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1.
Cureus ; 16(7): e65468, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39071073

RESUMO

This review aims to identify the associated attributes of willingness to pay (WTP) for overweight and obesity interventions. A narrative review was conducted by partially adopting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. A non-exhaustive search using a pre-defined strategy and keywords was done on three selected literature databases: Pubmed, Scopus, and Web of Science. The inclusion criteria for the review were original studies written in English, published between 2000 and 2022, and focused on WTP for overweight and obesity interventions in adults. The extracted studies were manually screened for their eligibility through three cascading tiers: the title, the abstract, and the full article. Only nine original studies were eligible for review based on the screening procedure of 40 screened articles. There was heterogeneity in the study designs, methods, target populations, study duration, and perspectives across the studies. The majority of the studies showed that higher WTP was associated with younger age, having higher income, being female, having higher body mass index (BMI), having the perception of being overweight, habits, and attitudes. WTP is also attributed to the associated percentage of weight loss, long-term health risk reduction, time to noticeable weight loss, delivery mode, side effects, lifestyle modification, and costs of interventions. The identification of common attributes of the WTP for overweight and obesity intervention can assist in the formulation and implementation of effective evidence-based policies. Specific sub-groups with low WTP could be targeted via unique initiatives to improve their participation in weight-loss interventions.

2.
J Environ Manage ; 360: 121143, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38772240

RESUMO

Drawing upon an extensive body of valuation literature focused on water quality, this paper performs a meta-analysis benefit transfer exercise aimed at quantifying willingness to pay (WTP) for an enhancement in drinking water quality for households that have been directly exposed to Perfluoroalkyl Substances (PFAS) over recent decades in Italy. The analysis compiles metadata of 72 WTP estimates extracted from 40 previous valuation studies conducted in advanced economies. The benefit transfer is realized estimating a meta regression model (MRM) which includes both study design and socio-economic explanatory variables, according to the Weak Structural Utility Theoretic approach. To determine the most suitable MRM specification, a comparative evaluation of various model configurations is developed exploiting the Least Absolute Shrinkage and Selection Operator (LASSO) selection criterion, and assessing their predictive performances in terms of transfer error and explanatory power. The mean transfer error (MTE) and the adjusted R-squared of the preferred MRM are in line with past published meta-analyses (0.665 and 0.607, respectively). The parameters estimated in the model align with both economic theory and intuition. The benefit transfer process results in an estimated annual WTP of € 250.80 per household for improved drinking water quality in the PFAS-affected area and an aggregated value of social benefits from PFAS decontamination of around € 12 million.


Assuntos
Água Potável , Poluentes Químicos da Água , Qualidade da Água , Poluentes Químicos da Água/análise , Humanos , Itália , Fluorocarbonos/análise
3.
Asian Pac J Cancer Prev ; 25(5): 1725-1735, 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38809645

RESUMO

BACKGROUND: Gastrointestinal (GI) cancer burden in Asia is increasing, and Vietnam is no exception. Assessing the affordability of achieving a quality-adjusted life year (QALY) in gastrointestinal cancer patients Vietnam, as well as identifying predictors of willingness to pay (WTP) per QALY, is crucial to decision-making around medical intervention prioritization and performing medical technology assessments for these cancers. OBJECTIVES: Our study aimed to estimate WTP/QALY gained and associated factors among patients diagnosed with GI cancer at a tertiary hospital in Hue, Vietnam. METHODS: A cross-sectional descriptive study, using contingent valuation methodology was conducted among 231 patients at tertiary hospital in 2022. A double limited dichotomous choice and the EQ-5D-5L were utilised to estimate WTP and QALY, respectively. Quantile regression was applied to determine predictors of WTP/QALY. RESULTS: The mean and median maximum WTP/QALY gained among GI patients was $15,165.6 (42,239.6) and $4,365.6 (IQR: 1,586.5-14,552.0), respectively, which was equal to 3.68 times the 2022 gross domestic product (GDP) per capita in Vietnam.  Additionally, cancer severity was found to have a significant impact  on WTP per QALY gained, with a higher amount identified among patients with earlier stages of GI cancer. Furthermore, living in an urban dwelling and patients' treatment modalities were significantly associated with WTP/QALY. CONCLUSION: Evidence from our study can be used to inform how decision-makers in Vietnam to determine the cost-effectiveness of GI cancer interventions.


