Prevalence of irritable bowel syndrome and other functional gastrointestinal disorders in Uruguay.

INTRODUCTION AND AIMS: Irritable bowel syndrome (IBS) is one of the most frequent functional gastrointestinal disorders. Prevalence worldwide is estimated at 11%. There is little information on the prevalence of the other functional bowel disorders (FBDs). Our aim was to establish the prevalence of IBS and other FBDs according to the Rome IV criteria, in Uruguay. MATERIALS AND METHODS: An observational, population-based prevalence study was conducted. Data were collected through an online questionnaire, utilizing the Rome IV criteria. RESULTS: Of the 1,052 participants (79% women, mean patient age 44 years), 47.2% met the Rome IV diagnostic criteria for at least one of the FBDs analyzed. Functional constipation (FC) was the most frequent, at 18.7% (16.4-21.1), followed by IBS at 17.1% (14.9-19.4) and functional diarrhea (FD) at 15.4% (13.3-17.6). IBS with constipation (IBS-C) was the most frequent IBS subtype (35%) and the IBS with diarrhea (IBS-D) subtype predominated in men. All FBDs were more prevalent in women and youths. Of the survey participants with a FBD, 59% stated that they perceived no worsening of their symptoms related to the COVID-19 pandemic. CONCLUSIONS: Ours is the first prevalence study on FBDs conducted on the Uruguayan general population. Half of the participants surveyed presented with a FBD analyzed in the study. FC was the most frequent, followed by IBS and FD. The prevalence rate of IBS was the highest, based on the Rome IV diagnostic criteria, and constipation was the most frequent subtype.

Neonatal Antibiotics and Prematurity Are Associated with an Increased Risk of Functional Gastrointestinal Disorders in the First Year of Life.

OBJECTIVE: To assess the prevalence of functional gastrointestinal disorders (FGIDs) in the first year of life and the influence of different neonatal factors on development of FGIDs. STUDY DESIGN: A prospective cohort multicenter study including neonates, consecutively enrolled at birth, and followed up until 1 year. Gestational age, neonatal antibiotic administration, duration of hospitalization, mode of delivery, birth weight, and feeding pattern were recorded. FGIDs were classified according to Rome III criteria and assessed at 1, 3, 6, and 12 months of life. RESULTS: Among 1152 newborns enrolled, 934 (81.1%) completed the study, 302 (32%) were newborns born preterm, 320 (34%) had neonatal antibiotics, and 718 (76.9%) had at least 1 FGID according to Rome III criteria (443 [47.4%] infantile colic, 374 [40.0%] regurgitation, 297 [31.8%] infant dyschezia, 248 [26.6%] functional constipation, and 34 [3.6%] functional diarrhea) throughout the first year of life. The proportion of infants born preterm presenting with FGIDs (86%) was significantly greater compared with infants born full term (72.5%) (χ2 = 21.3, P = .0001). On multivariate analysis, prematurity and neonatal use of antibiotics was significantly associated with at least 1 FGID. CONCLUSIONS: We found a high rate FGIDs in infants, likely related to the population recruited, the long observation period, the diagnosis based on Rome III criteria, and parental reports. Preterm delivery and neonatal use of antibiotics in the first months of life are associated with an increased incidence of FGIDs, particularly infantile colic and regurgitation. In our population, cesarean delivery and feeding pattern at 1 month of life emerged as additional risk factors for infant dyschezia and functional diarrhea. Other neonatal factors associated with FGIDs need to be further explored.

A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children.

