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1.
Nutrition ; 106: 111903, 2022 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-36436333

RESUMO

OBJECTIVES: The Institute of Medicine stratifies the references for daily nutrient intake into age and sex groups, considering that the basal metabolic rate varies according to these aspects, and in most cases, it extrapolates the values calculated for adults to children, because their body weights are different. In this context, this study aimed to evaluate the recommendation for magnesium in children according to energy expenditure. METHODS: This was an observational study using the database of the Social Changes, Asthma and Allergy in Latin America (SCAALA) cohort, which randomly collected information from 1445 children ages 4 to 11 y. Of these, 480 (33%) were part of the present study (children between 7 and 11 y old with eutrophic body mass index and adequate growth). Information on food intake was obtained from the child's parents or legal guardians through a 24-h recall. The population was characterized using static analyses such as the Student t test, Pearson correlation coefficient, and linear regression. RESULTS: The mean age of the sample was 8.5 ± 0.96 y, and 54% were males. The mean magnesium intake was 149 ± 70 mg, with a high correlation observed between energy expenditure and magnesium intake (boys: R, 0.716; P <0.001; girls: R, 0.641; P < 0.001). CONCLUSIONS: The metabolic rate can be considered a reference variable for recommending the daily intake of the studied nutrient, aiming to avoid deficiencies and food poisoning because of poor intake.

2.
Sleep Sci ; 15(3): 363-369, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36158715

RESUMO

Introduction: Insomnia is a common sleep disorder in elderly. Although the HIV-positive population have a similar life expectancy when compared to the general population, some factors may interact with immunity conditions and therefore contribute to a worse prognosis. Objective: This is a review of literature that aims to identify prevalence of insomnia in older HIV-positive patients. Material and Methods: This is a review of literature conducted by using MEDLINE-PubMed, Embase, Cochrane Library, CINAHL, Web of Science, Scopus, SciELO, LILACS, and VHL databases, in addition to conducting manual searches. The terms used for the search were related to prevalence, HIV, insomnia, and advanced age. Inclusion criteria were: cross-sectional, cohort, and longitudinal studies, patients with a previous diagnosis of HIV in old age, studies reporting the frequency of insomnia or insomnia symptoms. The criteria for exclusion were: clinical trials, animal studies, letters, abstracts, conference proceedings, studies with other sleep scales that did not include insomnia. Results: There were 2,805 publications found in the database and a further 10 articles were included manually. Of this total, four were included in this review, resulting in a total of 2,227 participants. The prevalence of insomnia in HIV-positive patients over 50 years varied from 12.5% to 76.5%. Conclusion: The frequency of insomnia was higher in the profile of the population studied than in the general population. This should be clinically relevant in order to adequately treat and impact on the prognosis of those patient.

3.
J Sleep Res ; : e13705, 2022 Aug 26.
Artigo em Inglês | MEDLINE | ID: mdl-36054586

RESUMO

Insomnia and sleep-disordered breathing (SDB) are prevalent sleep disorders. These disorders can therefore be concurrently present - comorbid insomnia and sleep apnea (COMISA). The prevalence of COMISA in the paediatric age range is unclear. As such, phenotypic constructs should help better define this comorbid condition if it exists in children and improve both diagnostic sensitivity and ultimately clinical care outcomes. We aimed to evaluate the frequency of insomnia in children and adolescents referred for evaluation of sleep symptoms suggestive of SDB in one initial (Cohort#1) and verify such findings in an independent cohort (Cohort#2) using a retrospective cross-sectional approach in patients aged 9-19 years presenting at a sleep centre to be evaluated for symptoms of SDB. Cohort #1 comprised 50 consecutive children (58% males; mean [SD] age 13.6 [3.3] years; median [interquartile range, IQR] Epworth Sleepiness Scale score 10 [6-12]) who were evaluated using validated SDB and insomnia questionnaires. Cohort#2 was extracted from electronic medical records and included 384 polysomnographically evaluated children (mean [SD] age 12.9 [3.6] years; mean [SD] body mass index z score 1.27 [0.28]; median Epworth Sleepiness Scale score 9.7 [4-17]). In Cohort #1, 56% were at high risk of SDB, 36% had insomnia alone, and 18% were at high risk of COMISA. The prevalence of COMISA in Cohort #2 was 16%, 72% had SDB alone, and 12% had insomnia alone. In both cohorts, COMISA manifested as increased propensity for sleepiness and fatigue during both waking and daytime. Thus, the presence of COMISA is frequent in the paediatric age range and accompanied by a more prominent symptomatic phenotype.

