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1.
World Neurosurg ; 149: 169-170, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33647493

RESUMO

A 27-year-old man developed sudden neck pain, severe quadriparesis, and right shoulder allodynia during an outpatient cervical medial branch block procedure. Cervical spine imaging revealed evidence of an interlaminar needle trajectory with abnormal signal in the right hemicord at the level of C4, consistent with intramedullary injection and contusion. Following a 48-hour stay in the intensive care unit, during which hemodynamic vasopressor support was administered to optimize spinal cord perfusion, the patient exhibited almost complete neurologic recovery with resolution of the neuropathic pain. He was eventually discharged home and underwent outpatient physical therapy for a mild residual right hemiparesis.


Assuntos
Bloqueio Nervoso Autônomo/efeitos adversos , Vértebras Cervicais/diagnóstico por imagem , Nervo Mediano/diagnóstico por imagem , Agulhas/efeitos adversos , Quadriplegia/diagnóstico por imagem , Quadriplegia/etiologia , Adulto , Bloqueio Nervoso Autônomo/instrumentação , Humanos , Masculino , Quadriplegia/terapia
2.
Reg Anesth Pain Med ; 44(1): 86-90, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30640658

RESUMO

BACKGROUND AND OBJECTIVES: The exact mechanism of peripheral nerve blocks causing/leading to nerve injury remains controversial. Evidence from animal experiments suggests that intrafascicular injection resulting in high injection pressure has the potential to rupture nerve fascicles and may consequently cause permanent nerve injury and neurological deficits. The B-Smart (BS) in-line manometer and the CompuFlo (CF) computerized injection pump technology are two modalities used for monitoring pressure during regional anesthesia. This study sought to explore the accuracy of these two technologies in measuring needle-tip pressures in a simulated environment. METHODS: In seven simulated needle-syringe combinations, the BS and the CF devices were connected in series through a closed system and attached to a digital manometer at the tip of various needles. The pressures were evaluated in three trials per needle-syringe combination. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy (F1 Score) were determined for each needle type and overall. RESULTS: For pressures ≥15 psi and ≥20 psi, respectively, the CF device demonstrated a sensitivity of 100%, 100%; specificity of 96%, 98%; positive predictive value 93%, 93%; and negative predictive value of 100%, 100%. The BS device demonstrated a sensitivity of 60%, 100%; specificity of 99%, 95%; positive predictive value of 96%, 85%; and negative predictive value of 85%, 100%. Accuracy, as measured by the F1 Score, for detecting a pressure of ≥15 psi was 0.96 for the CF and 0.74 for the BS. CONCLUSIONS: Future research is needed to explore in-vivo performance and evaluate whether either of these devices can impact on clinical outcomes.


Assuntos
Bloqueio Nervoso Autônomo/normas , Bombas de Infusão/normas , Manometria/normas , Agulhas/normas , Anestesia por Condução/instrumentação , Anestesia por Condução/normas , Bloqueio Nervoso Autônomo/instrumentação , Pressão
3.
Anesth Analg ; 124(3): 959-965, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-28151818

RESUMO

BACKGROUND: Continuous peripheral nerve blocks offer advantages over single-injection blocks, including extended analgesia and reduction in opioid consumption. These benefits require that the perineural catheter remain intact for the duration of the planned local anesthetic infusion. Mechanical displacement of catheters, leaking, and consequent failure are known complications. The aim of this study was to evaluate continuous perineural catheter tip-to-nerve apposition in vivo over 48 hours comparing 2 different simple fixation strategies. METHODS: Subjects presenting for a continuous interscalene nerve block were randomized to perineural catheter fixation with 1 of 2 types of adhesive: Dermabond (2-octylcyanoacrylate) or Mastisol (alcohol 23A, gum mastic, storax, and methyl salicylate), covered with a simple transparent dressing. The primary outcome was the evaluation of catheter-to-nerve apposition maintenance over 48 hours via both a blinded ultrasound evaluation of local anesthetic distribution and a blinded clinical assessment. Secondary outcomes included leakage at the catheter site, pain scores, opioid consumption, catheter-to-skin migration at the insertion site, and patient satisfaction. RESULTS: Sixty-six subjects were recruited and randomized to compare adhesive group catheter tip-to-nerve apposition on postoperative day 2 (POD 2). Within the intention-to-treat cohort, a statistically significant decrease of perineural catheter tip-to-nerve apposition in the Mastisol group (64.7%) compared with the Dermabond group (90.6%) on POD 2 (odds ratios [OR] 0.19; 95% confidence interval [CI] 0.05-0.75; P = .012) was observed. Similar results were observed on POD 1 (OR 0.19; 95% CI 0.03-1.38; P = NS) and POD 2 (OR 0.14; 95% CI 0.02-0.97; P = .008) within the as-treated cohort. Catheter leakage (OR 67; 95% CI 7.3-589) and median catheter migration difference at the skin insertion site (2.0 cm; 95% CI 0.5-2.5) were also significantly greater in the Mastisol group than in the Dermabond group from POD 0 to POD 2 (P < .001). Median postoperative opioid consumption difference in morphine equivalents (3.2 mg; 95% CI - 9.0 to 14.2) was not significantly different between the Dermabond and the Mastisol groups through POD 2 (P = .542). CONCLUSIONS: Perineural catheter fixation with Dermabond in continuous interscalene nerve block improves maintenance of catheter-to-nerve apposition when compared with Mastisol.


