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1.
BMC Psychol ; 12(1): 387, 2024 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-38987815

RESUMO

OBJECTIVE: The mainstream view in trait aggression research has regarded the structure as representing the latent cause of the cognitions, emotions, and behaviors that supposedly reflect its nature. Under network perspective, trait aggression is not a latent cause of its features but a dynamic system of interacting elements. The current study uses network theory to explain the structure of relationships between trait aggression features in juvenile offenders and their peers. METHODS: Network analysis was applied to investigate the dynamic system of trait aggression operationalized by the Buss-Perry Aggression Questionnaire in a sample of community youths (Mage = 17.46, N = 715) and juvenile offenders (Mage = 18.36, N = 834). RESULTS: The facet level networks showed that anger is a particularly effective mechanism for activating all other traits. In addition, anger was more strongly associated with physical aggression and the overall network strength was greater in juvenile delinquency networks than in their peers. The item level networks revealed that A4 and A6 exhibited the highest predictability and strength centrality in both samples. Also, the Bayesian network indicated that these two items were positioned at the highest level in the model. There are similarities and differences between juvenile delinquents and community adolescents in trait aggression. CONCLUSION: Trait aggression was primarily activated by difficulty controlling one's temper and feeling like a powder keg.


Assuntos
Agressão , Delinquência Juvenil , Humanos , Agressão/psicologia , Adolescente , Masculino , Delinquência Juvenil/psicologia , Feminino , Criminosos/psicologia , Ira , Grupo Associado , Comportamento do Adolescente/psicologia , Inquéritos e Questionários , Adulto Jovem , Teorema de Bayes
2.
EClinicalMedicine ; 71: 102559, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38549587

RESUMO

Background: The Bowel Ultrasound Score (BUSS) accurately detects therapy-related changes by using the Simple Endoscopic Score for Crohn's disease (SES-CD) as the reference standard. We aimed to evaluate ultrasound remission as a treatment target and its prediction for long-term endoscopic remission. Methods: This single-centre prospective observational study, based at a tertiary referral centre in Milan, Italy, enrolled, between March 1, 2018, and January 31, 2021, adult patients with active CD (SES-CD >2) who were starting biologics. Colonoscopy and IUS was performed at baseline and at 12 months (mean 12.8 ± 4.2). The primary outcome was the predictive value of ultrasound remission at week 12 (BUSS ≤3.52) for long-term endoscopic remission at 12 months. The International Bowel Ultrasound Segmental Activity Score (IBUS-SAS) was also calculated and optimal cut-point to detect endoscopic remission was identified through ROC analysis. Findings: 93 patients with CD were included. Of these, 22 patients (24%) achieved endoscopic remission. Week 12 ultrasound remission predicted endoscopic remission (59% compared with 41% of the patients who were not in ultrasound remission; OR 9.93, 95% CI 3.10-31.80; p < 0.001), while week 12 calprotectin values (<50, <100, <250 µg/g) did not. Week 12 ultrasound activity was associated with failure to achieve long-term endoscopic remission (NPV 87%, PPV 54%). IBUS-SAS cut-off to discriminate endoscopic remission was 22.8 (AUC 0.906). ROC curve comparison showed no-significant difference between BUSS and IBUS-SAS (p = 0.46) for detecting endoscopic remission. Interpretation: Early ultrasound remission predicts long-term endoscopic remission, making it a valuable early treatment target for clinical practice and in clinical trials. Larger multicentre validation studies are warranted to confirm these findings. Funding: None.

