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1.
Injury ; 49(7): 1302-1306, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29908851

RESUMO

INTRODUCTION: Percutaneously-placed sacroiliac (SI) screws are currently the gold-standard fixation technique for fixation of the posterior pelvic ring. The relatively high prevalence of sacral dysmorphism in the general population introduces a high risk of cortical breach with resultant neurovascular damage. This study was performed to compare the accuracy of SI screw placement with and without the use of intraoperative navigation, as well as to externally validate the sacral dysmorphism score in a trauma patient cohort. PATIENTS AND METHODS: All trauma patients who underwent sacroiliac screw fixation for pelvic fractures at a level 1 trauma centre over a 6 year period were identified. True axial and coronal sacral reconstructions were obtained from their pre-operative CT scans and assessed qualitatively and quantitatively for sacral dysmorphism - a sacral dysmorphism score was calculated by two independent assessors. Post-operative CT scans were then analysed for breaches and correlated with the hospital medical records to check for any clinical sequelae. RESULTS: 68 screws were inserted in 36 patients, most sustaining injuries from road traffic accidents (50%) or falls from height (36.1%). There was a male preponderance (83.3%) with the majority of the screws inserted percutaneously (86.1%). Intraoperative navigation was used in 47.2% of the patient cohort. 30.6% of the cohort were found to have dysmorphic sacra. The mean sacral dysmorphism scores were not significantly different between navigated and non-navigated groups. Three cortical breaches occurred, two in patients with sacral dysmorphism scores >70 and occurring despite the use of intraoperative navigation. There was no significant difference in the rates of breach between navigated and non-navigated groups. None of the breaches resulted in any clinically observable neurovascular deficit. CONCLUSION: The sacral dysmorphism score can be clinically applied to a cohort of trauma patients with pelvic fractures. In patients with highly dysmorphic sacra, reflected by high sacral dysmorphism scores, intraoperative navigation is not in itself sufficient to prevent cortical breaches. In such patients it would be prudent to consider instrumentation of the lower sacral corridors instead.


Assuntos
Parafusos Ósseos , Fixação Interna de Fraturas/instrumentação , Fraturas Ósseas/cirurgia , Ílio/cirurgia , Sacro/cirurgia , Adulto , Estudos de Avaliação como Assunto , Feminino , Fluoroscopia , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/patologia , Humanos , Ílio/anormalidades , Ílio/anatomia & histologia , Ílio/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Pesquisa Qualitativa , Reprodutibilidade dos Testes , Sacro/anormalidades , Sacro/anatomia & histologia , Sacro/diagnóstico por imagem , Centros de Traumatologia
2.
Skeletal Radiol ; 47(8): 1171-1175, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29445931

RESUMO

Iliac bone malformations are rare and result from early disturbance of the genetic and epigenetic processes that come together to form the pelvic girdle. We report the case of a 5-month-old boy found to have a duplication of the ilium and describe the likely causes of this very rare malformation.


Assuntos
Ílio/anormalidades , Humanos , Ílio/diagnóstico por imagem , Lactente , Masculino , Ossos Pélvicos/diagnóstico por imagem , Radiografia , Sacro/diagnóstico por imagem
3.
JBJS Case Connect ; 7(3): e62, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29252891

RESUMO

CASE: The S1 and S2 corridors are the typical osseous pathways for iliosacral screw fixation of posterior pelvic ring fractures. In dysmorphic sacra, the S1 screw trajectory is often different from that in normal sacra. We present a case of iliosacral screw placement in the third sacral segment for fixation of a complex lateral compression type-3 pelvic fracture in a patient with a dysmorphic sacrum. CONCLUSION: In patients with dysmorphic sacra and unstable posterior pelvic ring fractures or dislocations, the S3 corridor may be a feasible osseous fixation pathway that can be used in a manner equivalent to the S2 corridor in a normal sacrum.