Assuntos
Neoplasias Gastrointestinais , Anos de Vida Ajustados por Qualidade de Vida , Centros de Atenção Terciária , Humanos , Neoplasias Gastrointestinais/economia , Neoplasias Gastrointestinais/psicologia , Neoplasias Gastrointestinais/terapia , Masculino , Centros de Atenção Terciária/economia , Feminino , Estudos Transversais , Vietnã , Pessoa de Meia-Idade , Idoso , Análise Custo-Benefício , Prognóstico , Seguimentos , Qualidade de Vida , Adulto
4.
Front Psychol ; 15: 1359007, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38737958

RESUMO

Accurately estimating consumers' willingness-to-pay (WTP) is crucial to product design, pricing decisions, and the design of competitive marketing strategies. However, traditional self-report measures of WTP are susceptible to many reporting biases, including tactical responding or an inability to make accurate estimates. Importantly, appraisals also occur automatically (i.e., in the absence of substantial time, intention, awareness, and/or substantial cognitive resources) and implicit measures used to capture automatic appraisals are less susceptible to the sort of reporting biases that self-report measures can be affected by. However, the only existing implicit measure for assessing automatic price appraisals (the Task Rule Congruency paradigm, 'TRC') is impractical because of the large number of trials and time it requires. Accordingly, here we introduce the Implicit Attribute Classification Task (IMPACT), test its effectiveness for the measurement of automatic price appraisals (Study 1), and directly compare its effectiveness and utility with that of the TRC (Study 2). We find that the IMPACT is an efficient measure of automatic price appraisals, that it produces considerably larger effects compared to the TRC, and that it does so while substantially shortening the procedure. We also discuss how the IMPACT scores can be used to derive an implicit measure of willingness to pay. Our findings make a substantial contribution to both research and practice by providing an effective tool that facilitates, for the first time, an efficient exploration of implicit WTP.

5.
Environ Manage ; 74(3): 490-504, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38578325

RESUMO

This study designs a double-bounded dichotomous questionnaire, and uses the Contingent Valuation Method (CVM) to estimate residents' willingness to pay(WTP) for water pollution control along the Taihu Lake Basin. The results of the returned questionnaire show that 82.76% of the residents are willing to pay. CVM estimation results show that the average WTP of residents for water pollution control is 138.86 yuan/year. In addition, the influencing factors of WTP are explored using a Logistic regression model, and the heterogeneity of WTP among residents of different genders is analyzed. The study found that: (1) The younger the residents, the higher their WTP; (2) The higher the income, the higher the residents' WTP for water pollution control; (3) Residents with higher educational level are more willing to pay; (4) The higher the degree of residents' understanding of water pollution control policies, the higher the WTP; (5) The higher the degree of residents' recognition of pro-environmental behavior, the higher the WTP; (6) Male residents' WTP is mainly affected by cognitive factors such as their understanding of governance policies and their approval of pro-environmental behaviors, while female residents' WTP is mainly affected by personal attributes, such as age, income, and the number of household laborers. Furthermore, this study proposes targeted measures to improve residents' WTP from three aspects: the government enriches the channels for residents to participate in water pollution control, the social media enriches the popularization of water environment knowledge, and the school strengthens the education of environmental protection knowledge, considering the differences in residents' characteristics. Therefore, this study can provide a theoretical reference and decision-making basis for encouraging residents to participate in water pollution control, promote the construction of a beautiful watershed, and provide a reference for other basins.


Assuntos
Poluição da Água , Humanos , Masculino , Feminino , China , Poluição da Água/prevenção & controle , Poluição da Água/estatística & dados numéricos , Adulto , Pessoa de Meia-Idade , Inquéritos e Questionários , Lagos , Purificação da Água/métodos , Purificação da Água/economia , Adulto Jovem , Idoso , Fatores Socioeconômicos
6.
Isr J Health Policy Res ; 13(1): 9, 2024 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-38374060