3.
Clin Endocrinol (Oxf) ; 99(2): 135-141, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-37357735

RESUMO

OBJECTIVE: In patients with classical congenital adrenal hyperplasia (CAH), virilization affects the brain and external genitalia due to antenatal androgen exposure. There are few studies on how the effects of androgens on brain virilization are reflected in behavior. However, there is no study focused on the adolescence period. The aim of this study was to evaluate the level of aggression in adolescent girls with classical CAH (due to 21 hydroxylase and 11ß hydroxylase deficiency) and to investigate the disease-related factors that may affect aggression. DESIGN: Twenty female and 20 male patients aged 13-20 years, diagnosed with classical CAH, with 21 hydroxylase deficiency and 11ß hydroxylase deficiency, and 20 healthy girls and 20 boys from the same age group were included. The Buss-Perry Aggression Scale (BPAS), which consists of four subgroups measuring physical aggression, verbal aggression, hostility, and angry behaviors, was used. RESULTS: The ages of the male and female patients with CAH were 16.30 ± 2.65 and 16.60 ± 2.41 years, respectively. Total aggression scale scores were 73.3 ± 14.6 in adolescent girls with CAH, 74.1 ± 11.2 in healthy girls, 71.5 ± 14.8 in boys with CAH, and 75.3 ± 14.5 in healthy boys (p > .05). There was no difference between the subscale scores of patients and healthy adolescents. Aggression scores in adolescents with CAH increased significantly with age. CONCLUSIONS: In this study, we found no difference between the aggression scores of adolescents with classical CAH compared to their healthy peers. The total aggression score and subscale were similar in unaffected female adolescents.


Assuntos
Hiperplasia Suprarrenal Congênita , Humanos , Masculino , Feminino , Adolescente , Gravidez , Hiperplasia Suprarrenal Congênita/diagnóstico , Esteroide 21-Hidroxilase , Virilismo , Androgênios , Agressão
4.
Int J Law Psychiatry ; 88: 101890, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37119565

RESUMO

The Buss-Durkee Hostility Inventory (BDHI) is an important assessment scale of hostility in forensic psychiatry. We analyzed the validity and reliability of a Papiamento translation of the BDHI in 134 pre-trial defendants in Curaçao using Exploratory Structural Equation Modeling (ESEM). The reliability of the Direct and Indirect Hostility BHDI-P subscales were good and the reliability of the Social Desirability poor. There was a negative correlation between Direct Hostility and Agreeableness and a positive correlation between Indirect Hostility and Anxiety. We conclude that the BDHI-P has an acceptable measurement quality when used in defendants.


Assuntos
Agressão , Hostilidade , Humanos , Reprodutibilidade dos Testes , Curaçao , Inventário de Personalidade , Psicometria
5.
J Interpers Violence ; 38(5-6): 5305-5328, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36068948

RESUMO

Masculine honor ideology (MHI) refers to a set of beliefs that dictate men must respond aggressively to threat or insult to maintain their ideal masculine reputation. The current study demonstrates the robust relationship between MHI and lifetime aggression outcomes in a national sample of men from the United States. It also details the regional prevalence of MHI and compares these rates across races and regions of the country. Participants included 896 adult United States men (Mage = 35.86, SD = 1.22) recruited on Amazon's Mechanical Turk. It was expected that the odds of endorsing past aggressive behavior and lifetime maladjustment would be increased by stronger adherence to MHI. This hypothesis was supported, and individuals who reported greater MHI adherence also had higher rates of lifetime aggression and maladjustment. Contrary to expectations, White, non-Hispanic men endorsed lower rates of MHI than did other men. Black men adhered more strongly to MHI than White and Hispanic men. It was also expected that men in the Southern and Western United States would endorse greater MHI in comparison to men in the Northeast United States. The hypothesis was only partially supported for White, non-Hispanic men, and it was associated with participant birthplace and their father's birthplace. There were no regional differences in MHI adherence related to the participants' mother's birthplace or where participants lived at survey completion. These findings suggest that MHI may spread more uniformly than prior research suggests and that MHI may have more nuanced cultural considerations that deserve continued empirical investigation.


Assuntos
Agressão , Masculinidade , Masculino , Adulto , Humanos , Estados Unidos , Inquéritos e Questionários , New England
6.
Brain Behav ; 11(7): e02175, 2021 07.
Artigo em Inglês | MEDLINE | ID: mdl-34036747

RESUMO

BACKGROUND: Although aggression is conceptualized as a dimensional construct with violent behavior representing the extreme end of a spectrum, studies on the involvement of personality traits in human aggression have typically only included data representing a restricted spectrum of aggressive behaviors. METHODS: In the current study, we therefore examine whether trait aggression is associated with five-factor model personality traits in an enriched sample of 259 men with a broad continuum of trait aggression, ranging from very low to very high including 39 incarcerated aggressive violent offenders. All participants completed the NEO Personality Inventory-Revised (NEO PI-R) and the Buss-Perry Aggression Questionnaire (BPAQ). The association between each of the five NEO PI-R personality traits and trait aggression (BPAQ) was investigated using five linear regression models, covarying for group status, age and educational level. RESULTS: Higher BPAQ scores were positively associated with Neuroticism and negatively associated with Agreeableness and Conscientiousness. CONCLUSION: Our results indicate that those high in Neuroticism and low in Agreeableness and Conscientiousness are at higher risk of exhibiting aggressive behavior, underlining the relevance of these higher order personality traits in understanding aggressive behavior. We argue that studying individual personality differences should be offered a greater attention within violent and criminal behaviors.


