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1.
Artigo em Inglês | MEDLINE | ID: mdl-38007707

RESUMO

PURPOSE: The significance of the underlying literature in clinical guidelines can be weakened by the risk of bias, which could negatively affect the recommendations. Especially in controversial matters, such as fluoride use for caries prevention in children, biased results may be not reliable and lead to incorrect conclusions. This study was performed to detect bias in underlying literature of the German guideline for caries prevention using fluoride in children, where no consensus was reached between paediatricians and paediatric dentists. METHODS: Three tools used for risk of bias assessments of different study designs were RoB 2 for RCTs, ROBINS-I for non-randomized studies, and ROBIS for systematic reviews. For each study cited in the guideline two independent risk of bias assessments were performed. Disagreements were resolved by consensus. RESULTS: Out of 58 papers, 48.3% (n = 28) showed high risk of bias, with the majority in sections regarding fluoride tablets, fluoridated toothpaste, and paediatricians' recommendations. 9 out of 20 recommendations and statements were based on studies with high risk of bias, all of which were in these three controversial sections. 13 out of 29 RCTs showed high risk of bias (44.8%), as all 13 non-randomized trials did, while only 2 of 16 (12.5%) systematic reviews had high risk of bias. CONCLUSION: Considering risk of bias of cited studies in clinical guidelines may result in substantial changes in its recommendations and aid in reaching consensus. Efforts should be made to assess risk of bias of underlying literature in future clinical guidelines.

2.
Eur J Paediatr Dent ; 23(3): 183-188, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36172911

RESUMO

AIM: To evaluate the success rates and potential influencing factors of nitrous oxide sedation for dental treatment in a specialised paediatric dental service. MATERIALS: Medical records of all children treated under nitrous oxide sedation in a specialised pedodontics clinic between 2012 and 2017 were analysed retrospectively for parameters such as age of the patient, experience and change of operating dentists, treatment procedure and success or failure regarding the sedation and treatment. CONCLUSION: Given the high overall success rate of over 90%, nitrous oxide sedation can be a highly effective treatment option for performing dental treatment in pre-cooperative and/or anxious children and adolescents. With age of the children and experience of the dentist, success rates increased.


Assuntos
Anestesia Dentária , Anestésicos Inalatórios , Adolescente , Anestesia Dentária/métodos , Criança , Sedação Consciente/métodos , Assistência Odontológica , Humanos , Óxido Nitroso/uso terapêutico , Estudos Retrospectivos
3.
J Dent ; 111: 103727, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-34119612

RESUMO

OBJECTIVE: The aim of this study was to assess 10-year trends in coronal caries in adults aged 20-83 years using data from the two-representative population-based Studies of Health in Pomerania (SHIP-0/SHIP-Trend-0). METHODS: Repeated cross-sectional data from 4,286 SHIP-0 and 3,913 SHIP-Trend-0 participants were analysed. Carious, filled and missing teeth/surfaces were recorded in a half-mouth design and the DMF-T/S scores and sound surfaces/teeth were calculated according to WHO criteria. Trends in DMF-T/S scores and its single components were presented stratified by age group and sex. RESULTS: A statistically significant decline in coronal caries experience (DMF-T and DMF-S) in adults aged 20 to 83 years as well as for D-T/S components was observed. The proportion of edentulous participants was almost halved from 8.7% (SHIP-0) to 5.1% (SHIP-Trend-0), while the number of M-T declined from 4.4 to 3.5 revealing an overall clear shift to a higher retention rate of teeth. In younger adults (25-34 years) 3.8 more sound teeth (17.2 sound surfaces) were found in average in the mouth and in elderly (65-74 years) a clear shift from extracted to filled teeth was observed (M-T reduced by 5.4, while F-T increased by 4). Regarding sex differences, females had consistently on average higher MF-T/S values, but lower D-T/S values than males. CONCLUSION: A clinically relevant drop in the severity of coronal caries experience in all adult age groups in Northeast Germany shows that not only reductions in caries experience in adolescence translated into adulthood but also later improvements led to long-term oral health.


