Experiencias de la sexualidad de mujeres diagnosticadas con cáncer ginecológico: una aproximación desde la teoría de los holones / Experiences of sexuality of women diagnosed with gynecological cancer: a holon theory approach

Resumen La investigación tuvo como objetivo comprender las experiencias alrededor de la sexualidad desde la teoría de los holones en un grupo de mujeres diagnosticadas con cáncer ginecológico en la ciudad de Pereira, Colombia. Se implementó un diseño cualitativo y fenomenológico, con la participación de seis mujeres entre 30 y 60 años, a quienes se aplicaron entrevistas semiestructuradas explorando los holones de reproductividad, género, erotismo y vinculación afectiva interpersonal. Las entrevistas fueron transcritas y analizadas de forma manual, mediante codificación abierta y axial para identificar categorías emergentes. En los discursos de las mujeres se evidenciaron elementos relacionados a los holones de la sexualidad. En el holón de reproductividad, se encontró una resignificación del rol reproductivo como madres; en el holón de género, se presentaron actitudes positivas hacia el cuerpo y amenazas a la identidad de género por causa de los cambios provocados por la enfermedad; en el holón de erotismo, las mujeres relataron experiencias sexuales marcadas por el dolor y el apoyo erótico de la pareja; y en el holón de vinculación afectiva interpersonal, se evidenciaron situaciones de estabilidad conyugal, separación temporal con la pareja y sostenimiento de vínculos abusivos durante el proceso de tratamiento oncológico. Estos hallazgos muestran una amplia reconfiguración integral de la sexualidad femenina en cada uno de los holones y realizan un aporte significativo a la comprensión de las subjetividades de las mujeres en el proceso de afrontar el cáncer ginecológico. Se recomienda realizar nuevas investigaciones con mayor cantidad de participantes y en otras regiones de Colombia.

Abstract The research aimed to understand the experiences around sexuality, from the holon theory, in a group of women diagnosed with gynecological cancer from Pereira, Colombia. A qualitative and phenomenological design was carried out, with the participation of six women between 30 and 60 years of age, to whom semi-structured interviews were applied, exploring the holons of reproductivity, gender, eroticism and interpersonal affective bonding. The interviews were transcribed and analyzed manually, using open and axial coding to identify emerging categories. In the women's discourses, elements related to the holons of sexuality were evident. In the holon of reproductivity, a resignification of the reproductive role as mothers was found; in the holon of gender, positive attitudes towards their bodies and threats to gender identity due to the changes caused by the disease were presented; in the holon of eroticism, women reported sexual experiences characterized by pain and erotic support from their partners; and in the holon of affective interpersonal bonding, they reported situations of marital stability, temporary separation from their partners and abusive ties during the process of cancer treatment. These findings show a comprehensive reconfiguration of female sexuality in each of the holons and make a significant contribution to the understanding of women's subjectivities in the process of coping with gynecological cancer. Further research with a larger number of participants and in other regions of Colombia is recommended.

Efeito do tônus do corpo perineal nas disfunçõessexuais em mulheres jovens nulíparas / Effect of perineal body tone on sexual dysfunctionsin young nulliparous women

Objetivo: avaliar o tônus do corpo perineal em mulheres jovens nulíparas e correlacionar com as funções sexuais e a presença de disfunção sexual. Método: foi realizado um estudo descritivo, observacional, transversal utilizando uma amostra de conveniência incluindo mulheres adultas jovens nulíparas. A avaliação das participantes consistiu na aplicação dos questionários socioclínico, Pelvic Organ Prolaps / Urinary Incontinence Sexual Questionnaire (PISQ-12), Female Sexual Function Index (FSFI) e exame físico do tônus do corpo perineal. Os dados foram analisados pelo programa Statistical Package for the Social Sciences (SPSS®), versão 23, adotando um nível de significância de 5%. Resultados: participaram 77 mulheres jovens nulíparas (21,68 ± 2,94 anos), destas 77, 92% apresentavam vida sexual ativa e 66,03% tônus normal do corpo perineal. Dentre as alterações tônicas, o aumento do tônus predominou (33,76%). Houve alta prevalência de disfunção sexual (87,01%) pelo FSFI (23,38 ± 7,21) com maior queixa de dispareunia. Mulheres com tônus aumentado apresentaram maior disfunção sexual em relação a desejo e estímulo subjetivo (p=0,04), à excitação (p=0,01), satisfação (p=0,04) e dor ou a desconforto (p=0,03). Houve correlação inversa entre a presença de aumento do tônus e os domínios FSFI desejo e estímulo subjetivo (R= - 0,56) e excitação (R= - 0,34) e correlação direta para dor ou desconforto (R= 0,30). Conclusão: o aumento do tônus do corpo perineal piora a função sexual de mulheres jovens nulíparas.

Sexual Function Index (FSFI) and physical examination of the tone of the perineal body. The data were analyzed using the Statistical Package for the Social Sciences (SPSS®), version 23, adopting a significance level of 5%. Results: 77 young nulliparous women (21.68 ± 2.94 years) participated, of which 77, 92% had an active sexual life and 66.03% had normal tone of the perineal body. Among the tonic changes, increased tone predominated (33.76%). There was a high prevalence of sexual dysfunction (87.01%) according to the FSFI (23.38 ± 7.21) with greater complaints of dyspareunia. Women with increased tone had greater sexual dysfunction in relation to desire and subjective stimulation (p=0.04), excitement (p=0.01), satisfaction (p=0.04) and pain or discomfort (p=0.03). There was an inverse correlation between the presence of increased tone and the FSFI domains desire and subjective stimulus (R= - 0.56) and excitement (R= - 0.34) and a direct correlation for pain or discomfort (R= 0.30). Conclusion: increased perineal body tone worsens sexual function in young nulliparous women.