Assuntos
Bloqueio Nervoso Autônomo/instrumentação , Bloqueio Nervoso Autônomo/métodos , Cateteres de Demora , Cianoacrilatos/administração & dosagem , Resina Mástique/administração & dosagem , Adesivos Teciduais/administração & dosagem , Idoso , Idoso de 80 Anos ou mais , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento
4.
J Orthop Surg Res ; 12(1): 4, 2017 Jan 13.
Artigo em Inglês | MEDLINE | ID: mdl-28086940

RESUMO

BACKGROUND: Peripheral nerve stimulation has been used for decades to treat chronic pain but has not been used for postoperative analgesia due to multiple limitations, beginning with invasive electrode placement. With the development of small-diameter/gauge leads enabling percutaneous insertion, ultrasound guidance for accurate introduction, and stimulators small enough to be adhered to the skin, neurostimulation may now be provided in a similar manner to continuous peripheral nerve blocks. Here, we report on the use of ultrasound-guided percutaneous peripheral nerve stimulation to treat postoperative pain. MATERIALS AND METHODS: Subjects within 60 days of a total knee arthroplasty with pain insufficiently treated with oral analgesics had a 0.2-mm-diameter electrical lead (pre-loaded into a 20 gauge needle) introduced percutaneously using ultrasound guidance with the tip located approximately 0.5-1.0 cm from the femoral nerve (a second lead was inserted approximately 1.0-3.0 cm from the sciatic nerve for posterior knee pain). An external stimulator delivered current. Endpoints were assessed before and after lead insertion and the leads subsequently removed. Due to the small sample size for this pilot/feasibility study, no statistics were applied to the data. RESULTS: Leads were inserted in subjects (n = 5) 8-58 days postoperatively. Percutaneous peripheral nerve stimulation decreased pain an average of 93% at rest (from a mean of 5.0 to 0.2 on a 0-10 numeric rating scale), with 4 of 5 subjects experiencing complete resolution of pain. During passive and active knee motion pain decreased an average of 27 and 30%, respectively. Neither maximum passive nor active knee range-of-motion was consistently affected. CONCLUSIONS: Ultrasound-guided percutaneous peripheral nerve stimulation may be a practical modality for the treatment of postoperative pain following orthopedic surgical procedures, and further investigation appears warranted.


Assuntos
Analgesia/métodos , Artroplastia do Joelho/efeitos adversos , Bloqueio Nervoso Autônomo/métodos , Dor Pós-Operatória/diagnóstico por imagem , Dor Pós-Operatória/terapia , Ultrassonografia de Intervenção/métodos , Idoso , Analgesia/instrumentação , Bloqueio Nervoso Autônomo/instrumentação , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/etiologia , Estudos Prospectivos , Ultrassonografia de Intervenção/instrumentação
5.
Minerva Chir ; 72(2): 125-139, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27981827

RESUMO

Obesity has been on the rise globally and more people are now clinically obese than ever before in the US. This issue has a significant impact on both health and cost to healthcare systems. Bariatric surgery is efficacious in treatment of obesity but only in late stages of the disease, and there is a requirement for less invasive techniques/devices to treat obesity at earlier stages. Currently a number of these are either in clinical trials or have recently been approved by the Food and Drug Administration for weight loss. This review aims to give an overview of the newer technologies and techniques being used in bariatric surgery. It will also give a glimpse into future methods and those that have fallen short in recent times.


