Cassandra and A Room of One's Own: A common cry of frustration.

In this manuscript, we explore the connections between Florence Nightingale's Cassandra and Virginia Woolf's A Room of One's Own while taking the authors' personal and social contexts into account. We conduct a detailed textual analysis from a feminist perspective. Cassandra and A Room of One's Own exhibit singular textual commonalities, such as evidence of trauma, the integration of myth and fiction as literary devices aimed at facilitating the author's access to various social spheres, the use of interpellations to impact the audience, and an argument for education as a path by which privileged women can enter the public realm. Both authors' personal wounds and intellectual frustrations influenced their work, thus making their writing very powerful.

Charcot's contribution to the problem of language in mental medicine.

Jean-Martin Charcot's 1883 lectures on aphasia at the Salpêtrière Hospital were seen as the starting point for the development of a psychology in the work of the famous neurologist. In his lectures, Charcot set out a theory of language function at the cerebral level, distinguishing between the different centers involved in speech production and those necessary for reading. His lectures, which also postulated the independence of ideas from words, were to resonate beyond aphasia specialists, and particularly with alienists. To document this dimension of the reception of neurology in the field of psychiatry, this article refers to Jules Séglas's synthesis on Les troubles du langage chez les aliénés, published in 1892, which summarized the knowledge acquired during the nineteenth century about modifications of expression in madness and whose original ideas were to mark the psychiatric semiology of the early-twentieth century. The analysis details how Séglas cited and adapted Charcot's conceptions to explain the production of incomprehensible speech in idiocy and the formation of hallucinations, thus contributing to the spread of the neurologist's model among his fellow alienists.

Ambient temperature-related sex ratio at birth in historical urban populations: the example of the city of Poznan, 1848-1900.

This study examines whether exposure to ambient temperature in nineteenth-century urban space affected the ratio of boys to girls at birth. Furthermore, we investigate the details of temperature effects timing upon sex ratio at birth. The research included 66,009 individual births, aggregated in subsequent months of births for the years 1847-1900, i.e. 33,922 boys and 32,087 girls. The statistical modelling of the probability of a girl being born is based on logistic GAM with penalized splines and automatically selected complexity. Our research emphasizes the significant effect of temperature in the year of conception: the higher the temperature was, the smaller probability of a girl being born was observed. There were also several significant temperature lags before conception and during pregnancy. Our findings indicate that in the past, ambient temperature, similar to psychological stress, hunger, malnutrition, and social and economic factors, influenced the viability of a foetus. Research on the effects of climate on the sex ratio in historical populations may allow for a better understanding of the relationship between environmental factors and reproduction, especially concerning historical populations since due to some cultural limitations, they were more prone to stronger environmental stressors than currently.

Drivers of autochthonous malaria cases over time: could the Central European present the African future?

BACKGROUND: Results of spatial and temporal comparison of malaria hotspots and coldspots could improve the health measures of malaria control and eradication strategies. The study aimed to reveal the spatially and temporally independent correlations between the potentially most effective background variables and the number of autochthonous malaria cases. METHODS: Relationships between malaria cases and background variables were studied in 2 km × 2 km sized quadrates (10 Central European and 10 African). In addition to the current habitat structure of the African sites, annual precipitation, and annual mean temperature, data of the above parameters detected in the nineteenth and twentieth centuries and currently in the Central European sites were included in the analyses (n = 40). Mann-Whitney tests, Principal Component Analysis, and Generalized Linear Models were used for the examinations. RESULTS: In addition to the apparent significant positive correlation of malaria cases with annual rainfall and mean temperature, several correlations were found for habitat parameters. The cover of marshlands in the 19th-century habitat structure of Central European quadrates was considerably the same as in the recent African ones. The extent of rural residential areas was significantly smaller in the 19th-century habitat structure of Central European quadrats than in present-day African ones. According to the revealed correlations, the surface cover of rural residential areas is the main driver of the number of autochthonous malaria cases that we can directly impact. CONCLUSIONS: The study confirmed with historical comparison that not only the annual rainfall and mean temperature, the cover of marshlands and other habitats with breeding sites, but also the elements of the rural human environment play a significant role in the high number of autochthonous malaria cases, probably through the concentration and enhancing sites for vector mosquitoes. The latter confirms that a rapid urbanization process could reduce malaria cases in the most infected areas of Africa. Until the latter happens, extensive biological control of Anopheles larvae and chemical control (both outdoor and indoor) of their imagoes, further mosquito nets, repellents, and carbon dioxide traps will need to be applied more widely in the most heavily infested areas.