The Vaginal Penetration Skills Scale (VPSS): a paradigm shift in genito-pelvic pain/penetration disorder screening, assessment, and stratification.

BACKGROUND: Receptive vaginal penetration skills have been implicated in the etiology, explanatory models, and treatment of genito-pelvic pain penetration disorder (GPPPD). However, there are no psychometric skills measures designed to screen, assess, and stratify GPPPD. AIM: We aimed to develop and psychometrically evaluate a new scale-the Vaginal Penetration Skills Scale (VPSS)-to screen, assess, and stratify GPPPD. METHODS: This study included 148 Brazilian females with GPPPD symptoms (113 lifelong and 35 acquired) and 251 Brazilian females without sexual complaints. We conducted factor analyses considering all participants (n = 399). Then, we conducted latent class analysis within the GPPPD group to identify clusters of individuals with similar VPSS profiles. We assessed convergent validity through intercorrelation with the Brazilian versions of the Female Genital Self-Image Scale (FGSIS) and the 6-item Female Sexual Function Index (FSFI-6). OUTCOMES: We developed complete and short-form versions of the VPSS (VPSS-29 and VPSS-SF11, respectively), each with 3 dimensions, to screen, assess, and stratify GPPPD. RESULTS: Factor analysis yielded a 3-factor VPSS model with the "Nonsexual Genital Self-Exploration," "Nonsexual Vaginal Penetration Skills," and "Sexual Vaginal Penetration Skills" dimensions for both VPSS versions. The reliability was excellent for the VPSS-29 (ω = 0.981, α = 0.981) and the VPSS-SF11 (ω = 0.959, α = 0.961). All 3 dimensions could detect significant differences between patients with GPPPD and healthy females. They also differentiated the patients with GPPPD, distinguishing gradient levels. For convergent validity, we found moderate to strong correlations (rho = 0.715-0.745) between the VPSS, FGSIS, and FSFI-6. CLINICAL IMPLICATIONS: The VPSS can be applied easily in both clinical and research settings. STRENGTHS AND LIMITATIONS: The VPSS provides a concise and thorough evaluation of receptive vaginal penetration skills in both sexual and nonsexual contexts among patients with GPPPD. The sample had limited diversity regarding gender and sexual orientation; therefore, it is important to validate the use of this scale in populations beyond the cisgender heterosexual female population to ensure its applicability in diverse settings. CONCLUSION: These results support the reliability and psychometric validity of the VPSS as a self-report measure to screen, assess, and stratify GPPPD symptoms.

Tailoring Sexual Health Research Practices to Meet the Needs of Adolescent Girls in Low- and Middle-Income Countries: Findings from Mexico.

Sexual and reproductive health (SRH) research is essential for the development of population-tailored evidence-based policies and programs that support sexual health among adolescent girls. However, ethical challenges create barriers to girls' participation in low- and middle-income countries (LMICs). From February to September 2019, girls aged 16-20 (n = 30) who participated in the Jovenes Sanos study in Tijuana, Baja California (ClinicalTrials: NCT03660514) responded to in-depth interviews (IDs) on the perceived risks and benefits of participating in studies which address gender-based violence, unintended pregnancy, and STIs. Emergent themes indicated the need to ensure that consent and incentive procedures are tailored to the developmental level of participants, while highlighting the importance of researcher-participant relationships, and demonstrating how research can serve as an opportunity to empower girls to express their sexual health medical needs. Understanding adolescent girls' voices is a critical step in ensuring that consent to participate SRH research is tailored to the developmental needs of participants, is culturally competent, and has a participant-centered approach.

The impact of COVID-19 on the male reproductive system.

OBJECTIVE: The relevance of the study is determined by the deepening understanding of the global consequences of the coronavirus pandemic, which affect not only lung health but also a wide range of other body systems. In light of new data on the long-term effects of coronavirus infection, this study is highly significant. The purpose of this study is to investigate the impact of coronavirus infection on the male reproductive system and assess its potential influence on male fertility to refine the mechanisms of damage and provide recommendations for medical care. METHODS: The study utilised a combination of methods, including a meta-analysis of medical organisation databases, analysis of clinical cases, representative sample method, and quantitative survey method. These approaches allowed for a comprehensive and multifaceted view of the problem. RESULTS: The samples of sperm showed a noticeable decrease in progressive motility, sperm concentration, and volume, especially in patients with moderate and severe symptoms of COVID-19, whereas patients with mild symptoms only experienced a decrease in progressive motility and overall sperm motility. The survey identified symptoms of male reproductive system dysfunction after recovering from COVID-19. Predominant symptoms included decreased libido (15%), impotence (13%), and infections of the genital organs (12%). Most surveyed men lacked sufficient awareness of other aspects of male reproductive health, including infections, genetic defects, chronic diseases, and available medical services. CONCLUSIONS: As a result of the study, it was concluded that coronavirus infection can have a negative impact on the male reproductive system. The practical value of this study lies in improving approaches to medical care for men who have recovered from COVID-19 and creating preventive programmes.

