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1.
Risk Anal ; 2024 Aug 02.
Artigo em Inglês | MEDLINE | ID: mdl-39091168

RESUMO

Earthquake insurance is a critical risk management strategy that contributes to improving recovery and thus greater resilience of individuals. Insurance companies construct premiums without taking into account spatial correlations between insured assets. This leads to potentially underestimating the risk, and therefore the exceedance probability curve. We here propose a mixed-effects model to estimate losses per ward that is able to account for heteroskedasticity and spatial correlation between insured losses. Given the significant impact of earthquakes in New Zealand due to its particular geographical and demographic characteristics, the government has established a public insurance company that collects information about the insured buildings and any claims lodged. We thus develop a two-level variance component model that is based on earthquake losses observed in New Zealand between 2000 and 2021. The proposed model aims at capturing the variability at both the ward and territorial authority levels and includes independent variables, such as seismic hazard indicators, the number of usual residents, and the average dwelling value in the ward. Our model is able to detect spatial correlation in the losses at the ward level thus increasing its predictive power and making it possible to assess the effect of spatially correlated claims that may be considerable on the tail of loss distribution.

2.
Huan Jing Ke Xue ; 45(8): 4980-4992, 2024 Aug 08.
Artigo em Chinês | MEDLINE | ID: mdl-39168713

RESUMO

Based on the entropy weight TOPSIS method to measure the development level of "zero-waste cities" in China from 2004 to 2021, the social network analysis method and spatial Durbin model were used to explore the spatial correlation network structure and impact mechanism of the development level of "zero-waste cities." The results showed that: ① The development level of "zero-waste cities" was generally on the decline in the whole country and the eastern and central regions. However, it was on the rise in the western regions. ② The spatial correlation of the development level of "zero-waste cities" presented a core-edge structure, with an overall upward trend in network density and a stable state in the overall network. ③ Beijing, Shanghai, Jiangsu, Zhejiang, Fujian, and Guangdong were at the center and dominant position of the network. ④ Beijing, Tianjin, Shanghai, and Jiangsu belonged to the "net benefit" sector; Zhejiang, Fujian, and Guangdong belonged to the "broker" sector; and the other provinces belonged to the "net overflow" sectors. ⑤ The level of urbanization, economic development, technological innovation, foreign investment, environmental regulations, government intervention, and population size had a significant impact on the development level of "zero-waste cities" in local or neighboring provinces, respectively. The research results can provide a reference for the proposal of policies for constructing and coordinating the development of "zero-waste cities" in various regions.

3.
Sci Rep ; 14(1): 17402, 2024 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-39075083

RESUMO

In the information age, digital information technology has gradually become a new quality of productivity to improve international competitiveness, and the status and importance of the pseudo human settlements(PHS) constructed by digital and information has been increasing in the human settlements(HS) system. In this context, exploring the coupling coordination of the internal systems of the PHS provides a theoretical basis for promoting the comprehensive improvement of the quality of the HS in the urban agglomerations, provides a theoretical reference for rationally interpreting the new type of human-land relationship in the information age, and provide a new perspective for the study of the human settlements geography. Currently, research on PHS is in its nascent stages, therefore, we construct a theoretical framework for the coupling coordination of the "three states" of the HS, takes the internal system of PHS as the entry point, empirically analyze the spatiotemporal characteristics of the PHS coupling coordination degree within urban agglomerations in eastern China and the driving factors by using the coupling coordination degree, spatial autocorrelation, the center of gravity and the ellipse of the standard deviation, and geo-detector models. Research shows: (1) Time course: exhibits an upward "inverted L" trend. (2) Spatial pattern: exhibits a general spatial pattern of "high in the north and low in the south". (3) Spatial correlation: shows a spatially positively correlated clustering trend. (4) Spatial evolution: demonstrates a decentralized pattern of migration from the northeast to the southwest, indicating that the coupling coordination grows faster in the southwest than in the northeast. (5) Driving factor: the development of coupling coordination degree of PHS results from multiple factors and systems. This research provides theoretical support for promoting the comprehensive improvement of the quality of PHS in the urban agglomerations in eastern China, and offers scientific reference for the construction of PHS in other regions of China.

