[Translated article] Patient-reported outcome measures for assessing atopic dermatitis in clinical practice.

Atopic dermatitis is a chronic skin condition that affects up to 20% of children and 10% of adults worldwide. Due to the high burden of dermatological signs and symptoms, atopic dermatitis has a significant impact on the quality of life of patients and their families. In the absence of objective measures to accurately assess severity and symptom burden, patient-reported outcome measures are essential to monitor the impact and progression of the disease, as well as the efficacy of treatments. Although there are currently no standardised guidelines for their use in clinical practice, there are some initiatives, such as the Harmonise Outcome Measures for Eczema and Vivir con Dermatitis Atópica, that can provide guidance. As healthcare systems move toward value-based healthcare models, patient-reported measures are becoming increasingly important for incorporating the patient perspective and improving the quality of healthcare services. The use of these measures can help monitor disease activity and guide treatment decisions. This article discusses the impact of atopic dermatitis and describes the patient-reported outcome measures commonly used in atopic dermatitis and the recommendations of the initiatives that have selected a core set of measures to best assess atopic dermatitis in clinical practice. Considering the recommendations of these initiatives and based on our experience in clinical practice, we propose the use of the Dermatology Life Quality Index to assess the impact of the disease on quality of life, the Patient-Oriented Eczema Measure to assess symptom severity, and the Numerical Rating Scale or the Visual Analogue Scale to measure itch intensity. To systematise the administration of these measures and to integrate them into hospital information systems and medical records, we emphasise the importance of telemedicine platforms that allow the electronic administration of these instruments.

Consensus document for the kangaroo mother care method.

INTRODUCTION: Currently, kangaroo mother care (KMC) is an intervention whose implementation in clinical practice varies widely. The aim of this document is to gather the latest evidence-based recommendations in an attempt to reduce interprofessional variation and increase the quality of neonatal care. METHODS: The document was developed following the guidelines provided in the Methodological Manual for the Development of Clinical Practice Guidelines of the National Health System: formulation and prioritization of clinical questions, literature search, critical reading, development of the document and external review. The target population was preterm (PT) and/or low birth weight (LBW) newborn infants admitted to a neonatal unit. RECOMMENDATIONS: Based on the current evidence, recommendations have been issued to address 18 clinical questions regarding the impact of KMC (morbidity and mortality, physiological stability, neurodevelopment, feeding, pain, families), including infants with vascular access or respiratory support devices. It also describes the KMC procedure (transfer, positioning), the facilitators and barriers related to the implementation of KMC and how to implement KMC in extremely preterm newborns (less than 28 weeks of postmenstrual age in the first days of life). CONCLUSIONS: Kangaroo mother care is a beneficial practice for PT infants, LBW infants and their families. The implementation of these recommendations may be useful in everyday clinical practice and may improve KMC outcomes and the quality of care provided to neonatal patients.

Conjunto de recomendaciones nutricionales para desarrollar estrategias dietéticas en atletas

Este estudio partió de una caracterización nutricional en atletas, atendidos desde el punto de vista académico y científico por la Universidad Técnica "Luis Vargas Torres", de Ecuador. Llamó la atención a entrenadores y profesores de este centro pedagógico deportivo que, a pesar de contar con las condiciones básicas adecuadas para la práctica del deporte, se mostraron resultados deportivos desfavorables. Entre los datos recogidos en el estudio exploratorio (encuesta a entrenadores y entrevista a directivos y profesores) se destacó el insuficiente régimen dietético nutricional recibido por los deportistas. Se planteó como objetivo proponer un conjunto de recomendaciones nutricionales que permita perfeccionar las estrategias dietéticas que necesitan los atletas para mantenerse en un estado óptimo en su práctica deportiva y su salud. El diagnóstico, se sustentó en la medición y análisis estadísticos como la correlación de intensidad (Sprints) e ingesta de carbohidratos y la correlación intensidad e ingesta de proteínas. Después de analizar los resultados, se diseñaron y establecieron un grupo de recomendaciones dietéticas enfocadas en mejorar la situación formativa deportiva. Se sugiere que futuras investigaciones profundicen en esta área, para validar y mejorar el marco analítico propuesto.

