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1.
Heliyon ; 10(12): e32479, 2024 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-39183851

RESUMO

Numerous methods and pipelines have recently emerged for the automatic extraction of knowledge graphs from documents such as scientific publications and patents. However, adapting these methods to incorporate alternative text sources like micro-blogging posts and news has proven challenging as they struggle to model open-domain entities and relations, typically found in these sources. In this paper, we propose an enhanced information extraction pipeline tailored to the extraction of a knowledge graph comprising open-domain entities from micro-blogging posts on social media platforms. Our pipeline leverages dependency parsing and classifies entity relations in an unsupervised manner through hierarchical clustering over word embeddings. We provide a use case on extracting semantic triples from a corpus of 100 thousand tweets about digital transformation and publicly release the generated knowledge graph. On the same dataset, we conduct two experimental evaluations, showing that the system produces triples with precision over 95% and outperforms similar pipelines of around 5% in terms of precision, while generating a comparatively higher number of triples.

2.
BMC Med Inform Decis Mak ; 24(1): 221, 2024 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-39103849

RESUMO

Performing data augmentation in medical named entity recognition (NER) is crucial due to the unique challenges posed by this field. Medical data is characterized by high acquisition costs, specialized terminology, imbalanced distributions, and limited training resources. These factors make achieving high performance in medical NER particularly difficult. Data augmentation methods help to mitigate these issues by generating additional training samples, thus balancing data distribution, enriching the training dataset, and improving model generalization. This paper proposes two data augmentation methods-Contextual Random Replacement based on Word2Vec Augmentation (CRR) and Targeted Entity Random Replacement Augmentation (TER)-aimed at addressing the scarcity and imbalance of data in the medical domain. When combined with a deep learning-based Chinese NER model, these methods can significantly enhance performance and recognition accuracy under limited resources. Experimental results demonstrate that both augmentation methods effectively improve the recognition capability of medical named entities. Specifically, the BERT-BiLSTM-CRF model achieved the highest F1 score of 83.587%, representing a 1.49% increase over the baseline model. This validates the importance and effectiveness of data augmentation in medical NER.


Assuntos
Aprendizado Profundo , Humanos , Processamento de Linguagem Natural
3.
Stud Health Technol Inform ; 316: 1487-1491, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39176485

RESUMO

This article presents our experience in development an ontological model can be used in clinical decision support systems (CDSS) creating. We have used the largest international biomedical terminological metathesaurus the Unified Medical Language System (UMLS) as the basis of our model. This metathesaurus has been adapted into Russian using an automated hybrid translation system with expert control. The product we have created was named as the National Unified Terminological System (NUTS). We have added more than 33 million scientific and clinical relationships between NUTS terms, extracted from the texts of scientific articles and electronic health records. We have also computed weights for each relationship, standardized their values and created symptom checker in preliminary diagnostics based on this. We expect, that the NUTS allow solving task of named entity recognition (NER) and increasing terms interoperability in different CDSS.


Assuntos
Registros Eletrônicos de Saúde , Bases de Conhecimento , Unified Medical Language System , Sistemas de Apoio a Decisões Clínicas , Processamento de Linguagem Natural , Humanos , Federação Russa , Vocabulário Controlado
4.
Stud Health Technol Inform ; 316: 272-276, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39176725

RESUMO

The task of Named Entity Recognition (NER) is central for leveraging the content of clinical texts in observational studies. Indeed, texts contain a large part of the information available in Electronic Health Records (EHRs). However, clinical texts are highly heterogeneous between healthcare services and institutions, between countries and languages, making it hard to predict how existing tools may perform on a particular corpus. We compared four NER approaches on three French corpora and share our benchmarking pipeline in an open and easy-to-reuse manner, using the medkit Python library. We include in our pipelines fine-tuning operations with either one or several of the considered corpora. Our results illustrate the expected superiority of language models over a dictionary-based approach, and question the necessity of refining models already trained on biomedical texts. Beyond benchmarking, we believe sharing reusable and customizable pipelines for comparing fast-evolving Natural Language Processing (NLP) tools is a valuable contribution, since clinical texts themselves can hardly be shared for privacy concerns.