Assuntos
Cárie Dentária , Perda de Dente , Adolescente , Adulto , Idoso , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Feminino , Humanos , Masculino , Prevalência , Perda de Dente/epidemiologia
4.
Eur Arch Paediatr Dent ; 22(4): 707-713, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33768499

RESUMO

PURPOSE: To investigate the differences of parental acceptance of advanced behaviour management techniques (BMT) in different cultural backgrounds (Germany vs. Jordan). METHODS: A convenience sample of 100 parents each of paediatric patients at the University of Greifswald/Germany and Jordan University/Jordan completed a questionnaire to rate their acceptance of four advanced BMT (passive restraint, active restraint, nitrous oxide sedation, and general anaesthesia) using a five-point Likert scale. RESULTS: In both groups, nitrous oxide sedation was the most accepted advanced BMT (mean 3.78 ± 1.34/3.22 ± 1.50, respectively). The least acceptable technique in Germany was passive restraint (2.05 ± 1.18) and in Jordan general anaesthesia (2.11 ± 1.30). The parents in Germany are significantly more accepting of nitrous oxide sedation than are parents in Jordan (p = 0.010), while parents in Jordan are more willing to accept passive restraint (p = 0.001). The acceptance of all advanced BMT increased significantly in both groups when the treatment was urgent. CONCLUSIONS: Parental cultural background and the urgency of the treatment affect the acceptance of different BMT. Moreover, the parental attitude to the pharmacological technique has changed, as nitrous oxide sedation generally appears to be the most preferred advanced technique in both groups.


Assuntos
Anestesia Dentária , Odontopediatria , Criança , Comportamento Infantil , Sedação Consciente , Cultura , Alemanha , Humanos , Jordânia , Óxido Nitroso , Pais
5.
Eur Arch Paediatr Dent ; 22(5): 783-789, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33582957

RESUMO

BACKGROUND: The data on the distribution and pattern of dental trauma in the primary dentition are very rare. AIM: To investigate primary dental trauma patterns in relation to gender, age, time and cause for a recent paediatric cohort and to compare this with a historic one before German unification. METHODS: This retrospective study compared the patterns of dental trauma injuries at the trauma centre at Greifswald University/Germany for a recent paediatric cohort (2014-16, 103 children) with a historic one (1974-1989, n = 120). The data contained details on etiology, injury types and treatment delivered for 450 injured teeth (247 historic, 203 recent). RESULTS: In both cohorts, the occurrence was more common in males than females (63%/55%, resp.) with an age peak from 2 to 6 years. Maxillary incisors were most affected (89.6%/88.6%, resp.) and periodontal ligament injuries dominated (77.8%/90.3%, resp.). Almost half of the injuries occurred at home (46.6%), mostly due to falling (48.5%) or during playing (37.8%) in the recent paediatric cohort which provided better forensic data due to insurance issues and potential concern about child abuse. Advice and follow up was the most common approach in the recent paediatric cohort (76%). CONCLUSION: Even after 30 years and a change in the health care system due to German unification, the patterns of dental traumatic injuries in the primary dentition were similar.


Assuntos
Traumatismos Dentários , Criança , Pré-Escolar , Feminino , Alemanha/epidemiologia , Humanos , Incisivo/lesões , Masculino , Estudos Retrospectivos , Traumatismos Dentários/epidemiologia , Traumatismos Dentários/terapia , Dente Decíduo
6.
Clin Oral Investig ; 25(4): 2399-2405, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33011846