Este estudo partiu de uma caracterização nutricional em atletas, atendida do ponto de vista acadêmico e científico pela Universidade Técnica "Luis Vargas Torres", do Equador. Chamou a atenção dos treinadores e professores deste centro pedagógico desportivo que, apesar de apresentarem as condições básicas adequadas à prática desportiva, apresentavam resultados desportivos desfavoráveis. Dentre os dados coletados no estudo exploratório (pesquisa com treinadores e entrevistas com dirigentes e professores), destacou-se o insuficiente regime alimentar nutricional recebido pelos atletas. O objetivo foi propor um conjunto de recomendações nutricionais que permitissem aperfeiçoar as estratégias alimentares que os atletas necessitam para se manterem num estado óptimo na sua prática desportiva e saúde. O diagnóstico foi baseado em medidas e análises estatísticas como a correlação de intensidade (Sprints) e ingestão de carboidratos e a correlação de intensidade e ingestão de proteínas. Após a análise dos resultados, foi desenhado e estabelecido um conjunto de recomendações dietéticas focadas na melhoria da situação do treino desportivo. Sugere-se que pesquisas futuras se aprofundem nesta área, para validar e aprimorar o arcabouço analítico proposto.

This study is based on a nutritional characterization of athletes, attended from an academic and scientific point of view by the Luis Vargas Torres Technical University, of Ecuador. It draws the attention of coaches and teachers of this sports pedagogical center that, despite having the appropriate basic conditions for the practice of sports, unfavorable sports results are shown. Among the data collected in the exploratory study (survey of coaches and interviews with managers and teachers), the insufficient nutritional dietary regimen received by athletes was highlighted. The objective was to propose a set of nutritional recommendations that allow perfecting the dietary strategies that athletes need to remain in an optimal state in their sports practice and health. The diagnosis was based on measurement and statistical analysis such as the correlation of intensity (Sprints) and carbohydrate intake and the correlation of intensity and protein intake. After analyzing the results, a group of dietary recommendations focused on improving the sports training situation are designed and established. It is suggested that future research delve into this area, to validate and improve the proposed analytical framework.

Management, development and methodology of the Clinical Practice Guidelines and Recommendations of the Spanish Society of Rheumatology.

The Spanish Society of Rheumatology (SER) brings together the majority of Spain's rheumatologists and, among the many services it offers its members, has a Research Unit (RU). This unit provides methodological support to SER members in clinical and epidemiological research, coordinates and carries out research projects, designs and maintains large patient databases, develops qualitative research projects and produces evidence-based medicine (EBM) documents. Through this last activity, the RU of the SER produces clinical practice guidelines and recommendation documents on topics relevant to rheumatology that meet the most demanding methodological standards. The aim of this article is to describe the management process and methodology followed by the UI of the SER to identify the topics of its EBM documents and how it executes and develops its guidelines and recommendations.

Position paper on perioperative management and surgical risk in the patient with cirrhosis.

INTRODUCTION: Management of the patient with cirrhosis of the liver that requires surgical treatment has been relatively unexplored. In Mexico, there is currently no formal stance or expert recommendations to guide clinical decision-making in this context. AIMS: The present position paper reviews the existing evidence on risks, prognoses, precautions, special care, and specific management or procedures for patients with cirrhosis that require surgical interventions or invasive procedures. Our aim is to provide recommendations by an expert panel, based on the best published evidence, and consequently ensure timely, quality, efficient, and low-risk care for this specific group of patients. RESULTS: Twenty-seven recommendations were developed that address preoperative considerations, intraoperative settings, and postoperative follow-up and care. CONCLUSIONS: The assessment and care of patients with cirrhosis that require major surgical or invasive procedures should be overseen by a multidisciplinary team that includes the anesthesiologist, hepatologist, gastroenterologist, and clinical nutritionist. With respect to decompensated patients, a nephrology specialist may be required, given that kidney function is also a parameter involved in the prognosis of these patients.

[Translated article] Improvements in the Management of Patients With Generalized Pustular Psoriasis in Spain: Recommendations From a Group of Experts.

This consensus document analyzed the management and emotional journey of patients with GPP (generalized pustular psoriasis), and the desirable course of the disease while detecting critical points and translating them into needs and recommendations. This project was conducted in 3 phases with participation from an advisory committee (n=8), an expert panel (n=15) and patients with GPP (n=6). The patients' disease progression was heterogeneous due to disease variations, different health care models implemented and available resources, and the lack of diagnostic and treatment guidelines. A total of 45 different recommendations have been made to optimize management and address the emotional component of these patients. Five of them stand out for their impact and viability. Therefore, a roadmap of priorities has been made generally available to improve the management of patients with GPP.