Assuntos
Registros Eletrônicos de Saúde , Processamento de Linguagem Natural , França , Humanos
5.
Stud Health Technol Inform ; 316: 611-615, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39176816

RESUMO

Secure extraction of Personally Identifiable Information (PII) from Electronic Health Records (EHRs) presents significant privacy and security challenges. This study explores the application of Federated Learning (FL) to overcome these challenges within the context of French EHRs. By utilizing a multilingual BERT model in an FL simulation involving 20 hospitals, each represented by a unique medical department or pole, we compared the performance of two setups: individual models, where each hospital uses only its own training and validation data without engaging in the FL process, and federated models, where multiple hospitals collaborate to train a global FL model. Our findings demonstrate that FL models not only preserve data confidentiality but also outperform the individual models. In fact, the Global FL model achieved an F1 score of 75,7%, slightly comparable to that of the Centralized approach at 78,5%. This research underscores the potential of FL in extracting PIIs from EHRs, encouraging its broader adoption in health data analysis.


Assuntos
Segurança Computacional , Confidencialidade , Registros Eletrônicos de Saúde , Aprendizado de Máquina , França , Humanos , Registros de Saúde Pessoal
6.
Stud Health Technol Inform ; 316: 666-670, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39176830

RESUMO

Named Entity Recognition (NER) models based on Transformers have gained prominence for their impressive performance in various languages and domains. This work delves into the often-overlooked aspect of entity-level metrics and exposes significant discrepancies between token and entity-level evaluations. The study utilizes a corpus of synthetic French oncological reports annotated with entities representing oncological morphologies. Four different French BERT-based models are fine-tuned for token classification, and their performance is rigorously assessed at both token and entity-level. In addition to fine-tuning, we evaluate ChatGPT's ability to perform NER through prompt engineering techniques. The findings reveal a notable disparity in model effectiveness when transitioning from token to entity-level metrics, highlighting the importance of comprehensive evaluation methodologies in NER tasks. Furthermore, in comparison to BERT, ChatGPT remains limited when it comes to detecting advanced entities in French.


Assuntos
Processamento de Linguagem Natural , França , Humanos , Registros Eletrônicos de Saúde , Idioma , Neoplasias , Vocabulário Controlado
7.
Heliyon ; 10(12): e32093, 2024 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-38948047

RESUMO

Chinese agricultural named entity recognition (NER) has been studied with supervised learning for many years. However, considering the scarcity of public datasets in the agricultural domain, exploring this task in the few-shot scenario is more practical for real-world demands. In this paper, we propose a novel model named GlyReShot, integrating the knowledge of Chinese character glyph into few-shot NER models. Although the utilization of glyph has been proven successful in supervised models, two challenges still persist in the few-shot setting, i.e., how to obtain glyph representations and when to integrate them into the few-shot model. GlyReShot handles the two challenges by introducing a lightweight glyph representation obtaining module and a training-free label refinement strategy. Specifically, the glyph representations are generated based on the descriptive sentences by filling the predefined template. As most steps come before training, this module aligns well with the few-shot setting. Furthermore, by computing the confidence values for draft predictions, the refinement strategy selectively utilizes the glyph information only when the confidence values are relatively low, thus mitigating the influence of noise. Finally, we annotate a new agricultural NER dataset and the experimental results demonstrate effectiveness of GlyReShot for few-shot Chinese agricultural NER.