RESUMO

BACKGROUND: mRNA technology is currently being investigated for a range of oncology indications. We assessed the willingness to pay (WTP) of the general population in Israel for a hypothetical novel mRNA-based treatment for oncology indications. METHODS: We used a contingent valuation methodology to elicit WTP using a web-based questionnaire. A sample of adult participants were presented with a hypothetical scenario in which an mRNA-based intervention increased the likelihood of a cure for various cancer types from 20% to 40% (half of the sample), or 60% (the other half of the sample). RESULTS: 531 respondents completed the questionnaire. The mean, median and mode WTP for the proposed hypothetical treatment in both scenarios were ILS65,000 (± ILS114,000), ILS20,000 and ILS50,000, respectively (1USD = 3.4ILS). The WTP was skewed towards zero, and 9.6% of the respondents were not willing to pay any amount. WTP higher amounts was significantly associated with higher income (p < 0.01), self-reported good health (p < 0.05), supplementary health insurance (p < 0.05), Jews compared to other populations (p < 0.01), interest in technology (p < 0.001) and a tendency to adopt medical innovations (p < 0.001). No statistical difference between the 40% vs. the 60% potential cure scenarios was found. Logistic and OLS regressions indicated that age, religion, income, and interest in adopting medical innovations were the best predictors of respondents' WTP. CONCLUSION: Despite the scientific breakthroughs in oncology treatment over the last few decades, many types of cancer are still incurable. Given the expected development of innovative mRNA-based treatments for cancer, these results should inform policymakers, the pharmaceutical industry and other stakeholders on the future coverage and reimbursement of these technologies incorporating patients' and societal views. To date, WTP considerations have not been given much weight in prioritization of drug reimbursement processes, neither in Israel nor in other countries. As a pioneer in adoption of the mRNA technology, Israel can also lead the incorporation of WTP considerations in this field.


Assuntos
Renda , Neoplasias , Adulto , Humanos , Israel , Neoplasias/terapia , Seguro Saúde , Inquéritos e Questionários
7.
J Prev (2022) ; 45(1): 47-85, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37999883

RESUMO

Despite concerted efforts to enforce smoke-free laws in various countries, nonsmokers, particularly women and children, continue to be exposed to daily secondhand smoke (SHS), resulting in significant health risks. While existing studies have assessed the health effects of numerous diseases, the quantification of SHS spillovers remains understudied. This research employs choice experiments and contingent valuation techniques to rigorously quantify the attributes of SHS health risks, with a specific emphasis on facilitating cross-country comparisons. Our investigation reveals that nonsmoking individuals in the United Kingdom exhibit an attitude of indifference towards a proposed policy offering increased disposable income as compensation for SHS exposure. Conversely, nonsmoking Americans express a contrary perspective. Furthermore, our study demonstrates that nonsmoking Americans attribute a higher value to SHS health risks compared to their British counterparts. Consequently, this research uncovers a hitherto unexplored dimension of health risk-related behaviors. These findings hold the potential to significantly contribute to the development of future smoke-free policies, offering valuable insights that can inform policy decisions and address the persistent challenges associated with SHS exposure, particularly among vulnerable populations.


Assuntos
Política Antifumo , Poluição por Fumaça de Tabaco , Criança , Humanos , Feminino , Estados Unidos/epidemiologia , Poluição por Fumaça de Tabaco/efeitos adversos , não Fumantes , Emprego , Brancos
8.
Iran J Pharm Res ; 22(1): e132736, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38116550

RESUMO

Background: Community pharmacists play an important role in improving outcome by providing advice and counselling services to patients. Objectives: The aim of this study was to measure the willingness to pay (WTP) for pharmacist counselling services in community pharmacies and identify determinant factors on consumers' WTP. Methods: A self-administered questionnaire-based survey was conducted in community pharmacies in Tehran (capital of Iran) from January 1, 2020 to February 20, 2021. Contingent valuation method was applied to evaluate respondents' maximum WTP using three hypothetical scenarios illustrating different levels of counselling services. Logistic regression was used to analyze the association between different variables and WTP for pharmacy services. Results: Total number of participants who completed the questionnaire were 332 and 60% of the participants were male. In the first scenario 70.2% of participants were willing to pay for oral counselling pharmacy services. In the second and third scenario, percentage of people willing to pay increased to 79.5%. and 86.1%, respectively. In the first scenario, monthly income (OR = 0.041, P value = 0.04), the duration of underlying illness (OR = 0.04, P value = 0.04) and the using internet (OR = 2.59, P value = 2.59) had a statistically significant relationship with willingness to pay. In the third scenario, the willingness to pay increased as the age decreased. The possibility of using the internet (OR = 3.32, P value = 0.00) and the need for a community pharmacist (OR = 2.19, P value = 0.03) increased the chance of willingness to pay. Conclusions: More consumers are willing to pay for more pharmacist counselling services. Therefore, improving the quality of counselling services could have positive economic effects on community pharmacies.