RESUMO

OBJECTIVES: To assess oral health, caries prevalence, and subsequent complications among recently arrived refugees in Germany and to compare these findings with the German resident population. METHODS: This multicenter cross-sectional study recruited 544 refugees aged 3-75+ years; they were examined at ten registration institutions in four federal states in Germany by two calibrated dentists. The refugees were screened for caries (dmft/DMFT) and its complications (pufa/PUFA); this data was compared to the resident population via the representative national oral health surveys). RESULTS: The deciduous dentition of the 3-year-old refugees had a mean dmft value of 2.62 ± 3.6 compared with 0.48 dmft in the German resident population, and caries increased to 5.22 ± 3.4 for 6-7-year-olds (Germany: 1.73 dmft). Few refugee children had naturally healthy teeth (7% in 6-7-year-olds, Germany: 56%). In the permanent dentition, the gap in caries prevalence between refugees and the German population decreased with age (35-44-year-olds: 10.55 ± 7.1 DMFT; Germany: 11.2), but refugees exhibited more caries defects (35-44-year-olds DT = 3.13 ± 3.0; Germany: 0.5). German residents had more restorations (35-44-year-olds FT = 4.21 ± 4.6). Regarding complications, the 6-7-year-olds exhibited the highest pufa index (0.86 ± 1.4) which decreased in adolescence (13-17-year-olds, 0.18 ± 0.6) and increased in adults (45-64-year-olds, 0.45 ± 0.8). CONCLUSION: The refugees had high caries experience, often untreated caries teeth and more complications compared with the German resident population, especially in children. Closing this gap by extending preventive systems to the refugees would decrease future treatment needs. CLINICAL RELEVANCE: European countries should be prepared for the higher dental treatment needs in recent refugees, especially in children.


Assuntos
Cárie Dentária , Refugiados , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Suscetibilidade à Cárie Dentária , Europa (Continente) , Alemanha/epidemiologia , Humanos , Pessoa de Meia-Idade , Saúde Bucal , Prevalência , Adulto Jovem
7.
Clin Oral Investig ; 24(5): 1623-1636, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32306093

RESUMO

OBJECTIVES: For an ORCA/EFCD consensus, this systematic review assessed the question "How to intervene in the caries process in proximal caries in adolescents and adults". MATERIAL AND METHODS: Separating between the management of initial and cavitated proximal caries lesions, Medline via PubMed was searched regarding non-operative/non-invasive, minimally/micro-invasive and restorative treatment. First priority was systematic reviews or randomized controlled trials (RCTs), otherwise cohort studies. After extraction of data, the potential risk of bias was estimated depending on the study type, and the emerging evidence for conclusions was graded. RESULTS: Regarding non-invasive/non-operative care (NOC), no systematic reviews or RCTs were found. In cohort studies (n = 12) with a low level of evidence, NOC like biofilm management and fluoride was associated with a low proportion and slow speed of progression of initial proximal lesions. Minimally/micro-invasive (MI) treatments such as proximal sealants or resin infiltration (four systematic reviews/meta-analyses) were effective compared with a non-invasive/placebo control at a moderate level of evidence. Data on restorative treatment came with low evidence (5 systematic reviews, 13 RCTs); with the limitation of no direct comparative studies, sample size-weighted mean annual failure rates of class II restorations varied between 1.2 (bulk-fill composite) and 3.8% (ceramic). Based on one RCT, class II composite restorations may show a higher risk of failure compared with amalgam. CONCLUSIONS: Proximal caries lesions can be managed successfully with non-operative, micro-invasive and restorative treatment according to lesion stage and caries activity. CLINICAL RELEVANCE: Proximal caries treatment options like non-operative, micro-invasive and restorative care should be considered individually.


Assuntos
Cárie Dentária , Adolescente , Adulto , Humanos , Biofilmes , Consenso , Cárie Dentária/prevenção & controle , Cárie Dentária/terapia , Materiais Dentários , Restauração Dentária Permanente , Fluoretos/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto
8.
Eur J Paediatr Dent ; 21(1): 74-79, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32183534

RESUMO

AIM: Choosing a paediatric dentist is an important decision for parents. The mechanisms of this selection have hardly been studied. This study assesses the factors influencing parents' decision choosing a specialised paediatric dentist for their child. MATERIALS AND METHODS: A questionnaire consisting of 30 items that could potentially be relevant to decision-making was sent nationwide in Germany to paediatric dentists to be given to the parents of new patients (n=450). Eighty-nine out of 102 returned questionnaires (response rate=22.7%) were evaluated. RESULTS: Parent's and children's experience in previous dental visits played an "important" or "very important" role in choosing a paediatric dentist (78.8% and 62.2%, respectively). The most frequently mentioned recommendation for the paediatric dentist was by friends and acquaintances (86.5%). Recommendations from other dentists were often included in the decision making (60.7%), while specialist journals or Internet portals were less important for the respondents (15% and 19%, respectively). Most of the parents used Internet search engines and the practice website to obtain information. CONCLUSION: Previous negative experience with general dentists was the main reason for visiting a specialised paediatric dentist. Recommendations came mostly from the close social environment and the qualifications were the most important feature for choosing a paediatric dentist.


