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1.
J Oral Implantol ; 2024 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-38530824

RESUMO

This study evaluated clinical survival rates of 170 Morse taper implants through clinical and mechanical parameters in different therapeutic approaches such as single crowns, fixed partial prostheses and fixed full-arch prostheses. Patients referred to the Center on Education and Research on Dental Implants from May 2017 to July 2018 with the indication for dental implants therapy, aged >18 years, without periodontal disease, recent evidence of inflammatory activity or other oral disorders, current pregnancy, uncontrolled diabetes mellitus or heavy smoking habit were included in this study. After 12 weeks of healing since the implants were placed in the mandible and after 16 weeks following implants placed in the maxilla, patients returned to the Center for prosthetic rehabilitation. After implant therapy, all patients underwent periodical, clinical and prosthetic examinations every six months. The implant was used as a unit of evaluation for all analysis parameters. Prosthetic restorations involved 109 fixed reconstructions in function. Few prosthetic complications were reported (6.55%). Twenty implants were rehabilitated with cemented prostheses; from those, one crown suffered a loss in retention/decementation. Of the 148 implants rehabilitated with screwed-retained prostheses, 6.76% suffered prosthetic screw loosening. The cumulative implant survival rate was 98.2%. When peri-implant tissue health was evaluated, the keratinized mucosa band appeared to be related to peri-implant tissue stability. Thus, Morse taper implants represented a successful procedure for implant rehabilitation, with a high cumulative implant survival rate, low prevalence of biological and prosthetic complications and good stability of peri-implant tissues over the period assessed.

2.
J Esthet Restor Dent ; 2024 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-38501610

RESUMO

OBJECTIVE: The Journal of Esthetic and Restorative Dentistry (JERD) stands out as one of the most prominent international journals publishing research in esthetic dentistry. This study analyzed articles published by JERD since the year 2000 through bibliometric analysis. METHODOLOGY: The search was conducted in January 2024 using Scopus. The following data were extracted from the articles: citation count, year, language, access type, funding agency, study design, theme (general and specific), country, institution, authors, and keywords. The VOSviewer software was used to generate collaborative network maps among the data. Dimensions were consulted to measure altmetric data. Google Trends was used to investigate the global popularity of JERD research. RESULTS: A total of 1394 articles were included in this analysis. Citation count ranged from 0 to 625 (average: 16.9). Articles were published between 2000 and 2023. Laboratory studies were more prevalent (n = 850), with the most investigated general theme being restorative procedures (n = 882), and the highlighted specific theme being the use of composite resin (n = 327). The United States had the highest number of articles (n = 640), with the diverse distribution among other countries. The most common keyword was "cad/cam" (n = 63). VOSviewer demonstrated high collaboration among countries. Intense mentions were identified primarily on Facebook. According to Google Trends, Egypt was the country that searched for JERD the most. CONCLUSIONS: JERD exhibited significant growth in the number of published articles and their diversity by topics, types, origin (country), number of citations, and impact factor. CLINICAL SIGNIFICANCE: The JERD is a journal that publishes studies influencing clinical practice. Identifying the key characteristics of this journal is essential for charting future paths.

3.
Artigo em Inglês | MEDLINE | ID: mdl-37232688

RESUMO

This study assessed the histologic and histomorphometric changes of free gingival grafts in a canine model after mechanical expansion. A total of eight epithelialized tissue samples were obtained from the palate of eight Beagle dogs. Samples were cut in half and separated into two groups: the test group, in which a device was used to expand the grafts, and the control group, without expansion. After histologic processing, samples were evaluated by qualitative histology and histomorphometry. Histologic analysis revealed some differences in epithelial cell morphology and keratin layer integrity in the test group compared to the control group. Differences in histomorphometric parameters for the expanded and nonexpanded groups, including the thickness of the keratin layer (15.4 ± 13.4 µm and 32.3 ± 18.1 µm, respectively), thickness of the epithelium (398.0 ± 168.0 µm and 368.4 ± 142.8 µm, respectively), and the area occupied by collagen fibers in the connective tissue (62.0% ± 11.0% and 55.8% ± 7.6%, respectively), were not statistically significant (P < .05). Despite some changes in qualitative histology, free gingival grafts maintained their histomorphometric characteristics after mechanical expansion. These data provide a scientific basis for the use of mechanical expansion as a possible procedure to reduce the morbidity of autogenous grafts because a single soft tissue sample can be expanded before grafting. Int J Periodontics Restorative Dent 2023;43:e89-e97. doi: 10.11607/prd.5752.