Henry Hun and his family: Three foundational stories in the history of nineteenth-century American neurology, Part I. Thomas Hun (1808-1896): Nineteenth-century patriarch, neurophilosopher, and proto-neurologist.

Thomas Hun (1808-1896)-along with his sons Edward (1842-1880) and Henry (1854-1924)-were prime movers in establishing the clinical practice and academic discipline of neurology in the Hudson River Valley of New York in the ninteenth and early-twentieth centuries. This article outlines the life of the family's semi-aristocratic patriarch, beginning with Thomas's unusual educational background and his six-year post-graduate hiatus in Paris of the 1830s, where he came under the influence of P. C. A. Louis (1787-1872). It lays out his subsequent career as professor of the Institutes of Medicine and ultimately as dean of an American medical school that was not situated in a major metropolis. It also will demonstrate how Thomas Hun's career as a medical practitioner, academician, neurophilosopher, and "proto-neurologist" recapitulates the evolution of clinical and academic neurology in nineteenth-century America.

Crafting British medicine in the Empire: the establishment of medical schools in India and Canada, 1763-1837.

In the early nineteenth century, medical schools became a growing means of regulating medicine in the British Empire, both in the metropole and in two colonies: India and Canada. By examining the establishment of medical schools in Calcutta, Bombay, Madras, Quebec City, Montreal and Toronto between the end of the Seven Years' War and the beginning of the Victorian era, this article argues that the rise of the British Empire was a key factor in the gradual replacement of private medical apprenticeships with institutional medical education. Although the imperial state did not implement a uniform medical policy across the British Empire, the medical schools established under its jurisdiction were instrumental in devising a curriculum that emphasised human dissection, bedside training in hospitals and organic chemistry as criteria of medical competence.

Race, immunity, and lifespan: Unraveling the effect of early-life exposure to malaria risk on lifespan.

We investigate a historical experience to measure the long-term effect of malaria on lifespan among infected survivors and identify a factor that mitigates malaria's effect. Using a sample of Union Army veterans born during the mid-19th century and their lifetime records, we show that exposure to high risk of malaria at birth or in early life substantially shortened their lifespan. The legacy of exposure to malaria is robust while controlling for lifetime socioeconomic and health conditions, fixed effects, and considering selection bias. Additionally, we include the US Colored Troops sample of black veterans to analyze racial differences in the effect of malaria exposure on lifespan. Exposure to malaria did not lead to a shorter lifespan among black veterans. Evidence suggests that genetic immunity to malaria in black veterans might contribute this heterogeneity.

Historical Mortality Dynamics on the Baja California Peninsula : Marriage, Mining Booms, Migration, and Infectious Disease.

Historical demographic research shows that the factors influencing mortality risk are labile across time and space. This is particularly true for datasets that span societal transitions. Here, we seek to understand how marriage, migration, and the local economy influenced mortality dynamics in a rapidly changing environment characterized by high in-migration and male-biased sex ratios. Mortality records were extracted from a compendium of historical vital records for the Baja California peninsula (Mexico). Our sample consists of 1,201 mortality records spanning AD 1835-1900. Findings from Cox proportional hazard models indicate that (1) marriage was associated with a protective effect for both sexes; (2) residing in a mining town was associated with higher mortality for men, but not women; (3) migration was associated with decreased mortality risk for women, but not men; and (4) the risk of mortality increased in the face of infectious disease, but decreased over time. Despite the early initiation of reproduction for women, marriage had a protective effect, likely because marriage linked women to resources. Although mining boomtowns were associated with elevated risk factors generally, only men experienced greater mortality risk, likely due to dangerous working conditions that women did not experience. Last, female, but not male, migrants experienced greater longevity, possibly because exposure to harsh labor conditions eroded the protective effect of selection bias for men. Together, these results shed light on an understudied historical population and broaden our understanding of demographic dynamics in preindustrial settings.