4.
Sci Total Environ ; 948: 174282, 2024 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-38960164

RESUMO

Poisoning caused by coumarin-type anticoagulant rodenticides (ARs) stands as the predominant method for controlling rodents globally. ARs, through secondary poisoning, pose a significant threat to predators due to their lethal and sublethal effects. We examined the concentration of accumulated ARs in liver samples of mostly road-killed steppe polecats (Mustela eversmanii) and European polecats (M. putorius) collected throughout Hungary between 2005 and 2021. The steppe polecat samples were found mainly from Eastern Hungary, while European polecats from Western Hungary. We measured the concentration of six residues by HPLC-FLD. Our analysis revealed the presence of one first-generation and four second-generation ARs in 53% of the steppe polecat (36) and 39% of the European polecat (26) samples. In 17 samples we detected the presence of at least two AR compounds. Although we did not find significant variance in AR accumulation between the two species, steppe polecats displayed greater prevalence and maximum concentration of ARs, whereas European polecat samples exhibited a more diverse accumulation of these compounds. Brodifacoum and bromadiolone were the most prevalent ARs; the highest concentrations were 0.57 mg/kg and 0.33 mg/kg, respectively. The accumulation of ARs was positively correlated with human population density and negatively correlated with the extent of the more natural habitats in both species. To the best of our knowledge, this is the first study to demonstrate anticoagulant rodenticide exposure in steppe polecats globally, and for European polecats in Central European region. Although the extent of AR accumulation in European polecat in Hungary appears comparatively lower than in many other European countries, the issue of secondary poisoning remains a serious problem as these ARs intrude into food webs. Reduced and more prudent usage of pesticides would provide several benefits for wildlife, included humans. However, we advocate a prioritization of ecosystem services through the complete prohibition of the toxicants.


Assuntos
Anticoagulantes , Monitoramento Ambiental , Rodenticidas , Animais , Anticoagulantes/análise , Hungria , Mustelidae , Poluentes Ambientais/análise
5.
Ann Appl Stat ; 18(1): 468-486, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38846637

RESUMO

Image-on-scalar regression has been a popular approach to modeling the association between brain activities and scalar characteristics in neuroimaging research. The associations could be heterogeneous across individuals in the population, as indicated by recent large-scale neuroimaging studies, for example, the Adolescent Brain Cognitive Development (ABCD) Study. The ABCD data can inform our understanding of heterogeneous associations and how to leverage the heterogeneity and tailor interventions to increase the number of youths who benefit. It is of great interest to identify subgroups of individuals from the population such that: (1) within each subgroup the brain activities have homogeneous associations with the clinical measures; (2) across subgroups the associations are heterogeneous, and (3) the group allocation depends on individual characteristics. Existing image-on-scalar regression methods and clustering methods cannot directly achieve this goal. We propose a latent subgroup image-on-scalar regression model (LASIR) to analyze large-scale, multisite neuroimaging data with diverse sociode-mographics. LASIR introduces the latent subgroup for each individual and group-specific, spatially varying effects, with an efficient stochastic expectation maximization algorithm for inferences. We demonstrate that LASIR outperforms existing alternatives for subgroup identification of brain activation patterns with functional magnetic resonance imaging data via comprehensive simulations and applications to the ABCD study. We have released our reproducible codes for public use with the software package available on Github.

6.
Sci Rep ; 14(1): 14368, 2024 Jun 22.
Artigo em Inglês | MEDLINE | ID: mdl-38909046

RESUMO

As urban development accelerates and natural disasters occur more frequently, the urgency of developing effective emergency shelter planning strategies intensifies. The shelter location selection method under the traditional multi-criteria decision-making framework suffers from issues such as strong subjectivity and insufficient data support. Artificial intelligence offers a robust data-driven approach for site selection; however, many methods neglect the spatial relationships of site selection targets within geographical space. This paper introduces an emergency shelter site selection model that combines a variational graph autoencoder (VGAE) with a random forest (RF), namely VGAE-RF. In the constructed urban spatial topological graph, based on network geographic information, this model captures both the latent features of geographic unit coupling and integrates explicit and latent features to forecast the likelihood of emergency shelters in the construction area. This study takes Beijing, China, as the experimental area and evaluates the reliability of different model methods using a confusion matrix, Receiver Operating Characteristic (ROC) curve, and Imbalance Index of spatial distribution as evaluation indicators. The experimental results indicate that the proposed VGAE-RF model method, which considers spatial semantic associations, displays the best reliability.