Assuntos
Gengiva , Procedimentos Cirúrgicos Bucais , Cães , Animais , Gengiva/cirurgia , Tecido Conjuntivo/transplante , Epitélio/patologia , Queratinas
4.
Int J Oral Maxillofac Implants ; 38(2): 226-238, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37083911

RESUMO

Purpose: To compare different socket sealing approaches for alveolar ridge preservation and assess the dimensional changes and histologic characteristics of soft and hard tissues in a 4- to 6-month period. Material and Methods: A total of 22 patients with indicated single-tooth extraction in the maxillary nonmolar region were eligible for this study. After CBCT scanning and minimally traumatic tooth extraction, the alveolar sockets were filled with demineralized bovine bone mineral with collagen (DBBM-C) in patients from all groups except for those in the control group. Patients were divided into groups for socket sealing as follows: unsealed/spontaneous healing (control; n = 6), collagen matrix (n = 5), collagen membrane (n = 5), and autogenous graft (n = 6). A second CBCT scan was taken 4 to 6 months after extraction, and a trephine biopsy of soft and hard tissues was collected during implant placement. Tomographic dimensional changes were compared between groups. Intragroup tomographic evaluation and histological analysis were also performed. Results: Analysis of dimensional changes did not detect differences between the socket sealing groups (P > .05). In an intragroup evaluation, the height of the buccal bone and cross-sectional area of the alveolar ridge were significantly lower 4 to 6 months after extraction for the control group (P = .031). Histological analysis revealed that the socket sealing approach had no impact on hard and soft tissue formation. Conclusion: The data from the present study suggest that socket sealing with a collagen matrix, a collagen membrane exposed to the oral cavity, or an autogenous punch graft had no difference in the effects on volumetric maintenance and tissue formation in a period of 4 to 6 months.


Assuntos
Perda do Osso Alveolar , Aumento do Rebordo Alveolar , Humanos , Animais , Bovinos , Alvéolo Dental/diagnóstico por imagem , Alvéolo Dental/cirurgia , Processo Alveolar/diagnóstico por imagem , Processo Alveolar/cirurgia , Colágeno/uso terapêutico , Extração Dentária/métodos , Cicatrização , Aumento do Rebordo Alveolar/métodos , Perda do Osso Alveolar/diagnóstico por imagem , Perda do Osso Alveolar/prevenção & controle , Perda do Osso Alveolar/cirurgia
5.
Contemp Clin Dent ; 12(2): 143-149, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34220154

RESUMO

AIM: The aim of this study is to compare allogeneic bone grafts associated with platelet-rich plasma (ALBGs-PRP) to autogenous bone grafts (ATBGs) for alveolar reconstructions in patients with cleft lip and palate (CLP). MATERIALS AND METHODS: The Maxillofacial Surgery Service of the Comprehensive Care Center for CLP (CCCLP) in Curitiba (Paraná, Brazil). PATIENTS: Thirty out of 46 patients with 8-12 years of age and pre- or trans-foramen unilateral clefts were operated by the same surgeon. Groups were selected randomly after coin-toss for the first surgery to be ALBG-PRP. INTERVENTIONS: Pre- and post-surgery cleft defect severity was registered by a score system using superimposed digitalized peri-apical radiographs. The hypothesis indicated ABG-PRP to be similar to the ABG was proved. RESULTS: There was no statistically significant difference (P < 0.05) in bone augmentation for the ABG-PRP group (79.88%) when compared to the ABG group (79.9%). CONCLUSION: ABG-PRP is indicated as a successful treatment modality to reduce the need for additional donor sites and reduce morbidity and hospital stay.

6.
Int J Mol Sci ; 23(1)2021 Dec 29.
Artigo em Inglês | MEDLINE | ID: mdl-35008798

RESUMO

Pyroptosis is a caspase-dependent process relevant to the understanding of beneficial host responses and medical conditions for which inflammation is central to the pathophysiology of the disease. Pyroptosis has been recently suggested as one of the pathways of exacerbated inflammation of periodontal tissues. Hence, this focused review aims to discuss pyroptosis as a pathological mechanism in the cause of periodontitis. The included articles presented similarities regarding methods, type of cells applied, and cell stimulation, as the outcomes also point to the same direction considering the cellular events. The collected data indicate that virulence factors present in the diseased periodontal tissues initiate the inflammasome route of tissue destruction with caspase activation, cleavage of gasdermin D, and secretion of interleukins IL-1ß and IL-18. Consequently, removing periopathogens' virulence factors that trigger pyroptosis is a potential strategy to combat periodontal disease and regain tissue homeostasis.


