1.
Psychiatr Neurol Med Psychol (Leipz)
; 32(4): 214-9, 1980 Apr.
Artigo
em Alemão
| MEDLINE
| ID: mdl-6968077
RESUMO
Studies of the permeation of PAMBA in the cerebrospinal fluid of patients with intact or disturbed BBB function after oral administration of 6 g and withdrawal of the spinal fluid after 120 minutes exclusively showed concentrations which were below the identification threshold of the method using 1 micron per millilitre. Patients suffering from subarachnoidal haemorrhages mainly showed a permeation of PAMBA in the cerebrospinal fluid which, however, only rarely reached the lower therapeutically necessary concentration.