7.
Neurobiol Dis ; 198: 106549, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38830476

RESUMO

BACKGROUND: Multiple system atrophy (MSA) and Parkinson's disease (PD) are neurodegenerative disorders characterized by α-synuclein pathology, disrupted iron homeostasis and impaired neurochemical transmission. Considering the critical role of iron in neurotransmitter synthesis and transport, our study aims to identify distinct patterns of whole-brain iron accumulation in MSA and PD, and to elucidate the corresponding neurochemical substrates. METHODS: A total of 122 PD patients, 58 MSA patients and 78 age-, sex-matched health controls underwent multi-echo gradient echo sequences and neurological evaluations. We conducted voxel-wise and regional analyses using quantitative susceptibility mapping to explore MSA or PD-specific alterations in cortical and subcortical iron concentrations. Spatial correlation approaches were employed to examine the topographical alignment of cortical iron accumulation patterns with normative atlases of neurotransmitter receptor and transporter densities. Furthermore, we assessed the associations between the colocalization strength of neurochemical systems and disease severity. RESULTS: MSA patients exhibited increased susceptibility in the striatal, midbrain, cerebellar nuclei, as well as the frontal, temporal, occipital lobes, and anterior cingulate gyrus. In contrast, PD patients displayed elevated iron levels in the left inferior occipital gyrus, precentral gyrus, and substantia nigra. The excessive iron accumulation in MSA or PD correlated with the spatial distribution of cholinergic, noradrenaline, glutamate, serotonin, cannabinoids, and opioid neurotransmitters, and the degree of this alignment was related to motor deficits. CONCLUSIONS: Our findings provide evidence of the interaction between iron accumulation and non-dopamine neurotransmitters in the pathogenesis of MSA and PD, which inspires research on potential targets for pharmacotherapy.


Assuntos
Atrofia de Múltiplos Sistemas , Doença de Parkinson , Humanos , Atrofia de Múltiplos Sistemas/metabolismo , Atrofia de Múltiplos Sistemas/diagnóstico por imagem , Atrofia de Múltiplos Sistemas/patologia , Doença de Parkinson/metabolismo , Doença de Parkinson/diagnóstico por imagem , Doença de Parkinson/patologia , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Encéfalo/metabolismo , Encéfalo/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Ferro/metabolismo , Neurotransmissores/metabolismo , Mapeamento Encefálico/métodos
8.
J Environ Manage ; 359: 121005, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38710147

RESUMO

With digital technological change and the increasing frequency of interregional innovation links, the spatial correlation and diversity of strategic emerging industries' green innovation efficiency (SEI-GIE) need to be explored in depth. This paper innovatively constructs the SEI-GIE input-output index system under digital economy. The proposed grey model FINGBM(1,1) with ω-order accumulation and weighted initial value optimization realizes effective prediction of 7 input-output indicators of 30 provinces in China from 2021 to 2025. Super-SBM-DEA, gravity model, and social network analysis are applied to explore spatial network structure's dynamic process of SEI-GIE from 12th to 14th Five-Year-Plan period (2011-2025). Empirical results show that (1) Under the effect of digital economy, the SEI-GIE in China generally shows a U-shaped fluctuation trend, in which the growth trend in the central region is obvious, and the western region shows significant fluctuations. (2) The spatial correlation network of SEI-GIE presents a complex and stable center-periphery circle. Particularly, the overall increase in network efficiency highlights the strong small-world characteristics. (3) Beijing, Shanghai, Zhejiang and Jiangsu have always been in the leading core position, with strong influence and control; And Tianjin's core position in the network will decline. Additionally, Guangxi and Chongqing have great potential, but Guangdong needs to strengthen its radiation effect. (4) Block model shows that plate-I (Beijing, Tianjin) receive spatial spillovers from others, while plates-III,IV have significant spillover effects. This study provides theoretical reference for policymakers from a network perspective to promote development of China's SEI-GIE.