Assuntos
Atitude Frente a Saúde , Pais , Criança , Comportamento Infantil , Tomada de Decisões , Odontólogos , Humanos , Inquéritos e Questionários
9.
Eur Arch Paediatr Dent ; 20(6): 507-516, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31631242

RESUMO

AIM: To update the exisitng European Academy of Paediatric Dentistry (EAPD) 2009 fluoride guidelines. METHODS: Experts met in Athens, Greece duirng November 2018 for the following groups: I Fluoride toothpastes, II Fluoride gels, rinses and varnishes, III Fluoridated milk, fluoridated salt, tablets/lozenges and drops, IV Water fluoridation. Systematic reviews and meta-analyses were reviewed and discussed for each of the groups. The GRADE system was used to assess the quality of evidence which was judged as HIGH, MODERATE, LOW or VERY LOW based on the assessment of eight criteria which can influence the confidence of the results. Following the quality assessment, GRADE was then used to indicate the strength of recommendation for each fluoride agent as STRONG or WEAK/CONDITIONAL. RESULTS: Parents must be strongly advised to apply an age-related amount of toothpaste and assist/supervise tooth brushing until at least 7 years of age. The EAPD strongly endorses the daily use of fluoride as a major part of any comprehensive programme for the prevention and control of dental caries in children. Regardless of the type of programme, community or individually based, the use of fluoride must be balanced between the estimation of caries-risk and the possible risks of adverse effects of the fluorides. Fluoride use is considered safe when the manufacturer's instructions are followed. Preventive programmes should be re-evaluated at regular intervals and adapted to a patient's or population's needs and risks. CONCLUSIONS: For the majority of European Countries, the EAPD recommends the appropriate use of fluoride toothpaste in conjunction with good oral hygiene to be the basic fluoride regimen.


Assuntos
Cárie Dentária , Fluoretos , Animais , Cariostáticos , Criança , Europa (Continente) , Grécia , Humanos , Odontopediatria , Cremes Dentais
10.
Eur Arch Paediatr Dent ; 20(6): 617-622, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31124081

RESUMO

PURPOSE: Due to rising numbers of dental referral to general anesthesia, more specialized dental treatments under GA were needed in the last decades in Germany. However, there are few studies about it. Therefore, the present study aimed to assess dental treatment and characteristics of the children underwent GA at Greifswald University Clinic in comparison with specialized pediatric private practices in Germany. MATERIALS AND METHODS: This analytical comparative research reviewed the records of all children younger than 18 years old, whose underwent GA at the university dental clinic and three private practices in 2011. All cases were analyzed anonymously, including age, gender, caries levels, diagnostics and dental treatments. RESULTS: About 54% and 50%, respectively, of children who underwent GA at both the university clinic and private practices were under 5 years old. Dental caries were mostly diagnosed among referred children (47.4% and 33.8% at university and private practices, resp.) followed by irreversible pulpitis (19.2% and 22.4%, resp.) and ECC (14.1% and 20.1%, resp.). Dental extractions were often performed at university clinic (40.2%) followed by fillings (33.9%), while more restorations and less extractions were supplied at private practices (47.8% and 16.3%, resp.). CONCLUSIONS: Dental caries and its complications like pulpal problems were the most important reason for children who underwent GA combined with young age (< 5 years). Therefore, a primary preventive approach would be preferable to decrease the number of children in need of comprehensive dental treatment under GA.