4.
Arch. bronconeumol. (Ed. impr.) ; 58(6): 490-497, jun. 2022. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-206625

RESUMO

Introduction: Classic cardiovascular risk factors do not explain all the cardiovascular events. Obstructive sleep apnoea (OSA) has been proposed as a potential and prevalent cardiovascular risk factor. Our study aimed to describe the prevalence of OSA in a middle-aged cohort with mild–moderate cardiovascular risk and evaluate its association with atherosclerotic disease. Methods: This is an observational cross-sectional ancillary study of the ILERVAS project which was aimed to study subclinical arterial disease in a cohort with mild–moderate cardiovascular risk. In a sample of consecutive subjects, we performed a sleep study and evaluate OSA prevalence and its association with carotid and femoral atheroma plaques and atherosclerotic burden. Results: Overall, 966 subjects with a median age of 57 years (25–75th percentile; 52–62) and a body mass index (BMI) of 28.5kg/m2 (25.6–31.6) were included. Of these, 72.6% (69.7%–75.3%) had OSA (apnoea–hypopnoea index (AHI)≥5/h); 35.7% (32.8%–38.8%) had mild OSA (AHI 5–14.9/h) and 36.9% (33.9%–39.9%) had moderate/severe OSA (AHI≥15/h). Mean oxygen saturation and the percentage of time with oxygen saturation<90% (CT90) were associated with atherosclerotic burden (eβ (95%CI) 0.932 (0.892, 0.974); 1.005 (1.002, 1.009), respectively) and total plaque (OR (95%CI) 0.88 (0.797,0.971); 1.013 (1.004,1.021), respectively). No association with the AHI or oxygen desaturation index was found. Conclusions: This study confirms a high prevalence of OSA in patients with mild–moderate cardiovascular risk and shows an association between atherosclerotic burden, total and femoral plaque with CT90 and mean oxygen saturation, suggesting the importance of OSA-related hypoxaemia in the induction of atherosclerotic disease. (AU)


Assuntos
Humanos , Pessoa de Meia-Idade , Síndromes da Apneia do Sono , Fatores de Risco , Doenças Cardiovasculares , Estudos Transversais , Placa Aterosclerótica
5.
Sleep Sci ; 15(Spec 1): 278-284, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35273778

RESUMO

Introduction: Studies have shown that narcolepsy patients may present with low serum acylcarnitine levels, demonstrating a dysfunctional beta fatty acid oxidation pathway in these patients. Objective: Evaluate the therapeutic efficacy of L-carnitine as a treatment for narcolepsy patients. Methods: This study runned in form of systematic review. The terms used for the search: ("narcolepsy"[MeSH Terms] OR "narcolepsy"[All Fields]) AND ("carnitine"[MeSH Terms] OR "carnitine"[All Fields] OR "l carnitine"[All Fields]). Were included all surveys published until January 2021, with the diagnosis of narcolepsy, that performed drug treatment with I-carnitine. The clinical endpoints of interest were: excessive daytime sleepiness, dissociative REM sleep manifestations: cataplexy, sleep paralysis, hypnagogic hallucinations, and early REM sleep (REM sleep naps, SOREMP). Results: L-carnitine was found to be well-tolerated and without side effects in all surveys, at dosages ranging from 500 to 510 mg/day. Newborns did not present complications during delivery. Conclusion: This study corroborates the efficacy and good tolerability of L-carnitine therapy as a treatment for patients with narcolepsy, including during pregnancy.