Assuntos
Pontos de Referência Anatômicos/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Ílio/cirurgia , Ossos Pélvicos/cirurgia , Sacro/cirurgia , Adulto , Parafusos Ósseos/normas , Feminino , Fraturas Ósseas/classificação , Fraturas por Compressão/complicações , Fraturas por Compressão/cirurgia , Humanos , Ílio/anormalidades , Ílio/diagnóstico por imagem , Procedimentos Ortopédicos/instrumentação , Ossos Pélvicos/anormalidades , Ossos Pélvicos/diagnóstico por imagem , Sacro/anormalidades , Sacro/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento
4.
Clin Orthop Relat Res ; 474(10): 2304-11, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27392768

RESUMO

BACKGROUND: Percutaneous iliosacral screw placement is the standard procedure for fixation of posterior pelvic ring lesions, although a transsacral screw path is being used more frequently in recent years owing to increased fracture-fixation strength and better ability to fix central and bilateral sacral fractures. However, biomorphometric data for the osseous corridors are limited. Because placement of these screws in a safe and effective manner is crucial to using transsacral screws, we sought to address precise sacral anatomy in more detail to look for anatomic variation in the general population. QUESTIONS/PURPOSES: We asked: (1) What proportion of healthy pelvis specimens have no transsacral corridor at the level of the S1 vertebra owing to sacral dysmorphism? (2) If there is no safe diameter for screw placement in the transsacral S1 corridor, is an increased and thus safe diameter of the transsacral S2 corridor expected? (3) Are there sex-specific differences in sacral anatomy and are these correlated with known anthropometric parameters? METHODS: CT scans of pelves of 280 healthy patients acquired exclusively for medical indications such as polytrauma (20%), CT angiography (70%), and other reasons (10%), were segmented manually. Using an advanced CT-based image analysis system, the mean shape of all segmented pelves was generated and functioned as a template. On this template, the cylindric transsacral osseous corridor at the level of the S1 and S2 vertebrae was determined manually. Each pelvis then was registered to the template using a free-form registration algorithm to measure the maximum screw corridor diameters on each specimen semiautomatically. RESULTS: Thirty of 280 pelves (11%) had no transsacral S1 corridor owing to sacral dysmorphism. The average of maximum cylindrical diameters of the S1 corridor for the remaining 250 pelves was 12.8 mm (95% CI, 12.1-13.5 mm). A transverse corridor for S2 was found in 279 of 280 pelves, with an average of maximum cylindrical diameter of 11.6 mm (95% CI, 11.3-11.9 mm). Decreasing transsacral S1 corridor diameters are correlated with increasing transsacral S2 corridor diameters (R value for females, -0.260, p < 0.01; for males, -0.311, p < 0.001). Female specimens were more likely to have sacral dysmorphism (defined as a pelvis without a transsacral osseous corridor at the level of the S1 vertebra) than were male specimens (females, 16%; males, 7%; p < 0.003). Furthermore female pelves had smaller-corridor diameters than did male pelves (females versus males for S1: 11.7 mm [95% CI, 10.6-12.8 mm] versus 13.5 mm [95% CI, 12.6-14.4 mm], p < 0.01; and for S2: 10.6 mm [95% CI, 10.1-11.1 mm] versus 12.2 mm [95% CI, 11.8-12.6 mm ], p < 0.0001). CONCLUSIONS: Narrow corridors and highly individual, sex-dependent variance of morphologic features of the sacrum make transsacral implant placement technically demanding. Individual preoperative axial-slice CT scan analyses and orthogonal coronal and sagittal reformations are recommended to determine the prevalence of sufficient-sized osseous corridors on both levels for safe screw placements, especially in female patients, owing to their smaller corridor diameters and higher rate of sacral dysmorphism.


Assuntos
Parafusos Ósseos , Procedimentos Ortopédicos/instrumentação , Ossos Pélvicos/diagnóstico por imagem , Ossos Pélvicos/cirurgia , Tomografia Computadorizada por Raios X , Adulto , Idoso , Idoso de 80 Anos ou mais , Pontos de Referência Anatômicos , Feminino , Voluntários Saudáveis , Humanos , Ílio/anormalidades , Ílio/diagnóstico por imagem , Ílio/cirurgia , Masculino , Pessoa de Meia-Idade , Procedimentos Ortopédicos/efeitos adversos , Ossos Pélvicos/anormalidades , Valor Preditivo dos Testes , Interpretação de Imagem Radiográfica Assistida por Computador , Sacro/anormalidades , Sacro/diagnóstico por imagem , Sacro/cirurgia , Caracteres Sexuais , Fatores Sexuais , Adulto Jovem
6.
Eur J Hum Genet ; 24(1): 44-50, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25898926

RESUMO

Nail-Patella Syndrome (NPS) is a rare autosomal dominant condition comprising nail and skeletal anomalies. Skeletal features include dysplastic patellae and iliac horns, as well as scapula and elbow dysplasia. Nephropathy and glaucoma or intra-ocular hypertension can sometimes be present. NPS is due to variants affecting function in LMX1B, which encodes a LIM-homeodomain protein critical for limb, kidney and eye development. We describe the phenotype and the molecular data of 55 index patients and their 39 relatives presenting with typical NPS. We identified 38 different LMX1B anomalies, 19 of which were not reported before. In our series, 9% of families are not carriers of a LMX1B genomic alteration after extensive study of the coding and non-coding regions of the gene. One of the families showed no linkage to the LMX1B locus, raising the hypothesis of a genetic heterogeneity.