Assuntos
Doenças Periodontais/patologia , Piroptose , Animais , Apoptose , Humanos , Inflamassomos/metabolismo , Doenças Periodontais/terapia , Fatores de Virulência/metabolismo
7.
J Appl Oral Sci ; 27: e20180317, 2019 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-30810639

RESUMO

BACKGROUND: Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. OBJECTIVE: Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 effects, this study evaluated the outcomes of BMP-2, RA, and BMP-2+RA treatments on in vitro osteogenic differentiation of human adipose-derived stem cells (ASCs) and the signaling pathway(s) involved. MATERIAL AND METHODS: ASCs were treated every other day with basic osteogenic medium (OM) alone or supplemented with BMP-2, RA, or BMP-2+RA. Alkaline phosphatase (ALP) activity was determined using the r-nitrophenol method. Extracellular matrix mineralization was evaluated using von Kossa staining and calcium quantification. Expression of osteonectin and osteocalcin mRNA were determined using qPCR. Smad1, Smad4, phosphorylated Smad1/5/8, BMP-4, and BMP-7 proteins expressions were analyzed using western blotting. Signaling pathway was evaluated using the IPA® software. RESULTS: RA promoted the highest ALP activity at days 7, 14, 21, and 28, in comparison to BMP-2 and BMP-2+RA. BMP-2+RA best stimulated phosphorylated Smad1/5/8 protein expression at day 7 and Smad4 expression at days 7, 14, 21, and 28. Osteocalcin and osteonectin mRNA expressions were best stimulated by BMP-2+RA at day 7. Matrix mineralization was most improved by BMP-2+RA at days 12 and 32. Additionally, BMP-2+RA promoted the highest BMP signaling pathway activation at days 7 and 14, and demonstrated more activation of differentiation of bone-forming cells than OM alone. CONCLUSIONS: In summary, RA increased the effect of BMP-2 on osteogenic differentiation of human ASCs.


Assuntos
Proteína Morfogenética Óssea 2/efeitos dos fármacos , Diferenciação Celular/efeitos dos fármacos , Células-Tronco Mesenquimais/efeitos dos fármacos , Osteogênese/efeitos dos fármacos , Tretinoína/farmacologia , Fosfatase Alcalina/análise , Fosfatase Alcalina/efeitos dos fármacos , Análise de Variância , Western Blotting , Proteína Morfogenética Óssea 2/metabolismo , Diferenciação Celular/fisiologia , Células Cultivadas , Humanos , Células-Tronco Mesenquimais/metabolismo , Osteoblastos/efeitos dos fármacos , Osteocalcina/análise , Osteocalcina/efeitos dos fármacos , Osteogênese/fisiologia , Osteonectina/análise , Osteonectina/efeitos dos fármacos , Valores de Referência , Reprodutibilidade dos Testes , Fatores de Tempo
8.
J. appl. oral sci ; 27: e20180317, 2019. tab, graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-984571

RESUMO

Abstract Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. Objective Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 effects, this study evaluated the outcomes of BMP-2, RA, and BMP-2+RA treatments on in vitro osteogenic differentiation of human adipose-derived stem cells (ASCs) and the signaling pathway(s) involved. Material and Methods ASCs were treated every other day with basic osteogenic medium (OM) alone or supplemented with BMP-2, RA, or BMP-2+RA. Alkaline phosphatase (ALP) activity was determined using the r-nitrophenol method. Extracellular matrix mineralization was evaluated using von Kossa staining and calcium quantification. Expression of osteonectin and osteocalcin mRNA were determined using qPCR. Smad1, Smad4, phosphorylated Smad1/5/8, BMP-4, and BMP-7 proteins expressions were analyzed using western blotting. Signaling pathway was evaluated using the IPA® software. Results RA promoted the highest ALP activity at days 7, 14, 21, and 28, in comparison to BMP-2 and BMP-2+RA. BMP-2+RA best stimulated phosphorylated Smad1/5/8 protein expression at day 7 and Smad4 expression at days 7, 14, 21, and 28. Osteocalcin and osteonectin mRNA expressions were best stimulated by BMP-2+RA at day 7. Matrix mineralization was most improved by BMP-2+RA at days 12 and 32. Additionally, BMP-2+RA promoted the highest BMP signaling pathway activation at days 7 and 14, and demonstrated more activation of differentiation of bone-forming cells than OM alone. Conclusions In summary, RA increased the effect of BMP-2 on osteogenic differentiation of human ASCs.