Assuntos
Anestesia Dentária , Assistência Odontológica para Crianças , Cárie Dentária , Adolescente , Anestesia Geral , Criança , Pré-Escolar , Assistência Odontológica , Alemanha , Humanos , Estudos Retrospectivos
11.
Eur Arch Paediatr Dent ; 20(4): 319-323, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30600475

RESUMO

BACKGROUND: Behaviour management techniques (BMT) in children are essential to achieve a successful dental treatment, but parents are not equally accepting BMT. AIM: To investigate the parental acceptance of advanced behaviour management techniques used in paediatric dentistry in normal and in emergency situations in Germany. METHODS: Parents bringing their children for dental care answered a questionnaire on the acceptance of four advanced BMT: passive restraint, active restraint, nitrous oxide sedation and general analgesia. The study was conducted in five university dental clinics in Germany. Parents rated overall acceptance of each technique using a five points Likert scale. RESULTS: 136 parents answered the questionnaire. The acceptance of all advanced BMT was significantly higher when the treatment was urgent (p < 0.001, paired sample t test). Nitrous oxide sedation was rated as the most acceptable technique in normal treatment (52.6%) and in emergency situation (68.2%), while passive restraint was the least acceptable technique in both normal (19.9%) and emergency situation (37.8%). CONCLUSIONS: Parents in Germany are more willing to accept advanced BMT in emergency situations, with nitrous oxide being generally the most preferred technique.


Assuntos
Anestesia Dentária , Odontopediatria , Terapia Comportamental , Criança , Comportamento Infantil , Sedação Consciente , Alemanha , Humanos , Óxido Nitroso , Pais
12.
J Dent Res ; 98(1): 61-67, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30216734

RESUMO

Clinical and patient-reported outcomes were reported for carious primary molars treated with the Hall technique (HT) as compared with conventional carious tissue removal and restorations (i.e., conventional restoration [CR]) in a 5-y randomized controlled practice-based trial in Scotland. We interrogated this data set further to investigate the cost-effectiveness of HT versus CR. A total of 132 children who had 2 matched occlusal/occlusal-proximal carious lesions in primary molars ( n = 264 teeth) were randomly allocated to HT or CR, provided by 17 general dental practitioners. Molars were followed up for a mean 5 y. A societal perspective was taken for the economic analysis. Direct dental treatment costs were estimated from a Scottish NHS perspective (an NHS England perspective was taken for a sensitivity analysis). Initial, maintenance, and retreatment costs, including rerestorations, endodontic treatments, and extractions, were estimated with fee items. Indirect/opportunity costs were estimated with time and travel costs from a UK perspective. The primary outcome was tooth survival. Secondary outcomes included 1) not having pain or needing endodontic treatments/extractions and 2) not needing rerestorations. Cost-effectiveness and acceptability were estimated from bootstrapped samples. Significantly more molars in HT survived (99%, 95% CI: 98% to 100%) than in CR (92%; 87% to 97%). Also, the proportion of molars retained without pain or requiring endodontic treatment/extraction was significantly higher in HT than CR. In the base case analysis (NHS Scotland perspective), cumulative direct dental treatment costs (Great British pound [GBP]) of HT were 24 GBP (95% CI: 23 to 25); costs for CR were 29 (17 to 46). From an NHS England perspective, the cost advantage of HT (29 GBP; 95% CI: 25 to 34) over CR (107; 86 to 127) was more pronounced. Indirect/opportunity costs were significantly lower for HT (8 GBP; 95% CI: 7 to 9) than CR (19; 16 to 23). Total cumulative costs were significantly lower for HT (32 GBP; 95% CI: 31 to 34) than CR (49; 34 to 69). Based on a long-term practice-based trial, HT was more cost-effective than CR with HT retained for longer and experiencing less complications at lower costs.


Assuntos
Coroas/economia , Cárie Dentária/economia , Cárie Dentária/terapia , Restauração Dentária Permanente/economia , Restauração Dentária Permanente/métodos , Criança , Análise Custo-Benefício , Inglaterra , Pesquisa sobre Serviços de Saúde , Humanos , Avaliação de Resultados da Assistência ao Paciente , Satisfação do Paciente , Odontopediatria
13.
Community Dent Health ; 35(3): 153-159, 2018 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-30106523