Assuntos
Heterogeneidade Genética , Glaucoma/genética , Proteínas com Homeodomínio LIM/genética , Síndrome da Unha-Patela/genética , Nefrite Hereditária/genética , Hipertensão Ocular/genética , Fatores de Transcrição/genética , Adolescente , Adulto , Criança , Pré-Escolar , Éxons , Feminino , Expressão Gênica , Genes Dominantes , Glaucoma/patologia , Humanos , Ílio/anormalidades , Ílio/metabolismo , Íntrons , Masculino , Pessoa de Meia-Idade , Síndrome da Unha-Patela/patologia , Unhas/metabolismo , Unhas/patologia , Nefrite Hereditária/patologia , Hipertensão Ocular/patologia , Patela/anormalidades , Patela/metabolismo , Fenótipo , Polimorfismo Genético , Escápula/anormalidades , Escápula/metabolismo , Análise de Sequência de DNA
7.
J Spinal Disord Tech ; 27(8): 415-22, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25409119

RESUMO

STUDY DESIGN: A retrospective analysis. OBJECTIVE: To present the surgical outcome of percutaneous endoscopic discectomy (PED) for recurrent herniated intervertebral disk disease (HIVD) and to suggest a surgical strategy. SUMMARY OF BACKGROUND DATA: Revision discectomy is technically demanding because of the scar tissue, unclear anatomic planes, and retraumatization to the posterior structures. Although open microdiscectomy is a standard method, endoscopic techniques have emerged as a surgical alternative with comparable results. PED was performed with either the transforaminal (PETD) or the interlaminar approach (PEID). Previous reports have shown the surgical outcomes of PETD or PEID for recurrent HIVD, but the application of each approach was not addressed clearly. METHODS: Consecutive 26 patients (M:F=16:10, mean age 53.1±12.4 y), who underwent PED for recurrent HIVD, were enrolled. The previous operation was an open discectomy in 22, a PETD in 2, and a PEID in 2 patients. PETD was considered preferentially, if it was feasible (n=11), because of the scar tissue formed by the previous operation. PEID was chosen (n=15) because of a high iliac crest (8), high canal compromise (3), high-grade inferior migration (2), and narrow neural foramen (2). All patients were followed up for 19.3±11.3 months. RESULTS: In all patients, the recurrent disk material was removed successfully, and conversion to an open surgery was not necessary. Postoperative magnetic resonance imaging revealed that the ruptured disk was removed successfully in all cases. A favorable outcome (excellent or good outcome by MacNab's criteria) was achieved in 21 patients (81%). Re-recurrence occurred in 2 patients at 6 and 12 months postoperatively. Risk factors for an unfavorable outcome were not found in the present study (P>0.05). CONCLUSIONS: The relevant utilization of updated surgical techniques may be helpful in overcoming the difficulty of revision surgery.


Assuntos
Discotomia Percutânea/métodos , Endoscopia/métodos , Deslocamento do Disco Intervertebral/cirurgia , Idoso , Feminino , Humanos , Ílio/anormalidades , Região Lombossacral/cirurgia , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos , Recidiva , Resultado do Tratamento
10.
Am J Emerg Med ; 31(10): 1537.e1-2, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23809087

RESUMO

Pelvic digit is a rare congenital anomaly where bone develops in the soft tissue adjacent to normal skeletal bone. Pelvic digits are most often associated with the ilium but may also pseudoarticulate with other pelvic bones or the abdominal wall. Its importance lies in its differentiation from acquired abnormalities due to trauma such as myositis ossificans and avulsion injuries of pelvis. In this article, we present a case of pelvic digit with multiple fractures. To avoid unnecessary investigation methods and treatment, this entity should be kept inmindwhen an atypical bone structure is noted around the pelvis.


Assuntos
Ílio/anormalidades , Adulto , Diagnóstico Diferencial , Fraturas Ósseas/diagnóstico , Humanos , Ílio/diagnóstico por imagem , Ílio/lesões , Vértebras Lombares/anormalidades , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/lesões , Masculino , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/diagnóstico por imagem , Tomografia Computadorizada por Raios X
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