Assuntos
Agressão , Criminosos , Humanos , Masculino , Personalidade , Transtornos da Personalidade , Inventário de Personalidade
7.
Brain Behav ; 11(5): e02043, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33491341

RESUMO

OBJECTIVE: We aim to provide a publicly available Hungarian version of the BPAQ; compare the BPAQ factors to other personality traits; and compare both the original BPAQ factor structure provided by Buss and Perry (J. Pers. Soc. Psychol., 63, 1992, 452), the revised BPAQ-SF factor structure by Bryant and Smith (J. Res. Pers., 35, 2001, 138), and the BAQ by Webster et al. (Aggress. Behav., 40, 2014, 120). METHODS: The validation of the Hungarian version of the BPAQ was carried out on a Hungarian university sample (N = 841). There were three main focuses of data analysis: descriptive statistics, correlations, and confirmatory factor analyses. RESULTS: CFA-related statistics showed an adequate fit for the BPAQ 4 factors; however, contrary to prior validations of BPAQ, we were not able to clearly define the verbal aggression factor. We found that the shorter form of the BPAQ has a better model fit on our sample than the original form, while the model fit of the BAQ was in-between these. BPAQ scales showed low to moderate relationship with the Barratt Impulsivity Scale and Hospital Anxiety and Depression Scale. CONCLUSION: Both the BPAQ and the BPAQ-SF, also the BAQ provide acceptable model fitting on a Hungarian sample of university students. While most of BPAQ items provided adequate loadings on their hypothesized factors, two items (21 and 27) did not. We argue this is the result of conceptual inaccuracy of the original items.


Assuntos
Agressão , Universidades , Análise Fatorial , Humanos , Hungria , Inquéritos e Questionários
8.
J Physiol Anthropol ; 39(1): 20, 2020 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-32795360

RESUMO

BACKGROUND: The specific role of the oxytocin receptor (OXTR) gene polymorphisms in emotional support seeking, related to social norms and culturally normative behavior, has been discussed in several studies. Evidence on the association between aggression and OXTR polymorphisms has also been reported. The goal of the current study was to analyze the effect of the OXTR rs53576 polymorphism, prenatal testosterone effect (second-to-fourth digit ratio, or 2D:4D), and culture on aggression assessed with the Buss-Perry Aggression Questionnaire (BPAQ). METHODS: The data were collected in Russia and Tanzania and included seven ethnic groups of European, Asian, and African origin. The total sample included 1705 adults (837 males, 868 females). All the subjects were evaluated with the BPAQ. As a measure of prenatal androgenization, the second and fourth digits were measured directly from hand, and the digit ratios were calculated. All the participants provided buccal samples, from which genomic DNA was extracted, and the OXTR gene rs53576 polymorphism was genotyped. Statistical analysis was performed using SPSS version 23.0; the alpha level for all analyses was set at 0.05. RESULTS: The ethnic group factor was the most significant predictor of ratings on BPAQ (medium effect size for physical aggression, anger and hostility scales, and low for verbal aggression). To study the effect of sex, the OXTR polymorphism, and prenatal androgenization, we conducted the z-score transformation for BPAQ scales and 2D:4D for each ethnic group and pooled these data into new z-score variables. According to the GLM analysis after leveling the effects of culture (z-transformation), all four scales of BPAQ demonstrated association with sex (main effects), with men scoring higher on physical and verbal aggression and women scoring higher on anger and hostility. Anger and hostility scales were also associated with OXTR polymorphism and 2D:4D of the right hand. The lowest levels of anger and hostility were observed in individuals with the AA genotype, especially in men. CONCLUSIONS: Our data suggest that both oxytocin (OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.