Spanish-French leech trade and its consequences: From the increase in medical demand to resource depletion and technical innovation.

This article studies the impact caused by the success and dissemination of Broussais' theories on the use of leeches as a medical supply on Spanish-French trade relations, as well as its consequences for the Spanish market between 1821 and the 1860s. Analysing the documents produced by the different public administrations, together with newspaper and archival sources in both Spain and France and the literature and legislation of that period, allows us to understand the evolution of this trade and the heavy impact it had on the autochthonous population of this animal resource. The article reveals how, at the beginning of the 1820s, leeches became an important medical supply and how the demand for them increased significantly. This gave rise to a trade relation between Spain and France that led to the overexploitation of the resource, the issuing of regulations on the matter, and the search for technological solutions to increase the production of leeches.

The promises and pitfalls of precision: random and systematic error in physical geodesy, c. 1800-1910.

This article discusses the ways in which nineteenth-century geodesists reflected on precision as an epistemic virtue in their measurement practice. Physical geodesy is often understood as a quintessential nineteenth-century precision science, stimulating advances in instrument making and statistics, and generating incredible quantities of data. Throughout most of the nineteenth century, geodesists indeed pursued their most prestigious research problem - the exact determination of the earth's polar flattening - along those lines. Treating measurement errors as random, they assumed that remaining discordances could be overcome by manufacturing better instruments and extending statistical analysis to a larger amount of data. In the second half of the nineteenth century, however, several German geodesists developed sophisticated methodological critiques of their discipline, in which they diagnosed a too-narrow focus on precision among their peers. On their account, geodesists urgently needed to identify and anticipate the causes of the remaining measurement errors that arose from the earth's little understood interior constitution. While mostly overlooked in the literature, these critiques paved the way for many empirical successes in late nineteenth- and early twentieth-century geodesy, including the first convergent measurements of the earth's polar flattening.

Convenient Frailty: Medical Contestations of Asthma and Hay Fever in African Americans in Late Nineteenth-Century America.

Post-Emancipation medical and social science scholars extensively theorized Black susceptibility to illness, disease, and death. Most studies of late nineteenth-century medical ideas about the relationship between race and disease have highlighted the construction of medical beliefs that associated Black physical weakness with a proclivity to ill health. This study presents an alternate narrative, one where certain diseases - asthma and hay fever - reflected an opposing racialized understanding of disease that instead centered on White frailty. Based on an examination of turn-of-the-century asthma and hay fever medical literature produced by George Miller Beard, the professionalization of the United States Hay Fever Association, and the publication and dismissal of the first recorded case of asthma in an African American man in 1884, this article argues that late nineteenth-century asthma and hay fever physicians, who themselves often suffered from the conditions, defined the typical asthma patient along racial lines to protect the exclusivity of their own professional and social identities. As a result, asthma and hay fever in Black communities, particularly in the North, where asthma and hay fever scholars primarily lived and worked, remained obscured and untreated until the mid-twentieth century.

"They Perished in the Cause of Science": Justus von Liebig's Food for Infants.

In 1867, controversy erupted when Jean-Anne-Henri Depaul, a Paris accoucheur, tested Justus von Liebig's new "food for infants" on four newborns, all of whom died within days. This paper examines the origins of Liebig's food, the debates in the French Academy of Medicine after Depaul's experiment, and how the events were discussed in the medical and popular presses. I argue that the controversy was shaped by a number of interconnected concerns, including the product's impracticality, disagreements within the field of chemistry, the riskiness of Depaul's experimentation, Liebig's problematic celebrity, the potential hubris of trying to emulate a natural product, and national tensions between France and Germany. Infant feeding was an emotionally charged and highly politicized site where multiple interests, anxieties, and ways of knowing collided. Although commercial infant foods, many of which made reference to Liebig in their advertising, would ultimately find popularity in the last decades of the nineteenth century, close attention to the first years of Liebig's product demonstrates that its credibility as a "scientific" mode of infant feeding was far from assured. Rather, Liebig's milk illustrates the early challenges of constructing and enforcing knowledge and trust at the intersection between food, science, and infant life, in both professional and popular arenas.