Assuntos
Análise de Rede Social , China , Indústrias , Modelos Teóricos , Invenções
9.
Comput Biol Med ; 172: 108261, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38508056

RESUMO

Whole heart segmentation (WHS) has significant clinical value for cardiac anatomy, modeling, and analysis of cardiac function. This study aims to address the WHS accuracy on cardiac CT images, as well as the fast inference speed and low graphics processing unit (GPU) memory consumption required by practical clinical applications. Thus, we propose a multi-residual two-dimensional (2D) network integrating spatial correlation for WHS. The network performs slice-by-slice segmentation on three-dimensional cardiac CT images in a 2D encoder-decoder manner. In the network, a convolutional long short-term memory skip connection module is designed to perform spatial correlation feature extraction on the feature maps at different resolutions extracted by the sub-modules of the pre-trained ResNet-based encoder. Moreover, a decoder based on the multi-residual module is designed to analyze the extracted features from the perspectives of multi-scale and channel attention, thereby accurately delineating the various substructures of the heart. The proposed method is verified on a dataset of the multi-modality WHS challenge, an in-house WHS dataset, and a dataset of the abdominal organ segmentation challenge. The dice, Jaccard, average symmetric surface distance, Hausdorff distance, inference time, and maximum GPU memory of the WHS are 0.914, 0.843, 1.066 mm, 15.778 mm, 9.535 s, and 1905 MB, respectively. The proposed network has high accuracy, fast inference speed, minimal GPU memory consumption, strong robustness, and good generalization. It can be deployed to clinical practical applications for WHS and can be effectively extended and applied to other multi-organ segmentation fields. The source code is publicly available at https://github.com/nancy1984yan/MultiResNet-SC.


Assuntos
Coração , Software , Coração/diagnóstico por imagem , Tomografia Computadorizada por Raios X
10.
Huan Jing Ke Xue ; 45(3): 1243-1253, 2024 Mar 08.
Artigo em Chinês | MEDLINE | ID: mdl-38471841

RESUMO

Based on the whole life cycle perspective, the carbon emissions of the provincial construction industry in China from 2011 to 2019 were calculated from the production, construction, operation, and demolition stages of building materials. A spatial correlation network matrix of the carbon emissions in the construction industry was constructed by using the modified gravity model, and the structural characteristics of the correlation network were described by introducing social network analysis. Through the quadratic assignment program, the spatial correlation matrix of carbon emissions in the construction industry and its influencing factors were regressed and analyzed. The conclusions were as follows:① the spatial correlation network of carbon emissions in China's construction industry clearly existed. The network density and network correlation numbers were gradually rising, and the network tightness and stability were gradually improving. ② Shanghai, Tianjin, Beijing, and Jiangsu had a higher degree centrality and closeness centrality, which are the core and dominant positions of the spatial correlation network of carbon emissions in the construction industry. Zhejiang replaced Shanghai in the top four from 2013 to 2018, and the betweenness centrality of each province had unbalanced characteristics. ③ Beijing, Tianjin, Jiangsu, Inner Mongolia, Shanghai, and Shandong were "net beneficiaries" blocks, receiving the carbon emissions from other regions. Four provinces, Guangdong, Chongqing, Fujian, and Shandong, belonged to the "broker" sector, achieving a dynamic balance between the production and consumption sides of building carbon emissions. The remaining 20 provinces played a "net spillovers" role, actively sending carbon emissions from the construction industry to other provinces. The correlation between blocks was much greater than the correlation relationship within the blocks. ④ Industrial structure, urban population, spatial adjacency, consumption level, and construction industry process structure had a significant influence on the spatial correlation of carbon emissions in the construction industry. The greater the inter-provincial differences in industrial structure, urban population, spatial adjacency, and consumption level, the greater the similarity of inter-provincial construction industry process structure, and the stronger the spatial correlation and spatial spillover of the construction industry carbon emissions. Finally, according to the evolution characteristics and influencing factors of the spatial correlation network of building carbon emissions, relevant countermeasures and suggestions were provided for the collaborative carbon reduction development of the construction industry region.

11.
Environ Sci Pollut Res Int ; 31(16): 23728-23746, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38424245

RESUMO

In the context of regional integration, it is more than crucial to compare and analyze the spatial correlation network structure and formation mechanism of high-quality economic development in the Yangtze River Economic Belt and the Yellow River Basin urban cities as an attempt to strengthen collaborative work on high-quality economic development in both river basins. The paper measured high-quality economic development of the Yangtze River Economic Belt and the Yellow River Basin from 2010 to 2021. Then, it employed social network analysis and the QAP method to study the network structure's characteristics and formation mechanism. The conclusion of the research illustrates a few points clearly that first, the high-quality economic development of the two rivers presents a complex and multithreaded network structure. Although the network structure is hold at a comparatively stable state, the correlation degree needs improvement. Second, cities such as Chongqing, Wuhan, Hefei, Nanjing, Hangzhou, Shanghai, and Changsha and cities like Zhengzhou, Xi'an, Luoyang, Yulin, Hulunbuir, Ordos, and Nanyang are at the very central as well as central position of the network. The spatial correlation networks of the Yangtze River Economic Belt and the Yellow River Basin can be divided into four plates: "agent plate," "main outflow plate," "bidirectional spillover plate," and "main inflow plate." Third, reverse geographical distance and differences in the digital economy attach great significance to the spatial correlation networks of the two basins. The difference in urbanization level makes significant impacts only on the spatial correlation network of the Yangtze River Economic Belt, while the difference in environmental regulation and material capital accumulation only significantly influences the spatial correlation network of the Yellow River Basin.