Assuntos
Agressão , Etnicidade , Polimorfismo de Nucleotídeo Único/genética , Grupos Raciais , Receptores de Ocitocina/genética , Adulto , Etnicidade/genética , Etnicidade/estatística & dados numéricos , Feminino , Dedos/anatomia & histologia , Humanos , Masculino , Grupos Raciais/genética , Grupos Raciais/estatística & dados numéricos , Federação Russa , Inquéritos e Questionários , Tanzânia , Adulto Jovem
9.
Psicol. conoc. Soc ; 10(3): 96-113, 2020. tab, graf
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1143563

RESUMO

Resumo: A agressão humana é qualquer comportamento dirigido a outro indivíduo que é executado com a intenção imediata de causar dano. Objetivou-se adaptar e validar o Questionário de Agressão Buss-Perry, versão reduzida, para o português testando estruturas fatoriais já propostas pela literatura. Realizou-se 2 estudos. O primeiro estudo, participaram 200 pessoas, majoritariamente residentes do Estado da Paraíba (88%). Os resultados indicaram que os itens carregaram em seus fatores de origem. No segundo estudo, participaram 207 respondentes, majoritariamente do Estado da Paraíba (96,6%). Os resultados indicaram que a agressão tanto pode ser avaliada de forma específica (agressão física, verbal, raiva e hostilidade), como em um fator geral (agressão geral), isto é, por meio do modelo hierárquico, o qual apresentou bons indicadores de ajuste ao modelo. Como também apresentaram consistência interna satisfatória nos fatores específicos no fator geral tanto no alfa como no Ômega de McDonald, comprovando a fidedignidade e validade de construto dessa escala. Portanto, os dados confirmam o modelo de segunda ordem hipotetizado pela literatura. Esta versão pode ser útil em pesquisas futuras com estudos acerca da agressão, bem como estudos transculturais.


Resumen: La agresión humana es cualquier comportamiento dirigido a otro individuo que se lleva a cabo con la intención inmediata de causar daño. El objetivo fue adaptar y validar el Cuestionario de Agresión de Buss-Perry, versión corta, para el portugués, probando estructuras factoriales ya propuestas por la literatura. Se realizaron dos estudios. En el primer estudio participaron 200 personas, en su mayoría residentes del Estado de Paraíba (88%). Los resultados indicaron que los ítems cargaron en sus factores de origen. En el segundo estudio, participaron 207 encuestados, en su mayoría del Estado de Paraíba (96,6%). Los resultados indicaron que la agresión se puede evaluar de una manera específica (agresión física, verbal, ira y hostilidad), así como en un factor general (agresión general), es decir, a través del modelo jerárquico, que presenta buenos indicadores de ajuste a la modelo Como también presentaron una consistencia interna satisfactoria en los factores específicos en el factor general tanto en el alfa como en el Omega de McDonald's, lo que demuestra la fiabilidad y la validez de constructo de esta escala. Por lo tanto, los datos confirman el modelo de segundo orden hipotetizado por la literatura. Esta versión puede ser útil en futuras investigaciones con estudios sobre agresión, así como en estudios transculturales.


Abstract: Human aggression is any behavior directed at another individual that is carried out with the immediate intention of causing harm. The objective was to adapt and validate the Buss-Perry Aggression Questionnaire, short version, for Portuguese, testing factorial structures already proposed by the literature. Two studies were carried out. The first study involved 200 people, mostly residents of the State of Paraíba (88%). The results indicated that the items loaded in their factors of origin. In the second study, 207 respondents participated, mostly from the State of Paraíba (96.6%). The results indicated that aggression can be assessed both in a specific way (physical, verbal aggression, anger and hostility) as well as in a general factor (general aggression), that is, through the hierarchical model, that presented good indicators of adjustment to the model. As they also presented satisfactory internal consistency in the specific factors in the general factor both in the alpha and in the McDonald's Omega, proving the reliability and construct validity of this scale. Therefore, the data confirm the second order model hypothesized by the literature. This version may be useful in future research with studies on aggression, as well as cross-cultural studies.