Assuntos
Cirurgia Bariátrica/métodos , Invenções , Animais , Bloqueio Nervoso Autônomo/instrumentação , Cirurgia Bariátrica/efeitos adversos , Cirurgia Bariátrica/instrumentação , Cirurgia Bariátrica/tendências , Ensaios Clínicos como Assunto , Estimulação Encefálica Profunda , Eletrodos Implantados , Embolização Terapêutica/métodos , Desenho de Equipamento , Balão Gástrico/efeitos adversos , Esvaziamento Gástrico , Gastrostomia/instrumentação , Humanos , Magnetismo , Metanálise como Assunto , Estudos Multicêntricos como Assunto , Obesidade/epidemiologia , Próteses e Implantes , Estômago/irrigação sanguínea , Estômago/cirurgia , Suínos , Terapias em Estudo , Nervo Vago/fisiologia
6.
Obes Surg ; 27(1): 169-176, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27506803

RESUMO

BACKGROUND: The ReCharge Trial demonstrated that a vagal blocking device (vBloc) is a safe and effective treatment for moderate to severe obesity. This report summarizes 24-month outcomes. METHODS: Participants with body mass index (BMI) 40 to 45 kg/m2, or 35 to 40 kg/m2 with at least one comorbid condition were randomized to either vBloc therapy or sham intervention for 12 months. After 12 months, participants randomized to vBloc continued open-label vBloc therapy and are the focus of this report. Weight loss, adverse events, comorbid risk factors, and quality of life (QOL) will be assessed for 5 years. RESULTS: At 24 months, 123 (76 %) vBloc participants remained in the trial. Participants who presented at 24 months (n = 103) had a mean excess weight loss (EWL) of 21 % (8 % total weight loss [TWL]); 58 % of participants had ≥5 % TWL and 34 % had ≥10 % TWL. Among the subset of participants with abnormal preoperative values, significant improvements were observed in mean LDL (-16 mg/dL) and HDL cholesterol (+4 mg/dL), triglycerides (-46 mg/dL), HbA1c (-0.3 %), and systolic (-11 mmHg) and diastolic blood pressures (-10 mmHg). QOL measures were significantly improved. Heartburn/dyspepsia and implant site pain were the most frequently reported adverse events. The primary related serious adverse event rate was 4.3 %. CONCLUSIONS: vBloc therapy continues to result in medically meaningful weight loss with a favorable safety profile through 2 years. TRIAL REGISTRATION: https://clinicaltrials.gov/ct2/show/NCT01327976.


Assuntos
Bloqueio Nervoso Autônomo/instrumentação , Terapia por Estimulação Elétrica , Eletrodos Implantados , Obesidade Mórbida/terapia , Estimulação do Nervo Vago/métodos , Nervo Vago/cirurgia , Adulto , Bloqueio Nervoso Autônomo/efeitos adversos , Estudos Cross-Over , Método Duplo-Cego , Terapia por Estimulação Elétrica/efeitos adversos , Terapia por Estimulação Elétrica/instrumentação , Terapia por Estimulação Elétrica/métodos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/metabolismo , Qualidade de Vida , Fatores de Risco , Resultado do Tratamento , Nervo Vago/patologia , Estimulação do Nervo Vago/efeitos adversos , Estimulação do Nervo Vago/instrumentação , Redução de Peso/fisiologia
7.
Eur J Anaesthesiol ; 34(3): 135-140, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-28009637