Assuntos
Desenvolvimento Econômico , Rios , China , Cidades , Geografia
12.
Cell Rep ; 43(2): 113762, 2024 Feb 27.
Artigo em Inglês | MEDLINE | ID: mdl-38341856

RESUMO

In the mammalian cortex, even simple sensory inputs or movements activate many neurons, with each neuron responding variably to repeated stimuli-a phenomenon known as trial-by-trial variability. Understanding the spatial patterns and dynamics of this variability is challenging. Using cellular 2-photon imaging, we study visual and auditory responses in the primary cortices of awake mice. We focus on how individual neurons' responses differed from the overall population. We find consistent spatial correlations in these differences that are unique to each trial and linearly scale with the cortical area observed, a characteristic of critical dynamics as confirmed in our neuronal simulations. Using chronic multi-electrode recordings, we observe similar scaling in the prefrontal and premotor cortex of non-human primates during self-initiated and visually cued motor tasks. These results suggest that trial-by-trial variability, rather than being random noise, reflects a critical, fluctuation-dominated state in the cortex, supporting the brain's efficiency in processing information.


Assuntos
Movimento , Neurônios , Camundongos , Animais , Neurônios/fisiologia , Vigília , Mamíferos
13.
Behav Sci (Basel) ; 14(2)2024 Feb 03.
Artigo em Inglês | MEDLINE | ID: mdl-38392466

RESUMO

This research aims to explore the spatiotemporal distribution patterns of negative emotions in mainland China during different stages of the COVID-19 pandemic and the external factors influencing this clustering. Using Baidu Index data for 91 negative emotion keywords, a retrospective geographic analysis was conducted across Chinese provinces from 14 October 2019 to 7 July 2022. Four spatial analysis methods (Global Moran's Index, Local Moran's Index, Bivariate Global Moran's Index, and Bivariate Local Moran's Index) are employed to identify potential clustering patterns and influencing factors of negative emotions at different stages. The results indicate that the COVID-19 pandemic significantly intensified the clustering effect of negative emotions in China, particularly with a more pronounced radiation effect in northwestern provinces. Spatial positive correlations are observed between pandemic-related Baidu indices (pandemic Baidu index, government Baidu index, nucleic acid Baidu index) and negative emotions. These findings contribute to understanding the spatiotemporal distribution characteristics of negative emotions in China post the COVID-19 outbreak and can guide the allocation of psychological resources during emergencies, thereby promoting social stability.

14.
Environ Monit Assess ; 196(3): 296, 2024 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-38386149

RESUMO

Methane is a significant greenhouse gas (GHG), and it is imperative to understand its spatiotemporal distribution and primary sources in areas with higher methane concentrations, as such insights are essential for informing effective mitigation policies. In this study, we employed TROPOMI satellite retrievals to analyze the spatiotemporal patterns of methane distributions and identify major emission sources in South Korea over the period from August 2018 to July 2019. Additionally, we examined the spatial correlations between satellite methane retrievals and emission sources to characterize regions with higher methane levels on an annual basis.Concerning spatial distributions, concentrations exceeding 1870 ppb were predominantly observed in western non-mountainous regions, particularly in rice paddy areas. Moreover, sporadic concentrations exceeding 1880 ppb were detected in large ports and industrial zones, primarily located in coastal regions of South Korea.Our spatial correlation analysis, conducted using the SDMSelect method, identified specific emissions contributing to regions with higher methane concentrations. There were some areas with relatively strong correlations between high XCH4 and emissions from the domestic livestock industry, fossil fuel utilization (specifically, the oil and gas sector), landfills, and rice paddies. This analysis, incorporating domestic emission inventories and satellite data, provides valuable insights into the characteristics of regional methane concentrations. In addition, this analysis can assess national methane emissions inventories, where there is limited information on the spatial distributions, offering critical information for the prioritization of domestic regional policies aimed at reducing greenhouse gas emissions.