10.
Artigo em Inglês | MEDLINE | ID: mdl-29986448

RESUMO

Lead exposure has been associated with psycho-neurological disorders. Elevated blood lead levels have been found in shooters. This study assesses the association between the blood lead levels of shooters and their levels of aggression. An analytical cross-sectional study was conducted in Gauteng, South Africa. Participants were recruited from four randomly selected shooting ranges with three randomly selected archery ranges used as a comparison group. A total of 118 (87 shooters and 31 archers) participants were included in the analysis. Aggressiveness was measured using the Buss-Perry Aggression Questionnaire. Shooters had significantly higher blood lead levels (BLL) compared to archers with 79.8% of shooters versus 22.6% of archers found to have a BLL ≥ 5 μg/dL (p < 0.001). Aggression scores were significantly higher in shooters (p < 0.05) except for verbal aggression. In the bivariate and regression analyses, shooters with BLLs ≥ 10 μg/dL were significantly associated with the hostility sub-scale (p = 0.03, adjusted odds ratio (OR) 2.83, 95% confidence interval (CI) 1.103⁻7.261). Shooters have a significantly higher BLL and aggressiveness compared to archers. However, elevated blood lead levels were significantly associated with hostility only. Interventions need to be put in place to prevent continued exposure and routine screening of populations at risk should be implemented.


Assuntos
Agressão/fisiologia , Exposição Ambiental/efeitos adversos , Armas de Fogo , Hostilidade , Chumbo/sangue , Esportes/psicologia , Violência/psicologia , Adolescente , Adulto , Idoso , Agressão/psicologia , Biomarcadores/sangue , Estudos Transversais , Exposição Ambiental/análise , Exposição Ambiental/estatística & dados numéricos , Feminino , Humanos , Chumbo/toxicidade , Masculino , Pessoa de Meia-Idade , Razão de Chances , Testes Psicológicos , Análise de Regressão , África do Sul , Esportes/fisiologia , Adulto Jovem
11.
Aggress Behav ; 44(3): 306-315, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29427524

RESUMO

Corporal punishment and parental physical abuse often co-occur during upbringing, making it difficult to differentiate their selective impacts on psychological functioning. Associations between corporal punishment and a number of lifetime aggression indicators were examined in this study after efforts to control the potential influence of various forms of co-occurring maltreatment (parental physical abuse, childhood sexual abuse, sibling abuse, peer bullying, and observed parental violence). College students (N = 1,136) provided retrospective self-reports regarding their history of aggression and levels of exposure to childhood corporal punishment and maltreatment experiences. Analyses focused on three hypotheses: 1) The odds of experiencing childhood physical abuse would be higher among respondents reporting frequent corporal punishment during upbringing; 2) Corporal punishment scores would predict the criterion aggression indices after control of variance associated with childhood maltreatment; 3) Aggression scores would be higher among respondents classified in the moderate and elevated corporal punishment risk groups. Strong support was found for the first hypothesis since the odds of childhood physical abuse recollections were higher (OR = 65.3) among respondents who experienced frequent (>60 total disciplinary acts) corporal punishment during upbringing. Partial support was found for the second and third hypotheses. Dimensional and categorical corporal punishment scores were associated significantly with half of the criterion measures. These findings support efforts to dissuade reliance on corporal punishment to manage child behavior.


Assuntos
Sobreviventes Adultos de Maus-Tratos Infantis , Agressão , Bullying/estatística & dados numéricos , Relações Pais-Filho , Pais , Grupo Associado , Abuso Físico , Punição , Irmãos , Adolescente , Adulto , Feminino , Humanos , Masculino , Estudos Retrospectivos , Adulto Jovem
12.
Appl Neuropsychol Adult ; 25(5): 400-409, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-28481122

RESUMO

Neuropsychological research can be advanced through a better understanding of relationships between executive functioning (EF) behavioral competencies and the expression of aggressive behavior. While performance-based EF measures have been widely examined, links between self-report indices and practical real-life outcomes have not yet been established. Executive Functioning Index subscale scores in this sample (N = 579) were linked to trait hostility (Buss-Perry Aggression Questionnaire), aggression in the natural environment (Lifetime Acts of Violence Assessment), and conduct disorder symptoms prior to age 15. Significant associations were found between all of the EFI subscales (Motivational Drive, Organization, Strategic Planning, Impulse Control, and Empathy), trait aggression, and conduct disturbance. Lifetime acts of aggression were predicted by all but Organization scores. Physical injuries inflicted on other(s) were 2 to 4 times more likely to occur among respondents generating low (z < -1) EFI subscale scores. While these EFI relationships were modest in size, they are pervasive in scope. These findings provide support for the potential role of perceived EF deficits in moderating lifetime aggression.