Assuntos
Humanos , Osteogênese/efeitos dos fármacos , Tretinoína/farmacologia , Diferenciação Celular/efeitos dos fármacos , Proteína Morfogenética Óssea 2/efeitos dos fármacos , Células-Tronco Mesenquimais/efeitos dos fármacos , Osteoblastos/efeitos dos fármacos , Osteogênese/fisiologia , Valores de Referência , Fatores de Tempo , Osteocalcina/análise , Osteocalcina/efeitos dos fármacos , Osteonectina/análise , Osteonectina/efeitos dos fármacos , Diferenciação Celular/fisiologia , Células Cultivadas , Western Blotting , Reprodutibilidade dos Testes , Análise de Variância , Fosfatase Alcalina/análise , Fosfatase Alcalina/efeitos adversos , Proteína Morfogenética Óssea 2/metabolismo , Células-Tronco Mesenquimais/metabolismo
9.
J Prosthet Dent ; 120(2): 276-281, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29551373

RESUMO

STATEMENT OF PROBLEM: Laboratory procedures, such as dipping in coloring and fluorescent liquids, can be used to improve the optical properties of zirconia. However, information is lacking on the effect of these liquids. PURPOSE: The purpose of this in vitro study was to evaluate the color differences and degree of fluorescence of zirconia (3Y-TZP) treated with coloring and fluorescent liquids before and after an accelerated aging protocol. MATERIAL AND METHODS: Forty disk-shaped specimens of 3Y-TZP were fabricated by milling and separated according to the laboratory treatment performed: white zirconia (control group); zirconia treated with coloring liquid (A2 group); zirconia treated with fluorescent liquid (fluorescent group); and zirconia treated with both liquids (A2 fluorescent group). The L*a*b* coordinates before aging (T0) were obtained with a spectrophotometer, and the degree of fluorescence was measured. The disks were subjected to accelerated aging for 1 hour (T1) and 5 hours (T2). Measurements were made before and after each time interval. Color differences (ΔE00) were calculated using the CIEDE2000 formula and analyzed by 2-way ANOVA. Lightness (ΔL'), chroma (ΔC'), and hue differences (ΔH') were analyzed by multivariate ANOVA. Degrees of fluorescence were obtained as percentages and were analyzed by 2-way ANOVA. Multiple comparisons were performed by the Tukey HSD test (α=.05). RESULTS: Color differences were observed when 3Y-TZP disks were treated with coloring (7.91 ΔE00), with fluorescent liquid (5.81 ΔE00), and with both liquids (5.52 ΔE00). Accelerated aging resulted in color differences in the T2 A2 group (6.74 ΔE00) and at both times evaluated in the fluorescent group (T1=8.59 ΔE00 and T2=8.47 ΔE00) (P<.001). In the A2 fluorescent group, the degree of fluorescence was not influenced significantly (P>.05). The use of fluorescent liquid influenced the degree of fluorescence in the fluorescent group (T0=20%). CONCLUSIONS: Significant differences in color, lightness, chroma, and hue were achieved in all tested groups before and after aging. The degree of fluorescence was statistically different only in the fluorescent group and was not influenced by accelerated aging.


Assuntos
Cor , Corantes Fluorescentes/química , Pigmentação em Prótese , Zircônio/química , Análise de Variância , Cerâmica/química , Corantes , Materiais Dentários , Porcelana Dentária/química , Estética Dentária , Humanos , Teste de Materiais , Análise Multivariada , Espectrofotometria , Fatores de Tempo
10.
J Appl Oral Sci ; 26: e20170065, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29489934

RESUMO

Considering oral diseases, antibiofilm compounds can decrease the accumulation of pathogenic species such as Streptococcus mutans at micro-areas of teeth, dental restorations or implant-supported prostheses. OBJECTIVE: To assess the effect of thirteen different novel lactam-based compounds on the inhibition of S. mutans biofilm formation. MATERIAL AND METHODS: We synthesized compounds based on γ-lactones analogues from rubrolides by a mucochloric acid process and converted them into their corresponding γ-hydroxy-γ-lactams by a reaction with isobutylamine and propylamine. Compounds concentrations ranging from 0.17 up to 87.5 µg mL-1 were tested against S. mutans. We diluted the exponential cultures in TSB and incubated them (37°C) in the presence of different γ-lactones or γ-lactams dilutions. Afterwards, we measured the planktonic growth by optical density at 630 nm and therefore assessed the biofilm density by the crystal violet staining method. RESULTS: Twelve compounds were active against biofilm formation, showing no effect on bacterial viability. Only one compound was inactive against both planktonic and biofilm growth. The highest biofilm inhibition (inhibition rate above 60%) was obtained for two compounds while three other compounds revealed an inhibition rate above 40%. CONCLUSIONS: Twelve of the thirteen compounds revealed effective inhibition of S. mutans biofilm formation, with eight of them showing a specific antibiofilm effect.


