Neonatal outcomes related to maternal SARS-CoV-2 infection in French Guiana: A case-control study.

BACKGROUND: This study aims to assess the neonatal outcomes related to maternal SARS-COV-2 infection. METHODS: In this study, we identified newborns born between May 14 and August 31, 2020, to mothers who were PCR-SRAS-CoV-2 positive at the time of delivery. From the cohort of 974 infants, we performed a nested case-control study. RESULTS: During the study period, 133 (13.7%) mothers were positive for SARS-CoV-2. Among the 35 pregnant women with COVID-19 symptoms (26.3%), cough was the most common symptom, present in half of the cases. Four of them have progressed to critical pneumonia requiring transfer to intensive care unit. The neonates from mothers with positive SARS-CoV-2-RT-PCR, were routinely tested for COVID-19 within the first 24 h after labor, and 3 other newborns tested in the presence of symptoms. There was no significant difference between the two groups with respect to preterm birth, meconium-stained amniotic fluid distress, and neonatal asphyxia. Most infants were breastfed at birth, regardless of their mothers' COVID-19 status. In COVID-19-positive pregnant women admitted to intensive care unit, the proportion of preterm births (OR=12.5 [1.7-90.5]), fetal death in utero (OR=25.9 [2.2-305]) and admission in neonatal intensive care unit admission (OR=13.4 [3.0-60]), appeared higher than the controls. No maternal deaths were recorded. CONCLUSIONS: Our data suggest little neonatal morbidity associated with maternal COVID-19, except for those born to mothers admitted to intensive care unit. However, under breastfeeding conditions with rigorous hygiene precautions and parental education, the risk of transmission of SARS-COV-2 virus to the newborn was very low.

Geohelmintiasis en comunidades indígenas del estado Zulia, Venezuela / Geohelminthiasis in native communities from Zulia State, Venezuela7766TVVBV```9W<<<

Introducción: Las geohelmintiasis son las parasitosis intestinales causadas por helmintos que hacen su ciclo de vida en la tierra y representan un problema de salud público a nivel mundial, que afecta en especial aquellos estratos socioeconómicos más bajos. Objetivo: Determinar la prevalencia de geohelmintos en comunidades indígenas del estado Zulia, Venezuela. Métodos: Se analizaron 250 muestras fecales, de individuos de ambos sexos con edades entre 1 a 80 años. Las muestras fueron procesadas con examen directo, concentrado (Ritchie) y recuento de huevos (Kato-Katz). Resultados: El 35,20 por ciento de los individuos presentaron huevos de geohelmintos en sus heces (88 casos). El grupo etario más afectado fue el de escolares (7-12 años: 38,64 por ciento ), seguido de adultos (20 o más años: 26,13 por ciento ). Ascaris lumbricoides con 25,20 por ciento se encontró en primer lugar, seguido de Trichuris trichiura con 14,80 por ciento , y los menos frecuentes Ancilostomideos con 4,40 por ciento . La mayoría de los individuos presentaron infecciones de intensidad leve (A. lumbricoides 74,60 por ciento , T. trichiura 81,08 por ciento y Ancilostomideos 90,91 por ciento ). Conclusiones: Se detecta una moderada prevalencia de geohelmintos, con un mayor porcentaje de las infecciones de intensidad leve. La presencia de los geohelmintos se relaciona con el escaso saneamiento ambiental que poseen estas comunidades indígenas(AU)

Introduction: Geohelminthiases are intestinal parasitic diseases caused by helminths which complete their life cycle in the soil. They are a global public health problem mainly affecting the lowest socioeconomic strata. Objective: Determine the prevalence of geohelminths in native communities from Zulia State, Venezuela. Methods: Analysis was performed of 250 stool samples from individuals of both sexes aged between 1 and 80 years. The samples were processed by direct examination, concentration (Ritchie) and egg count (Kato-Katz). Results: Geohelminth eggs were found in 35.20 percent of the stool samples studied (88 cases). The most affected age group was schoolchildren (7-12 years: 38.64 percent), followed by adults (20 years and over: 26.13 percent). The most common helminth was Ascaris lumbricoides with 25.20 percent, followed by Trichuris trichiura with 14.80 percent. The least common genus was Ancylostoma with 4.40 percent. Infection was mild in most subjects (A. lumbricoides 74.60 percent, T. trichiura 81.08 percent and Ancylostoma 90.91 percent). Conclusions: A moderate prevalence of geohelminth infection was observed, most of which was mild. The presence of geohelminths is related to poor environmental sanitation in these native communities(AU)