Experiencias y conocimientos, sobre salud sexual y reproductiva en personas con discapacidad en Ecuador / Experiences and knowledge about sexual and reproductive health of people with disabilities in Ecuador / Experiências e conhecimento sobre saúde sexual e reprodutiva entre pessoas com deficiência no Equador

La discapacidad es una afección (deficiencia) que dificulta el desarrollo de las actividades cotidianas y la interacción del individuo con el entorno que lo rodea, se divide en: discapacidad física, motora, orgánica, mental, intelectual y sensorial. Objetivo: Documentar las percepciones y emociones en salud sexual y reproductiva de las personas con discapacidad del Centro diurno del Cantón Biblián. Metodología: Se trata de un estudio observacional cualitativo en el que se recopila las vivencias de 34 personas de la población con discapacidad que forman parte del Proyecto Centro diurno "San José" de Biblián, siendo seleccionados cinco participantes mediante muestreo simple no probabilístico. Hallazgos: A partir del análisis de los relatos se determina que las personas con discapacidad mantienen relaciones satisfactorias aún con las inseguridades que los rodean. Sin embargo, la exclusión dentro de sus propios hogares, la escasa información segura y la difusión mediática masiva sobre la sexualidad han condicionado percepciones que los expone a un nivel elevado de vulnerabilidad. A manera de Conclusión: En varias ocasiones existen prejuicios y tabúes al hablar de sexualidad con personas con discapacidad en los diferentes hogares, los familiares optan por no responder interrogantes relacionadas, por eso el personal de salud cumple un rol muy importante al brindar la educación necesaria para generar personas independientes que vivan plenamente en la sociedad sin importar su condición

Disability is a condition (impairment) that hinders the development of daily activities and the interaction of the individual with the surrounding environment, it is divided into: physical, motor, organic, mental, intellectual and sensory disability. Objective: To document the perceptions and emotions on sexual and reproductive health of people with disabilities in the Biblián Canton Day Center. Methodology: This is a qualitative observational study in which the experiences of 34 people from the population with disabilities who are part of the Project Day Center "San José" of Biblián are collected, with five participants being selected through simple non-probabilistic sampling. Findings: From the analysis of the narratives, it is determined that people with disabilities maintain satisfactory relationships even with the insecurities that surround them. However, exclusion within their own homes, scarce safe information and mass media dissemination about sexuality have conditioned perceptions that expose them to a high level of vulnerability. By way of conclusion: On several occasions there are prejudices and taboos when talking about sexuality with people with disabilities in different homes, family members choose not to answer related questions, so health personnel play a very important role in providing the necessary education to generate independent people who live fully in society regardless of their condition

A deficiência é uma condição (impedimento) que dificulta o desenvolvimento das atividades cotidianas e a interação do indivíduo com o ambiente que o cerca. Ela se divide em: deficiência física, motora, orgânica, mental, intelectual e sensorial. Objetivo: documentar as percepções e emoções sobre saúde sexual e reprodutiva de pessoas com deficiência no Centro de Dia do Cantão de Biblián. Metodologia: trata-se de um estudo observacional qualitativo no qual são compiladas as experiências de 34 pessoas da população com deficiência que fazem parte do Projeto Centro de Dia "San José" em Biblián, sendo que cinco participantes foram selecionados por meio de amostragem simples não probabilística. Achados: A partir da análise das histórias, constatou-se que as pessoas com deficiência mantêm relacionamentos satisfatórios mesmo com as inseguranças que as cercam. Entretanto, a exclusão dentro de suas próprias casas, a escassez de informações seguras e a cobertura da sexualidade pela mídia de massa condicionaram percepções que as expõem a um alto nível de vulnerabilidade. Conclusão: Em várias ocasiões, há preconceitos e tabus ao falar sobre sexualidade com pessoas com deficiência em diferentes lares, e os membros da família optam por não responder às perguntas relacionadas, razão pela qual a equipe de saúde desempenha um papel muito importante ao fornecer a educação necessária para gerar pessoas independentes que vivem plenamente na sociedade, independentemente de sua condição

Experiencias y conocimientos, sobre salud sexual y reproductiva en personas con discapacidad en Ecuador

La discapacidad es una afección (deficiencia) que dificulta el desarrollo de las actividades cotidianas y la interacción del individuo con el entorno que lo rodea, se divide en: discapacidad física, motora, orgánica, mental, intelectual y sensorial. Objetivo: Documentar las percepciones y emociones en salud sexual y reproductiva de las personas con discapacidad del Centro diurno del Cantón Biblián. Metodología: Se trata de un estudio observacional cualitativo en el que se recopila las vivencias de 34 personas de la población con discapacidad que forman parte del Proyecto Centro diurno "San José" de Biblián, siendo seleccionados cinco participantes mediante muestreo simple no probabilístico. Hallazgos: A partir del análisis de los relatos se determina que las personas con discapacidad mantienen relaciones satisfactorias aún con las inseguridades que los rodean. Sin embargo, la exclusión dentro de sus propios hogares, la escasa información segura y la difusión mediática masiva sobre la sexualidad han condicionado percepciones que los expone a un nivel elevado de vulnerabilidad. A manera de Conclusión: En varias ocasiones existen prejuicios y tabúes al hablar de sexualidad con personas con discapacidad en los diferentes hogares, los familiares optan por no responder interrogantes relacionadas, por eso el personal de salud cumple un rol muy importante al brindar la educación necesaria para generar personas independientes que vivan plenamente en la sociedad sin importar su condición.