RESUMO

BACKGROUND: Ultrasound-guided nerve blocks have become the standard when performing regional nerve blocks in anaesthesia. Infiniti Plus (CIVCO Medical Solutions, Kalona, Iowa, USA) is a needle guide that has been recently developed to help clinicians in performing ultrasound-guided nerve blocks. OBJECTIVES: We tested the hypothesis that femoral nerve catheter placement carried out with the Infiniti Plus needle guide will be quicker to perform than without the Infiniti Plus. Secondary aims were to assess whether the Infiniti Plus needle guide decreased the number of block attempts and also whether it improved needle visibility. DESIGN: A randomised, controlled trial. SETTING: Cleveland Clinic, Cleveland, Ohio, USA. PATIENTS: We enrolled adult patients having elective total knee arthroplasty with a femoral nerve block and femoral nerve catheter. Patients, who were pregnant or those who had preexisting neuropathy involving the surgical limb, coagulopathy, infection at the block site or allergy to local anaesthetics were excluded. INTERVENTIONS: Patients were randomised into two groups to receive the ultrasound-guided femoral nerve catheter placement with or without the Infiniti Plus needle guide. MAIN OUTCOME MEASURES: The time taken to place the femoral nerve catheter, the number of attempts, the success rate and needle visibility were recorded. We used an overall α of 0.05 for both the primary and secondary analyses; the secondary analyses were Bonferroni corrected to control for multiple comparisons. RESULT: The median (interquartile range Q1 to Q3) time to perform the femoral nerve catheter placement was 118 (100 to 150) s with Infiniti Plus and 177 (130 to 236) s without Infiniti Plus. Infiniti Plus significantly reduced the time spent performing femoral nerve catheterisation, with estimated ratio of means [(95% confidence interval), P value] of 0.67 [(0.60 to 0.75), P < 0.001] with Infiniti Plus compared with no Infiniti Plus. However, Infiniti Plus had no effect on the odds of a successful femoral nerve catheter placement, number of attempts or percentage of perfect needle visibility. CONCLUSION: We found that the use of Infiniti Plus decreased the median time to successfully place a femoral nerve catheter by 33% compared with not using Infiniti Plus. This difference may be more apparent to clinicians undertaking this procedure less often or by those in training as our team was very experienced, had been trained in the technique and was working in a hospital with a large caseload. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT02080481.


Assuntos
Bloqueio Nervoso Autônomo/métodos , Cateterismo/métodos , Nervo Femoral/diagnóstico por imagem , Agulhas , Ultrassonografia de Intervenção/métodos , Idoso , Artroplastia do Joelho/instrumentação , Artroplastia do Joelho/métodos , Bloqueio Nervoso Autônomo/instrumentação , Cateterismo/instrumentação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Ultrassonografia de Intervenção/instrumentação
9.
Reg Anesth Pain Med ; 41(1): 50-5, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26650431

RESUMO

BACKGROUND AND OBJECTIVES: High opening injection pressures (OIPs) have been shown to predict sustained needle tip contact with the roots of the brachial plexus. Such roots have a uniquely high ratio of fascicular versus connective tissue. It is unknown if this relationship is preserved during multifascicular nerve blockade. We hypothesized that OIP can predict needle-nerve contact during femoral nerve block, as well as detect needle contact with the fascia iliaca. METHODS: Twenty adults scheduled for femoral block were recruited. Using ultrasound, a 22-gauge needle was sequentially placed in 4 locations: indenting the fascia iliaca, advanced through the fascia iliaca while lateral to the nerve, slightly indenting the femoral nerve, and withdrawn from the nerve 1 mm. At each location, the OIP required to initiate an injection of 1 mL D5W (5% dextrose in water) at 10 mL/min was recorded. Blinded investigators performed evaluations and aborted injections when an OIP of 15 psi was reached. RESULTS: Opening injection pressure was 15 psi or greater for 90% and 100% of cases when the needle indented the femoral nerve and fascia iliaca, respectively. Opening injection pressure was less than 15 psi for all 20 patients when the needle was withdrawn 1 mm from the nerve as well as at the subfascial position (McNemar χ2 P < 0.001). CONCLUSIONS: Opening injection pressure greater than 15 psi was associated with a block needle tip position slightly indenting the epineurium of the femoral nerve (90%) and the fascia iliaca (100%). Needle tip positions not indenting these structures were associated with OIP of less than 15 psi (100%).


Assuntos
Bloqueio Nervoso Autônomo/métodos , Fáscia/diagnóstico por imagem , Nervo Femoral/diagnóstico por imagem , Injeções , Agulhas , Pressão , Adulto , Idoso , Bloqueio Nervoso Autônomo/instrumentação , Procedimentos Cirúrgicos Eletivos/instrumentação , Procedimentos Cirúrgicos Eletivos/métodos , Feminino , Humanos , Injeções/efeitos adversos , Masculino , Manometria/métodos , Pessoa de Meia-Idade , Pressão/efeitos adversos , Ultrassonografia de Intervenção/instrumentação , Ultrassonografia de Intervenção/métodos
10.
Reg Anesth Pain Med ; 40(5): 610-5, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26222348

RESUMO

For patients with pain from upper abdominal malignancies, celiac plexus neurolysis can provide an effective means of pain control. However, there are instances when traditionally described percutaneous approaches may not be technically feasible. We describe here the successful use of a novel single-needle retroaortic approach as an alternative approach to celiac plexus neurolysis.We present 4 cases of patients with pain from upper abdominal malignancies in whom we performed celiac plexus neurolysis using a novel single-needle retroaortic approach. All 4 patients had significant pain relief and no significant adverse effects from the retroaortic approach.