6.
J Clin Med ; 11(5)2022 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-35268504

RESUMO

Type 2 diabetes leads to severe nocturnal hypoxemia, with an increase in apnea events and daytime sleepiness. Hence, we assessed sleep breathing parameters in the prediabetes stage. A cross-sectional study conducted on 966 middle-aged subjects without known pulmonary disease (311 patients with prediabetes and 655 controls with normal glucose metabolism) was conducted. Prediabetes was defined by glycated hemoglobin (HbA1c), and a nonattended overnight home sleep study was performed. Participants with prediabetes (n = 311) displayed a higher apnea-hypopnea index (AHI: 12.7 (6.1;24.3) vs. 9.5 (4.2;19.6) events/h, p < 0.001) and hypopnea index (HI: 8.4 (4.0;14.9) vs. 6.0 (2.7;12.6) events/h, p < 0.001) than controls, without differences in the apnea index. Altogether, the prevalence of obstructive sleep apnea was higher in subjects with prediabetes than in controls (78.1 vs. 69.9%, p = 0.007). Additionally, subjects with prediabetes presented impaired measurements of the median and minimum nocturnal oxygen saturation, the percentage of time spent with oxygen saturations below 90%, and the 4% oxygen desaturation index in comparison with individuals without prediabetes (p < 0.001 for all). After adjusting for age, sex, and the presence of obesity, HbA1c correlated with the HI in the entire population (r = 0.141, p < 0.001), and the presence of prediabetes was independently associated with the AHI (B = 2.20 (0.10 to 4.31), p = 0.040) as well as the HI (B = 1.87 (0.61 to 3.14), p = 0.004) in the multiple linear regression model. We conclude that prediabetes is an independent risk factor for an increased AHI after adjusting for age, sex, and obesity. The enhanced AHI is mainly associated with increments in the hypopnea events.

7.
Nutrients ; 14(5)2022 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-35268075

RESUMO

A large body of evidence demonstrates a relationship between hyperglycemia and increased concentrations of advanced glycation end-products (AGEs). However, there is little information about subcutaneous AGE accumulation in subjects with prediabetes, and whether or not this measurement could assist in the diagnosis of prediabetes is unclear. A cross-sectional study was conducted in 4181 middle-aged subjects without diabetes. Prediabetes (n = 1444) was defined as a glycosylated hemoglobin (HbA1c) level between 39 and 47 mmol/mol (5.7 to 6.4%), and skin autofluorescence (SAF) measurement was performed to assess AGEs. A multivariable logistic regression model and receiver operating characteristic curve were used. The cohort consisted of 50.1% women with an age of 57 [52;62] years, a BMI of 28.3 [25.4;31.6] kg/m2, and a prevalence of prediabetes of 34.5%. Participants with prediabetes showed higher SAF than control participants (2.0 [1.7;2.2] vs. 1.9 [1.7;2.2], p < 0.001). However, HbA1c was not significantly correlated with SAF levels (r = 0.026, p = 0.090). In addition, the SAF level was not independently associated with prediabetes (OR = 1.12 (0.96 to 1.30)). Finally, there was no good cutoff point for SAF to identify patients with prediabetes (AUC = 0.52 (0.50 to 0.54), sensitivity = 0.61, and 1-specificity = 0.56). Given all of this evidence, we can conclude that although there is an increase in SAF levels in participants with prediabetes, the applicability and clinical relevance of the results is low in this population.