Disability is a condition (impairment) that hinders the development of daily activities and the interaction of the individual with the surrounding environment, it is divided into: physical, motor, organic, mental, intellectual and sensory disability. Objective: To document the perceptions and emotions on sexual and reproductive health of people with disabilities in the Biblián Canton Day Center. Methodology: This is a qualitative observational study in which the experiences of 34 people from the population with disabilities who are part of the Project Day Center "San José" of Biblián are collected, with five participants being selected through simple non-probabilistic sampling. Findings: From the analysis of the narratives, it is determined that people with disabilities maintain satisfactory relationships even with the insecurities that surround them. However, exclusion within their own homes, scarce safe information and mass media dissemination about sexuality have conditioned perceptions that expose them to a high level of vulnerability. By way of conclusion: On several occasions there are prejudices and taboos when talking about sexuality with people with disabilities in different homes, family members choose not to answer related questions, so health personnel play a very important role in providing the necessary education to generate independent people who live fully in society regardless of their condition.

A deficiência é uma condição (impedimento) que dificulta o desenvolvimento das atividades cotidianas e a interação do indivíduo com o ambiente que o cerca. Ela se divide em: deficiência física, motora, orgânica, mental, intelectual e sensorial. Objetivo: documentar as percepções e emoções sobre saúde sexual e reprodutiva de pessoas com deficiência no Centro de Dia do Cantão de Biblián. Metodologia: trata-se de um estudo observacional qualitativo no qual são compiladas as experiências de 34 pessoas da população com deficiência que fazem parte do Projeto Centro de Dia "San José" em Biblián, sendo que cinco participantes foram selecionados por meio de amostragem simples não probabilística. Achados: A partir da análise das histórias, constatou-se que as pessoas com deficiência mantêm relacionamentos satisfatórios mesmo com as inseguranças que as cercam. Entretanto, a exclusão dentro de suas próprias casas, a escassez de informações seguras e a cobertura da sexualidade pela mídia de massa condicionaram percepções que as expõem a um alto nível de vulnerabilidade. Conclusão: Em várias ocasiões, há preconceitos e tabus ao falar sobre sexualidade com pessoas com deficiência em diferentes lares, e os membros da família optam por não responder às perguntas relacionadas, razão pela qual a equipe de saúde desempenha um papel muito importante ao fornecer a educação necessária para gerar pessoas independentes que vivem plenamente na sociedade, independentemente de sua condição.

Brazilian Portuguese Translation and Validation of the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-IUGA revised.

INTRODUCTION AND HYPOTHESIS: Condition-specific sexual questionnaires are important patient-reported outcome measures. The aim of this study was to translate and validate the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association Revised (PISQ-IR) into Brazilian Portuguese and to clinically validate it in a Brazilian Portuguese-speaking population. METHODS: Translation and validation of the PISQ-IR was performed according to the International Urogynecological Association-recommended process and guidelines. For external validity, PISQ-IR subscales were compared with the clinical measures, Pelvic Organ Prolapse Quantification system (POP-Q) stage, pelvic floor muscle tone, and Oxford Grading Scale (Pearson correlations). Descriptive statistics, internal consistency (Cronbach's alpha coefficient), and test-retest reliability (interclass correlation coefficient) were calculated for all PISQ-IR subscales. RESULTS: A total of 120 sexually active and 106 not sexually active women were enrolled in the study between March 2015 and July 2019. Internal consistency was acceptable, with Cronbach's alpha values 0.60-0.80, except for the sexual arousal and orgasm, sexual arousal and partner-related issues, sexual arousal and condition-specific issues, global rating of sexual quality and condition impact subscales. PISQ-IR demonstrated good reliability (α > 0.6, CIC = 0.996). The agreement for each individual questionnaire item also individually presented substantial agreement between the assessments (κ 0.61-0.8). There was a correlation between PISQ-IR and POP, mixed, stress and fecal incontinence diagnosis and a positive correlation with pelvic floor muscle function according to the Oxford Scale in sexually active women. For sexually inactive women there was a correlation between PISQ-IR and mixed urinary symptoms. CONCLUSIONS: The Brazilian Portuguese version of PISQ-IR is a reliable and valid tool that can be easily used for the identification and assessment of sexual function in Brazilian Portuguese-speaking women with pelvic floor disorders.

COVID-19 pandemic exacerbation of disparities in access to public abortion services in Mexico.

BACKGROUND: We describe clients in Mexico City's public abortion programme, Interrupción Legal de Embarazo (ILE), during the COVID-19 pandemic and test whether the pandemic exacerbated inequities in access. METHODS: We conducted a cohort study of all abortions in the ILE programme from 1 January 2019 to 30 June 2022. We compared patients from within and outside the Mexico City Metropolitan area (ZMVM) by pandemic stage (pre-, acute-, mid- and late-COVID periods) and assessed changes in client characteristics (adolescent age, education, weeks' gestation) by place of residence (ZMVM vs outside the ZMVM) using linear probability models clustered on state. RESULTS: We included 45 031 abortions. The proportion of abortions to women who travelled from outside the ZMVM decreased from 6.5% pre-COVID to 4.4%-4.8% in in the acute, mid- and late-COVID periods. The adjusted probability of being an adolescent who travelled from outside the ZMVM dropped between pre-COVID (14.4%, 95% CI 12.7% to 16.1%) and mid-COVID (9.3%, 95% CI 7.9% to 10.7%). The proportion of abortions to women with a high school education stayed fairly flat among those travelling, while it rose among those residing in the ZMVM. The adjusted probability of presenting at 11 gestational weeks or greater was higher among women residing in the ZMVM in the pre-pandemic period; this flipped during all pandemic stages, with a higher probability of presenting at 11 weeks or greater among those who travelled from outside the ZMVM. CONCLUSIONS: The COVID-19 pandemic exacerbated existing disparities in who can access ILE services. To reduce inequities in access to essential health services, public sector abortion services should be made available in all Mexican states.