Assuntos
Agressão/psicologia , Transtorno da Conduta/diagnóstico , Transtorno da Conduta/psicologia , Função Executiva/fisiologia , Motivação , Autorrelato , Adolescente , Adulto , Idoso , Feminino , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Inquéritos e Questionários , Adulto Jovem
13.
Aggress Behav ; 43(1): 37-46, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27245759

RESUMO

Previous work has demonstrated that both leaders and other individuals vary in dispositional levels of physical aggression, which are genetically influenced. Yet the importance of individual differences in aggression for attitudes toward foreign policy or context-laden moral choices, such as sacrificing the lives of some for the greater good of many, has yet to be fully explored. Given the global importance of such decisions, we undertook this exploration in a sample of 586 Australians, including 250 complete twin pairs. We found that individuals who scored higher on Buss-Perry's physical aggression scale were more likely to support aggressive foreign policy interventions and displayed a more utilitarian moral calculus than those who scored lower on this scale. Furthermore, we found that the majority of variance in physical aggression lay in genetic factors for men, whereas the majority of the variance was in environmental factors for women. The source of covariation between aggression and political choices also differed between the sexes. A combination of genetic and environmental factors accounted for most of the cross-trait correlations among males, whereas common and unique environmental factors accounted for most of the cross-trait correlations among females. We consider the implications of our results for understanding how trait measures of aggression are associated with foreign policy and moral choices, providing evidence for why and how individuals differ in responding to complex social dilemmas. Aggr. Behav. 43:37-46, 2017. © 2016 Wiley Periodicals, Inc.


Assuntos
Agressão/fisiologia , Interação Gene-Ambiente , Princípios Morais , Política , Comportamento Social , Adulto , Austrália , Comportamento de Escolha , Feminino , Humanos , Masculino , Fenótipo , Fatores Sexuais , Adulto Jovem
14.
Psychopharmacology (Berl) ; 233(4): 571-8, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26630993

RESUMO

INTRODUCTION: The primary objective of this study was to determine if second-generation antipsychotic (SGA) administration was associated with lower aggressiveness scores compared to first-generation (FGA) in schizophrenia (SZ). The secondary objective was to determine if antidepressants, mood stabilizers, and benzodiazepines administration were respectively associated with lower aggressiveness scores compared to patients who were not administered these medications. METHODS: Three hundred thirty-one patients with schizophrenia (N = 255) or schizoaffective disorder (N = 76) (mean age = 32.5 years, 75.5 % male gender) were systematically included in the network of FondaMental Expert Center for Schizophrenia and assessed with the structured clinical interview for DSM-IV Axis I disorders and validated scales for psychotic symptomatology, insight, and compliance. Aggressiveness was measured by the Buss-Perry Aggression Questionnaire (BPAQ) score. Ongoing psychotropic treatment was recorded. RESULTS: Patients who received SGA had lower BPAQ scores than patients who did not (p = 0.01). More specifically, these patients had lower physical and verbal aggression scores. On the contrary, patients who received benzodiazepines had higher BPAQ scores than patients who did not (p = 0.04). No significant difference was found between BPAQ scores of patients respectively being administered mood stabilizers (including valproate), antidepressant, and the patients who were not. These results were found independently of socio-demographical variables, psychotic symptomatology, insight, compliance into treatment, daily-administered antipsychotic dose, the way of antipsychotic administration (oral vs long acting), current alcohol disorder, and daily cannabis consumption. CONCLUSION: The results of the present study are in favor of the choice of SGA in SZ patients with aggressiveness, but these results need further investigation in longitudinal studies. Given the potent side effects of benzodiazepines (especially dependency and cognitive impairment) and the results of the present study, their long-term prescription is not recommended in patients with schizophrenia and aggressive behavior.