Assuntos
Hemoglobina A Glicada , Imagem Óptica , Estado Pré-Diabético , Pele , Estudos Transversais , Feminino , Fluorescência , Hemoglobina A Glicada/análise , Humanos , Masculino , Pessoa de Meia-Idade , Imagem Óptica/métodos , Estado Pré-Diabético/sangue , Estado Pré-Diabético/diagnóstico , Estado Pré-Diabético/diagnóstico por imagem , Pele/química , Pele/diagnóstico por imagem
8.
Indian J Orthop ; 56(2): 216-225, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35140852

RESUMO

OBJECTIVE: The objective was to evaluate the level of evidence about the associated factors and the risk factors of osteonecrosis of femoral head (ONFH) in sickle cell individuals. METHODS: The review was based on the search and selection of studies available in the electronic databases PubMed, SCIELO, LILACS, BVS. As descriptors, the terms of Medical Subject Headings (MeSH) and Health Sciences Descriptors (DeCS) corresponding to "Osteonecrosis", "Necrosis avascular" and "Aseptic necrosis" and "Femoral head" and "sickle cell disease" and "risk factor" and "predictor". RESULTS: Among clinical and laboratorial factors the most promising risk factors were the severity of sickle cell disease and acute chest syndrome. As a result, from studies of a moderate level of quality, blood pressure, body weight, previous trauma, haemoglobin to haematocrit ratio (Hb/HCT), and number of hospitalizations can be highlighted. Others, such as genetic markers and male gender, have also been positively associated in lower quality studies. CONCLUSION: For a better clarification of what the risk factors are for the ONFH, it is necessary to study with populations of different origins, different ages, different profiles of Hb, which present greater methodological rigor and perform a multivariate analysis to control confounding factors. Further study is also needed to understand the genetic determinants of ONFH.

9.
Trop Med Int Health ; 27(3): 244-250, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-35048475

RESUMO

OBJECTIVE: To investigate the association among hearing impairment, school performance, and cognitive function in children and adolescents with sickle cell disease. METHODS: Thirty-one participants with sickle cell disease (SCD) and 31 healthy participants in the control-comparison group (CG), both aged 8-17 years underwent auditory system evaluation (pure tone audiometry and acoustic reflex), were screened for the risks of (central) auditory processing disorder and dysfunction of cognitive function using the Scale of Auditory Behaviors (SAB) and the Mini-Mental State Examination (MMSE), respectively, and were interviewed to obtain clinical data and data on school performance. RESULTS: In the SCD group, eight (25.8%) participants presented with sensorineural hearing loss (SNHL). The group with SCD and SNHL presented a higher occurrence of poor school performance than the group of participants with SCD without SNHL (p = 0.016). The MMSE score for aspects related to attention and calculation in the SCD group with SNHL was lower than in the SCD group without SNHL (p = 0.016). In the SAB, the SCD group with SNHL presented a lower score than the SCD group without SNHL in aspects related to academic performance and attention. CONCLUSION: Hearing impairment in children and adolescents with SCD, specifically SNHL, is associated with poor school performance and enhances the risk of cognitive impairment in terms of attention and calculation.


Assuntos
Desempenho Acadêmico , Anemia Falciforme , Perda Auditiva Neurossensorial , Adolescente , Anemia Falciforme/complicações , Anemia Falciforme/epidemiologia , Audiometria de Tons Puros , Criança , Cognição , Perda Auditiva Neurossensorial/etiologia , Humanos
10.
Int J Infect Dis ; 114: 128-131, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34728345

RESUMO

Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.


Assuntos
Craniossinostoses , Complicações Infecciosas na Gravidez , Infecção por Zika virus , Zika virus , Brasil , Feminino , Humanos , Recém-Nascido , Filogenia , Gravidez , Zika virus/genética , Infecção por Zika virus/diagnóstico , Infecção por Zika virus/epidemiologia
12.
Arch Bronconeumol ; 58(6): 490-497, 2022 Jun.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33741145