Consensus update on the therapeutic approach to patients with neurogenic detrusor overactivity.

INTRODUCTION AND OBJECTIVES: A Consensus document on the management of patients with neurogenic detrusor overactivity (NDO) was published in 2018. The present document aims to update its recommendations regarding treatment considering the new evidence available, and to contribute to the standardization of the management of this disorder. METHODS: The methodology used was based on a systematic review and the Nominal Group Technique. The clinical coordinator (CC) and the Consensus update group (CUG) defined the questions to be updated and carried out a systematic review to identify the new available evidence. After being evaluated by the expert panel, the relevant recommendations were updated and agreed in a consensus meeting. RESULTS: A total of 3210 publications were identified and 26 publications that met the inclusion criteria were included. The CUG updated 18 recommendations on the therapeutic approach to NDO. Unanimous consensus was reached on all of them. CONCLUSIONS: Previous recommendations need to be revised due to the availability of new drugs, the increasing evidence on the use of botulinum toxin or neuromodulation procedures, and new surgical options.

Patient-reported outcome measures for assessing atopic dermatitis in clinical practice. / Medidas de resultados comunicados por el paciente para evaluar la dermatitis atópica.

Atopic dermatitis is a chronic skin condition that affects up to 20% of children and 10% of adults worldwide. Due to the high burden of dermatological signs and symptoms, atopic dermatitis has a significant impact on the quality of life of patients and their families. In the absence of objective measures to accurately assess severity and symptom burden, patient-reported outcome measures are essential to monitor the impact and progression of the disease, as well as the efficacy of treatments. Although there are currently no standardised guidelines for their use in clinical practice, there are some initiatives, such as the Harmonise Outcome Measures for Eczema and Vivir con Dermatitis Atópica, that can provide guidance. As healthcare systems move towards value-based healthcare models, patient-reported measures are becoming increasingly important for incorporating the patient perspective and improving the quality of healthcare services. The use of these measures can help monitor disease activity and guide treatment decisions. This article discusses the impact of atopic dermatitis and describes the patient-reported outcome measures commonly used in atopic dermatitis and the recommendations of the initiatives that have selected a core set of measures to best assess atopic dermatitis in clinical practice. Considering the recommendations of these initiatives and based on our experience in clinical practice, we propose the use of the Dermatology Life Quality Index to assess the impact of the disease on quality of life, the Patient-Oriented Eczema Measure to assess symptom severity, and the Numerical Rating Scale or the Visual Analogue Scale to measure itch intensity. To systematize the administration of these measures and to integrate them into hospital information systems and medical records, we emphasise the importance of telemedicine platforms that allow the electronic administration of these instruments.

Recomendaciones para el uso de antimicrobianos en personas adultas hospitalizadas en el Sistema Nacional Integrado de Salud / Recommendations for the use of antimicrobials in adults hospitalized in the National Integrated Health System

El presente documento contiene un conjunto de recomendaciones necesarias para la estandarización de los procesos de atención en salud, para contribuir a la mejora continua de la calidad de atención. Su proceso de elaboración ha incluido la búsqueda bibliográfica de información científica, el análisis y adaptación local de acuerdo a los medicamentos establecidos en el Listado institucional de medicamentos esenciales del Ministerio de Salud y los datos del Cubo Microbiológico del último año, así mismo se ha desarrollado el análisis y discusión de los hallazgos, por parte del equipo técnico involucrado en el proceso de atención a nivel nacional, proporcionando un instrumento útil para la optimización del uso de antimicrobianos, la toma de decisiones para mejorar la calidad de uso de estos, mejorando su eficacia, reduciendo sus efectos adversos, la diseminación de resistencias y conseguir un uso eficiente de los mismos; sin que esto signifique sustituir al mejor criterio médico individua

This document contains a set of recommendations necessary for the standardization of health care processes, to contribute to the continuous improvement of the quality of care. Its preparation process has included a bibliographic search for scientific information, analysis and local adaptation according to the medications established in the institutional List of essential medications of the Ministry of Health and the data from the Microbiological Cube of the last year, and it has also been developed the analysis and discussion of the findings, by the technical team involved in the care process at the national level, providing a useful instrument for optimizing the use of antimicrobials, decision making to improve the quality of their use, improving their effectiveness, reducing their adverse effects, the spread of resistance and achieving efficient use of them; without this meaning replacing the best individual medical judgment

Recomendaciones médicas desde atención primaria sobre ejercicio físico en el posparto / Medical recommendations from primary care on physical exercise in the postpartum