Assuntos
Dor Abdominal/diagnóstico , Dor Abdominal/terapia , Bloqueio Nervoso Autônomo/instrumentação , Plexo Celíaco , Agulhas , Idoso , Idoso de 80 Anos ou mais , Bloqueio Nervoso Autônomo/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Manejo da Dor/instrumentação , Manejo da Dor/métodos
11.
Ann Agric Environ Med ; 22(2): 353-6, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26094538

RESUMO

INTRODUCTION: Chronic pelvic pain syndrome occurs in 4-14% of women. Pain pathomechanism in this syndrome is complex, as it is common to observe the features of nociceptive, inflammatory, neuropathic and psychogenic pain. The common findings in women with pelvic pain are endometriosis and pelvic adhesions. OBJECTIVE: Aim of the study was to test the effectiveness of pharmacological treatment and regional anesthesia techniques for pain control as the next step of treatment after the lack of clinical results of surgical and pharmacological methods normally used in the management of endometriosis and pelvic adhesions. MATERIALS AND METHOD: 18 women were treated between January 2010 - October 2013 in the Pain Clinic of the Department of Anaesthesiology and Intensive Care at the Centre for Postgraduate Education in Warsaw due to chronic pelvic pain syndrome related to either endometriosis or pelvic adhesions. During the previous step of management, both conservative and surgical treatments were completed without achieving satisfactory results. Initial constant pain severity was 3-9 points on the Numeric Rating Scale, while the reported paroxysmal pain level was 7-10. The pharmacological treatment implemented was based on oral gabapentinoids and antidepressants, aided by neurolytic block of ganglion of Walther, pudendal nerve blocks and topical treatment (5% lidocaine, 10% amitriptyline, 10% gabapentin). RESULTS: In 17 women, a significant reduction of both constant and paroxysmal pain was achieved, of which complete and permanent cessation of pain occurred in 6 cases. One patient experienced no improvement in the severity of her symptoms. CONCLUSIONS: The combination of pain management with pharmacological treatment, pudendal nerve blocks, neurolysis of ganglion impar (Walther) and topical preparations in cases of chronic pelvic pain syndrome seems to be adequate medical conduct after failed or otherwise ineffective causative therapy.


Assuntos
Anestésicos Locais/uso terapêutico , Antidepressivos/uso terapêutico , Dor Crônica/terapia , Manejo da Dor/métodos , Dor Pélvica/terapia , Adulto , Idoso , Bloqueio Nervoso Autônomo/instrumentação , Dor Crônica/tratamento farmacológico , Endometriose/cirurgia , Endometriose/terapia , Feminino , Humanos , Pessoa de Meia-Idade , Manejo da Dor/instrumentação , Dor Pélvica/tratamento farmacológico , Pelve/cirurgia , Polônia , Aderências Teciduais/cirurgia , Aderências Teciduais/terapia , Adulto Jovem
13.
Minerva Med ; 105(5): 333-51, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25028865

RESUMO

Over the three last decades, endosonography ultrasound (EUS) has evolved from a diagnostic tool to an interventional modality through cumulative advances in experience, knowledge, equipment, and devices. EUS-guided therapeutic procedures appear feasible and safe when performed in highly-experienced centers. This review covers the technical aspects, indications, and results of the most commonly performed procedures. Celiac plexus neurolysis and collection drainages are now well-established techniques and considered to be first-line treatments. Biliary and pancreatic EUS-guided drainages are, conversely, more challenging, and there is currently insufficient clinical evidence documenting their superiority over established practice. Well-designed prospective trials are thus needed in order to accurately assess this modality's risks and long-term outcomes compared to radiological or surgical techniques.