8.
Radiol Artif Intell ; 6(5): e230277, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39046325

RESUMO

Purpose To develop a machine learning approach for classifying disease progression in chest radiographs using weak labels automatically derived from radiology reports. Materials and Methods In this retrospective study, a twin neural network was developed to classify anatomy-specific disease progression into four categories: improved, unchanged, worsened, and new. A two-step weakly supervised learning approach was employed, pretraining the model on 243 008 frontal chest radiographs from 63 877 patients (mean age, 51.7 years ± 17.0 [SD]; 34 813 [55%] female) included in the MIMIC-CXR database and fine-tuning it on the subset with progression labels derived from consecutive studies. Model performance was evaluated for six pathologic observations on test datasets of unseen patients from the MIMIC-CXR database. Area under the receiver operating characteristic (AUC) analysis was used to evaluate classification performance. The algorithm is also capable of generating bounding-box predictions to localize areas of new progression. Recall, precision, and mean average precision were used to evaluate the new progression localization. One-tailed paired t tests were used to assess statistical significance. Results The model outperformed most baselines in progression classification, achieving macro AUC scores of 0.72 ± 0.004 for atelectasis, 0.75 ± 0.007 for consolidation, 0.76 ± 0.017 for edema, 0.81 ± 0.006 for effusion, 0.7 ± 0.032 for pneumonia, and 0.69 ± 0.01 for pneumothorax. For new observation localization, the model achieved mean average precision scores of 0.25 ± 0.03 for atelectasis, 0.34 ± 0.03 for consolidation, 0.33 ± 0.03 for edema, and 0.31 ± 0.03 for pneumothorax. Conclusion Disease progression classification models were developed on a large chest radiograph dataset, which can be used to monitor interval changes and detect new pathologic conditions on chest radiographs. Keywords: Prognosis, Unsupervised Learning, Transfer Learning, Convolutional Neural Network (CNN), Emergency Radiology, Named Entity Recognition Supplemental material is available for this article. © RSNA, 2024 See also commentary by Alves and Venkadesh in this issue.


Assuntos
Progressão da Doença , Radiografia Torácica , Aprendizado de Máquina Supervisionado , Humanos , Feminino , Pessoa de Meia-Idade , Estudos Retrospectivos , Masculino , Radiografia Torácica/métodos , Redes Neurais de Computação , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Adulto
9.
JMIR Cancer ; 10: e43070, 2024 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-39037754

RESUMO

BACKGROUND: Commonly offered as supportive care, therapist-led online support groups (OSGs) are a cost-effective way to provide support to individuals affected by cancer. One important indicator of a successful OSG session is group cohesion; however, monitoring group cohesion can be challenging due to the lack of nonverbal cues and in-person interactions in text-based OSGs. The Artificial Intelligence-based Co-Facilitator (AICF) was designed to contextually identify therapeutic outcomes from conversations and produce real-time analytics. OBJECTIVE: The aim of this study was to develop a method to train and evaluate AICF's capacity to monitor group cohesion. METHODS: AICF used a text classification approach to extract the mentions of group cohesion within conversations. A sample of data was annotated by human scorers, which was used as the training data to build the classification model. The annotations were further supported by finding contextually similar group cohesion expressions using word embedding models as well. AICF performance was also compared against the natural language processing software Linguistic Inquiry Word Count (LIWC). RESULTS: AICF was trained on 80,000 messages obtained from Cancer Chat Canada. We tested AICF on 34,048 messages. Human experts scored 6797 (20%) of the messages to evaluate the ability of AICF to classify group cohesion. Results showed that machine learning algorithms combined with human input could detect group cohesion, a clinically meaningful indicator of effective OSGs. After retraining with human input, AICF reached an F1-score of 0.82. AICF performed slightly better at identifying group cohesion compared to LIWC. CONCLUSIONS: AICF has the potential to assist therapists by detecting discord in the group amenable to real-time intervention. Overall, AICF presents a unique opportunity to strengthen patient-centered care in web-based settings by attending to individual needs. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/21453.

10.
PeerJ ; 12: e17470, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38948230

RESUMO

TIN-X (Target Importance and Novelty eXplorer) is an interactive visualization tool for illuminating associations between diseases and potential drug targets and is publicly available at newdrugtargets.org. TIN-X uses natural language processing to identify disease and protein mentions within PubMed content using previously published tools for named entity recognition (NER) of gene/protein and disease names. Target data is obtained from the Target Central Resource Database (TCRD). Two important metrics, novelty and importance, are computed from this data and when plotted as log(importance) vs. log(novelty), aid the user in visually exploring the novelty of drug targets and their associated importance to diseases. TIN-X Version 3.0 has been significantly improved with an expanded dataset, modernized architecture including a REST API, and an improved user interface (UI). The dataset has been expanded to include not only PubMed publication titles and abstracts, but also full-text articles when available. This results in approximately 9-fold more target/disease associations compared to previous versions of TIN-X. Additionally, the TIN-X database containing this expanded dataset is now hosted in the cloud via Amazon RDS. Recent enhancements to the UI focuses on making it more intuitive for users to find diseases or drug targets of interest while providing a new, sortable table-view mode to accompany the existing plot-view mode. UI improvements also help the user browse the associated PubMed publications to explore and understand the basis of TIN-X's predicted association between a specific disease and a target of interest. While implementing these upgrades, computational resources are balanced between the webserver and the user's web browser to achieve adequate performance while accommodating the expanded dataset. Together, these advances aim to extend the duration that users can benefit from TIN-X while providing both an expanded dataset and new features that researchers can use to better illuminate understudied proteins.