OBJECTIVE: To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. STUDY DESIGN: We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants & Toddlers. RESULTS: Parents of 1231 subjects completed the questionnaires; 48 children were excluded due to presence of organic diseases and being older than 48 months of age. Four hundred eighty children (40.5%) were diagnosed with at least 1 FGID according to the Rome III diagnostic criteria (49% female, median 12 months). Functional constipation was the most commonly diagnosed disorder in infants (up to 12 months of age) and children of ages 13-48 months (16.1% and 26.8%, respectively). Analysis revealed that the prevalence of FGID was significantly greater in children who were the only child in the family (P = .003), children who were first-born (P = .007), and children with divorced or separated parents. (P = .001). CONCLUSIONS: FGIDs are common in children younger than 4 years of age. Functional constipation and infant colic were the most common FGIDs in infants (up to 12 months of age), and functional constipation and rumination were the most common FGIDs in children 13-48 months of age.

Diarreia funcional e síndrome do intestino irritável em crianças / Functional diarrea and the irritable bowel syndrome in childhood

A autora atualiza, de forma prática, os conhecimentos modernos sobre duas patologias frequentes na infância, a diarreia funcional e a síndrome do intestino irritável.O trabalho revê o histórico e a sinonímia das mesmas, trata de sua etiopatogenia, aspectos clínicos e diagnóstico, diagnóstico diferencial e tratamento.No capítulo referente à terapêutica apresenta a conduta atual, tanto dietética como medicamentosa, ressaltando as controvérsias ainda existentes a respeito.

Diarrea funcional como causa de diarrea crónica / Functional diarrhea as cause of chronic diarrhea

La diarrea funcional se presenta con frecuencia en la práctica pediátrica, y generalmente no se asocia a alteraciones nutricionales, pero sí a esquemas dietéticos incorrectos. Se actualiza su importancia clínica, se hace énfasis en la patogenia, diagnóstico y en los métodos de tratamiento. Consideramos que es la causa más frecuente de diarrea crónica inespecífica y que el interrogatorio dirigido según los criterios de Roma es útil para su diagnóstico. La mayoría de los pacientes con esta enfermedad en la infancia deben ser tratados en la atención primaria

The functional diarrhea is frequent in the pediatric practice and in general it is not associated with nutritional alterations, but to incorrect dietary schemes. Its clinical significance is updated and its pathogenesis, diagnosis and treatment methods are emphasized. Authors considered that the functional diarrhea is the more frequent cause of unspecific chronic diarrhea and the questioning directed according the Rome criteria is very useful for its diagnosis. Most of patients presenting with this disease during childhood must to be treated in primary care services

Distúrbios gastrointestinais funcionais da infância e adolescência / Functional gastrointestinal disoders in chilhood and adolescents

Os critérios de Roma foram desenvolvidos para padronizar a classificação dos distúrbios gastrointestinais funcionais de crianças usando como base os sintomas relatados. Os parentes muitas vezes têm importante papel na descrição dos sintomas das crianças. Os critérios de Roma foram estabelecidos por um grupo de especialistas internacionais. Estas informações levarão à melhor compreensão das diferentes apresentações clínicas dos distúrbios funcionais, maior acurácia do diagnóstico e aprimoramento nas investigações e tratamento destas desordens. Os distúrbios gastrointestinais funcionais são: regurgitação infantil, síndrome de ruminação infantil, síndrome dos vômitos cíclicos, dispepsia funcional, síndrome do intestino irritável, dor abdominal funcional, enxaqueca abdominal, aerofagia, diarréia funcional, constipação funcional, disquesia infantil, retenção fecal funcional, escape fecal funcional não retentivo...

The Pediatric Rome Criteria were developed to standardize the classification of functional gastrointestinal disorders of children using a symptom-based approach. The parents often play a large role in reporting their child's symptoms. The Rome Criteria has been established by a multinational team of experts. These intor- mations will lead to a better understanding of the different clinical presentations of functional disorders, more accurate diagnosis, and therefore improve treatment and investigations of the disor- ders. The functional Gastrointestinal disorders are: infant regurgi- tation, infant rumination syndrome, cyclic vomiting syndrome, functional dyspepsia, irritable bowel syndrome, functional abdo- minal pain, abdominal migraine, aerophagia, functional diarrhea, functional constipation, functional fecal retention and non-retentive fecal soiling...