Assuntos
Antibacterianos/farmacologia , Biofilmes/efeitos dos fármacos , Lactonas/farmacologia , Streptococcus mutans/efeitos dos fármacos , beta-Lactamas/farmacologia , Análise de Variância , Antibacterianos/síntese química , Biofilmes/crescimento & desenvolvimento , Contagem de Colônia Microbiana , Relação Dose-Resposta a Droga , Violeta Genciana , Lactonas/síntese química , Testes de Sensibilidade Microbiana , Viabilidade Microbiana/efeitos dos fármacos , Microscopia Eletrônica de Varredura , Plâncton/efeitos dos fármacos , Plâncton/crescimento & desenvolvimento , Reprodutibilidade dos Testes , Streptococcus mutans/crescimento & desenvolvimento , Resistência beta-Lactâmica/efeitos dos fármacos , beta-Lactamas/síntese química
11.
J. appl. oral sci ; 26: e20170065, 2018. graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-893689

RESUMO

Abstract Considering oral diseases, antibiofilm compounds can decrease the accumulation of pathogenic species such as Streptococcus mutans at micro-areas of teeth, dental restorations or implant-supported prostheses. Objective To assess the effect of thirteen different novel lactam-based compounds on the inhibition of S. mutans biofilm formation. Material and methods We synthesized compounds based on γ-lactones analogues from rubrolides by a mucochloric acid process and converted them into their corresponding γ-hydroxy-γ-lactams by a reaction with isobutylamine and propylamine. Compounds concentrations ranging from 0.17 up to 87.5 μg mL-1 were tested against S. mutans. We diluted the exponential cultures in TSB and incubated them (37°C) in the presence of different γ-lactones or γ-lactams dilutions. Afterwards, we measured the planktonic growth by optical density at 630 nm and therefore assessed the biofilm density by the crystal violet staining method. Results Twelve compounds were active against biofilm formation, showing no effect on bacterial viability. Only one compound was inactive against both planktonic and biofilm growth. The highest biofilm inhibition (inhibition rate above 60%) was obtained for two compounds while three other compounds revealed an inhibition rate above 40%. Conclusions Twelve of the thirteen compounds revealed effective inhibition of S. mutans biofilm formation, with eight of them showing a specific antibiofilm effect.


Assuntos
Streptococcus mutans/efeitos dos fármacos , Biofilmes/efeitos dos fármacos , beta-Lactamas/farmacologia , Lactonas/farmacologia , Antibacterianos/farmacologia , Plâncton/crescimento & desenvolvimento , Plâncton/efeitos dos fármacos , Streptococcus mutans/crescimento & desenvolvimento , Microscopia Eletrônica de Varredura , Contagem de Colônia Microbiana , Testes de Sensibilidade Microbiana , Reprodutibilidade dos Testes , Análise de Variância , Biofilmes/crescimento & desenvolvimento , Resistência beta-Lactâmica/efeitos dos fármacos , beta-Lactamas/síntese química , Relação Dose-Resposta a Droga , Viabilidade Microbiana/efeitos dos fármacos , Violeta Genciana , Lactonas/síntese química , Antibacterianos/síntese química
12.
Compend Contin Educ Dent ; 38(10): e9-e12, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29140100

RESUMO

Excessive gingival display (EGD) is a challenge for dentists attempting to provide their patients a pleasant smile. EGD associated with hyperactivity of the smile elevator muscles can be treated with various surgical techniques; regardless of which technique is used, to achieve a predictable result with long-term stability limiting upper lip movement when the patient smiles, a firm muscle containment is imperative. This report describes an innovative suture procedure associated with a lip repositioning technique aimed at maintaining the traction and containment of the smile elevator muscles. This case demonstrates a successful and stable result for excessive gingival exposure, addressing and satisfying a patient's esthetic concerns.