Assuntos
Interface Usuário-Computador , Humanos , Processamento de Linguagem Natural , PubMed , Software
11.
J Cheminform ; 16(1): 76, 2024 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-38956728

RESUMO

Materials science is an interdisciplinary field that studies the properties, structures, and behaviors of different materials. A large amount of scientific literature contains rich knowledge in the field of materials science, but manually analyzing these papers to find material-related data is a daunting task. In information processing, named entity recognition (NER) plays a crucial role as it can automatically extract entities in the field of materials science, which have significant value in tasks such as building knowledge graphs. The typically used sequence labeling methods for traditional named entity recognition in material science (MatNER) tasks often fail to fully utilize the semantic information in the dataset and cannot effectively extract nested entities. Herein, we proposed to convert the sequence labeling task into a machine reading comprehension (MRC) task. MRC method effectively can solve the challenge of extracting multiple overlapping entities by transforming it into the form of answering multiple independent questions. Moreover, the MRC framework allows for a more comprehensive understanding of the contextual information and semantic relationships within materials science literature, by integrating prior knowledge from queries. State-of-the-art (SOTA) performance was achieved on the Matscholar, BC4CHEMD, NLMChem, SOFC, and SOFC-Slot datasets, with F1-scores of 89.64%, 94.30%, 85.89%, 85.95%, and 71.73%, respectively in MRC approach. By effectively utilizing semantic information and extracting nested entities, this approach holds great significance for knowledge extraction and data analysis in the field of materials science, and thus accelerating the development of material science.Scientific contributionWe have developed an innovative NER method that enhances the efficiency and accuracy of automatic entity extraction in the field of materials science by transforming the sequence labeling task into a MRC task, this approach provides robust support for constructing knowledge graphs and other data analysis tasks.

12.
Sci Rep ; 14(1): 16106, 2024 Jul 12.
Artigo em Inglês | MEDLINE | ID: mdl-38997330

RESUMO

The Span-based model can effectively capture the complex entity structure in the text, thus becoming the mainstream model for nested named entity recognition (Nested NER) tasks. However, traditional Span-based models decode each entity span independently. They do not consider the semantic connections between spans or the entities' positional information, which limits their performance. To address these issues, we propose a Bi-Directional Context-Aware Network (Bi-DCAN) for the Nested NER. Specifically, we first design a new span-level semantic relation model. Then, the Bi-DCAN is implemented to capture this semantic relationship. Furthermore, we incorporate Rotary Position Embedding into the bi-affine mechanism to capture the relative positional information between the head and tail tokens, enabling the model to more accurately determine the position of each entity. Experimental results show that compared to the latest model Diffusion-NER, our model reduces 20M parameters and increases the F1 scores by 0.24 and 0.09 on the ACE2005 and GENIA datasets respectively, which proves that our model has an excellent ability to recognise nested entities.