RESUMO

OBJECTIVE: To evaluate the effect of one and half years of an oral health promotion program in primary schools. DESIGN: A cluster-randomized controlled trial. PARTICIPANTS: 740 students aged 9-12 years (48% female) recruited from the fifth grade of 18 different primary schools in West Pomerania, Germany. METHODS: General and oral health education was provided to the teachers in the intervention schools, which they conveyed to their students. No additional measures were conducted in the control schools. Medical and dental school examinations, as well as questionnaires for the students and their parents were conducted at baseline and follow-up. Data were analysed using Poisson regression models. RESULTS: A significant incident rate ratio between caries increment was found, with a 35% higher risk in the control group. However, parents' socioeconomic characteristics modified the effect of the program on their children, as high socio-economic status in the intervention group was associated with 94% reduction in the incidence risk ratio (p ⟨ 0.001). CONCLUSIONS: The program was effective in improving dental health among students with higher socio-economic status. No preventive effect could be found in low socio-economic status groups.


Assuntos
Cárie Dentária/epidemiologia , Cárie Dentária/prevenção & controle , Educação em Saúde Bucal , Saúde Bucal , Criança , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Classe Social
14.
Adv Dent Res ; 29(1): 42-47, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29355413

RESUMO

Modern approaches in caries treatment involve lesion management without tissue removal. Regenerative medicine focuses on replacing damaged tissues with biologically similar tissues. This article discusses the scientific evidence and clinical results for self-assembling peptides in modern caries management. The biomimetic remineralization promoted by self-assembling peptide P11-4 has been proven in vitro as an effective therapy for initial caries. P11-4 was rationally designed to promote formation of hydroxyapatite on its surface. The formulation was optimized to ensure the ability of monomeric P11-4 to penetrate past the subsurface lesions and assembly into a biomatrix within. Furthermore, P11-4 has shown that it assembles into fibers within carious lesions, and promotes the remineralization thereof. In a recent clinical study, the safety and efficacy of P11-4 in treatment of initial caries were evaluated. The additional effect of the application of P11-4 (Curodont Repair) was compared to the application of fluoride varnish (Duraphat) alone in active occlusal initial caries lesions on erupting permanent molars. In the 3- and 6-month recalls, the test group showed, both in the laser fluorescence readings and in the clinical assessment of the caries stage and activity, significantly superior lesion regression compared to the control group. No adverse events, medical complications, or allergic reactions related to the treatments were reported. Clinical applicability of treatment was regarded as satisfactory. Patients were happy to receive noninvasive caries treatments. In conclusion, biomimetic mineralization facilitated by P11-4 in combination with fluoride may present a simple, safe, and effective noninvasive treatment for early carious lesions.


Assuntos
Cárie Dentária/terapia , Oligopeptídeos/farmacologia , Medicina Regenerativa/métodos , Remineralização Dentária/métodos , Materiais Biomiméticos/uso terapêutico , Humanos
15.
J Dent Res ; 97(2): 148-154, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-28892645

RESUMO

Regenerative medicine-based approaches for caries treatment focus on biomimetic remineralization of initial carious lesions as a minimal invasive therapy. In vitro, self-assembling peptide P11-4 enhances remineralization of early carious lesions. To investigate the safety and clinical efficacy of P11-4 for treatment of initial caries, a randomized controlled single-blind study was conducted on children aged >5 y with visible active early caries on erupting permanent molars. Subjects were randomized to either the test group (P11-4 + fluoride varnish) or control group (fluoride varnish alone). Caries were assessed at baseline and at 3 and 6 mo posttreatment per laser fluorescence, a visual analog scale, the International Caries Detection and Assessment System, and Nyvad caries activity criteria. Intention-to-treat analyses were performed, and safety and clinical feasibility of the treatment approaches were assessed. Compared with the control group, the test group showed clinically and statistically significant improvement in all outcomes at 3 and 6 mo. The laser fluorescence readings (odds ratio = 3.5, P = 0.015) and visual analog scale scores (odds ratio = 7.9, P < .0001) were significantly lower for the test group, and they showed regression in the International Caries Detection and Assessment System caries index (odds ratio = 5.1, P = 0.018) and conversion from active to inactive lesions according to Nyvad criteria (odds ratio = 12.2, P < 0.0001). No adverse events occurred. The biomimetic mineralization facilitated by P11-4 in combination with fluoride application is a simple, safe, and effective noninvasive treatment for early carious lesions that is superior to the presently used gold standard of fluoride alone. By regenerating enamel tissue and preventing lesion progression, this novel approach could change clinical dental practice from a restorative to a therapeutic approach. This could avoid additional loss of healthy hard tissue during invasive restorative treatments, potentially enabling longer tooth life and thereby lowering long-term health costs ( ClinicalTrials.gov NCT02724592).