Existe evidencia que demuestra los beneficios de la práctica de actividad física (AF)/ejercicio para la madre después del parto. Sin embargo, este periodo posparto (PP) es, a menudo, una oportunidad perdida en el curso de la vida de las mujeres, para comenzar o reanudar la práctica de ejercicio físico, y obtener los grandes beneficios que esto les puede reportar. El objetivo de este artículo fue analizar los beneficios del ejercicio durante el PP; la prescripción de AF; las recomendaciones sobre el momento de reanudar su práctica; las barreras y facilitadores; el ejercicio físico realizado durante la lactancia materna; así como su papel en las enfermedades y molestias más frecuentes en este periodo, teniendo siempre presente que la labor del médico de atención primaria resulta fundamental para motivar y alentar a las mujeres para que lo practiquen después del parto. (AU)

There is evidence that demonstrates the benefits of practicing physical activity/exercise for the mother after childbirth. However, this postpartum period (PP) is often a missed opportunity in a lifetime for women to start or resume physical exercise and get the great benefits that it can bring them. The objective of this article was to analyze the benefits of physical exercise during PP; the prescription of physical exercise; recommendations on when to resume your practice; barriers and facilitators; physical exercise during breastfeeding; as well as its role in the most frequent illnesses and discomforts in this period, always keeping in mind that the work of the primary care doctor is essential to motivate and encourage women to perform physical exercise in the PP. (AU)

Recomendaciones de alimentación para primera infancia de 0 a 7 años / Feeding recommendations for early childhood from 0 to 7 years

El propósito de este documento es mejorar las prácticas adecuadas de alimentación perceptiva como elemento clave del enfoque Cuidado Cariñoso y Sensible, que involucra la reciprocidad entre la niña o el niño y la persona que lo alimenta, que además incorpora la atención en salud, oportunidades del aprendizaje temprano, la protección social de la infancia, entre otros y retoma las recomendaciones de alimentación de la Estrategia Mundial del Fondo de las Naciones Unidas para la Infancia (UNICEF) y la Organización Mundial de la Salud (OMS) sobre alimentación del lactante y niño pequeño, en la cual se establece que las prácticas adecuadas de lactancia materna y alimentación, juegan un pilar fundamental en el estado nutricional, la salud, el crecimiento y el desarrollo exitoso de las niñas y los niños

The purpose of this document is to improve appropriate responsive feeding practices as a key element of the Loving and Sensitive Care approach, which involves reciprocity between the child and the person who feeds him or her, which also incorporates health care, opportunities for early learning, social protection of children, among others, and takes up the feeding recommendations of the Global Strategy of the United Nations Children's Fund (UNICEF) and the World Health Organization (WHO) on infant and child feeding. small, which establishes that adequate breastfeeding and feeding practices play a fundamental pillar in the nutritional status, health, growth and successful development of girls and boys

Considerazioni etico-giuridiche sui criteri di priorità di cura per i pazienti in terapia intensiva durante la pandemia di COVID-19 / Consideracions ètic-jurídiques sobre els criteris de prioritat de cura pels pacients en teràpia intensiva durant la pandèmia de la COVID-19 / Consideraciones ético-jurídicas sobre los criterios de prioridad de atención para los pacientes en terapia intensiva durante la pandemia de COVID-19 / Ethical-legal considerations on priority care criteria for patients in intensive therapy during the COVID-19 pandemic

Ci si è chiesti se la pandemia abbia modificato il modo in cui la morte e il morire vengano pensati. L’incontrollata diffusione del contagio e la mancanza di un’adeguata risposta organizzativa in termini di sanità pubblica ha determinato ben presto nelle TI una sproporzione tra domanda di assistenza (insufficienza respiratoria acuta) e risorse disponibili (personale formato, posti-letto, ventilatori meccanici). I clinici si sono così trovati nella condizione di dover decidere quali pazienti ammettere in TI e quali escludere. Sia in Italia che in Spagna si è fatto ricorso al triage: sono state elaborate alcune raccomandazioni che hanno destato perplessità e critiche nell’ambito medico ed etico-giuridico.(AU)