13.
JMIR Form Res ; 8: e54044, 2024 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-38986131

RESUMO

BACKGROUND: Machine learning has advanced medical event prediction, mostly using private data. The public MIMIC-3 (Medical Information Mart for Intensive Care III) data set, which contains detailed data on over 40,000 intensive care unit patients, stands out as it can help develop better models including structured and textual data. OBJECTIVE: This study aimed to build and test a machine learning model using the MIMIC-3 data set to determine the effectiveness of information extracted from electronic medical record text using a named entity recognition, specifically QuickUMLS, for predicting important medical events. Using the prediction of extended-spectrum ß-lactamase (ESBL)-producing bacterial infections as an example, this study shows how open data sources and simple technology can be useful for making clinically meaningful predictions. METHODS: The MIMIC-3 data set, including demographics, vital signs, laboratory results, and textual data, such as discharge summaries, was used. This study specifically targeted patients diagnosed with Klebsiella pneumoniae or Escherichia coli infection. Predictions were based on ESBL-producing bacterial standards and the minimum inhibitory concentration criteria. Both the structured data and extracted patient histories were used as predictors. In total, 2 models, an L1-regularized logistic regression model and a LightGBM model, were evaluated using the receiver operating characteristic area under the curve (ROC-AUC) and the precision-recall curve area under the curve (PR-AUC). RESULTS: Of 46,520 MIMIC-3 patients, 4046 were identified with bacterial cultures, indicating the presence of K pneumoniae or E coli. After excluding patients who lacked discharge summary text, 3614 patients remained. The L1-penalized model, with variables from only the structured data, displayed a ROC-AUC of 0.646 and a PR-AUC of 0.307. The LightGBM model, combining structured and textual data, achieved a ROC-AUC of 0.707 and a PR-AUC of 0.369. Key contributors to the LightGBM model included patient age, duration since hospital admission, and specific medical history such as diabetes. The structured data-based model showed improved performance compared to the reference models. Performance was further improved when textual medical history was included. Compared to other models predicting drug-resistant bacteria, the results of this study ranked in the middle. Some misidentifications, potentially due to the limitations of QuickUMLS, may have affected the accuracy of the model. CONCLUSIONS: This study successfully developed a predictive model for ESBL-producing bacterial infections using the MIMIC-3 data set, yielding results consistent with existing literature. This model stands out for its transparency and reliance on open data and open-named entity recognition technology. The performance of the model was enhanced using textual information. With advancements in natural language processing tools such as BERT and GPT, the extraction of medical data from text holds substantial potential for future model optimization.

14.
BMC Med Inform Decis Mak ; 24(1): 204, 2024 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-39049027

RESUMO

Despite the high creation cost, annotated corpora are indispensable for robust natural language processing systems. In the clinical field, in addition to annotating medical entities, corpus creators must also remove personally identifiable information (PII). This has become increasingly important in the era of large language models where unwanted memorization can occur. This paper presents a corpus annotated to anonymize personally identifiable information in 1,787 anamneses of work-related accidents and diseases in Spanish. Additionally, we applied a previously released model for Named Entity Recognition (NER) trained on referrals from primary care physicians to identify diseases, body parts, and medications in this work-related text. We analyzed the differences between the models and the gold standard curated by a physician in detail. Moreover, we compared the performance of the NER model on the original narratives, in narratives where personal information has been masked, and in texts where the personal data is replaced by another similar surrogate value (pseudonymization). Within this publication, we share the annotation guidelines and the annotated corpus.


Assuntos
Processamento de Linguagem Natural , Humanos , Espanha , Saúde Ocupacional , Narração
15.
Front Plant Sci ; 15: 1368847, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38984153

RESUMO

Introduction: The diversity of edible fungus species and the extent of mycological knowledge pose significant challenges to the research, cultivation, and popularization of edible fungus. To tackle this challenge, there is an urgent need for a rapid and accurate method of acquiring relevant information. The emergence of question and answer (Q&A) systems has the potential to solve this problem. Named entity recognition (NER) provides the basis for building an intelligent Q&A system for edible fungus. In the field of edible fungus, there is a lack of a publicly available Chinese corpus suitable for use in NER, and conventional methods struggle to capture long-distance dependencies in the NER process. Methods: This paper describes the establishment of a Chinese corpus in the field of edible fungus and introduces an NER method for edible fungus information based on XLNet and conditional random fields (CRFs). Our approach combines an iterated dilated convolutional neural network (IDCNN) with a CRF. First, leveraging the XLNet model as the foundation, an IDCNN layer is introduced. This layer addresses the limited capacity to capture features across utterances by extending the receptive field of the convolutional kernel. The output of the IDCNN layer is input to the CRF layer, which mitigates any labeling logic errors, resulting in the globally optimal labels for the NER task relating to edible fungus. Results: Experimental results show that the precision achieved by the proposed model reaches 0.971, with a recall of 0.986 and an F1-score of 0.979. Discussion: The proposed model outperforms existing approaches in terms of these evaluation metrics, effectively recognizing entities related to edible fungus information and offering methodological support for the construction of knowledge graphs.

