1.
Journal of Sun Yat-sen University(Medical Sciences)
; (6): 534-540, 2023.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-973253
RESUMO
Diabetic kidney disease (DKD) is one of the most common microvascular complications in patients with diabetes. DKD is also the main cause of end-stage renal failure, with very complex pathogenesis. A large number of experiments have confirmed that epigenetic mechanisms, including histone chemical modifications and lipid metabolites 12/15-lipoxygenase (12/15-LO), are involved in regulating the characteristic pathophysiological process of DKD, based on which, this review further explores the pathogenesis of DKD and provides the new research direction for DKD treatment.