RESUMO
Ether or chloroform, was in use for ambulatory surgery after 1861 in Japan. An inhalational anesthetic, especially chloroform, was administered for cesarean section in early Meiji Period (from 1868) up to 1897. According to an article in 1903, chloroform was recommended as a strategy for internal cephalic version. However, it is uncertain whether inhalational anesthetic had been utilized for vaginal deliveries before 1903. There is evidence that hypnosis had attracted attention as a method of labor analgesia around that time.
Assuntos
Analgesia Obstétrica/história , Analgesia Obstétrica/métodos , Hipnose Anestésica/história , Anestésicos Inalatórios/história , Cesárea/história , Cesárea/métodos , Clorofórmio/história , Éteres/história , Feminino , História do Século XIX , História do Século XX , Humanos , Hipnose Anestésica/métodos , Japão , GravidezRESUMO
Williamson serendipitously discovered (1851) a new and efficient way to produce esters using ethyl iodide and potassium salts and in doing so elucidated the molecular mechanism behind ether formation. Lassaigne (1820) made the analogy between sulphovinic and phosphovinic acids and demonstrated the existence of phosphovinic acid, while Pelouze (1833) synthesised monoethyl phosphovinic acid. Finally 1848 Voegeli produced diethyl phosphovinic acid and the first neutral ester of phosphoric acid, the triethyl phosphate (TEP). The successes of Lassaigne and Pelouze in producing phosphovinic acids and Mitscherlich's theory of isomorphism fuelled the search for the vinic acids of arsenic, phosphorus neighbor in the periodic system. This short report attempts to identify the (less known) pharmacists and chemists involved in the quest for both arsenovinic acids and the neutral esters of arsenic and pyroarsenic acids.
Assuntos
Arsenicais/história , Química/história , Éteres/história , Arsenicais/síntese química , Éteres/síntese química , França , História do Século XIX , Indicadores e ReagentesRESUMO
On December 30, 2010, Ross C. Terrell, PhD, died. With his passing at age 85, we lost one of the pioneers of modern anesthesia. Terrell synthesized most of the inhalation anesthetics used today, including desflurane, enflurane, isoflurane, and sevoflurane.
Assuntos
Anestesiologia/história , Anestésicos/história , Anestésicos/síntese química , Éteres/história , História do Século XX , New YorkRESUMO
The use of glycol ethers has changed significantly over the past 30 years. Low molecular weight E-series have been phased-out and progressively replaced by low molecular weight P-series whenever possible. There is a trend to shift from E-series to P-series and an obvious willingness to substitute where alternative solutions exist or as a consequence of strengthening regulation and voluntary measures to reduce exposure in the workplace.
Assuntos
Indústria Química/tendências , Éteres/história , Etilenoglicóis/história , Substâncias Perigosas/história , Propilenoglicóis/história , Solventes/história , Exposição Ambiental/legislação & jurisprudência , Éteres/química , Éteres/toxicidade , Etilenoglicóis/química , Etilenoglicóis/toxicidade , Substâncias Perigosas/toxicidade , História do Século XX , História do Século XXI , Humanos , Peso Molecular , Propilenoglicóis/química , Propilenoglicóis/toxicidade , Solventes/química , Solventes/toxicidadeAssuntos
Lipídeos/história , Animais , Éteres/química , Éteres/história , Éteres/metabolismo , História do Século XX , Humanos , Metabolismo dos Lipídeos , Lipídeos/química , Fator de Ativação de Plaquetas/química , Fator de Ativação de Plaquetas/história , Fator de Ativação de Plaquetas/metabolismo , Pesquisa/históriaRESUMO
Etherizations were developed in USA and was applied for the first time of the dentist Thomas Greene Morton (1819-1868) in 1846. Professor Dr. Ole Secher (1918-1996) studied the first Danish anaesthesias and discovered that the first etherization was carried out in February 1847 at the surgical department, Almindelig Hospital in Copenhagen. The patient was a young girl, with an albus tumore in the knee. She was etherized during an appliqué of ferrum candens. Dr. Secher was not able to find the case record, but she was identified in the hospital records dated 1846 and 1847. The hospital was separated in an alms department and a hospital. Patients were not allowed to stay at the hospital for more than 6 months, then they were placed in the alms department. The etherization was carried out in the alms department, to which the girl was transferred from the hospital. Reviewing the hospital records for the previous 6 months the girl was identified at the surgical department. Her name was Amalie, and she was 14 years old. She died two months after the etherization in April 1847.
Assuntos
Anestesiologia/história , Criança Hospitalizada/história , Éteres/história , Hospitais/história , Criança , Dinamarca , Cuidado Periódico , História do Século XIX , HumanosAssuntos
Anestésicos Inalatórios , Éteres , Éteres Metílicos , Anestesia por Inalação , Anestésicos Inalatórios/administração & dosagem , Anestésicos Inalatórios/química , Anestésicos Inalatórios/economia , Anestésicos Inalatórios/história , Ensaios Clínicos como Assunto , Custos de Medicamentos , Estabilidade de Medicamentos , Éteres/administração & dosagem , Éteres/química , Éteres/economia , Éteres/história , Fluoretos/química , História do Século XX , Humanos , SevofluranoRESUMO
El 11 de diciembre de 1994 se cumplen 150 años del descubrimiento de la anestesia. Cuatro personajes se disputaron en el siglo XIX el honor de este descubrimiento: Charles Jackson (químico), Crawford Long (médico), William Morton (odontólogo) y Horace Wells (odontólogo). Crawford Long en 1800, realizó experimentos con óxido nitroso y planteò la posibilidad de que éste podría eliminar el dolor, incluso en cirugías mayores. Sin embargo, Long no continúo su experimentación. Horace Wells en 1844 ensayó el óxido nitroso como anestésico y continuó experimentando con él. Luego comunicó su descubrimiento en Boston, pero sin éxito; posteriormente en Paris, donde sí lo premiaron con el título de doctor en Medicina. Charles Jackson y William Morton en 1846, ensayaron con el éter, hicieron público xu éxito como anestésico y lo patentaron. Morton fue aceptado universalmente como el descubridor de la anestesia en 1848 hasta 1863. En 1964, la Asociación Dental Americana por resolución, reconoció a Horace Wells como el verdadero descubridor, aunque tarde, porque Wells ya había muerto. En 1870, la Asociación Médica Americana también aceptó a Horace Wells como el descubridor de la anestesia