Assuntos
Estética Dentária , Músculos Faciais/cirurgia , Gengivectomia/métodos , Lábio/cirurgia , Sorriso/fisiologia , Técnicas de Sutura , Adulto , Feminino , Humanos , Lábio/anatomia & histologia , Satisfação do Paciente
13.
Implant Dent ; 26(6): 832-840, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28885317

RESUMO

OBJECTIVE: To evaluate clinically and radiographically, in humans, the healing of maxillary third molars postextraction sockets after application of different ridge preservation techniques 3 months after tooth extraction. MATERIALS AND METHODS: Twenty-six sockets (13 patients) were randomly assigned to 4 treatment modalities: deproteinized bovine bone mineral with 10% collagen (DBBM-C), poly(D,L-lactide-co-glycolide) with hydroxyapatite/ß-TCP scaffold (PLGA/HA), PLGA/HA/ß-TCP with 2.0% simvastatin scaffold (PLGA/HA/S), and spontaneous healing (control). Clinical complications were assessed, and cone-beam computed tomographies were taken in 5 patients 3 months after surgeries. For statistical purposes, the Fisher exact test was used (P < 0.05). RESULTS: After 3 months, 6 of 9 grafts from the PLGA/HA group were lost (P < 0.05). PLGA/HA/S' loss was only 2 of 8 (P > 0.05), but no loss was observed in the DBBM-C group. Pain was present in 3 of 8 sites that lost the graft (37.5%) (P > 0.05) and infection in 1 of 8 (12.5%) (P > 0.05), with these only occurring in the PLGA/HA group. CONCLUSIONS: Poly (D, L-lactide-co-glycolide) with hydroxyapatite/ß-TCP (PLGA/HA/ß-TCP) scaffolds, with and without simvastatin, failed to obtain the initial expected results and presented more complications. Scaffolds with simvastatin showed to be superior, with less clinical complications than scaffolds without simvastatin.


Assuntos
Aumento do Rebordo Alveolar/métodos , Materiais Biocompatíveis/uso terapêutico , Substitutos Ósseos/uso terapêutico , Fosfatos de Cálcio/uso terapêutico , Colágeno/uso terapêutico , Durapatita/uso terapêutico , Ácido Láctico/uso terapêutico , Maxila/cirurgia , Minerais/uso terapêutico , Dente Serotino/cirurgia , Ácido Poliglicólico/uso terapêutico , Sinvastatina/uso terapêutico , Alicerces Teciduais , Extração Dentária , Tomografia Computadorizada de Feixe Cônico , Feminino , Humanos , Masculino , Projetos Piloto , Copolímero de Ácido Poliláctico e Ácido Poliglicólico , Porosidade , Estudos Prospectivos , Adulto Jovem
14.
ImplantNewsPerio ; 2(5): 885-892, set.-out. 2017. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-877294

RESUMO

Este artigo teve por objetivo apresentar um caso clínico cuja prótese provisória utilizou um componente protético multifuncional de PEEK. Este é um polímero biocompatível personalizável e de boa aderência às resinas. O caso descrito é um implante imediato com carga imediata na região do 21. Foi realizado um approach palatino do implante, preenchimento do gap vestibular com um enxerto aloplástico (Nanosynt), um provisório imediato utilizando um componente provisório multifuncional de PEEK e um dente de estoque. O caso foi acompanhado até a fase de confecção da prótese defi nitiva, na qual foi verifi cada a arquitetura dos tecidos peri-implantares quanto à saúde e manutenção. Na Implantodontia contemporânea, o PEEK é a opção biológico-funcional com melhor custo-benefício nos casos de implantes colocados e carregados imediatamente.


The aim of this article was to present a clinical case where the provisional restoration was fabricated over a multifunctional PEEK healing abutment. This biocompatible polymer can be customized and has excellent bond strength to resin composites. A dental implant was loaded at the region of tooth 21. After a palatal approach for implant placement, the buccal gap was fi lled with an alloplastic graft (Nanosynt). Then, the immediate restoration was fabricated with the multifunctional PEEK and an acrylic tooth form. At the delivery of the defi nitive restoration, the peri-implant soft tissue health and architecture were preserved. In the contemporary implant dentistry, PEEK abutments provide the best biological and functional option with a signifi cant cost-benefi t ratio for cases of immediate implant loading


Assuntos
Humanos , Feminino , Adulto , Materiais Biocompatíveis , Implantação Dentária , Implantes Dentários para Um Único Dente , Prótese Parcial Temporária , Carga Imediata em Implante Dentário , Alvéolo Dental/cirurgia
15.
Rev. odontol. Univ. Cid. São Paulo (Online) ; 29(1): 48-56, Jan.-Abr. 2017.
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-859116

