off southeast China, which is an area that is greatly influenced by high MP emissions. We found that hydrological effects largely regulated the spatial variations of MP fiber distribution and that MP fibers likely were not entering the South China Sea through terrestrial input from southeast China during the summer monsoon. Polyethylene terephthalate (PET) fibers were pervasive in the surface water (SW) (89.47%), subsurface chlorophyll maximum layer (SCML) (92.65%), and bottom water (BW) (94.29%) of the water column during the sampling period. Approximately 32% of MP fibers in the samples were smaller than 330 µm. The abundance of MP fibers in SW was significantly lower than that in the SCML and BW. Based on this observation, we estimated the inventory of MP fibers in the SW, SCML, and BW of the sampling area to be 1.377-1.378, 2.820-2.825, and 2.627-2.629 metric tons, respectively. These results improved our understanding of the source-to-sink process of MP fiber contamination in the water column of marginal seas.


Assuntos
Microplásticos , Poluentes Químicos da Água , China , Monitoramento Ambiental , Plásticos , Prevalência , Água do Mar , Poluentes Químicos da Água/análise
6.
Neural Regen Res ; 17(3): 632-642, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34380904

RESUMO

Icariin (ICA) has a significant capacity to protect against depression and hippocampal injury, but it cannot effectively cross the blood-brain barrier and accumulate in the brain. Therefore, the mechanism by which ICA protects against hippocampal injury in depression remains unclear. In this study, we performed proteomics analysis of cerebrospinal fluid to investigate the mechanism by which ICA prevents dysfunctional hippocampal neurogenesis in depression. A rat model of depression was established through exposure to chronic unpredictable mild stress for 6 weeks, after which 120 mg/kg ICA was administered subcutaneously every day. The results showed that ICA alleviated depressive symptoms, learning and memory dysfunction, dysfunctional neurogenesis, and neuronal loss in the dentate gyrus of rats with depression. Neural stem cells from rat embryonic hippocampi were cultured in media containing 20% cerebrospinal fluid from each group of rats and then treated with 100 µM corticosterone. The addition of cerebrospinal fluid from rats treated with ICA largely prevented the corticosterone-mediated inhibition of neuronal proliferation and differentiation. Fifty-two differentially expressed proteins regulated by chronic unpredictable mild stress and ICA were identified through proteomics analysis of cerebrospinal fluid. These proteins were mainly involved in the ribosome, PI3K-Akt signaling, and interleukin-17 signaling pathways. Parallel reaction monitoring mass spectrometry showed that Rps4x, Rps12, Rps14, Rps19, Hsp90b1, and Hsp90aa1 were up-regulated by chronic unpredictable mild stress and down-regulated by ICA. In contrast, HtrA1 was down-regulated by chronic unpredictable mild stress and up-regulated by ICA. These findings suggest that ICA can prevent depression and dysfunctional hippocampal neurogenesis through regulating the expression of certain proteins found in the cerebrospinal fluid. The study was approved by the Experimental Animal Ethics Committee of Guangzhou University of Chinese Medicine of China in March 2017.

7.
J Ethnopharmacol ; 283: 114749, 2022 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-34666140

RESUMO

ETHNOPHARMACOLOGICAL RELEVANCE: Baicalin (BI) is an important biologically active flavonoid isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the common drug of dysentery. As the main flavonoid compound, there is a distribution tendency of baicalin to the intestinal tract and it has a protective effect on the gastrointestinal tract. AIM OF THE REVIEW: This review aims to compile up-to-date and comprehensive information on the efficacy of baicalin in vitro and in vivo, about treating inflammatory bowel disease. Relevant information on the therapeutic potential of baicalin against inflammatory bowel disease was collected from the Web of Science, Pubmed and so on. Additionally, a few books and magazines were also consulted to get the important information. RESULTS: The mechanisms of baicalin against inflammatory bowel disease mainly include anti-inflammation, antioxidant, immune regulation, maintenance of intestinal barrier, maintenance of intestinal flora balance. Also, BI can relieve parts of extraintestinal manifestations (EIMs), and prevent colorectal cancer. CONCLUSION: Baicalin determined the promising therapeutic prospects as potential supplementary medicines for the treatment of IBD.