RESUMO

INTRODUCTION: Classic cardiovascular risk factors do not explain all the cardiovascular events. Obstructive sleep apnoea (OSA) has been proposed as a potential and prevalent cardiovascular risk factor. Our study aimed to describe the prevalence of OSA in a middle-aged cohort with mild-moderate cardiovascular risk and evaluate its association with atherosclerotic disease. METHODS: This is an observational cross-sectional ancillary study of the ILERVAS project which was aimed to study subclinical arterial disease in a cohort with mild-moderate cardiovascular risk. In a sample of consecutive subjects, we performed a sleep study and evaluate OSA prevalence and its association with carotid and femoral atheroma plaques and atherosclerotic burden. RESULTS: Overall, 966 subjects with a median age of 57 years (25-75th percentile; 52-62) and a body mass index (BMI) of 28.5kg/m2 (25.6-31.6) were included. Of these, 72.6% (69.7%-75.3%) had OSA (apnoea-hypopnoea index (AHI)≥5/h); 35.7% (32.8%-38.8%) had mild OSA (AHI 5-14.9/h) and 36.9% (33.9%-39.9%) had moderate/severe OSA (AHI≥15/h). Mean oxygen saturation and the percentage of time with oxygen saturation<90% (CT90) were associated with atherosclerotic burden (eß (95%CI) 0.932 (0.892, 0.974); 1.005 (1.002, 1.009), respectively) and total plaque (OR (95%CI) 0.88 (0.797,0.971); 1.013 (1.004,1.021), respectively). No association with the AHI or oxygen desaturation index was found. CONCLUSIONS: This study confirms a high prevalence of OSA in patients with mild-moderate cardiovascular risk and shows an association between atherosclerotic burden, total and femoral plaque with CT90 and mean oxygen saturation, suggesting the importance of OSA-related hypoxaemia in the induction of atherosclerotic disease.


Assuntos
Doenças Cardiovasculares , Placa Aterosclerótica , Apneia Obstrutiva do Sono , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/etiologia , Estudos Transversais , Fatores de Risco de Doenças Cardíacas , Humanos , Pessoa de Meia-Idade , Placa Aterosclerótica/complicações , Placa Aterosclerótica/epidemiologia , Prevalência , Fatores de Risco , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/epidemiologia
13.
Rev. port. enferm. saúde mental ; (26): 124-139, dez. 2021. tab, graf
Artigo em Português | LILACS-Express | BDENF - Enfermagem | ID: biblio-1361122

RESUMO

Resumo Introdução: As intervenções na crise em saúde mental representam um dos principais desafios da reforma psiquiátrica e no Brasil é realizada um conjunto de práticas de cuidado firmado na atenção psicossocial. O Centro de Atenção Psicossocial (CAPS) corresponde ao serviço de saúde de caráter aberto, comunitário e de referência na rede pública para a saúde mental. Deve funcionar, em todo território nacional, como dispositivo estratégico para evitar as internações em hospitais psiquiátricos incorporando ao seu funcionamento a lógica antimanicomial. Objetivo: O estudo buscou investigar as intervenções na crise em saúde mental nos CAPS. Metodologia: Realizou-se a revisão sistemática da literatura com artigos publicados entre 2009 e 2019, utilizando-se descritores nas bases de dados do PubMed, Biblioteca Virtual em Saúde, Cochrane Library e PsycINFO. Resultados: Dos 1.111 estudos encontrados, 5 foram incluídos na revisão sistemática, totalizando 70 participantes em diferentes modalidades de CAPS. Os profissionais realizaram ações conforme a proposta da reforma psiquiátrica no Brasil, embora ainda houvesse aqueles que utilizaram a intervenção medicamentosa e a internação psiquiátrica. Conclusões: As ações são implementadas por alguns profissionais, o que deveria ser por todos, tendo em vista que a função estratégica do CAPS é evitar reproduzir ações manicomiais.