Assuntos
Agressão/efeitos dos fármacos , Antipsicóticos/uso terapêutico , Benzodiazepinas/uso terapêutico , Bases de Dados Factuais , Transtornos Psicóticos/tratamento farmacológico , Esquizofrenia/tratamento farmacológico , Adulto , Agressão/psicologia , Antipsicóticos/efeitos adversos , Benzodiazepinas/efeitos adversos , Estudos de Coortes , Estudos Transversais , Bases de Dados Factuais/tendências , Manual Diagnóstico e Estatístico de Transtornos Mentais , Feminino , França/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Transtornos Psicóticos/epidemiologia , Transtornos Psicóticos/psicologia , Esquizofrenia/epidemiologia , Psicologia do Esquizofrênico , Inquéritos e Questionários , Adulto Jovem
15.
J Eval Clin Pract ; 22(3): 421-4, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26696247

RESUMO

INTRODUCTION: This study focused on the widely examined psychosomatic diseases - diabetes mellitus and arterial hypertension as chronic conditions. The Buss-Perry validated questionnaire was used in it to measure aggression in Bulgarian conditions. AIM: To study aggression as a predictor and a connection of the chronic diseases diabetes and hypertension. MATERIAL AND METHODS: The number of the studied people was 142: 54 (38%) men and 88 (62%) women. Thirty-six of them had musculoskeletal disorders (77.8% women and 22.2% men), 54 had diabetes mellitus (29% women and 25% men) and 52 had hypertension (31% women and 21% men). RESULTS: During the statistical analysis of the data, the results from the Buss-Perry questionnaire were compared in the group of patients with hypertension and diabetes mellitus with chronic diseases, related to musculoskeletal disorders. CONCLUSION: The study revealed that there was a statistically significant difference in 95% of the cases between anger, hostility in patients with diabetes, hypertension and musculoskeletal disorders. The highest levels of physical aggression were observed in patients with arterial hypertension, M = 17.32 ± 0.86. The highest average levels of verbal aggression were observed in patients with diabetes, M = 15.24 ± 0.64. The highest levels of anger were observed with patients with hypertension, M = 17.96 ± 0.90, and hostility - in patients with hypertension, M = 19.15 ± 0.86. The comparison between the four Aggression Questionnaire scales showed statistically significant differences between the patients with musculoskeletal disorders and the ones with hypertension and diabetes.


Assuntos
Agressão , Doença Crônica/psicologia , Diabetes Mellitus/psicologia , Hipertensão/psicologia , Bulgária/epidemiologia , Doença Crônica/classificação , Doença Crônica/epidemiologia , Diabetes Mellitus/classificação , Diabetes Mellitus/epidemiologia , Feminino , Humanos , Hipertensão/classificação , Hipertensão/epidemiologia , Masculino , Pessoa de Meia-Idade , Transtornos Psicofisiológicos , Inquéritos e Questionários
17.
Psychiatry Res ; 214(2): 161-8, 2013 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-24011393

RESUMO

The purpose of this report is to describe the relationship between clinical rating assessments of borderline personality disorder (BPD) and regional brain metabolism as measured by positron emission tomography with fluorodeoxyglucuse-F18 (PET-FDG). Fourteen women with BPD underwent PET-FDG scanning in a medication-free state. Correlations were performed on a voxel-by-voxel basis with Buss-Durkee Hostility Index (BDHI) and the Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD) which provides a score for BPD severity. There was a significant negative correlation between glucose metabolism in frontal brain areas and the BDHI. Correlations of brain metabolic changes and diagnostic behavioral rating scale scores (ZAN-BPD) were small and seen mostly in posterior areas. The assessment of the statistical relationship of the BDHI to brain regions was substantially more robust than the correlations of the total ZAN-BPD. This exploratory study illustrates regional metabolic values that are highly related to hostile behavior. Our findings replicate some prior studies that have identified a negative relationship between frontal metabolism and aggression in personality disorders. We have also identified a range of other areas that relate to both positive (representing increased drive) and negative (representing impaired control) hostility scores. The substantially greater correlations of the BDHI compared with the ZAN-BPD provide information about the neural underpinnings of BPD.


Assuntos
Transtorno da Personalidade Borderline/fisiopatologia , Encéfalo/diagnóstico por imagem , Tomografia por Emissão de Pósitrons , Adulto , Transtorno da Personalidade Borderline/diagnóstico , Transtorno da Personalidade Borderline/diagnóstico por imagem , Encéfalo/metabolismo , Encéfalo/patologia , Mapeamento Encefálico , Feminino , Fluordesoxiglucose F18 , Humanos , Masculino , Escalas de Graduação Psiquiátrica , Adulto Jovem
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