Let's talk about sex: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology: clinical recommendations after pelvic radiotherapy.

PURPOSE: The present consensus statement was developed by the GINECOR working group on behalf of the Spanish Society of Radiation Oncology (SEOR). This document addresses sexual health management in patients with gynaecological cancer after pelvic radiotherapy. METHODS: A modified two-round online Delphi study was conducted, where GINECOR members were surveyed on the diagnosis, treatment, and follow-up of sexual health problems. An expert panel of radiation oncologists, nurses and a gynaecologist participated in the Delphi study to reach a consensus, applying GRADE criteria to establish the level of agreement. RESULTS: The consensus recommendations cover both diagnosis and treatment, with an emphasis on patient-reported outcome measures (PROMs). They highlight recommendations such as the systematic assessment of genitourinary, gastrointestinal, and sexual symptoms, and the use of several treatments after radiotherapy. Recommendations include pharmacological options like vaginal lubricants and hormone therapy, and mechanical interventions such as vaginal dilators and vibrators. These suggestions stem from both scientific evidence and clinical expertise. CONCLUSION: This consensus statement describes a comprehensive, multidisciplinary approach developed to address the sexual needs and enhance the quality of life of patients with gynaecological tumours after pelvic radiotherapy. It offers specific recommendations for managing sexual issues, emphasizing the importance of specialized care and regular assessment. The document underscores the significance of proactive, patient-centered sexual health management in gynaecological cancer patients.

The effects of various therapies on vulvovaginal atrophy and quality of life in gynecological cancer patients: a systematic review.

PURPOSE: Tumors affecting the female genital tract and their treatments have the potential to induce adverse modifications in vaginal health and impact personal aspects of patient's lives. Vulvovaginal atrophy is one of the morphological changes observed in individuals with a history of gynecological cancer, influenced both by the biological environment of tumors and the main therapeutic modalities employed. Therefore, the purpose of this study was to identify approaches to treat vulvovaginal atrophy while assessing the impact on the emotional and sexual health of women diagnosed with gynecological cancers. METHODS: To achieve this goal, a systematic review was conducted following the methodological guidelines outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The databases used for literature research were PubMed and Web of Science. RESULTS: Initially, 886 articles were obtained. After eliminating duplicates and applying inclusion/exclusion criteria, seven articles were selected for analysis. The period of highest publication activity spanned from 2017 to 2020, with the majority conducted in Italy. Five treatment modalities were identified and categorized as vaginal suppository, oral medication, surgical procedure, CO2 laser therapy, and vaginal dilator. Twenty-four outcomes related to vaginal health and 30 outcomes related to overall, sexual, and emotional quality of life were analyzed. CONCLUSION: In general, all interventions demonstrated the ability to improve vaginal health or, at the very least, the sexual health of patients. Thus, despite limitations, all treatments have the potential to address vulvovaginal atrophy in patients with a history of gynecological cancer.

Gender-transformative school-based sexual health intervention: study protocol for a randomized controlled trial.

BACKGROUND: There is general agreement that sexuality is a central aspect of human development; it is key in sexual health and reproductive education during adolescence. However, in spite of the existing interventions on this topic and the evidence generated, the inclusion of a gender focus in sexuality is relatively recent and there is little evidence available, thus structured and corroborated interventions with a gender-transforming perspective in sexuality are required. METHODS: We will use a mixed method experimental design with a parallel cluster-randomized trial (GRTs) that will evaluate the effectiveness of a comprehensive gender-transformative intervention of sexual education (ENFOCATE -Focus-on-), which will be complemented with qualitative studies to understand the implementation process. The participants will be 609 10th and 11th-grade students. The randomization will be by grade, and the data will be collected at three moments (pre-intervention, post-intervention, and a 3-month follow-up). DISCUSSION: Comprehensive, gender-focused, and culturally pertinent interventions in sexuality are needed for adolescents of countries with high, middle, and low incomes. These produce better results in terms of sexual health, and including a gender-transformative focus contributes to equity in health. Focus-on is unique since it uses a comprehensive gender-transformative intervention in sexual education that will allow putting into practice a program based both on international evidence and that which arises from the object population. It also uses a culturally-sensitive focus, since it is designed based on the characteristics of the object population; it will allow adapting some activities to the needs of the context in which it is developed. TRIAL REGISTRATION: The study was prospectively registered on June 6, 2023, at ClinicalTrials.gov ID: NCT05896540. Protocol version number 1.0. May 22, 2023.

Vivencias y estrategias comunitarias de manejo del riesgo dentro de las prácticas chemsex: un estudio cualitativo / Community experiences and strategies of risk management within chemsex practices: a qualitative study

Resumen El auge en el estudio del uso sexualizado de drogas entre hombres gais, bisexuales u otros hombres que tienen sexo con hombres (HSH), conocido como chemsex, ha generado una multiplicidad de datos que contribuyen a su problematización en tanto cuestión de salud pública a través del vínculo con el VIH y las adicciones. El estudio de estas prácticas, desde un paradigma biomédico, se ha centrado en el riesgo y ha contribuido a su reducción como fenómeno único y cuantificable. Este estudio tiene como objetivo explorar la vivencia del riesgo en el transcurso de las prácticas, para conocer qué estrategias de manejo emplean frente a éste y de qué manera son generadas. Se realizaron entrevistas semiestructuradas a cinco practicantes de chemsex en el Área Metropolitana de Barcelona y, posteriormente se aplicó un análisis temático. Los hallazgos muestran cómo estos hombres detectan, asumen y enfrentan los riesgos presentes en estas prácticas, donde toman relevancia el tipo de relaciones que allí se dan y el círculo social del que disponen. Este estudio destaca también la creación de estrategias basadas en la experiencia y cómo la transmisión de estos saberes entre participantes facilita la toma de decisiones y el manejo del riesgo.