Assuntos
Gases de Efeito Estufa , Oryza , Monitoramento Ambiental , Combustíveis Fósseis , Metano , República da Coreia
15.
Phys Med Biol ; 69(7)2024 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-38354420

RESUMO

Objective.The accurate automatic segmentation of tumors from computed tomography (CT) volumes facilitates early diagnosis and treatment of patients. A significant challenge in tumor segmentation is the integration of the spatial correlations among multiple parts of a CT volume and the context relationship across multiple channels.Approach.We proposed a mutually enhanced multi-view information model (MEMI) to propagate and fuse the spatial correlations and the context relationship and then apply it to lung tumor CT segmentation. First, a feature map was obtained from segmentation backbone encoder, which contained many image region nodes. An attention mechanism from the region node perspective was presented to determine the impact of all the other nodes on a specific node and enhance the node attribute embedding. A gated convolution-based strategy was also designed to integrate the enhanced attributes and the original node features. Second, transformer across multiple channels was constructed to integrate the channel context relationship. Finally, since the encoded node attributes from the gated convolution view and those from the channel transformer view were complementary, an interaction attention mechanism was proposed to propagate the mutual information among the multiple views.Main results.The segmentation performance was evaluated on both public lung tumor dataset and private dataset collected from a hospital. The experimental results demonstrated that MEMI was superior to other compared segmentation methods. Ablation studies showed the contributions of node correlation learning, channel context relationship learning, and mutual information interaction across multiple views to the improved segmentation performance. Utilizing MEMI on multiple segmentation backbones also demonstrated MEMI's generalization ability.Significance.Our model improved the lung tumor segmentation performance by learning the correlations among multiple region nodes, integrating the channel context relationship, and mutual information enhancement from multiple views.


Assuntos
Neoplasias Pulmonares , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Processamento de Imagem Assistida por Computador
16.
Healthcare (Basel) ; 12(3)2024 Jan 24.
Artigo em Inglês | MEDLINE | ID: mdl-38338191

RESUMO

A spatial survival analysis was performed to identify some of the factors that influence the survival of patients with COVID-19 in the states of Guerrero, México, and Chihuahua. The data that we analyzed correspond to the period from 28 February 2020 to 24 November 2021. A Cox proportional hazards frailty model and a Cox proportional hazards model were fitted. For both models, the estimation of the parameters was carried out using the Bayesian approach. According to the DIC, WAIC, and LPML criteria, the spatial model was better. The analysis showed that the spatial effect influences the survival times of patients with COVID-19. The spatial survival analysis also revealed that age, gender, and the presence of comorbidities, which vary between states, and the development of pneumonia increase the risk of death from COVID-19.

17.
Heliyon ; 10(1): e23885, 2024 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-38226282

RESUMO

The quantified measurement and comprehensive analysis of artificial intelligence development (AIDEV) are vital for countries to form AI industrial ecology and promote the long-term development of regional AI technology. Based on the innovation ecosystems (IE) theory, this paper constructs an evaluation system to measure and analyze the spatiotemporal distribution and dynamic evolution of the AIDEV in China from 2011 to 2020. The results show that the AIDEV of China presents an overall upward trend and an obvious unbalance in the spatial distribution which is "eastern > central > western". Meanwhile, the provinces of low-level AIDEV are catching up with the high-level provinces, which leads to the regional difference of AIDEV narrowing. Moreover, the concentration and polarization phenomenon of AIDEV in China has been weakening and the AIDEV will continue to increase in the next three years. Further, there is a significantly positive spatial autocorrelation of AIDEV. Finally, high AIDEV provinces will increase the probability of surrounding provinces' AIDEV to develop. This paper expands the research stream in the field of AI research, extends the application scenarios of IE theory, and puts forward some relevant policy recommendations.