Carl Bergmann (1814-1865) and the discovery of the anatomical site in the retina where vision is initiated.

A preeminent quest of nineteenth-century visual neuroscience was to identify the anatomical elements of the retina that respond to light. A major breakthrough came in 1854, when Carl Bergmann discovered through direct observation that the human fovea contains only rods and cones. On this basis, he argued that these must necessarily be the light-sensitive elements (i.e., photoreceptors) that initiate vision. Bergmann also argued that Henle's fibers form part of the necessary anatomical link between these distal elements and the proximal ganglion cells, which transmit visual signals to the brain via the optic nerve. However, despite his achievement, Heinrich Müller, not Bergmann, is remembered as the discoverer of human photoreceptors in the literature. This article seeks to correct the record. It situates Bergmann's work alongside that of his contemporaries, sets out his arguments and the critique he received using archival documents, and makes this history more accessible for current readers by comparing what was said to what we know now. We argue that Bergmann's arguments are at least as compelling as those of Müller, and that he should be recognized as a codiscoverer of the anatomic site in the retina where vision is initiated.

Erica L. (Ericaceae): homonyms amongst published names for African species and proposed replacement names.

In support of ongoing taxonomic work on the large and complex flowering plant genus Erica (Ericaceae), we document nineteen pairs of homonyms representing currently used illegitimate names. We provide replacements for thirteen names and new typifications for five. We relegate five names to synonymy: Ericaaemula Guthrie & Bolus under Ericadistorta Bartl.; Ericaarmata Klotzsch ex Benth. under Ericaumbrosa H. A. Baker; Ericacapensis T.M. Salter under Ericaturbiniflora Salisb.; Ericalanata Andrews under Ericaflaccida Link; and Ericatomentosa Salisb. under Ericavelutina Bartl. Finally, we suggest conservation of Ericaaristata Andrews. The new names are: Ericaadelopetala E.C. Nelson & E.G.H. Oliv. replacing Ericainsignis E.G.H. Oliv.; Ericabombycina E.C. Nelson & Pirie replacing Ericaniveniana E.G.H. Oliv.; Ericaconcordia E.C. Nelson & E.G.H. Oliv. replacing Ericaconstantia Nois. ex Benth.; Ericadidymocarpa E.C. Nelson & E.G.H. Oliv. replacing Ericarugata E.G.H. Oliv.; Ericagalantha E.C. Nelson & E.G.H. Oliv. replacing Ericaperlata Benth.; Ericamallotocalyx E.C. Nelson & E.G.H. Oliv. replacing Ericaflocciflora Benth.; Ericanotoporina E.C. Nelson & E.G.H. Oliv. replacing E.autumnalis L.Bolus; Ericaoliveranthus E.C. Nelson & Pirie replacing Ericatenuis Salisb.; Ericaoraria E.C. Nelson & E.G.H. Oliv. replacing Ericaspectabilis Klotzsch ex Benth.; Ericaoresbia E.C. Nelson & E.G.H. Oliv. replacing Ericademissa Klotzsch ex Benth.; Ericapoculiflora E.C. Nelson & E.G.H. Oliv. replacing Ericastenantha Klotzsch ex Benth.; Ericarhodella E.C. Nelson & E.G.H. Oliv. replacing Ericarhodantha Guthrie & Bolus; Ericasupranubia E.C. Nelson & Pirie replacing Ericapraecox Klotzsch.

"Heroic" medicine in neurology: A historical perspective.