Abstract Background: Interventions in the mental health crisis represent one of the main challenges of psychiatric reform and in Brazil a set of care practices based on psychosocial care is carried out. The Psychosocial Care Center (CAPS) corresponds to an open, community and referral health service in the public network for mental health. It must function, throughout the national territory, as a strategic device to avoid admissions to psychiatric hospitals, incorporating anti-asylum logic to its operation. Aim: The study sought to investigate interventions in the mental health crisis at CAPS. Metodology: A systematic literature review was carried out with articles published between 2009 and 2019, using descriptors in the databases of PubMed, Virtual Health Library, Cochrane Library and PsycINFO. Results: Of the 1,111 studies found, 5 were included in the systematic review, totaling 70 participants in different CAPS modalities. The professionals carried out actions according to the psychiatric reform proposal in Brazil, although there were still those who used drug intervention and psychiatric hospitalization. Conclusions: The actions are implemented by some professionals, which should be done by all, considering that the strategic function of CAPS is to avoid reproducing asylum actions.


Resumen Contexto: Las intervenciones en la crisis de salud mental representan uno de los principales desafíos de la reforma psiquiátrica y en Brasil se lleva a cabo un conjunto de prácticas asistenciales basadas en la atención psicosocial. El Centro de Atención Psicosocial (CAPS) corresponde a un servicio de salud abierto, comunitario y de referencia en la red pública de salud mental. Debe funcionar, en todo el territorio nacional, como un dispositivo estratégico para evitar los ingresos a hospitales psiquiátricos, incorporando la lógica anti-asilo a su funcionamiento. Objetivo: El estudio buscó investigar las intervenciones en la crisis de salud mental en CAPS. Metodología: Se realizó una revisión bibliográfica sistemática con los artículos publicados entre 2009 y 2019, utilizando descriptores en las bases de datos de PubMed, Virtual Health Library, Cochrane Library y PsycINFO. Resultados: De los 1,111 estudios encontrados, 5 fueron incluidos en la revisión sistemática, totalizando 70 participantes en diferentes modalidades CAPS. Los profesionales realizaron acciones de acuerdo con la propuesta de reforma psiquiátrica en Brasil, aunque todavía hubo quienes utilizaron la intervención por drogas y la hospitalización psiquiátrica. Conclusiones: Las acciones son implementadas por algunos profesionales, lo cual debe ser realizado por todos, considerando que la función estratégica del CAPS es evitar reproducir acciones de asilo.

14.
Sleep Sci ; 14(2): 155-163, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34381579

RESUMO

Delayed sleep-wake phase disorder (DSWPD) is characterized by sleep onset times, beyond the usual schedules and social conveniences, which potentially impacts on health as well as on school and professional performance. The most common treatment for DSWPD is the light administration (light therapy), through light devices, with or without behavioral instructions. Since there is no consensus in the literature about its efficacy and how it should be processed, this study aims to evaluate the light therapy effectiveness in the delayed sleep-wake phase disorder therapeutics. A systematic review was conducted using the MEDLINE/PubMed, Virtual Health Library Brazil, PsycINFO, Web of Science and Scopus databases along with a hand search until September 2020. The included studies presented participants diagnosed with insomnia or DSWPD, over 18-years old, treated only with morning light therapy, mentioning the light intensity (lux) used, and investigations with a control group. Studies reporting individuals with neurological or psychiatric disorders, shift-workers, or evaluating other sleep disorders were excluded. Among the 411 studies identified, five were selected for this review, resulting in a total sample of 140 individuals. Only two studies produced long-term results, showing that the benefits did not persist. In most studies, there were no statistically significant differences in the variables when comparing the intervention group and the control group. However, there were substantial clinical and laboratory advances in the sleep phase using light therapy when comparing phase advances for the same group concerning baseline values of sleep variables.