8.
Sci Total Environ ; 805: 150243, 2022 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-34534870

RESUMO

Marine microplastic (MP) pollution is a global environmental problem that has received attention from scientific researchers and the public for the past several decades. However, without a suitably large-volume sampling method, the presence of MPs in subsurface water (< 5 m) is poorly understood. Here, MP content in subsurface water was determined using a pump-underway ship intake system along the cross-oceanic transect from the Pearl River Estuary to the Indian Ocean. The study regions have always been considered as one of the major MPs hotspots in the global oceans and still lack of study. Generally, MP abundance ranged between 0 and 4.97 items m-3, with an overall mean value of 0.40 ± 0.62 items m-3. A total of 679 MP particles were identified using µ-FT-IR. These collections identified polyethylene (PE), polypropylene (PP), and polyester (PET) as the major polymers represented (73.14-88.81%). The presence of MPs in coastal regions was significantly higher than that in the open ocean, revealing the contribution of land-based sources to marine MPs and the ocean dynamics. Therefore, an effective and feasible way to retard the penetration of MPs into the marine environment is to exhibit controls at the source. No significant correlation was found between the MP abundance and the physical and chemical properties of water. The results of the analysis of similarities (ANOSIM) and non-metric multidimensional scaling (NMDS) also showed that MP communities in different environments were significantly greater than the differences in different sites within the same environment. These findings of this study provide reliable information on MP distribution and characterization in cross-oceanic region of South China Sea and Eastern Indian Ocean, which will help to improve our understanding about the fate of MPs in the ocean.


Assuntos
Microplásticos , Poluentes Químicos da Água , China , Monitoramento Ambiental , Oceano Índico , Plásticos , Espectroscopia de Infravermelho com Transformada de Fourier , Água , Poluentes Químicos da Água/análise
9.
Mol Biol Rep ; 2021 Nov 02.
Artigo em Inglês | MEDLINE | ID: mdl-34727288

RESUMO

BACKGROUND: The mitogenomic heteroplasmy is the presence of multiple haplotypes in the mitochondria, which could cause genetic diseases and is also associated with many critical biological functions. The topmouth culter (Culter alburnus Basilewsky, 1855) is one of the most important freshwater fish in the family of Cyprinidae in China. At present, there are no reports on the topmouth culter's mtDNA heteroplasmy and the existence of which is not known. METHODS AND RESULTS: This study aimed to analyze the mitogenomic heteroplasmy in the topmouth culter by the next-generation sequencing of the fins' total DNA. The results confirmed the existence of the heteroplasmy and indicated the presence of the extensive heteroplasmy in the topmouth culter's mitogenome. There were 38 heteroplasmic variations in the protein-coding genes from the three specimens, with 33 non-synonymous substitutions accounting for 86.84% and five synonymous substitutions accounting for 13.16%. Among them, the ND6 had the most heteroplasmic variations but only one synonymous substitution. After removing the putative nuclear mitochondrial DNA fragments, the ratio of primary haplotype in the three specimens was 43.89%, 74.72%, and 32.76%, respectively. The three specimens contained 21, 7, and 21 haplotypes of the mitogenomes, respectively. Due to the extensive heteroplasmy, we reconstructed the phylogenetic tree of the topmouth culter using the RY-coding method, which improved the performance of the phylogenetic tree to some extent. CONCLUSIONS: This study reported the mitogenomic heteroplasmy in the topmouth culter and enhanced the knowledge regarding the mitogenomic heteroplasmy in phylogenetic studies. As the topmouth culter is a commercial species, the mitogenomic heteroplasmy is crucial for the fisheries management of the topmouth culter.

10.
BMC Plant Biol ; 21(1): 511, 2021 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-34732134

RESUMO

BACKGROUND: The walnut shell, which is composed of a large number of sclereids originating from the lignified parenchyma of the endocarp, plays an important role in fruit development and during harvesting and storage. The physical and chemical properties of walnut shells are closely related to the lignin content. Laccase is the key enzyme responsible for lignin biosynthesis by the polymerization of monolignols and plays crucial roles in secondary cell wall formation in plants. In this study, we screened and identified laccase family genes from the walnut genome and investigated the expression of laccase during endocarp lignification in walnut. RESULTS: A total of 37 laccase genes were screened from the walnut genome and distributed on nine chromosomes and classified into 6 subfamilies, among which subfamily IV showed distinct expansion. We observed that endocarp lignification started 44 days after flowering (DAF), and at later periods, the lignin content increased rapidly, with growth peaks at 44-50 DAF and 100-115 DAF. The lignification of the endocarp proceeded from the outside to the inside, as demonstrated by section staining in combination with endocarp staining. Furthermore, the changes in the expression of laccase family genes in the endocarp at different developmental stages were studied, and JrLACs showed different expression trends. The expression of nine genes showed significant increase after 44 DAF, and among these, JrLAC12-1, JrLAC12-2 and JrLAC16 showed a significant change in expression at the lignification stage. A study of the expression of JrLACs in different tissues and at various endocarp developmental stages revealed, that most JrLACs were expressed at low levels in mature tissues and at high levels in young tissues, in particular, JrLAC12-1 showed high expression in the young stems. A significant positive correlation was found between the expression of JrLAC12-1 and the variation in the lignin content in the endocarp. CONCLUSION: Laccase genes play an important role in the lignification of the walnut endocarp, and JrLACs play different roles during fruit development. This study shows that JrLAC12-1 may play a key role in the lignification of endocarp.