Abstract The rise in the study of sexualised drug use among gay, bisexual and other men who have sex with men (MSM), known as chemsex, has generated a multiplicity of data that contribute to its problematisation as a public health issue through the link with HIV and addictions. The study of these practices, from a biomedical paradigm, has focused on risk and has contributed to its reduction as a unique and quantifiable phenomenon. This study aims to explore the experience of risk in the course of the practices, to find out what management strategies they employ in the face of risk and how they are generated. Semi-structured interviews were conducted with five chemsex practitioners in the Metropolitan Area of Barcelona and, subsequently, a thematic analysis was applied. The findings show how these men detect, assume and confront the risks present in these practices, where the type of relationships that take place and the social circle available to them are relevant. This study also highlights the creation of strategies based on experience and how the transmission of this knowledge among participants facilitates decision-making and risk management.

Ist/hiv/aids: estratégias de prevenção para mulheres que fazem sexo com mulheres / Ist/hiv/aids: prevention strategies for women who have sex with women / Ist/vih/sida: estrategias de prevención para mujeres que tienen relaciones sexuales con mujeres

Objetivo: Identificar as estratégias de prevenção às Infecções Sexualmente Transmissíveis/HIV/Aids conhecidas por mulheres que fazem sexo com mulheres. Métodos: Pesquisa de campo com abordagem qualitativa exploratória. Para a coleta de dados, optou-se pela técnica de amostragem não probabilística bola de neve, realizada por meio de entrevistas online, conduzidas no período de novembro de 2022 a abril de 2023. Todos os momentos foram registrados e, em seguida, transcritos integralmente para análise. A perspectiva da interseccionalidade e vulnerabilidade guiaram a análise, focalizando as estratégias de prevenção e a atuação dos profissionais de saúde no atendimento às MSM. Resultados: Participaram da pesquisa 22 mulheres, jovens, em sua maioria naturais da Bahia, brancas, sem religião, com ensino superior e renda familiar entre 2 e 4 salários-mínimos. Os achados demonstraram que as estratégias de prevenção das IST/ HIV/Aids são conhecidas pelas mulheres, no entanto são pouco usuais, considerando que o aprendizado sobre elas se deu a partir das escolas, família e amigos e eles discorrem sobre as práticas heterossexuais, não sendo pertinente as adaptações para o sexo entre mulheres com vulvas. Conclusão: As estratégias de prevenção às IST/HIV/Aids são então caracterizadas como adaptações, sobretudo pela escassez de estudos que asseguram a sua efetividade. (AU)

Objective: To identify prevention strategies for Sexually Transmitted Infections (STI)/HIV/AIDS known to women who have sexy with women (WSW). Methods: A qualitative exploratory field study was conducted. Data collection utilized a snowball non-probabilistic sampling technique, with online interviews conducted from November 2022 to April 2023. All interactions were recorded and subsequently transcribed verbatim for analysis. The perspectives of intersectionality and vulnerability guided the analysis, focusing on prevention strategies and the role of healthcare professionals in serving WSW. Results: The study included 22 participants, predominantly young women from Bahia, of white ethnicity, without religious affiliation, with a college education, and a family income ranging from 2 to 4 minimum wages. Findings indicated that while women were aware of prevention strategies for STI/HIV/AIDS, they were infrequently utilized. Knowledge about these strategies primarily came from schools, family, and friends, which predominantly discussed heterosexual practices, with little relevance to adaptations for vulva-to-vulva sexual activity. Conclusion: Prevention strategies for STI/HIV/AIDS among WSW are thus characterized as adaptations, particularly due to the scarcity of studies ensuring their effectiveness. (AU)

Objetivo: Identificar las estrategias de prevención de Infecciones de Transmisión Sexual (ITS)/VIH/SIDA conocidas por las mujeres que tienen relaciones sexuales con mujeres (MSM). Métodos: Se realizó una investigación de campo con enfoque cualitativo exploratorio. Para la recolección de datos, se optó por la técnica de muestreo no probabilístico de bola de nieve, llevada a cabo a través de entrevistas en línea, realizadas desde noviembre de 2022 hasta abril de 2023. Todos los momentos fueron registrados y posteriormente transcritos íntegramente para su análisis. Las perspectivas de interseccionalidad y vulnerabilidad guiaron el análisis, centrándose en las estrategias de prevención y la actuación de los profesionales de la salud en la atención a las MSM. Resultados: Participaron en la investigación 22 mujeres, en su mayoría jóvenes, nativas de Bahía, blancas, sin afiliación religiosa, con educación superior y un ingreso familiar entre 2 y 4 salarios mínimos. Los hallazgos demostraron que las estrategias de prevención de ITS/VIH/SIDA son conocidas por las mujeres, sin embargo, son poco comunes, considerando que el aprendizaje sobre ellas proviene de la escuela, la familia y los amigos, quienes hablan sobre prácticas heterosexuales, sin que sean pertinentes las adaptaciones para el sexo entre mujeres con vulvas. Conclusion: Las estrategias de prevención de ITS/VIH/SIDA se caracterizan así como adaptaciones, principalmente debido a la escasez de estudios que garanticen su efectividad. (AU)