15.
Sleep Med ; 84: 283-288, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-34214960

RESUMO

Sleep-disordered breathing (SDB) and insomnia have long been recognized as important sleep disrupters often associated with increased morbidity and mortality. Although they are often seen as divergent conditions, mainly because their cardinal symptoms (excessive daytime sleepiness, and sleep loss) differ, these two sleep disorders present with many common symptoms, which may hinder diagnosis and treatment. In addition to possible bidirectional pathways between SDB and insomnia, other factors such as circadian timing may play a role. In this paper, we review the mechanisms, differential clinical aspects, and implications of Comorbid Insomnia and Sleep Apnea, sometimes termed COMISA.


Assuntos
Distúrbios do Sono por Sonolência Excessiva , Síndromes da Apneia do Sono , Distúrbios do Início e da Manutenção do Sono , Transtornos do Sono-Vigília , Humanos , Sono , Síndromes da Apneia do Sono/complicações , Síndromes da Apneia do Sono/diagnóstico , Síndromes da Apneia do Sono/epidemiologia , Distúrbios do Início e da Manutenção do Sono/epidemiologia
17.
Sleep Sci ; 14(1): 47-54, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34104337

RESUMO

Insomnia is a sleep disorder of high prevalence with somatic and psychic repercussions. The present study aimed to describe the prevalence of insomnia in shift workers, as well as the associated variables: gender, age, marital status, profession and shift work schedule. A systematic review was performed using the descriptors "insomnia" AND "shift work", in the PubMed, SciELO and LILACS databases, including studies that presented frequency of insomnia in shift workers, published between 2000 and 2020, in English or Portuguese, only in individuals over 18-years-old. Review articles, meta-analyzes, studies without socioeconomic information, articles without abstract and articles with participants who presented other comorbidities that justified presence of insomnia or pregnant women were excluded. From 480 studies identified, 5 were included in the analysis, with a total sample of 10,141 participants, of whom 4,183 were shift workers. The prevalence of insomnia in shift workers ranged from 12.8% to 76.4%, higher than estimated for general population. Moreover, a higher prevalence was observed among women and singles, and there was no significant variation with age and profession. On the other hand, a relationship between shift work schedule and onset of insomnia still seems controversial.

20.
Nutrients ; 13(3)2021 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-33808883

RESUMO

Prediabetes is closely related to excess body weight and adipose distribution. For this reason, we aimed to assess and compare the diagnostic usefulness of ten anthropometric adiposity indices to predict prediabetes. Cross-sectional study with 8188 overweight subjects free of type 2 diabetes from the ILERVAS project (NCT03228459). Prediabetes was diagnosed by levels of glycated hemoglobin (HbA1c). Total body adiposity indices [BMI, Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) and Deurenberg's formula] and abdominal adiposity (waist and neck circumferences, conicity index, waist to height ratio, Bonora's equation, A body shape index, and body roundness index) were calculated. The area under the receiver-operating characteristic (ROC) curve, the best cutoff and the prevalence of prediabetes around this value were calculated for every anthropometric index. All anthropometric indices other than the A body adiposity were higher in men and women with prediabetes compared with controls (p < 0.001 for all). In addition, a slightly positive correlation was found between indices and HbA1c in both sexes (r ≤ 0.182 and p ≤ 0.026 for all). None of the measures achieved acceptable levels of discrimination in ROC analysis (area under the ROC ≤ 0.63 for all). Assessing BMI, the prevalence of prediabetes among men increased from 20.4% to 36.2% around the cutoff of 28.2 kg/m2, with similar data among women (from 29.3 to 44.8% with a cutoff of 28.6 kg/m2). No lonely obesity index appears to be the perfect biomarker to use in clinical practice to detect individuals with prediabetes.


Assuntos
Antropometria/métodos , Estado Pré-Diabético/diagnóstico , Adiposidade , Biomarcadores , Peso Corporal , Estudos de Coortes , Estudos Transversais , Diabetes Mellitus Tipo 2 , Feminino , Hemoglobina A Glicada , Humanos , Masculino , Obesidade , Obesidade Abdominal , Sobrepeso , Curva ROC
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