11.
Int J Oncol ; 59(6)2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34726253

RESUMO

Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the flow cytometric data in Fig. 3A and western blotting data featured in Figs. 3C and 7 were strikingly similar to data appearing in different form in other articles that shared some of the same authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to International Journal of Oncology, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused. [the original article was published in International Journal of Oncology 45: 1537­1546, 2014; DOI: 10.3892/ijo.2014.2577].

12.
Artigo em Inglês | MEDLINE | ID: mdl-34764027

RESUMO

Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in both immunocompetent and immunocompromised patients. CMV is a ubiquitous Herpesviridae virus with a wide spectrum of pathologies in humans. Immunocompetent patients generally develop a benign, self-limited mononucleosis-like syndrome, whereas gastrointestinal tissue-invasive disease is more frequently seen in immunocompromised. The clinical manifestations of CMV colitis or proctitis are demarcated by bloody diarrhea, ulcerations, ulcero-infiltrative changes, and pseudomembranous formation on colonoscopy. Gastrointestinal CMV infections complicated with deep rectal ulcer and fistula formation are rare in patients with systemic lupus erythematosus. Ganciclovir is also the gold standard therapy for CMV colitis or proctitis.

13.
Neurophysiol Clin ; 2021 Nov 05.
Artigo em Inglês | MEDLINE | ID: mdl-34750039

RESUMO

OBJECTIVES: -Mismatch negativity (MMN) has been demonstrated as a potential biomarker for pre-attentive processing and prognosis in patients with psychosis. However, previous studies mainly evaluated the reliability of MMN across only two repeated sessions, which is inadequate to draw a convincing conclusion. The current study aimed to assess multi-session test-retest reliability in duration-related MMN (dMMN) and frequency-related MMN (fMMN). METHODS: -We recorded four repeated sessions of electroencephalography (EEG) from 16 healthy participants in an oddball task. MMNs were extracted and their reliability was evaluated by intra-class coefficient (ICC). We also analyzed the correlation between fMMN and dMMN. RESULTS: -Both dMMN and fMMN amplitudes exhibited good test-retest reliability, and fMMN had better reliability (average ICC = 0.7279) than dMMN (average ICC = 0.6974). Moreover, dMMN and fMMN showed more than moderate linear correlation in amplitudes (r = 0.598, CI: [0.100, 0.857]). CONCLUSION: -Both the duration- and frequency-related MMN amplitudes were highly reliable across four-session experiments. These results provide further evidence for the potential utility of MMNs as biomarkers in research into brain function, and prognosis in psychotic illness.

14.
J Hazard Mater ; : 127780, 2021 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-34801297

RESUMO

The redox process of electron shuttles like cysteine on iron minerals under aerobic conditions may largely determine the fate of arsenic (As) in soils, while the interfacial processes and underlying mechanisms are barely explored. This work systematically investigates the interfacial oxidation processes of As(III) on goethite induced by cysteine. Results show that the addition of cysteine significantly enhances the oxidation efficiency (~ 40%) of As(III) (C0: 10 mg/L) by goethite at pH 7 under aerobic conditions, which is 19.5 times of that without cysteine. cysteine induces Fe(III) reduction on the surface of goethite, and the generation absorbed Fe(II) species play an important role in As(III) oxidation. In particular, the further complexation of Fe(II) with cysteine is thermodynamically favorable for electron transfer, leading to an enhanced As(III) oxidation efficiency. The oxidation efficiency of As(III) in the goethite/cysteine system increases by increasing cysteine concentration and decreases by elevating pH conditions. In addition, evidence indicates that •O2- radicals account for approximately 80% of total oxidized As(III). Meanwhile, only 16% of As(III) oxidation can be attributed to the formed •OH radicals. This work provides new insight into the role of organic electron shuttling compounds in determining As cycling in soils.