En aquest article es reflexiona sobre la forma en què la pandèmia derivada de la COVID-19 ha alterat determinats processos assistencials davant de la mort. La ràpida propagació incontrolada de la malaltia i la manca de resposta organitzativa en termes de salut pública aviat van conduir a una desproporció entre la demanda assistencial en cures intensives i els recursos humans imaterials per satisfer-la. En ocasions, els metges s'han vist en el dilema de decidir quins pacients tractar i quins excloure a les unitats de cures intensives. Tant a Espanya com a Itàlia s'ha fet servir el triatge i s'han publicat algunes recomanacions que han suscitat algunes crítiques en l'àmbit mèdic, ètic i legal. Es planteja el dubte de si aquestes mesures excepcionals es poden aplicar quan es recupera la normalitat sociosanitària.(AU)

En este artículo se reflexiona sobre la forma en que la pandemia derivada del COVID-19 ha alterado determinados procesos asistenciales frente a la muerte. La rápida propagación incontrolada de la enfermedad y la faltade respuesta organizativa en términos de salud pública pronto condujeron a una desproporción entre la demanda asistencial en cuidados intensivos y los recursos humanos y materiales para satisfacerla. En ocasiones, los médicos se han visto en el dilema de decidir qué pacientes tratar y cuales excluir en las unidades de cuidados intensivos. Tanto en España como en Italia se ha usado el triaje y se han publicado algunas recomendaciones que han suscitado ciertas críticas en el ámbito médico, ético y legal. Se plantea el interrogante de que estas medidas excepcionales se puedan aplicar cuando se recupera la normalidad socio sanitaria.(AU)

This paper reflects on the way in which the pandemic derived from COVID-19 has altered certain care processes in the face of death. The rapid uncontrolled spread of the disease, and the lack of organizational response in terms of public health soon led to a disproportion between the demand for intensive care and the human and material resources to meet it. At times, doctors have been faced with the dilemma of deciding which patients to treat and which to exclude in intensive care units. Both in Spain and Italy triage has been used and some recommendations have been published that have provoked some criticism in the medical, ethical and legal field. The question arises whether these exceptional measures can be applied when socio-sanitary normality is restored.(AU)

Documento de consenso de la Sociedad Española de Neurología sobre el tratamiento de la esclerosis múltiple y manejo holístico del paciente 2023 / Consensus statement of the Spanish Society of Neurology on the treatment of multiple sclerosis and holistic patient management in 2023

El último documento de consenso del Grupo de Estudio de Enfermedades Desmielinizantes de la Sociedad Española de Neurología sobre el tratamiento de la esclerosis múltiple (EM) data del año 2016. Aunque muchas consideraciones continúan todavía vigentes, desde entonces se han producido cambios significativos en el manejo y tratamiento de esta enfermedad, motivados no solo por la aprobación de nuevos fármacos con diferentes mecanismos de acción, sino también por la evolución de conceptos otrora consolidados. Esto ha permitido abordar situaciones especiales como el embarazo y la vacunación desde otra perspectiva, e incluir nuevas variables en la toma de decisiones en práctica clínica, como plantear tratamiento modificador de la enfermedad (TME) de alta eficacia en fases tempranas, considerar la perspectiva del paciente y utilizar nuevas tecnologías como monitorización remota. Estos cambios han motivado la presente actualización del consenso mediante metodología Delphi, con el objetivo de reflejar el nuevo paradigma de manejo del paciente con EM basándose en la evidencia científica y la experiencia clínica de los participantes. Entre las principales conclusiones destacan como recomendaciones: iniciar TME inmunomodulador en el síndrome radiológico aislado con actividad radiológica persistente, evaluar la perspectiva del paciente y abandonar la terminología «líneas de tratamiento» en la clasificación de los TME (consenso mayor del 90%). Tras el diagnóstico de EM la elección del primer TME debería considerar la presencia/ausencia de factores de mal pronóstico (epidemiológicos, clínicos, radiológicos y biomarcadores) para la aparición de nuevos brotes o progresión de discapacidad, pudiendo plantear desde el inicio TME de alta eficacia. (AU)

The last consensus statement of the Spanish Society of Neurology's Demyelinating Diseases Study Group on the treatment of multiple sclerosis (MS) was issued in 2016. Although many of the positions taken remain valid, there have been significant changes in the management and treatment of MS, both due to the approval of new drugs with different action mechanisms and due to the evolution of previously fixed concepts. This has enabled new approaches to specific situations such as pregnancy and vaccination, and the inclusion of new variables in clinical decision-making, such as the early use of high-efficacy disease-modifying therapies (DMT), consideration of the patient's perspective, and the use of such novel technologies as remote monitoring. In the light of these changes, this updated consensus statement, developed according to the Delphi method, seeks to reflect the new paradigm in the management of patients with MS, based on the available scientific evidence and the clinical expertise of the participants. The most significant recommendations are that immunomodulatory DMT be started in patients with radiologically isolated syndrome with persistent radiological activity, that patient perspectives be considered, and that the term “lines of therapy” no longer be used in the classification of DMTs (> 90% consensus). Following diagnosis of MS, the first DMT should be selected according to the presence/absence of factors of poor prognosis (whether epidemiological, clinical, radiological, or biomarkers) for the occurrence of new relapses or progression of disability; high-efficacy DMTs may be considered from disease onset. (AU)