18.
Comput Biol Med ; 169: 107947, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38211385

RESUMO

Pulmonary fibrosis (PF) is a severe and progressive condition in which the lung becomes scarred over time resulting in pulmonary function impairment. Classical histopathology remains an important tool for micro-structural tissue assessment in the diagnosis of PF. A novel workflow based on spatial correlated propagation-based phase-contrast micro computed tomography (PBI-microCT), atomic force microscopy (AFM) and histopathology was developed and applied to two different preclinical mouse models of PF - the commonly used and well characterized Bleomycin-induced PF and a novel mouse model for progressive PF caused by conditional Nedd4-2 KO. The aim was to integrate structural and mechanical features from hallmarks of fibrotic lung tissue remodeling. PBI-microCT was used to assess structural alteration in whole fixed and paraffin embedded lungs, allowing for identification of fibrotic foci within the 3D context of the entire organ and facilitating targeted microtome sectioning of planes of interest for subsequent histopathology. Subsequently, these sections of interest were subjected to AFM to assess changes in the local tissue stiffness of previously identified structures of interest. 3D whole organ analysis showed clear morphological differences in 3D tissue porosity between transient and progressive PF and control lungs. By integrating the results obtained from targeted AFM analysis, it was possible to discriminate between the Bleomycin model and the novel conditional Nedd4-2 KO model using agglomerative cluster analysis. As our workflow for 3D spatial correlation of PBI, targeted histopathology and subsequent AFM is tailored around the standard procedure of formalin-fixed paraffin-embedded (FFPE) tissue specimens, it may be a powerful tool for the comprehensive tissue assessment beyond the scope of PF and preclinical research.


Assuntos
Fibrose Pulmonar , Animais , Camundongos , Fibrose Pulmonar/patologia , Microtomografia por Raio-X/métodos , Microscopia de Força Atômica , Pulmão/anatomia & histologia , Bleomicina
19.
Environ Sci Pollut Res Int ; 31(7): 11178-11191, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38217805

RESUMO

As logistics carbon emission efficiency is an essential industry linking regions, investigating this issue from a spatial correlation perspective is practically significant. Utilizing data from 282 prefecture-level cities spanning 2006 to 2019, we used a super slacks-based measure model, a modified gravity model, motif analysis, the Infomap algorithm, and an exponential random graph model to analyze the spatial correlation patterns and influencing factors of logistics carbon emission efficiency. The following conclusions were drawn. (1) The spatial correlation of logistics carbon emission efficiency during the study period exhibited a core-edge pattern, with the central region emerging as a high-correlation hub. (2) The scale of the spatial association network community of carbon emission efficiency in the logistics industry changed constantly, and the stability of the network community structure gradually increased. From a microstructural perspective, the dispersed-mode structure was a pivotal element in the formation of the spatial correlation network of logistics carbon emission efficiency. (3) Node interaction tendencies were a critical force driving network formation. Financial investment, government concern, international openness, population density, and innovation ability were conducive to the formation of spatial correlations of logistics carbon emission efficiency.


Assuntos
Algoritmos , Carbono , China , Cidades , Governo , Desenvolvimento Econômico
20.
J Environ Manage ; 351: 119564, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38042085

RESUMO

Household consumption carbon emissions (HCCEs) have become the main growth point of China's carbon emissions in the future. It is important to investigate the factors affecting the demand-side carbon emissions in order to find the accurate entry point of emission reduction and achieve carbon peaking and carbon neutrality goals. Different from previous studies, this study analyzed the spatial and temporal evolution characteristics of provincial HCCEs in China from a spatial perspective by using the Theil index and spatial auto-correlation and explored the key influencing factors and spatial spillover effects of HCCEs in different regions by using an econometric model. The results of the study showed that: (1) Per capita HCCEs increased by 11.90% annually, and the eastern region > northeastern region > western region > central region. (2) There were regional differences in per capita HCCEs, but the decrease was significant at 40.32%. (3) The spatial agglomeration effect of per capita HCCEs was significant, and the hot spots were mainly concentrated in the eastern coastal areas. (4) From the national level, every 1% increase in residents' consumption power would increase HCCEs by 2.489%. Which was the main factor for the growth of HCCEs, while the increase in fixed asset investment would restrain HCCEs. At the regional level, the change in population size significantly increased the HCCEs in the eastern and central regions. While for the western region, a 1% increase in population would reduce the HCCEs by 0.542%. For the eastern and central regions, the degree of aging and the consumption structure of residents could suppress regional HCCEs. However, the consumption structure of residents drove the growth of HCCEs in the western region. For the Northeast region, residents' consumption capacity and cooling degree days were the main factors for the growth of residents' consumption, while fixed asset investment could inhibit the growth of HCCEs.


Assuntos
Dióxido de Carbono , Carbono , Carbono/análise , Dióxido de Carbono/análise , China , Investimentos em Saúde , Desenvolvimento Econômico
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