9.
BMC Health Serv Res ; 23(1): 1196, 2023 Nov 02.
Artigo em Inglês | MEDLINE | ID: mdl-37919709

RESUMO

BACKGROUND: Since the introduction of fee-for-service models in public hospitals and the legalization of private health services in Vietnam in 1989, the price of reproductive health services has risen. These changes have exacerbated inequities in accessing reproductive health services. This study examines potential disparities in willingness to pay for reproductive health services among adults in a rural district of Hanoi. METHODS: A cross-sectional study was conducted at 9 communes in Thanh Oai district, a rural district of Hanoi, Vietnam, in July 2019. Face-to-face interviews were conducted using a structured questionnaire to collect self-reported data. The contingent valuation was used to examine willingness to pay for reproductive health services with a starting price of 2 million VND (~ US$86.2, July 2019 exchange rate), which is the average price of all RHS in public facilities in Vietnam. Multiple Logistic regression and Multiple Interval regression models were used to identify factors associated with willingness to pay and the amount that people were willing to pay for reproductive health services. RESULTS: Among 883 participants, this study found 59.1% of them willing to pay for reproductive health services at an average maximum amount of US$36.2, significantly less than the current average price of US$86.2. Occupation, number of sex partners, perception towards the necessity of reproductive health services, and prior use of reproductive health services were found to significantly influence willingness to pay for reproductive health services, while age, income level, gender, occupation, perception towards the necessity of reproductive health services and prior use of reproductive health services were reportedly correlated with the amount participants were willing to pay for reproductive health services. CONCLUSION: Lower willingness to pay for reproductive health services compared to the current prices (US$36.2 vs. US$86.2) is likely related to an overall low awareness of the necessity of reproductive health services, and future education campaigns should specifically target those from lower-income backgrounds. Financial subsidization should also be provided, especially for those from the low-income group, to ensure equitable access to reproductive health services. Given the heterogeneity of reproductive health services, further studies should examine the willingness to pay for each type of service independently.


Assuntos
Países em Desenvolvimento , Renda , Humanos , Adulto , Estudos Transversais , Vietnã , Inquéritos e Questionários
10.
Eur J Health Econ ; 2023 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-37656261

RESUMO

BACKGROUND: The value of a Quality-Adjusted Life-Year (QALY) is of great importance for the healthcare system. It helps when it comes to defining a cost-effectiveness threshold for the evaluation of health technologies. No willingness-to-pay value for a QALY exists in the province of Quebec, Canada. OBJECTIVES: In this paper, we empirically investigated the monetary value of a QALY for the population of Quebec. METHODS: Based on the Short-Form 6-Dimension version 2 (SF-6Dv2), we conducted an online survey with a representative adult sample living in Quebec. We used a time trade-off (TTO) combined with contingent valuation (CV), and a discrete choice experiment (DCE) to assess both the population's willingness to pay (WTP) for one QALY and the marginal WTP for health attributes. A health utility algorithm using hybrid regression was developed to determine a preference-based value set for health states. RESULTS: Main analysis was conducted on 993 answers for the CV and 2143 answers for the DCE. The willingness-to-pay per QALY varied from CA$ 47,048.84 (CI: 21,554.38; 72,543.30) for CV to CA$ 73,936.87 (CI: 63,105.40; 84,768.35) for DCE. Among the 6 dimensions of the SF-6Dv2, marginal WTP varied from CA$ 4499.15 (CI: 2975.06; 6023.25) for more role accomplishment in daily activities to CA$ 15,867.12 (CI: 13,825.75; 17,908.49) for less pain. Robustness check with multiple alternative samples, as well as alternative health utility algorithms, showed that the results were robust and the DCE method provided 50% larger results than the CV method, although confidence intervals overlap. CONCLUSION: This paper provides useful information for decision-makers on the monetary value of a QALY in Quebec.