15.
Molecules ; 26(21)2021 Nov 08.
Artigo em Inglês | MEDLINE | ID: mdl-34771158

RESUMO

Catalytic asymmetric [2 + 4] cycloadditions of 3-vinylindoles with ortho-quinone methides and their precursors were carried out in the presence of chiral phosphoric acid to afford a series of indole-containing chroman derivatives with structural diversity in overall high yields (up to 98%), good diastereoselectivities (up to 93:7 dr) and moderate to excellent enantioselectivities (up to 98% ee). This approach not only enriches the chemistry of catalytic asymmetric cycloadditions involving 3-vinylindoles but is also useful for synthesizing chiral chroman derivatives.

16.
J Orthop Surg Res ; 16(1): 668, 2021 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-34774063

RESUMO

BACKGROUND: It is challenging to determine the orthogonality of radiographs in daily clinical practice. The purpose of this study was to show the usefulness of an additional foot ring which might determine the orthogonality of postoperative radiographs for the parameter measurement of hexapod external fixator. METHODS: We retrospectively analyzed 81 consecutive trauma patients with tibial shaft fractures treated by the hexapod external fixator at our institution from September 2014 to July 2019. Starting in March 2016, the postoperative radiographs for parameter measurement were obtained under the control of an additional foot ring. The final data consisted of 47 patients in traditional radiographs (Group I) and 34 patients under the control of foot ring during the radiographic process (Group II). The demographic data, original postoperative deformities, residual deformities after final correction, number of repeated radiographs after the first postoperative radiographs, time to the satisfactory reduction achieved, and external fixation time in all patients were documented and analyzed. The Johner-Wruhs criteria were used for the final clinical outcomes evaluation at the last clinical visit. RESULTS: Satisfactory reduction and bone union were achieved in all patients. There were no statistical significances between the two groups in the demographic data, original postoperative deformities, residual deformities after final correction, external fixation time, and the final clinical outcomes (P > 0.05). The mean number of repeated radiographs after the first radiographs (1.4 times) and mean time to the satisfactory reduction achieved (3.3 days) in patients with an additional foot ring used were all less than those without foot ring (2.4 times, 5.3 days) (P < 0.05). CONCLUSIONS: The additional foot ring is a practical device to ensure the orthogonality of postoperative radiographs for the hexapod external fixator parameter measurement. Radiation exposure, duration of deformity correction, and cost for patients might be reduced due to the less repeated radiographs with the wrong position.

17.
Artigo em Inglês | MEDLINE | ID: mdl-34792614

RESUMO

PURPOSE: The optimal surgical procedure, whether total gastrectomy (TG) or proximal gastrectomy (PG), for Siewert type II/III adenocarcinoma of esophagogastric junction (AEG) has not been standardised, primarily because the optimal extent of lymph node (LN) dissection for AEG based on the metastatic rate of perigastric LNs remains under debate. The aim of this study was to investigate the metastatic incidence and prognostic significance of lower perigastric lymph nodes (LPLN), including No.4d, 5, 6 and 12a LN stations, in Siewert type II/III AEG. METHODS: A total of 701 patients with Siewert type II/III AEG who received transabdominal open gastrectomy (425 patients with TG and 276 patients with PG) from 2010 to 2015 in West China Hospital were retrospectively included. Based on the clinicopathological information of TG patients, the risk factors of LPLN-positive patients were evaluated, and the metastatic incidence as well as the therapeutic value (TV) index of each LN station was assessed. Moreover, the 5-year overall survival (OS) rates between LPLN-positive and LPLN-negative groups were compared in TG patients, and the postoperative survival difference between TG and PG patients was also compared, using propensity score matching (PSM) method. RESULTS: Tumour size (≥ 5 cm, OR = 1.481, p = 0.002) and pT stage (pT4, OR = 2.755, p = 0.024) were significant risk factors for patients with LPLN metastasis. For patients with tumour size more than 5 cm or pT4 stage, the metastatic rates of LPLN for Siewert type II, III and II/III AEG were 31.67%, 34.69% and 33.03%, whereas the TV indexes of LPLN for them were 5.76, 5.62 and 5.38, respectively. LPLN was a significant independent prognostic factor (HR = 1.422, p = 0.028), and positive LPLN was related to worse prognosis (p < 0.05). For patients with tumour size more than 5 cm or pT4 stage, TG patients were illustrated to have a better prognosis than PG patients, with 5-year OS rates of 58.9% vs 38.2% for Siewert type II AEG (χ2 = 4.159, p = 0.041), 68.9% vs 50.2% for Siewert type III AEG (χ2 = 5.630, p = 0.018) and 65.1% vs 40.3% for Siewert type II/III AEG (χ2 = 12.604, p < 0.001), respectively. CONCLUSIONS: LPLN metastasis is a poor prognostic factor for patients with Siewert II/III AEG. LPLN dissection may improve the long-term survival of patients with tumour size more than 5 cm or pT4 stage, and TG might be more suitable for this kind of cancer.