XEN® 45 en el manejo quirúrgico del glaucoma en fases tempranas: estudio nacional de consenso según metodología Delphi / XEN-45 in the management of Early Glaucoma Surgery: A National Delphi Consensus Study

Antecedentes y objetivo: Las recomendaciones sobre el manejo general del glaucoma y el uso de cirugías mínimamente-invasivas y microincisionales en fases tempranas son limitadas. El objetivo de este estudio fue establecer un consenso sobre el manejo del glaucoma, centrándose en el implante XEN 45 (AbbVie Inc., North Chicago, IL, EE. UU.). Métodos: Se utilizó un método Delphi. El comité científico dirigió el estudio, identificó el panel de expertos y participó en la elaboración del cuestionario. Se invitó a 51 expertos a completar, en una escala Likert de 9 puntos, un cuestionario de 89 ítems que cubría 3 bloques temáticos. Se realizaron 2 rondas Delphi. Se logró consenso si≥66,6% de los expertos llegaron a un acuerdo o desacuerdo. Resultados: Los panelistas acordaron 84 ítems relacionados con la calidad de vida, el algoritmo terapéutico y el perfil del paciente, y el manejo quirúrgico pre y postoperatorio. Los panelistas consideraron el implante XEN idóneo para tratar el glaucoma en diferentes etapas y para diferentes perfiles de pacientes: pacientes jóvenes/ancianos/con comorbilidades-significativas, glaucoma-miópico, pacientes con fracaso quirúrgico previo y con postoperatorio complejo. El implante XEN se consideró un paso terapéutico previo a la cirugía filtrante clásica y una posible primera opción quirúrgica en pacientes ancianos con comorbilidades y presión intraocular descontrolada. El implante XEN permite al paciente retomar sus actividades diarias más rápidamente que las cirugías filtrantes convencionales y reducir y/o eliminar los tratamientos tópicos. Conclusiones: Este consenso según la metodología Delphi proporcionó una serie de recomendaciones generales para el tratamiento del glaucoma, incluidas aquellas relacionadas con la calidad de vida del paciente, el algoritmo terapéutico y el perfil del paciente, y específicas con respecto al uso del implante XEN.(AU)

Background and objective: Recommendations on general glaucoma management and the use of early minimally invasive and microincisional surgeries are limited. This study aimed to establish consensus regarding glaucoma management, focusing on the XEN-45 gel stent implant. Methods: A Delphi consensus-driven process was used. The scientific committee led the study, identified the expert panel, and participated in elaborating the questionnaire. Fifty-one panelists were invited to complete, on a nine-point Likert scale, an 89-item questionnaire covering three topic blocks. Two Delphi rounds were performed. Consensus was achieved if ≥66.6% of panelists reached agreement or disagreement. Results: Panelists agreed on 84 items related to the patients’ quality of life, the therapeutic algorithm and patient profile, and surgical and pre- and post-operative management. Panelists agreed on the suitability of XEN stent implants to treat glaucoma at different stages and for different patient profiles: young patients, elderly or with significant comorbidities, and with myopic glaucoma, patients who failed previous surgeries, and with previous poor post-operative experience. XEN surgery was considered a therapeutic step prior to classic filtering surgery and a possible first surgical option in elderly patients with comorbidities and uncontrolled intraocular pressure. XEN surgery allows the patient to return to routine daily activities faster than conventional filtering surgeries and to reduce and/or eliminate topical treatments. Conclusions: This Delphi-driven consensus resulted in a series of general recommendations for glaucoma management, including those related to patient quality of life, therapeutic algorithm, and patient profile, and specific ones regarding the use of XEN stent gel surgery.(AU)

Recommendations for the future management of thrombocytopenia in patients with liver cirrhosis: A modified RAND/UCLA appropriateness method / Recomendaciones para el futuro manejo de la trombocitopenia en pacientes con cirrosis hepática: una versión modificada de la Metodología RAND/UCLA