Assuntos
Anestésicos Locais/administração & dosagem , Bloqueio Nervoso Autônomo/métodos , Sistema Biliar/fisiopatologia , Plexo Celíaco , Drenagem/métodos , Endossonografia/métodos , Manejo da Dor/métodos , Pancreatopatias/complicações , Ultrassonografia de Intervenção/métodos , Abscesso Abdominal/complicações , Abscesso Abdominal/etiologia , Doença Aguda , Bloqueio Nervoso Autônomo/efeitos adversos , Bloqueio Nervoso Autônomo/instrumentação , Sistema Biliar/diagnóstico por imagem , Drenagem/instrumentação , Endossonografia/instrumentação , Desenho de Equipamento , Medicina Baseada em Evidências , Humanos , Dor/etiologia , Neoplasias Pancreáticas/complicações , Pancreatite/complicações , Qualidade de Vida , Ultrassonografia de Intervenção/instrumentação
14.
BMC Anesthesiol ; 14: 26, 2014 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-24725473

RESUMO

BACKGROUND: Stimulating catheters offer the possibility of delivering an electrical charge via the tip of the catheter. This may be advantageous as it allows verifying if the catheter tip is in close proximity to the target nerve, thereby increasing catheter performance. This prospective blinded cohort study was designed to investigate whether there is a correlation between the minimal electrical charge at the tip of the stimulating catheter, and the efficacy of the peripheral nerve block (PNB) catheter as determined by 24 h postoperative morphine consumption. METHODS: Forty adult patients with ASA physical health classification I-III scheduled for upper extremity surgery under combined continuous interscalene block and general anesthesia were studied. Six patients were excluded from analysis.After inserting a stimulating catheter as if it were a non-stimulating catheter for 2-5 cm through the needle, the minimal electrical charge necessary to obtain an appropriate motor response was determined. A loading dose of 20 mL ropivacaine 0.75% ropivacaine was then administered, and postoperative analgesia was provided by a continuous infusion of ropivacaine 0.2% 8 mL.h-1 via the brachial plexus catheter, and an intravenous morphine patient-controlled analgesia (PCA) device.Main outcome measures include the minimal electrical charge (MEC) at the tip of the stimulating catheter necessary to elicit an appropriate motor response, and the efficacy of the PNB catheter as determined by 24 h postoperative PCA morphine consumption. RESULTS: Mean (SD) [range] MEC at the tip of the stimulating catheter was 589 (1414) [30 - 5000] nC. Mean (SD) [range] 24 h morphine consumption was 8.9 (9.9) [0-29] mg. The correlation between the MEC and 24 h postoperative morphine consumption was Spearman's Rho rs = -0.26, 95% CI -0.56 to 0.09. CONCLUSION: We conclude that there is no proportional relation between MEC at the tip of the blindly inserted stimulating catheter and 24 h postoperative morphine consumption. TRIAL REGISTRATION: Trialregister.nl identifier: NTR2328.


Assuntos
Bloqueio Nervoso Autônomo/métodos , Bloqueio do Plexo Braquial/métodos , Dor Pós-Operatória/prevenção & controle , Adulto , Analgésicos Opioides/administração & dosagem , Bloqueio Nervoso Autônomo/instrumentação , Bloqueio do Plexo Braquial/instrumentação , Catéteres , Estudos de Coortes , Estimulação Elétrica/instrumentação , Estimulação Elétrica/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Morfina/administração & dosagem , Dor Pós-Operatória/diagnóstico , Estudos Prospectivos , Resultado do Tratamento
15.
Rev Esp Anestesiol Reanim ; 61(8): 454-6, 2014 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-24360738

RESUMO

Stellate ganglion block is a technique that is often used by anesthesiologists for the treatment of complex regional pain syndromes of the upper extremity. This technique interrupts cardiac sympathetic innervation and has been proposed as treatment for refractory arrhythmias. We present the case of a patient with arrhythmias that were refractory to pharmacological treatment, and were finally treated by continuous stellate ganglion block. Left stellate ganglion is a lynchpin of cardiac arrhythmias due to being a structure where the majority of postganglion sympathetic fibers responsible for preferentially innervating the atriventricular node, bundle of His and ventricular mass are originated, fundamentals in the origin and maintenance of ventricular arrhythmias.