BACKGROUND AND PURPOSE: Repetitive bloodletting, promoting profuse diarrhoea and vomiting, the formation of artificial ulcers, and other aggressive treatment methods based on humoral theory and Brunonian medicine were used for patients with nervous system (NS) diseases until the end of the 19th century. These methods are also termed "heroic" medicine by modern medical historians. METHODS: I analysed doctoral dissertations on the subject of NS diseases, clinical reports from 1806 to 1842 from the Vilnius University clinics, and other primary sources. This study was conducted in the vein of a historical-medical analysis and synthesis of primary sources, using comparative analysis, analogy, descriptive methods, and the method of retrospective diagnosis. RESULTS: Copious bloodletting, purgatives, leeches, cupping therapy, and other potentially harmful methods were frequently employed as habitual treatments for patients with NS diseases. Calomel was used as a purgative and an anti-inflammatory drug, and acidum borussicum was prescribed for patients with hydrophobia. After analysing three clinical cases, I revealed how principles of desperate, "heroic" medicine were applied to treat severe NS diseases with the "strongest" drugs, described in the scientific literature of the time. CONCLUSIONS: My work was not intended to judge or criticize historical treatment methods but to demonstrate on what contemporary scientific theories they were based. We should not rule out the idea that some aggressive treatment methods used nowadays, although they eradicate or reduce the burden of a NS disease, or even prolong patients' lives, may offer exceptional examples of 21st century "heroic" medicine for future generations.

Pampean megamammals in Europe: the fossil collections from Santiago Roth.

Santiago Roth was a Swiss fossil finder, naturalist, and paleontologist that emigrated to Argentina in 1866. His work largely influenced the discipline in the country at the end of the twentieth century, particularly the stratigraphy of the Pampean region. Some of his collections of Pampean fossils were sold to museums and private collectors in Europe and were accompanied by elaborated catalogues. Fossils in the Roth's catalogues N° 2 and 3 are housed today in the Natural History Museum of Denmark, fossils from catalogues N° 4 to 6, were sold to Swiss museums, with Catalogue N° 5 currently housed at the Department of Paleontology, Universität Zürich. Here, we provide a general framework on the stratigraphy from the Roth's Pampean fossil sites, summarize the history of the Pampean fossils in Europe originally collected by Roth, and provide historical and curatorial details of the Roth's collection at the Department of Paleontology, Universität Zürich. Supplementary Information: The online version contains supplementary material available at 10.1186/s13358-023-00283-5.

Santiago Roth fue un buscador de fósiles, naturalista y paleontólogo suizo que emigró a la Argentina en 1866. Su obra influyó en gran medida en la disciplina del país a fines del siglo XX, con algunos aportes que son pilares, en particular aquellos para la comprensión de la estratigrafía de la Región Pampeana. Algunas de sus colecciones de fósiles pampeanos fueron vendidas a museos y coleccionistas privados en Europa y estaban acompañadas de catálogos elaborados. Los fósiles de los catálogos N° 2 y 3 de Roth se encuentran hoy en el Museo de Historia Natural de Dinamarca, los fósiles de los catálogos N° 4 a 6 fueron vendidos a museos suizos, mientras que el Catálogo N° 5 en particular está alojado actualmente en el Departamento de Paleontología, Universidad de Zurich. Aquí proporcionamos un marco general sobre la estratigrafía de los sitios de los fósiles pampeanos de Roth, resumimos la historia de los fósiles pampeanos en Europa colectados originalmente por Roth y brindamos detalles históricos y curatoriales de la colección de Roth del Departamento de Paleontología, Universidad de Zurich.

Mining knowledge: Nineteenth-century Cornish electrical science and the controversies of clay.

Michael Faraday's laboratory experiments have dominated traditional histories of the electrical sciences in 1820s and 1830s Britain. However, as this article demonstrates, in the mining region of Cornwall, Robert Were Fox fashioned a very different approach to the study of electromagnetic phenomena. Here, it was the mine that provided the foremost site of scientific experimentation, with Fox employing these underground locations to measure the Earth's heat and make claims over the existence of subterranean electrical currents. Yet securing philosophical claims cultivated in mines proved challenging for Fox, with metropolitan audiences, including Faraday, loath to give credit to the results of these underground experiments. This article explores how Fox developed a way of modeling his mine experiments, using clay samples, to communicate knowledge from industrial Cornwall to urban centers of elite science. It argues that the mine was an epistemologically complex venue of scientific activity, at once seeming to provide a way of examining nature directly, without recourse to laboratory contrivance, while simultaneously being a place where knowledge claims were hard to verify without access to these physically challenging locations. In exploring Fox's work, this study contributes to a growing literature of spatial investigation that takes the vertical as its unit of analysis.