Assuntos
Cárie Dentária/prevenção & controle , Esmalte Dentário/efeitos dos fármacos , Oligopeptídeos/farmacologia , Remineralização Dentária/métodos , Adolescente , Criança , Dentição Permanente , Feminino , Fluoretos Tópicos/farmacologia , Humanos , Masculino , Dente Molar , Método Simples-Cego , Resultado do Tratamento
16.
Br Dent J ; 222(6): 478-483, 2017 Mar 24.
Artigo em Inglês | MEDLINE | ID: mdl-28336976

RESUMO

It is ten years since the first paper on the Hall Technique was published in the British Dental Journal and almost 20 years since the technique first came to notice. Dr Norna Hall a (now retired) general dental practitioner from the north of Scotland had, for many years, been managing carious primary molar teeth by cementing preformed metal crowns over them, with no local anaesthesia, tooth preparation or carious tissue removal. This first report, a retrospective analysis of Dr Hall's treatments, caused controversy. How could simply sealing a carious lesion, with all the associated bacteria and decayed tissues, possibly be clinically successful? Since then, growing understanding that caries is essentially a biofilm driven disease rather than an infectious disease, explains why the Hall Technique, and other 'sealing in' carious lesion techniques, are successful. The intervening ten years has seen robust evidence from several randomised control trials that are either completed or underway. These have found the Hall Technique superior to comparator treatments, with success rates (no pain or infection) of 99% (UK study) and 100% (Germany) at one year, 98% and 93% over two years (UK and Germany) and 97% over five years (UK). The Hall Technique is now regarded as one of several biological management options for carious lesions in primary molars. This paper covers commonly asked questions about the Hall Technique and speculates on what lies ahead.


Assuntos
Cárie Dentária/terapia , Restauração Dentária Permanente/métodos , Humanos , Dente Molar , Fatores de Tempo , Dente Decíduo
17.
Adv Dent Res ; 28(2): 49-57, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27099357

RESUMO

Variation in the terminology used to describe clinical management of carious lesions has contributed to a lack of clarity in the scientific literature and beyond. In this article, the International Caries Consensus Collaboration presents 1) issues around terminology, a scoping review of current words used in the literature for caries removal techniques, and 2) agreed terms and definitions, explaining how these were decided.Dental cariesis the name of the disease, and thecarious lesionis the consequence and manifestation of the disease-the signs or symptoms of the disease. The termdental caries managementshould be limited to situations involving control of the disease through preventive and noninvasive means at a patient level, whereascarious lesion managementcontrols the disease symptoms at the tooth level. While it is not possible to directly relate the visual appearance of carious lesions' clinical manifestations to the histopathology, we have based the terminology around the clinical consequences of disease (soft, leathery, firm, and hard dentine). Approaches to carious tissue removal are defined: 1)selective removal of carious tissue-includingselective removal to soft dentineandselective removal to firm dentine; 2)stepwise removal-including stage 1,selective removal to soft dentine, and stage 2,selective removal to firm dentine6 to 12 mo later; and 3)nonselective removal to hard dentine-formerly known ascomplete caries removal(technique no longer recommended). Adoption of these terms, around managing dental caries and its sequelae, will facilitate improved understanding and communication among researchers and within dental educators and the wider clinical dentistry community.