Objective The lack of consensus and specific guidelines, and the introduction of new treatments in thrombocytopenia management in liver cirrhosis patients, required a series of recommendations by experts to improve knowledge on this disease. This study's aim was to improve the knowledge around thrombocytopenia in liver cirrhosis patients, in order to contribute to the generation of future evidence to improve the management of this disease. Patients and methods A modified version of the RAND/UCLA appropriateness method was used. The scientific committee, a multidisciplinary team of 7 experts in managing thrombocytopenia in liver cirrhosis patients, identified the expert panel, and participated in elaborating the questionnaire. Thirty experts from different Spanish institutions were invited to answer a 48-item questionnaire covering 6 areas on a nine-point Likert scale. Two rounds were voted. The consensus was obtained if >77.7% of panelists reached agreement or disagreement. Results A total of 48 statements were developed by the scientific committee and then voted by the experts, resulting in 28 defined as appropriate and completely necessary, relating to evidence generation (10), care circuit, (8), hemorrhagic risk assessment, decision-making and diagnostic tests (14), professionals’ role and multidisciplinary coordination (9) and patient education (7). Conclusions This is the first consensus in Spain on the management of thrombocytopenia in liver cirrhosis patients. Experts indicated several recommendations to be carried out in different areas that could help physicians make better decisions in their clinical practice (AU)

Objetivo La falta de consenso y guías específicas, y la introducción de nuevos tratamientos para el manejo de la trombocitopenia en pacientes con cirrosis hepática, requerían recomendaciones expertas para mejorar el conocimiento sobre dicha patología. El objetivo de este estudio es mejorar el conocimiento sobre la trombocitopenia en pacientes con cirrosis hepática de cara a contribuir en la generación de futuras evidencias que mejoren el manejo de esta patología. Metodología Ae utilizó una versión modificada de la metodología Delphi RAND/UCLA. El comité científico, formado por 7 expertos en el manejo de la trombocitopenia en pacientes con cirrosis hepática, identificó un panel de expertos y participó en la elaboración del cuestionario de recomendaciones. Treinta expertos de diferentes hospitales españoles fueron invitados a responder al cuestionario. Los expertos respondieron a 48 ítems divididos en 6 áreas en una escala Likert de 9 puntos. La votación tuvo lugar en 2 rondas, en las que se obtuvo consenso siempre y cuando >77,7% de los panelistas alcanzasen acuerdo o desacuerdo. Resultados Cuarenta y ocho recomendaciones fueron elaboradas por el comité científico para su votación por parte del panel de expertos. Finalmente 28 recomendaciones fueron consideradas apropiadas y completamente necesarias: 10 de ellas relativas a la generación de evidencia; 8 al circuito de cuidados; 14 a la evaluación de riesgo hemorrágico, la toma de decisiones y los test diagnósticos; 9 al papel de los profesionales y la coordinación multidisciplinar, y 7 a la educación de los pacientes. Conclusiones Se trata del primer consenso español en el manejo de la trombocitopenia en pacientes con cirrosis hepática. Los expertos definieron un amplio número de recomendaciones que podrían contribuir a la toma de decisiones clínicas y a la mejora en el manejo de estos pacientes en la práctica clínica real (AU)

Consensus statement of the Spanish Society of Neurology on the treatment of multiple sclerosis and holistic patient management in 2023.

The last consensus statement of the Spanish Society of Neurology's Demyelinating Diseases Study Group on the treatment of multiple sclerosis (MS) was issued in 2016. Although many of the positions taken remain valid, there have been significant changes in the management and treatment of MS, both due to the approval of new drugs with different action mechanisms and due to the evolution of previously fixed concepts. This has enabled new approaches to specific situations such as pregnancy and vaccination, and the inclusion of new variables in clinical decision-making, such as the early use of high-efficacy disease-modifying therapies (DMT), consideration of the patient's perspective, and the use of such novel technologies as remote monitoring. In the light of these changes, this updated consensus statement, developed according to the Delphi method, seeks to reflect the new paradigm in the management of patients with MS, based on the available scientific evidence and the clinical expertise of the participants. The most significant recommendations are that immunomodulatory DMT be started in patients with radiologically isolated syndrome with persistent radiological activity, that patient perspectives be considered, and that the term "lines of therapy" no longer be used in the classification of DMTs (> 90% consensus). Following diagnosis of MS, the first DMT should be selected according to the presence/absence of factors of poor prognosis (whether epidemiological, clinical, radiological, or biomarkers) for the occurrence of new relapses or progression of disability; high-efficacy DMTs may be considered from disease onset.