16.
JMIR Med Inform ; 12: e59680, 2024 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-38954456

RESUMO

BACKGROUND: Named entity recognition (NER) is a fundamental task in natural language processing. However, it is typically preceded by named entity annotation, which poses several challenges, especially in the clinical domain. For instance, determining entity boundaries is one of the most common sources of disagreements between annotators due to questions such as whether modifiers or peripheral words should be annotated. If unresolved, these can induce inconsistency in the produced corpora, yet, on the other hand, strict guidelines or adjudication sessions can further prolong an already slow and convoluted process. OBJECTIVE: The aim of this study is to address these challenges by evaluating 2 novel annotation methodologies, lenient span and point annotation, aiming to mitigate the difficulty of precisely determining entity boundaries. METHODS: We evaluate their effects through an annotation case study on a Japanese medical case report data set. We compare annotation time, annotator agreement, and the quality of the produced labeling and assess the impact on the performance of an NER system trained on the annotated corpus. RESULTS: We saw significant improvements in the labeling process efficiency, with up to a 25% reduction in overall annotation time and even a 10% improvement in annotator agreement compared to the traditional boundary-strict approach. However, even the best-achieved NER model presented some drop in performance compared to the traditional annotation methodology. CONCLUSIONS: Our findings demonstrate a balance between annotation speed and model performance. Although disregarding boundary information affects model performance to some extent, this is counterbalanced by significant reductions in the annotator's workload and notable improvements in the speed of the annotation process. These benefits may prove valuable in various applications, offering an attractive compromise for developers and researchers.

17.
Artigo em Inglês | MEDLINE | ID: mdl-39081233

RESUMO

OBJECTIVES: Active learning (AL) has rarely integrated diversity-based and uncertainty-based strategies into a dynamic sampling framework for clinical named entity recognition (NER). Machine-assisted annotation is becoming popular for creating gold-standard labels. This study investigated the effectiveness of dynamic AL strategies under simulated machine-assisted annotation scenarios for clinical NER. MATERIALS AND METHODS: We proposed 3 new AL strategies: a diversity-based strategy (CLUSTER) based on Sentence-BERT and 2 dynamic strategies (CLC and CNBSE) capable of switching from diversity-based to uncertainty-based strategies. Using BioClinicalBERT as the foundational NER model, we conducted simulation experiments on 3 medication-related clinical NER datasets independently: i2b2 2009, n2c2 2018 (Track 2), and MADE 1.0. We compared the proposed strategies with uncertainty-based (LC and NBSE) and passive-learning (RANDOM) strategies. Performance was primarily measured by the number of edits made by the annotators to achieve a desired target effectiveness evaluated on independent test sets. RESULTS: When aiming for 98% overall target effectiveness, on average, CLUSTER required the fewest edits. When aiming for 99% overall target effectiveness, CNBSE required 20.4% fewer edits than NBSE did. CLUSTER and RANDOM could not achieve such a high target under the pool-based simulation experiment. For high-difficulty entities, CNBSE required 22.5% fewer edits than NBSE to achieve 99% target effectiveness, whereas neither CLUSTER nor RANDOM achieved 93% target effectiveness. DISCUSSION AND CONCLUSION: When the target effectiveness was set high, the proposed dynamic strategy CNBSE exhibited both strong learning capabilities and low annotation costs in machine-assisted annotation. CLUSTER required the fewest edits when the target effectiveness was set low.

18.
Can Assoc Radiol J ; : 8465371241266785, 2024 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-39066637

RESUMO

Purpose: This study evaluates the efficacy of a commercial medical Named Entity Recognition (NER) model combined with a post-processing protocol in identifying incidental pulmonary nodules from CT reports. Methods: We analyzed 9165 anonymized CT reports and classified them into 3 categories: no nodules, nodules present, and nodules >6 mm. For each report, a generic medical NER model annotated entities and their relations, which were then filtered through inclusion/exclusion criteria selected to identify pulmonary nodules. Ground truth was established by manual review. To better understand the relationship between model performance and nodule prevalence, a subset of the data was programmatically balanced to equalize the number of reports in each class category. Results: In the unbalanced subset of the data, the model achieved a sensitivity of 97%, specificity of 99%, and accuracy of 99% in detecting pulmonary nodules mentioned in the reports. For nodules >6 mm, sensitivity was 95%, specificity was 100%, and accuracy was 100%. In the balanced subset of the data, sensitivity was 99%, specificity 96%, and accuracy 97% for nodule detection; for larger nodules, sensitivity was 94%, specificity 99%, and accuracy 98%. Conclusions: The NER model demonstrated high sensitivity and specificity in detecting pulmonary nodules reported in CT scans, including those >6 mm which are potentially clinically significant. The results were consistent across both unbalanced and balanced datasets indicating that the model performance is independent of nodule prevalence. Implementing this technology in hospital systems could automate the identification of at-risk patients, ensuring timely follow-up and potentially reducing missed or late-stage cancer diagnoses.