11.
J Environ Manage ; 345: 118806, 2023 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-37619384

RESUMO

Promotion of energy-saving household appliances (ESHAs) potentially contributes to optimizing both the total quantity and efficiency of household energy consumption. Differences in urban consumers' preference for higher-grade ESHAs as well as its influencing factors in cities with hierarchical socioeconomic levels remain elusive. Targeting 55 Chinese cities pertaining to three levels of socioeconomic development, we distribute questionnaires designed to cover both demographic and consciousness factors. By combining Contingent Valuation Method and multiple linear regression, the extra willingness to pay (WTP) for Grade-1/2 appliances compared with Grade-3 appliances is measured, and the influence factors on the WTP as well as consumers with highest WTP are identified. The extra WTP for Grade-1 appliances in First-, Second- and Third-level cities is 44.1%, 42.3% and 32.7%, respectively. The influences of age, household income, having children or not and monthly electricity bill parallel the socioeconomic level, while gender and schooling affect differently across socioeconomic levels. Consumers in less developed cities focus more on their affordability for the ESHAs, and in more developed cities have better environmental consciousness. Subsidies for consumers, such as those having master degree or above in First-level and Second-level cities, and having children in Third-level cities will increase their WTP. The findings provide insights for policy interventions aimed at boosting the purchase behavior for ESHAs according to local conditions for control of both household energy consumption and carbon emissions.


Assuntos
Comportamento do Consumidor , Classe Social , Cidades , Análise Multivariada , Inquéritos e Questionários , China
12.
J Hazard Mater ; 459: 132206, 2023 10 05.
Artigo em Inglês | MEDLINE | ID: mdl-37543018

RESUMO

Despite the significant attention given to microplastics in urban areas, our understanding of microplastics in rural drinking water systems is still limited. To address this knowledge gap, we investigated the presence and pathways of microplastics in rural drinking water system, including reservoir, water treatment plant (WTP), and tap water of end-users. The results showed that the treatment processes in the WTP, including coagulation-sedimentation, sand-granular active carbon filtration, and ultrafiltration, completely removed microplastics from the influent. However, the microplastic abundance increased during pipe transport from WTP to residents' homes, resulting in the presence of 1.4 particles/L of microplastics in tap water. This microplastic increase was also observed during the transportation from the reservoir to the WTP, suggesting that the plastic pipe network is a key source of microplastics in the drinking water system. The main types of polymers were PET, PP, and PE, and plastic breakdown, atmospheric deposition, and surface runoff were considered as their potential sources. Furthermore, this study estimated that rural residents could ingest up to 1034 microplastics annually by drinking 2 L of tap water every day. Overall, these findings provide essential data and preliminary insights into the fate of microplastics in rural drinking water systems.


Assuntos
Água Potável , Poluentes Químicos da Água , Microplásticos , Plásticos , Poluentes Químicos da Água/análise , Monitoramento Ambiental , China
13.
Front Public Health ; 11: 1058026, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37475766

RESUMO

Background: The prevention of disease burden and death through vaccination is one of the most cost-effective methods. Even though the Hepatitis B Virus (HBV) has significant public health problems in Ethiopia, there is no compulsory HBV vaccination program for adults and the vaccine's market value was not yet estimated in the Ethiopia context. Therefore, this study aimed to assess the willingness to pay (WTP) for the HBV vaccine and its associated factors among households in Bahir Dar City, northwest Ethiopia. Methods: A cross-sectional study was conducted among 620 households from March 1 to 30, 2020. A systematic random sampling technique was employed to select the required number of households. An interviewer-administered questionnaire was used to collect the necessary information. The contingent valuation method was conducted to measure WTP for the HBV vaccine. A Tobit regression model was employed to investigate significantly associated factors, and variables with a p-value of <0.05 were considered statistically significant. Results: In this study, 62.17% of households were willing to pay for the HBV vaccine with an average cost of ETB174.24 (US$5.25). Male household heads (P = 0.014), favorable attitude (P = 0.017), and good knowledge (P < 0.001) toward the vaccine were positively associated with WTP, whereas age (P < 0.001), single marital status (P = 0.012) and divorced/widowed (P = 0.018) marital status were negatively associated with WTP. Conclusions: Overall, most households were willing to pay for the HBV vaccine with an average demand of ETB174.24 (US$5.25). Therefore, a national-level HBV vaccine strategy should be designed considering the households' willingness to pay. In addition, working on attitudes and knowledge toward the vaccine could potentially increase the household's willingness to pay for the HBV vaccine.