XEN-45 in the management of early glaucoma surgery: A national Delphi consensus study.

BACKGROUND AND OBJECTIVE: Recommendations on general glaucoma management and the use of early minimally invasive and microincisional surgeries are limited. This study aimed to establish consensus regarding glaucoma management, focusing on the XEN-45 gel stent implant. METHODS: A Delphi consensus-driven process was used. The scientific committee led the study, identified the expert panel, and participated in elaborating the questionnaire. Fifty-one panelists were invited to complete, on a nine-point Likert scale, an 89-item questionnaire covering three topic blocks. Two Delphi rounds were performed. Consensus was achieved if ≥66.6% of panelists reached agreement or disagreement. RESULTS: Panelists agreed on 84 items related to the patients' quality of life, the therapeutic algorithm and patient profile, and surgical and pre- and post-operative management. Panelists agreed on the suitability of XEN stent implants to treat glaucoma at different stages and for different patient profiles: young patients, elderly or with significant comorbidities, and with myopic glaucoma, patients who failed previous surgeries, and with previous poor post-operative experience. XEN surgery was considered a therapeutic step prior to classic filtering surgery and a possible first surgical option in elderly patients with comorbidities and uncontrolled intraocular pressure. XEN surgery allows the patient to return to routine daily activities faster than conventional filtering surgeries and to reduce and/or eliminate topical treatments. CONCLUSIONS: This Delphi-driven consensus resulted in a series of general recommendations for glaucoma management, including those related to patient quality of life, therapeutic algorithm, and patient profile, and specific ones regarding the use of XEN stent gel surgery.

Recomendación De Actividad Física A Pacientes Con Trastorno De Salud Mental Por Los Profesionales De Atención Primaria De Salud Y Variables Asociadas A La Cumplimentación De Las Recomendaciones Estudio Transversal / Recommendation of Physical Activity to Patients with Mental Health Disorders by Primary Health Care Professionals and Variables Associated with Compliance with Recommendations Cross-sectional Study

Introducción: Fomentar la recomendación de activos para la salud junto a "factores de estilo de vida" como la actividad física, han mostrado sus efectos beneficiosos sobre la salud mental. Objetivo: Estimar la cumplimentación de la prescripción de actividad física en pacientes diagnosticados de enfermedad mental. Metodología: Estudio descriptivo transversal mediante encuesta. 215 participantes. Se recogieron variables sociodemográficas, de salud y se elaboró un cuestionario ad hoc sobre la realización de ejercicio físico. Con el estadístico chi-cuadrado se analizó la relación de la recomendación de AF y las características sociodemográficas, de salud y las variables del médico/a de familia, para la correlación entre tiempo invertido en la realización de AF y percepción de estado de salud se utilizó el estadístico Rho de Spearman. Se realizó una regresión logística multivariante, cuya variable dependiente fue la recomendación de AF. Resultados: Variables significativas que predicen que se les prescriba AF son ser mujer y que el médico/a de familia tenga 50 años o menos. No hay una relación significativa entre la recomendación por un profesional sanitario y realizar AF (pvalor=0,058). Existe una correlación directa significativa entre el tiempo de dedicación a realizar AF y la percepción de su estado de salud (Rho de Spearman= 0,780; pvalor=0,039). Discusión: La AF mejora el bienestar y la salud mental pero prescribirla requiere habilidad clínica y formación. Sería necesario el apoyo de un especialista en ejercicio o promoción de la actividad física como parte de un enfoque multidisciplinario para la atención de la salud mental.(AU)

[Medical recommendations from primary care on physical exercise in the postpartum]. / Recomendaciones médicas desde atención primaria sobre ejercicio físico en el posparto.

There is evidence that demonstrates the benefits of practicing physical activity/exercise for the mother after childbirth. However, this postpartum period (PP) is often a missed opportunity in a lifetime for women to start or resume physical exercise and get the great benefits that it can bring them. The objective of this article was to analyze the benefits of physical exercise during PP; the prescription of physical exercise; recommendations on when to resume your practice; barriers and facilitators; physical exercise during breastfeeding; as well as its role in the most frequent illnesses and discomforts in this period, always keeping in mind that the work of the primary care doctor is essential to motivate and encourage women to perform physical exercise in the PP.