Vulnerabilidades relacionadas a saúde sexual de mulheres atendidas em um consultório de enfermagem / Vulnerabilities related to the sexual health of women attended in a nursing office / Vulnerabilidades relacionadas con la salud sexual de mujeres atendidas en un consultorio de enfermería

Objetivo: Descrever o perfil de saúde sexual de mulheres atendidas no Consultório de Enfermagem de uma instituição de ensino superior. Métodos: Estudo descritivo com abordagem quantitativa utilizando a técnica documental retrospectiva realizado por meio da coleta de dados de prontuários das usuárias atendidas em um Consultório de Enfermagem. Resultados: Foram analisados 303 (100%) prontuários. Houve predominância de mulheres, solteiras (50,17%); pardas/pretas 80 (26,41%); heterossexuais (86,80%); cisgêneras (97,36%); cristãs (72,94%), com uma parceria sexual (65,35%) e na faixa etária entre 40 a 59 anos (42,24%). Conclusão: Identificamos que alguns determinantes sociais, sobretudo a idade, estado civil e cor, podem estar vinculados a ocorrência de infecção sexualmente transmissível, dispareunia/sinusorragia e violência psicológica. Sugere-se que políticas públicas sejam de fato instituídas, com vistas à promoção e proteção da saúde das mulheres. (AU)

Objective: To describe the sexual health profile of women attended at the Nursing Office of a higher education institution. Methods: Descriptive study with a quantitative approach using the retrospective documentary technique performed by collecting data from medical records of users attended at a Nursing Office. Results: 303 (100%) medical records were analyzed. There was a predominance of single women (50,17%); brown/black 80 (26,41%); heterosexuals (86,80%); cisgenus (97,36%); Christians (72,94%), with a sexual partner (65,35%) and aged between 40 and 59 years (42,24%). Conclusion: We identified that some social determinants, especially age, marital status and color, linked to the occurrence of sexually transmitted infection, dyspareunia/sinusorrhagia and psychological violence. It is suggested that public policies are actually instituted, with a view to promoting and protecting women's health. (AU)

Objetivo: Describir el perfil de salud sexual de las mujeres atendidas en la Oficina de Enfermería de una institución de educación superior. Métodos: Estudio descriptivo con abordaje cuantitativo utilizando la técnica documental retrospectiva realizada mediante la recolección de datos de las historias clínicas de los usuarios atendidos en un Consultorio de Enfermería. Resultados: Se analizaron 303 (100%) historias clínicas. Predominio hubo de mujeres solteras (50,17%); marrón / negro 80 (26,41%); heterosexuales (86,80%); cisgénico (97,36%); Cristianos (72,94%), como pareja sexual (65,35%) en un grupo de 40 a 59 años (42,24%). Conclusión: Identificamos que algunos determinantes sociales, principalmente la edad, el estado civil y el color, están vinculados a la ocurrencia de Infección transmitida sexualmente, dispareunia / sinitismo y violencia psicológica. Sugerir que se instituyan políticas públicas, con miras a promover y proteger la salud de la mujer. (AU)

Sociodemographic and obstetric factors may affect breastfeeding attitudes, self-efficacy, and knowledge in women with rheumatic diseases: a retrospective analysis of self-reported surveys.

Women with autoimmune rheumatic disease (ARDs) experience difficulties with BF in addition to those concerning their own disease. The aim of this study is to identify the impact factors as infant feeding attitude, the level of BF knowledge, BF self-efficacy, and the sociodemographic have in the intention to BF in women with ARDs. We performed an observational, retrospective, and analytical study. Reproductive-age women (18-50 years old) with ARDs with prior pregnancy history and who filled out self-reported BF surveys as part of the Rheumatology Integral Care Program were included. Sociodemographic and clinical characteristics were retrieved from medical charts. We analyzed three validated BF questionnaires. Sixty-five participants with a mean age of 41.32 ± 7.48 were evaluated. Of these, 63 (97%) women agreed with BF in the first 6 months. The most prevalent infant feeding attitude was neutral with 42 (64.6%) women. The most common level of BF knowledge was poor with 45 (69.2%) patients. There were significant correlations of BF knowledge with education years (p = < 0.001, r = 0.464) and age (p = 0.049, r=-0.245). A significant correlation was found between BF self-efficacy and age (p = 0.039, r = 0.257). Attitude toward BF was significantly associated with education level > 9 years (OR = 3.400; 95% CI = 1.091-10.593) and a history of miscarriage (OR = 3.670; 95% CI = 1.051-12.813). Although most women with ARDs agreed with BF, we identified a poor level of BF knowledge and a neutral infant feeding attitude as the most predominant. By identifying this data in women with ARDs, BF practices may be improved.

Cross-Cultural Adaptation and Face Validation of the Chilean Version of the Operated Male to Female Sexual Function Index.

