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1.
Photodiagnosis Photodyn Ther ; 39: 102986, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35760351

RESUMO

We report the case of a 20-year-old man with acne conglobata (AC) who was treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) sequentially to deroofing, and finally used fractional carbon dioxide laser for esthetic requirements, achieving satisfying results. AC is a severe form of acne vulgaris that can lead to significant scarring and has serious negative effects on a patient's psychological well-being and quality of life. Some cases are likely resistant to currently available treatments. This report describes a promising, and effective method for the treatment of AC.


Assuntos
Acne Conglobata , Acne Vulgar , Fotoquimioterapia , Acne Conglobata/tratamento farmacológico , Acne Vulgar/tratamento farmacológico , Adulto , Ácido Aminolevulínico/uso terapêutico , Humanos , Masculino , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/uso terapêutico , Qualidade de Vida , Resultado do Tratamento , Adulto Jovem
7.
Cutis ; 100(6): E23-E26, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29360905

RESUMO

Acne fulminans is an uncommon and debilitating disease that presents as an acute eruption of nodular and ulcerative acne lesions in association with systemic symptoms. It occurs commonly during treatment of severe acne (eg, acne conglobata) with isotretinoin in young adolescent male patients. Isotretinoin and doxycycline also can potentially induce development of neutrophilic dermatoses in patients with severe acne lesions, which are characterized by the acute appearance of painful ulcerative papulonodules accompanied by systemic symptoms including fever and leukocytosis. We report a challenging case of a 13-year-old adolescent boy who acutely developed hundreds of ulcerative plaques as well as systemic symptoms after being treated with doxycycline and isotretinoin for acne conglobata. He was treated with prednisone, dapsone, and colchicine and had to switch to cyclosporine to achieve relief from his condition.


Assuntos
Acne Conglobata/tratamento farmacológico , Doxiciclina/efeitos adversos , Isotretinoína/efeitos adversos , Úlcera Cutânea/induzido quimicamente , Adolescente , Colchicina/administração & dosagem , Ciclosporina/administração & dosagem , Dapsona/administração & dosagem , Fármacos Dermatológicos/administração & dosagem , Fármacos Dermatológicos/efeitos adversos , Doxiciclina/administração & dosagem , Humanos , Isotretinoína/administração & dosagem , Masculino , Neutrófilos/metabolismo , Prednisona/administração & dosagem , Úlcera Cutânea/patologia
9.
Clin Exp Dermatol ; 40(4): 383-6, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25545016

RESUMO

Acne conglobata (AC) is a chronic, severe, inflammatory variant of acne characterized by development of cystic nodules, abscesses and sinus tracts. AC may prove resistant to conventional acne therapy. The off-label use of adalimumab for the treatment of AC has been reported recently. We present a 26-year-old man with AC resistant to conventional treatment, who was treated with 40 mg adalimumab every other week, with significant clinical improvement. We review the evidence for the use of tumour necrosis factor antagonists in AC and related conditions. This case provides further evidence supporting the role of adalimumab in the treatment of AC.


Assuntos
Acne Conglobata/tratamento farmacológico , Adalimumab/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Fator de Necrose Tumoral alfa/antagonistas & inibidores , Adulto , Humanos , Masculino
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