'Pearls' of the nineteenth-century: from therapeutic actors to global commodities medicinal leeches in the Ottoman Empire.

Nineteenth-century physicians increasingly favoured leeching - the placing of a live leech onto a patient's skin to stimulate or limit blood flow - as a cure for numerous ailments. As conviction in their therapeutic properties spread, leech therapy dominated European medicine; France imported over fifty million leeches in one year. Demand soon outpaced supply, spawning a lucrative global trade. Over-collection and farming eventually destroyed leech habitats, wreaked environmental havoc and forced European merchants to seek new supply sources. Vast colonies of leeches were found to inhabit the immense wetlands of the Ottoman Empire, which soon became a major exporter of medicinal leeches. Following the Treaty of Balta Liman (1838), the Ottoman state moved to exert control over the lucrative trade, imposing a tax on leech gathering and contracting with tax-farmers (mültezim) to collect the taxes. British diplomats, merchants and other stakeholders protested the imposition of the tax, as had previously happened with the commodification of wildlife; their pursuit of profit led collectors and farmers to over-gather leeches, with catastrophic consequences. By the end of the century, so great had their worth climbed that the leech population faced extinction. This paper situates medicinal leeches as therapeutic actors of history and adopts an interscale approach in formulating the human-leech interaction. It offers a substantive contribution to the history of medicine, in revealing the centrality of leeches to the rise of modern medicine and global trade, but also by making visible their role in shaping imperial diplomacy and worldwide economic markets.

A Genealogy of the Life History Album (1884): Gerontology, Genre, and Health Across the Life Span.

This paper demonstrates what emerges when we undertake a literary reading of a medical text, examining its form and structure as a text. The study of what appears to be a singular publication reveals instead an under-examined moment in medical history that anticipates contemporary health investigations in modern medicine, while reflecting the limitations of medical and gerontological knowledge in the 1880s. I demonstrate this argument by conducting a Foucauldian archeology of the text, with attention to authorship and the concept of textual genre. My primary text is the Life History Album (1884), which I link to a related endeavor, G. M. Humphry's Old Age (1889), a little-known publication that contains medical observations on the resiliency of aging bodies and anticipates ideas associated with early twentieth-century geriatrics. My investigation brings new attention to the work of Dr. Frederick Akbar Mahomed, a pioneer in the study of hypertension, whose story is part of the genealogy of the text. Inviting its creator to keep records of health throughout the life span, the Life History Album anticipates a new kind of modern subject, who participates in co-creating his or her medical and life health history, whereas Humphry's Old Age, which draws on similar methods, is humanistic, includes literary references, and allows for contentment in older age.

Royle's sympathectomy for spastic paralysis: Sorry saga or scientific awakening?

On October 20, 1924, at the Waldorf-Astoria Hotel in New York City, two medical graduates of the University of Sydney delivered the John B. Murphy Oration to the American College of Surgeons on the topic of sympathetic ramisection for the treatment of spastic paralysis. The surgery was regarded as a triumph. The triumph, however, was short-lived, when one of the speakers, John Irvine Hunter, a promising anatomist, died prematurely. Norman Royle, an orthopedic surgeon, continued the research program and continued to perform these operations. Within a few short years, however, the theory of the dual nerve supply of skeletal muscle, which underpinned the procedure, and the results of surgery for spastic paralysis came under question. Nevertheless, Royle's sympathectomy found another indication and became the treatment of choice for peripheral vascular disease for several decades thereafter. Although Hunter and Royle's original work was discredited, their research turned their sorry saga into a scientific awakening of the sympathetic nervous system.