INTRODUCTION AND HYPOTHESIS: Transgender and gender-diverse people often experience discrimination or even outright exclusion when undergoing medical attention. It has been shown that gender-affirming treatments improve quality of life in transgender patients, and genital-affirming surgery (GAS) is increasingly spreading worldwide. Sexual function after male-to-female GAS has long been evaluated by using tools designed for assigned female at birth (AFAB), resulting in suboptimal assessments. Currently, the operated Male to Female Sexual Function Index (oMtFSFI) is the only validated questionnaire to assess the sexual function of operated transgender women. The current study was aimed at performing cross-cultural adaptation and to test the face validity of the Chilean version of the oMtFSFI. METHODS: We carried out an observational descriptive study. The questionnaire was translated into Spanish, adapted, and face validated in five phases with eight participants. The study was approved by the Universidad del Desarrollo Scientific Ethics Committee. RESULTS: According to participants, the questionnaire was shown to both pertinently and exhaustively evaluate the sexual function of post-feminizing genitoplasty transgender women. The questionnaire was well understood by the participants, except for a difficulty in understanding certain terms. Some participants criticized the perspective of the instrument in terms of the assumption of having a partner or having penetrative intercourse via the neovagina. The amendments to the Italian version of the questionnaire were discussed until an agreement on adaptation considering the patient´s perspective was reached. The present preliminary data support the face validity of the Chilean version of the oMtFSFI in the assessment of sexual function in operated transgender women. CONCLUSIONS: This adapted questionnaire could be a valuable tool for clinicians and researchers.

Internet-Based Access to Sexual and Reproductive Health Services Among Colombian Youth: A Cross-Sectional Study.

Introduction: Sexual and reproductive health (SRH) is a sensitive subject, and young people may be unfamiliar with how to access SRH services. In this cross-sectional study, we examined young people's internet use to understand how they accessed SRH clinics in Colombia. This study also explored Colombian youth's interest in online material teaching how to access SRH services. Methods: During August 2019-February 2020, patients aged 10-24 years old presenting at two SRH clinics in Colombia were invited to answer a survey. Chi-square tests were performed to assess possible differences in how participants inquired how to access the clinic according to sociodemographic characteristics. Results: Among the 812 patients who participated, 91.4% were female and the median age was 19 years. To inquire how to access the SRH clinic, 30.7% of participants asked their parent(s) and 24.0% used the internet. Participants aged 20-24 years old were more likely to use the internet compared to younger participants (p < .001). Most respondents (81.5%) were interested in the availability of online material explaining how to access SRH services. Conclusions: While Colombian youth learned about how to access SRH clinics from several different sources, the vast majority indicated their interest in having access to online materials explaining how to access SRH services.

Human papillomavirus infection: Epidemiology, biology, host interactions, cancer development, prevention, and therapeutics.

Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections worldwide. It is caused by the HPV, a DNA virus that infects epithelial cells in various mucous membranes and skin surfaces. HPV can be categorised into high-risk and low-risk types based on their association with the development of certain cancers. High-risk HPV types, such as HPV-16 and HPV-18, are known to be oncogenic and are strongly associated with the development of cervical, anal, vaginal, vulvar, penile, and oropharyngeal cancers. These types of HPV can persist in the body for an extended period and, in some cases, lead to the formation of precancerous lesions that may progress to cancer if left untreated. Low-risk HPV types, such as HPV-6 and HPV-11, are not typically associated with cancer but can cause benign conditions like genital warts. Genital warts are characterised by the growth of small, cauliflower-like bumps on the genital and anal areas. Although not life-threatening, they can cause discomfort and psychological distress. HPV is primarily transmitted through sexual contact, including vaginal, anal, and oral sex. It can also be transmitted through non-penetrative sexual activities that involve skin-to-skin contact. In addition to sexual transmission, vertical transmission from mother to child during childbirth is possible but relatively rare. Prevention of HPV infection includes vaccination and safe sexual practices. HPV vaccines, such as Gardasil and Cervarix, are highly effective in preventing infection with the most common high-risk HPV types. These vaccines are typically administered to adolescents and young adults before they become sexually active. Safe sexual practices, such as consistent and correct condom use and limiting the number of sexual partners, can also reduce the risk of HPV transmission. Diagnosis of HPV infection can be challenging because the infection is often asymptomatic, especially in men. In women, HPV testing can be done through cervical screening programs, which involve the collection of cervical cells for analysis. Abnormal results may lead to further diagnostic procedures, such as colposcopy or biopsy, to detect precancerous or cancerous changes. Overall, HPV infection is a prevalent sexually transmitted infection with significant implications for public health. Vaccination, regular screening, and early treatment of precancerous lesions are key strategies to reduce the burden of HPV-related diseases and their associated complications. Education and awareness about HPV and its prevention are crucial in promoting optimal sexual health. This study aimed to carry out a literature review considering several aspects involving HPV infection: Global distribution, prevalence, biology, host interactions, cancer development, prevention, therapeutics, coinfection with other viruses, coinfection with bacteria, association with head and neck squamous cell carcinomas, and association with anal cancer.

A Mixed-Methods Study Exploring Colombian Adolescents' Access to Sexual and Reproductive Health Services: The Need for a Relational Autonomy Approach.

This study's objective was to understand Colombian adolescents' experiences and preferences regarding access to sexual and reproductive health services (SRHS), either alone or accompanied. A mixed-method approach was used, involving a survey of 812 participants aged eleven to twenty-four years old and forty-five semi-structured interviews with participants aged fourteen to twenty-three. Previous research shows that adolescents prefer privacy when accessing SRHS and often do not want their parents involved. Such findings align with the longstanding tendency to frame the ethical principle of autonomy as based on independence in decision-making. However, the present study shows that such a conceptualization and application of autonomy does not adequately explain Colombian adolescent participants' preferences regarding access to SRHS. Participants shared a variety of preferences to access SRHS, with the majority of participants attaching great importance to having their parents involved, to varying degrees. What emerges is a more complex and non-homogenous conceptualization of autonomy that is not inherently grounded in independence from parental involvement in access to care. We thus argue that when developing policies involving adolescents, policymakers and health professionals should adopt a nuanced "relational autonomy" approach to better respect the myriad of preferences that Colombian (and other) adolescents may have regarding their access to SRHS.