Assuntos
Consenso , Cárie Dentária , Terminologia como Assunto , Assistência Odontológica , Dentina , Dureza , Humanos
18.
Adv Dent Res ; 28(2): 58-67, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27099358

RESUMO

The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of demineralized dentine. Dentists should manage the disease dental caries and control activity of existing cavitated lesions to preserve hard tissues and retain teeth long-term. Entering the restorative cycle should be avoided as far as possible. Controlling the disease in cavitated carious lesions should be attempted using methods which are aimed at biofilm removal or control first. Only when cavitated carious lesions either are noncleansable or can no longer be sealed are restorative interventions indicated. When a restoration is indicated, the priorities are as follows: preserving healthy and remineralizable tissue, achieving a restorative seal, maintaining pulpal health, and maximizing restoration success. Carious tissue is removed purely to create conditions for long-lasting restorations. Bacterially contaminated or demineralized tissues close to the pulp do not need to be removed. In deeper lesions in teeth with sensible (vital) pulps, preserving pulpal health should be prioritized, while in shallow or moderately deep lesions, restoration longevity becomes more important. For teeth with shallow or moderately deep cavitated lesions, carious tissue removal is performed according toselective removal to firm dentine.In deep cavitated lesions in primary or permanent teeth,selective removal to soft dentineshould be performed, although in permanent teeth,stepwise removalis an option. The evidence and, therefore, these recommendations support less invasive carious lesion management, delaying entry to, and slowing down, the restorative cycle by preserving tooth tissue and retaining teeth long-term.


Assuntos
Cárie Dentária/terapia , Consenso , Polpa Dentária , Dentina , Humanos
19.
Eur Arch Paediatr Dent ; 16(3): 271-6, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25800499

RESUMO

AIM: This study was to investigate the distribution and clinical characteristics of teeth diagnosed with MIH at surface and defect type level in a cohort of German children. METHODS: The study cohort included 242 children diagnosed with MIH which had been recorded during the compulsory dental school examinations of 20 German primary schools. The subjects had been enrolled by cluster sampling. All children attended the second to fourth grade (age 7-10 years, mean 8.1 ± 0.8). The children were examined by five calibrated examiners (kappa = 0.9) after tooth brushing. The recording comprised teeth, surfaces, type and severity of MIH defects and was conducted using a portable light, mirrors and cotton rolls. MIH was registered according to the EAPD criteria. Defects <1 mm were not recorded. Statistical analysis included descriptive statistics and Spearman's correlation. RESULTS: Most affected teeth were first permanent molars (71.4 %) followed by the maxillary central incisors (15.6 %). The most common defects were demarcated opacities (82.2 %), while the remaining 17.8 % of the affected teeth exhibited severe enamel defects. The most frequently affected surface in molars was the occlusal surface (72.4 %); in incisors, it was the buccal surface (73.5 %). There were no atypical restorations in the affected incisors. Different types of MIH defects at various surfaces of the same tooth were common. The number of affected tooth surfaces was positively correlated with the severity of MIH at child (p < 0.001). CONCLUSIONS: The study demonstrates severe enamel defects involving in almost one-fifth of all MIH teeth. The knowledge of the intra-oral distribution and severity of MIH findings at the enamel surface level is important for assessing the treatment needs.


Assuntos
Hipoplasia do Esmalte Dentário/classificação , Criança , Estudos de Coortes , Esmalte Dentário/anormalidades , Hipoplasia do Esmalte Dentário/patologia , Feminino , Alemanha , Humanos , Incisivo/anormalidades , Masculino , Dente Molar/anormalidades , Coroa do Dente/anormalidades
20.
Gesundheitswesen ; 77 Suppl 1: S78-9, 2015 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-24671890

RESUMO

The main goal of this study was the evaluation of an intervention programme for the promotion of health literacy in school-aged children (grade 5-6). The project and the programme were highly accepted, the extension of the annual dental health examination was suitable to collect data within evaluation projects in schools. In spite of positive outcomes, a longer supervision phase would be necessary in order to optimise and to implement other programme components fully.


Assuntos
Avaliação Educacional/estatística & dados numéricos , Educação em Saúde/organização & administração , Letramento em Saúde/organização & administração , Serviços de Saúde Escolar/organização & administração , Estudantes/estatística & dados numéricos , Criança , Saúde da Criança , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Avaliação de Programas e Projetos de Saúde , Instituições Acadêmicas
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