Assuntos
Vacinas contra Hepatite B , Vírus da Hepatite B , Masculino , Humanos , Etiópia , Estudos Transversais , Características da Família
14.
Cancers (Basel) ; 15(14)2023 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-37509366

RESUMO

Purpose: To investigate the immune biomarker in Leiomyosarcoma (LMS), which is rare and recognized as an immune cold cancer showing a poor response rate (<10%) to immune checkpoint inhibitors (ICIs). However, durable response and clinical benefit to ICIs has been observed in a few cases of LMS, including, but not only, LMS with tertiary lymphoid structure (TLS) structures. Patients and methods: We used comprehensive transcriptomic profiling and a deconvolution method extracted from RNA-sequencing gene expression data in two independent LMS cohorts, the International Cancer Genome Consortium (ICGC, N = 146) and The Cancer Genome Atlas (TCGA, N = 75), to explore tumor immune microenvironment (TIME) in LMS. Results: Unsupervised clustering analysis using the previously validated two methods, 90-gene signature and Cell-type Identification by Estimating Relative Subsets of RNA Transcripts (CIBERSORT), identified immune hot (I-H) and immune high (I-Hi) LMS, respectively, in the ICGC cohort. Similarly, immune active groups (T-H, T-Hi) were identified in the TCGA cohort using these two methods. These immune active ("hot") clusters were significantly associated, but not completely overlapping, with several validated immune signatures such as sarcoma immune class (SIC) classification and TLS score, T cell inflamed signature (TIS) score, immune infiltration score (IIS), and macrophage score (M1/M2), with more patients identified by our clustering as potentially immune hot. Conclusions: Comprehensive immune profiling revealed a subset of LMS with a distinct active ("hot") TIME, consistently associated with several validated immune signatures in other cancers. This suggests that the methodologies that we used in this study warrant further validation and development, which can potentially help refine our current immune biomarkers to select the right LMS patients for ICIs in clinical trials.

15.
BMC Public Health ; 23(1): 667, 2023 04 11.
Artigo em Inglês | MEDLINE | ID: mdl-37041634

RESUMO

BACKGROUND: About 5-10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women's subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants. METHODS: An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables. RESULTS: 660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP. CONCLUSIONS: Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help.


Assuntos
Neoplasias da Mama , Humanos , Feminino , Adulto , Irã (Geográfico) , Detecção Precoce de Câncer , Renda , Modelos Logísticos
16.
Front Glob Womens Health ; 4: 971553, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36937042

RESUMO

Background: Using traditional health technology assessment (HTA) outcome metrics, such as quality-adjusted life-years, to assess fertility treatments raises considerable methodological challenges because the objective of fertility treatments is to create new life rather than extend, save, or improve health-related quality of life. Objective: The aim of this study was to develop a novel cost-benefit framework to assess value for money of publicly funded IVF treatment; to determine the number of cost-beneficial treatment cycles for women of different ages; and to perform an incremental cost-benefit analysis from a taxpayer perspective. Methods: We developed a Markov model to determine the net monetary benefit (NMB) of IVF treatment by female age and number of cycles performed. IVF treatment outcomes were monetized using taxpayers' willingness-to-pay values derived from a discrete choice experiment (DCE). Using the current funding environment as the comparator, we performed an incremental analysis of only funding cost-beneficial cycles. Similar outputs to cost-effectiveness analyses were generated, including net-benefit acceptability curves and cost-benefit planes. We created an interactive online app to provide a detailed and transparent presentation of the results. Results: The results suggest that at least five publicly funded IVF cycles are cost-beneficial in women aged <42 years. Cost-benefit planes suggest a strong taxpayer preference for restricting funding to cost-beneficial cycles over current funding arrangements in Australia from an economic perspective. Conclusions: The provision of fertility treatment is valued highly by taxpayers. This novel cost-benefit method overcomes several challenges of conventional cost-effectiveness methods and provides an exemplar for incorporating DCE results into HTA. The results offer new evidence to inform discussions about treatment funding arrangements.