RESUMO

Implantes inclinados atualmente são utilizados como uma alternativa cirúrgica e protética. Por tanto, estudos in vitro demonstram que o seu uso aumenta a concentração de tensão no osso cortical peri-implantar e questionasse se esse fator pode levar ao insucesso da reabilitação oral estética. O objetivo do presente artigo foi avaliar a informação relacionada com a influência de forças funcionais sobre a biomecânica de implantes inclinados nas reabilitações orais implantossuportadas. No intuito de investigar essa hipótese, foi realizada uma revisão da literatura e busca de informações existentes em artigos científicos indexados ao PubMed, que avaliassem o efeito da distribuição das tensões na interface osso-implante de implantes inclinados, através do método de análise dos elementos finitos. Os resultados mostraram que o uso de implantes inclinados aumenta a concentração de tensões no osso cortical peri-implantar sob simulação de cargas parafuncionais. No entanto, análises in-vitro não podem prever de forma precisa o comportamento dos tecidos biológicos. Apesar dessa limitação dos estudos, pode-se concluir que elevados picos de tensões poderiam comprometer os limites de resistência do osso cortical, podendo levar a falhas do conjunto osso-implante. Todavia, quando associados a reabilitações de próteses múltiplas, os implantes inclinados mudam sua biomecânica, favorecendo a distribuição e redução das tensões e o aumento da estabilidade das reabilitações como um todo.


Tilted implants are currently used as a surgical and prosthetic's alternative. Therefore, in-vitro studies demonstrate that their use increases the stress concentration in the peri-implant cortical bone and it wonders whether this can lead to the failure of an aesthetic oral rehabilitation. The aim of this paper was to assess information related to the influence of functional forces on the biomechanics of tilted implants in implant oral rehabilitation. In order to investigate this hypothesis, a literature review was made in scientific articles indexed to PubMed, to assess the effect of the stress distribution in the bone-implant interface of tilted implants, through the analysis of the finite element method. The results showed that the use of tilted implants increases the concentration of stresses in the peri-implant cortical bone under the simulation of parafunctional loads. However, in-vitro tests may not accurately predict the behavior of biological tissues. Despite this limitation of the study, it can be concluded that high peaks of tension could compromise the strength limits of cortical bone, leading to failure of the bone-implant joint. However, when associated with multiple rehabilitations, the titled implants change their biomechanics, favoring the distribution and reduction of tension and the increase of the stability of restorations as a whole.


Assuntos
Implantes Dentários , Reabilitação Bucal , Próteses e Implantes , Análise de Elementos Finitos
16.
Case Rep Dent ; 2017: 8562050, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28487780

RESUMO

The aim of the current study was to analyse the planktonic growth of Streptococcus mutans on the surfaces of three implants retrieved after three different peri-implantitis treatments. Three implants from a male patient with high levels of bone loss were treated by mechanical debridement, chemical decontamination, and implantoplasty. After 4 months of follow-up, the implants were removed. The growth and biofilm formation were measured by spectrophotometry (OD630 nm) and scanning electron microscopy (SEM), after 48 hours of incubation. Results showed an average of Streptococcus mutans planktonic growth over the implants of 0.21 nm (mechanical debridement), 0.16 nm (chemical decontamination), and 0.15 nm (implantoplasty). Data were analysed by ANOVA and Tukey's test (p < 0.05 for chemical decontamination and implantoplasty). Implantoplasty and chemical decontamination showed the lowest levels of planktonic growth, indicating a possible influence of the modification procedures on the titanium surface on the initial biofilm attachment.

17.
Compend Contin Educ Dent ; 38(3): e4-e8, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28257218

RESUMO

Gingival recession can compromise the esthetic appearance, leading to functional problems, hypersensitivity, and root caries. Several techniques have been implicated for root coverage, which includes pedicle grafts, free gingival grafts, connective tissue grafts, and guided-tissue regeneration. The double-papillae flap associated with subepithelial connective tissue is a predictable technique to cover isolated areas with insufficient attached gingiva apical to a recession. This case report demonstrates a surgical alternative to the technique using a sling periosteal suture to stabilize the connective tissue and pedicle flap during the initial phase of healing, increasing the potential of this periodontal procedure for gingival recession coverage.