18.
Mitochondrial DNA B Resour ; 6(12): 3396-3397, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34790873

RESUMO

This study determined the complete mitochondrial genome of Formosania galericula (Cypriniformes: Gastromyzontidae) from Zhejiang, China, for the first time. The complete mitochondrial genome of F. galericula was sequenced to be 16,555 bp in length. The genome contained 13 protein-coding genes, 22 transfer RNAs, two ribosomal RNAs, two central non-coding regions (the control region and the origin of light strand replication), identical to most other vertebrates. Phylogenetic analysis highly supported that F. galericula was close to Crossostoma lacustre and the genus Vanmanenia fish. However, F. galericula was not firstly clustered with Formosania chenyiyui but after the genus Vanmanenia fish. These data would explain the evolutionary mechanisms and biogeography of the family Gastromyzontidae and is helpful for the conservation of genetics and stock evaluation for F. galericula.

19.
Adv Mater ; : e2107304, 2021 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-34796569

RESUMO

Optoelectronic skin is acknowledged as the world current cutting-edge technology in the fields of wearable healthcare monitoring, soft robotics, artificial retinas, and so on. However, the difficulty in preparing stretchable photosensitive polymers and the high-crystallization nature of most reported photosensitive materials (such as perovskites) severely restrict the development of skin-like optoelectronic devices. Herein, a surface energy-induced self-assembly methodology is proposed to form easily transferrable and flexible perovskite quantum dot (PQD) films with a worm-like morphology. Furthermore, intrinsically stretchable phototransistors (ISTPTs) are fabricated based on an stretchable photosensitive layer heterojunction consisting of the worm-like PQD films and hybrid polymer semiconductors. The obtained ISTPTs display highly sensitive response to high-energy photons of X-ray (with a detection limit of 79 nGy s-1 , that is 560 times lower than commercial medical chest X-ray diagnosis) and ultraviolet (with photosensitivity of 5 × 106 and detectable light intensity of 50 nW cm-2 among the highest performance of reported photodetectors). In addition, these ISTPTs demonstrate desirable e-skin characteristics with high strain tolerance, high sensing specificity, high optical transparency, and desirable skin conformability. The surface energy-induced self-assembly methodology for the preparation of ISTPTs is a critical demonstration to enable low-cost and high-performance optoelectronic skins. This article is protected by copyright. All rights reserved.

20.
BMC Cancer ; 21(1): 1193, 2021 Nov 10.
Artigo em Inglês | MEDLINE | ID: mdl-34758772

RESUMO

BACKGROUND: The relationship between the type of anesthesia and the survival outcomes of gastric cancer patients is uncertain. This study compared the overall outcome of gastric cancer patients after surgery with total intravenous anesthesia (TIVA) or inhalation anesthesia (IHA). METHODS: Clinicopathological variables of gastric cancer patients were retrieved from the database of the Surgical Gastric Cancer Patient Registry in West China Hospital, Sichuan University. Patients were grouped according to whether they received TIVA or IHA during the operation. Propensity score (PS) matching was used to balance the baseline variables, and survival outcomes were compared between these two groups. In addition, studies comparing survival outcomes between TIVA and IHA used for gastric cancer surgery and published before April 20th, 2020, were identified, and their data were pooled. RESULTS: A total of 2827 patients who underwent surgical treatment from Jan 2009 to Dec 2016 were included. There were 323 patients in the TIVA group and 645 patients in the IHA group, with 1:2 PS matching. There was no significant difference in overall survival outcomes between the TIVA and IHA groups before matching the cohort (p = 0.566) or after matching the cohort (p = 0.679) by log-rank tests. In the Cox hazard regression model, there was no significant difference between the TIVA and IHA groups before (HR: 1.054, 95% CI: 0.881-1.262, p = 0.566) or after (HR: 0.957, 95% CI: 0.779-1.177, p = 0.679) PS matching. The meta-analysis of survival outcomes between the TIVA and IHA groups found critical statistical value in the before PS matching cohort (HR 0.74, 95% CI: 0.57-0.96 p < 0.01) and after PS matching cohort (HR: 0.65, 95% CI: 0.46-0.94, p < 0.01). CONCLUSIONS: Combined with the results of previous studies, total intravenous anesthesia has been shown to be superior to inhalation anesthesia in terms of overall survival for gastric cancer patients undergoing surgical treatment. The selection of intravenous or inhalation anesthesia for gastric cancer surgery should take into account the long-term prognosis of the patient.

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