17.
Nanomaterials (Basel) ; 13(6)2023 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-36985909

RESUMO

The existence of heavy metals and organic pollutants in wastewater is a threat to the ecosystem and a challenge for researchers to remove using common technology. Herein, a facile one-step in situ oxidative polymerization synthesis method has been used to fabricate polyaniline@waste cellulosic nanocomposite adsornt, polyaniline-embedded waste tissue paper (PANI@WTP) to remove copper(II) and phenol from the aqueous solution. The structural and surface properties of the synthesized materials were examined by XRD, FTIR, TEM, and a zeta potential analyzer. The scavenging of the Cu(II) and phenol onto the prepared materials was investigated as a function of interaction time, pollutant concentration, and solution pH. Advanced kinetics and isotherms modeling is used to explore the Cu(II) ion and phenol adsorption mechanisms. The synthesized PANI@WTP adsorbent showed a high intake capacity for Cu(II) than phenol, with the maximum calculated adsorption capacity of 605.20 and 501.23 mg g-1, respectively. The Langmuir equilibrium isotherm model is well-fitted for Cu(II) and phenol adsorption onto the PANI@WTP. The superior scavenging capability of the PANI@WTP for Cu(II) and phenol could be explained based on the host-guest interaction forces and large active sites. Moreover, the efficiency of the PANI@WTP for Cu(II) and phenol scavenging was excellent even after the five cycles of regeneration.

18.
Waste Manag ; 163: 22-33, 2023 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-36989827

RESUMO

Efficient Waste Management Systems (WMS) depend on citizens' willingness to sort waste and to cooperate for its improved provision. Thus, it is essential to understand what attributes individuals value the most and what drives WMS preference heterogeneity. In this paper, we investigate how individuals evaluate WMS attributes (e.g., the number of waste sorting categories, the introduction of textile sorting, and the frequency of collection per week) and how the local contexts, socioeconomics, and environmental values shape their preferences. For this purpose, we conducted a discrete choice experiment on a sample representative of the Italian population interviewed through an online panel survey. We collected information on individual's preferences for WMS attributes, environmental awareness, and socioeconomic characteristics. We analyzed the data using hybrid mixed choice models, which allowed us to integrate environmental awareness values into willingness to pay estimations. We found that individuals are willing to pay for waste sorting, even if this implies more effort on their part and increased storage space. In addition, we found that the extent to which individuals support WMS improvements strongly depends on their environmental values, experiences (which are shaped by their local context), and socioeconomic factors. Our results suggest that to increase recycling rates and citizen satisfaction, there is a need for context-specific WMS designs that acknowledge the observed heterogeneity of preferences.


Assuntos
Características da Família , Gerenciamento de Resíduos , Humanos , Fatores Socioeconômicos , Inquéritos e Questionários
19.
Artigo em Inglês | MEDLINE | ID: mdl-36767551

RESUMO

The purpose of this study was to note how people recognize the green lifestyle and how much extra money they are willing to pay for it. An integrated model based on the theory of planned behavior was constructed, and data on the willingness to pay (WTP) for green lifestyles of 1377 respondents in five cities in East China were measured and calculated using the double-bounded dichotomous choice contingent valuation method (DBDC) combined with interval regression analysis. The results showed that the respondents were willing to pay an extra 81.8 yuan, 52.5 yuan, 38.9 yuan, 53.2 yuan, and 37.2 yuan per month for green food, clothing, travel, housing, and waste recycling, respectively. Attitude and moral norms were the strongest predictors of WTP for green clothing, travel, housing, and waste recycling. Perceived behavior control, environmental awareness, personal habits, subjective knowledge, gender, income, and education can affect a few kinds of green lifestyle's WTP.


Assuntos
Atitude , Princípios Morais , Humanos , China , Renda , Escolaridade , Inquéritos e Questionários
20.
Environ Manage ; 72(2): 262-274, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-36653481

RESUMO

The soaring economic development of export activities of handicrafts centralized in emerging urban regions in Vietnam has accelerated the increase in the occurrence of diseases and threats to ecosystems induced by water pollution. We design a discrete choice experiment to elicit the willingness-to-pay of handicraft enterprises to restore the environment and diminish health risks from polluted wastewater through water quality improvement under different scenarios. Estimates from five latent classes reveal that one-half of entrepreneurs strongly value the provision of wastewater treatment services, and their decisions are mostly driven by preferences to reduce the risk of sickness caused by water pollution. This finding lends support to the argument that self-interested preferences predominate pro-environmental behavior in the readiness to pay for water quality services. While entrepreneurs' preferences attributed to ecological remediation seem to vary according to their educational background, the status-quo group shows low environmental awareness. This divergent behavioral pattern suggests that the design of wastewater management policies requires a mixture of measures that aim at different groups of individuals pursuing economic incentives and the creation of awareness.


Assuntos
Conservação dos Recursos Naturais , Ecossistema , Humanos , Vietnã , Águas Residuárias , Poluição da Água/prevenção & controle
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