Assuntos
Tecido Conjuntivo/transplante , Estética Dentária , Retração Gengival/cirurgia , Gengivoplastia/métodos , Retalhos Cirúrgicos , Adulto , Feminino , Humanos , Incisivo , Mandíbula , Técnicas de Sutura , Raiz Dentária/cirurgia
18.
ImplantNewsPerio ; 1(7): 1357-1367, out.-nov. 2016. ilus
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-848033

RESUMO

O objetivo deste trabalho foi apresentar um caso clínico de reabilitação entre dentes e implantes. Na situação inicial, havia escurecimento do dente 11 e ausência do dente 22, sobre o qual estava instalada uma prótese parcial removível. Uma intensa reabsorção óssea na região do dente ausente foi observada através de análises clínica e tomográfica. A técnica de expansão óssea associada ao deslocamento vestibular de tecido conjuntivo palatino, conhecido como "técnica do rolo", foi realizada, juntamente à instalação de implante cone-morse (Arcsys). Após quatro meses, foi realizada a reabertura. Selecionou-se um munhão universal angulável (Arcsys), o qual teve sua angulação personalizada com base na posição obtida através de um referenciador angular, e uma prótese provisória cimentada foi confeccionada sobre este. Um preparo para coroa metalocerâmica foi realizado no dente 11 e sobre o elemento 21, além da substituição das restaurações antigas, também foi realizada faceta em resina composta. Assim, o caso foi finalizado com uma coroa metalocerâmica sobre implante e uma coroa metalocerâmica sobre dente, entremeadas por dente natural facetado com resina composta. Apesar da complexidade de um caso clínico envolvendo dentes naturais e próteses, foi possível alcançar um resultado satisfatório e um sorriso esteticamente harmônico.


The aim of this paper was to present a clinical rehabilitation case with teeth and implants. In the clinical scenario, there was darkening of tooth 11 and the lack of tooth 22, where a removable prosthesis was installed. Also, considerable bone resorption was observed after clinical and CBCT exams. In this way, bone expansion technique was associated to the roll technique. Four months after implant placement, (morse taper, Arcsys), the opening procedure was performed. A universal abutment (Arcsys) was selected and angled in real time according a pre-fabricated guiding device, receiving a cemented provisional single-tooth crown. Then, tooth 11 received a dental preparation for fused-to-metal crown, and tooth 21 received a direct composite veneer. Thus, the final scenario was composed by a fused-to-metal crowns over dental implant and tooth, and a natural tooth with resin composite veneer. Despite its complexity, satisfactory results and a harmonious smile were achieved.


Assuntos
Humanos , Feminino , Adulto , Regeneração Óssea , Implantes Dentários para Um Único Dente , Prótese Dentária Fixada por Implante , Prótese Parcial Fixa , Reabilitação Bucal , Transplante de Tecidos
19.
J Int Acad Periodontol ; 18: 102-108, 2016 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-31473698

RESUMO

INTRODUCTION: The rehabilitation of the posterior maxilla with implant-supported prosthesis is often complicated by pneumatization of the maxillary sinus. Bone grafting is commonly required in these cases. Over the years, a number of techniques have been developed for this type of reconstruction. AIM: Present and discuss the possibility of alveolar bone regeneration for subsequent placement of oral implants using Fugazzotto's technique in combination with particulate autograft harvested from the mandibular ramus and a connective tissue pedicle flap to cover the graft. METHODS: A case of a 37-year-old woman with a molar perforated during endodontic treatment and indicated for extraction and implant placement is reported. RESULT AND CONCLUSION: The clinical case showed the possibility of grafting of extraction sites combined with atraumatic elevation of the maxillary sinus floor can be achieved using non-conventional techniques such as Fugazzotto's technique associated with alveolar bone regeneration.

20.
Full dent. sci ; 7(27): 35-47, 2016. ilus
Artigo em Português | BBO - Odontologia | ID: biblio-848383

RESUMO

Os tratamentos de carga imediata com implantes unitários em áreas estéticas apresentam alta previsibilidade e vem sendo uma ferramenta de grande valia para o implantodontista. Apresenta vantagens como a manutenção da arquitetura gengival e dimensão óssea, orientação para uma adequada cicatrização tecidual, estética imediata, conforto para o paciente e diminuição no tempo de edentulismo e de tratamento. Com o objetivo de facilitar o dia a dia do implantodontista, esse artigo descreverá, de maneira simples e didática, como reabilitar regiões anteriores com saúde e estética, e porque alguns cuidados tomados são fundamentais para manter a longevidade e o sucesso do caso (AU).


The immediate loading treatment with single implants in the aesthetic region has high predictability and it has been a valuable tool for implantologists. It has the advantage of maintaining gingival bone architecture and size, orientation for proper tissue healing, immediate aesthetic, and comfort for the patient as well as reduces edentulous period and the whole treatment period. In order to facilitate the routine of implantologists, this study will describe a simple and didactic way to rehabilitate aesthetic regions, and explain why proper care is determinant for the longevity and success of the case (AU).


Assuntos
Humanos , Implantação Dentária , Prótese Dentária Fixada por Implante , Carga Imediata em Implante Dentário , Reabsorção Óssea , Brasil
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