19.
BMC Med Inform Decis Mak ; 24(1): 192, 2024 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-38982465

RESUMO

BACKGROUND: As global aging intensifies, the prevalence of ocular fundus diseases continues to rise. In China, the tense doctor-patient ratio poses numerous challenges for the early diagnosis and treatment of ocular fundus diseases. To reduce the high risk of missed or misdiagnosed cases, avoid irreversible visual impairment for patients, and ensure good visual prognosis for patients with ocular fundus diseases, it is particularly important to enhance the growth and diagnostic capabilities of junior doctors. This study aims to leverage the value of electronic medical record data to developing a diagnostic intelligent decision support platform. This platform aims to assist junior doctors in diagnosing ocular fundus diseases quickly and accurately, expedite their professional growth, and prevent delays in patient treatment. An empirical evaluation will assess the platform's effectiveness in enhancing doctors' diagnostic efficiency and accuracy. METHODS: In this study, eight Chinese Named Entity Recognition (NER) models were compared, and the SoftLexicon-Glove-Word2vec model, achieving a high F1 score of 93.02%, was selected as the optimal recognition tool. This model was then used to extract key information from electronic medical records (EMRs) and generate feature variables based on diagnostic rule templates. Subsequently, an XGBoost algorithm was employed to construct an intelligent decision support platform for diagnosing ocular fundus diseases. The effectiveness of the platform in improving diagnostic efficiency and accuracy was evaluated through a controlled experiment comparing experienced and junior doctors. RESULTS: The use of the diagnostic intelligent decision support platform resulted in significant improvements in both diagnostic efficiency and accuracy for both experienced and junior doctors (P < 0.05). Notably, the gap in diagnostic speed and precision between junior doctors and experienced doctors narrowed considerably when the platform was used. Although the platform also provided some benefits to experienced doctors, the improvement was less pronounced compared to junior doctors. CONCLUSION: The diagnostic intelligent decision support platform established in this study, based on the XGBoost algorithm and NER, effectively enhances the diagnostic efficiency and accuracy of junior doctors in ocular fundus diseases. This has significant implications for optimizing clinical diagnosis and treatment.


Assuntos
Oftalmologistas , Humanos , Tomada de Decisão Clínica , Registros Eletrônicos de Saúde/normas , Inteligência Artificial , China , Sistemas de Apoio a Decisões Clínicas
20.
Sci Rep ; 14(1): 17488, 2024 07 30.
Artigo em Inglês | MEDLINE | ID: mdl-39080339

RESUMO

Named entity recognition (NER) plays a crucial role in the extraction and utilization of knowledge of ancient Chinese books. However, the challenges of ancient Chinese NER not only originate from linguistic features such as the use of single characters and short sentences but are also exacerbated by the scarcity of training data. These factors together limit the capability of deep learning models, like BERT-CRF, in capturing the semantic representation of ancient Chinese characters. In this paper, we explore the semantic enhancement of NER in ancient Chinese books through the utilization of external knowledge. We propose a novel model based on Graph Neural Networks that integrates two different forms of external knowledge: dictionary-level and chapter-level information. Through the Graph Attention Mechanism (GAT), these external knowledge are effectively incorporated into the model's input context. Our model is evaluated on the C_CLUE dataset, showing an improvement of 3.82% over the baseline BAC-CRF model. It also achieves the best score compared to several state-of-the-art dictionary-augmented models.


Assuntos
Redes Neurais de Computação , Semântica , China , Livros/história , Humanos , Aprendizado Profundo
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