Assuntos
Bloqueio Nervoso Autônomo/métodos , Sistema de Condução Cardíaco/fisiopatologia , Gânglio Estrelado/fisiopatologia , Taquicardia Ventricular/terapia , Ultrassonografia de Intervenção/métodos , Nó Atrioventricular/inervação , Bloqueio Nervoso Autônomo/instrumentação , Bupivacaína/administração & dosagem , Bupivacaína/uso terapêutico , Fármacos Cardiovasculares/uso terapêutico , Cateteres de Demora , Terapia Combinada , Contrapulsação , Desfibriladores Implantáveis , Resistência a Medicamentos , Cardioversão Elétrica , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Fibras Simpáticas Pós-Ganglionares/fisiopatologia , Taquicardia Ventricular/diagnóstico por imagem , Taquicardia Ventricular/tratamento farmacológico
16.
Anesth Analg ; 118(1): 225-9, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24247226

RESUMO

BACKGROUND: Ropivacaine is a long-acting local anesthetic used for continuous peripheral nerve catheter infusions. Catheters may remain in situ for prolonged time periods. In the present study, patients were enrolled to receive continuous peripheral nerve catheters with measurement of free serum ropivacaine concentrations. METHODS: Peripheral nerve catheters were placed for postoperative pain management in trauma patients and infused with ropivacaine 0.2% or bolused with 0.5%. Blood samples were obtained from each subject on days 0 (preinfusion), 3, 5, 7, 10, and every third day until catheter removal. Serum free ropivacaine concentrations were measured via high-performance liquid chromatography and were compared using the Wilcoxon signed rank test. RESULTS: One hundred thirty-three blood samples were analyzed in 35 patients; all serum free ropivacaine concentrations after infusion initiation (99 samples from 35 subjects) were below 0.34 mg/L (previously determined toxic threshold). The highest concentration achieved in a blood sample was 0.19 mg/L; all other values were <0.09 mg/L. The total amount of drug received during the study ranged from 1146 to 22,320 mg (median of 3722 mg). Catheters remained in situ for a median of 7 days (range: 3-23). From day 0 to 3 (preinfusion), 77% of the study participants had an increase in the serum free-fraction ropivacaine concentrations. The median concentration on day 3 was 0.025 mg/L (95% upper confidence limit for mean: 0.05, range: <0.01-0.19); P < 0.001 compared with preinfusion levels). From day 3 to 5, 68% of the participants had a decrease in the serum free ropivacaine concentrations (median level 0.016 mg/L [95% upper confidence limit for mean: 0.021] P = 0.007 for day 5 compared with day 3). CONCLUSIONS: In this study, free serum ropivacaine concentrations remained well below toxic values despite large amounts of drug administration in combat-wounded patients. The administration of continuous ropivacaine infusions over prolonged time periods, coupled with multiple drug boluses, did not produce toxic or near-toxic serum concentrations.


Assuntos
Amidas/administração & dosagem , Amidas/sangue , Anestésicos Locais/administração & dosagem , Anestésicos Locais/sangue , Bloqueio Nervoso Autônomo/métodos , Adulto , Amidas/efeitos adversos , Anestésicos Locais/efeitos adversos , Bloqueio Nervoso Autônomo/efeitos adversos , Bloqueio Nervoso Autônomo/instrumentação , Cateteres de Demora/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ropivacaina , Fatores de Tempo , Adulto Jovem
18.
Minerva Stomatol ; 62(11-12): 455-63, 2013.
Artigo em Inglês, Italiano | MEDLINE | ID: mdl-24270204

RESUMO

Needle breakage in the oral cavity during local anesthesia is a rare but possible complication. In the majority of cases this happens in the pterygomandibular space during an inferior alveolar nerve block and the causes are multifactorial. The treatment recommended is localization and removal of the extraneous body, as soon as possible, in a surgical setting so as to prevent possible migration of the metal fragment with consequent possible lesions to the surrounding anatomical structures. We present four case studies that have occurred since 2011.


Assuntos
Anestesia Dentária/instrumentação , Bloqueio Nervoso Autônomo/instrumentação , Corpos Estranhos/etiologia , Mandíbula , Agulhas , Adulto , Idoso , Apicectomia , Desenho de Equipamento , Falha de Equipamento , Corpos Estranhos/cirurgia , Humanos , Masculino , Mandíbula/diagnóstico por imagem , Agulhas/normas , Tomografia Computadorizada por Raios X
19.
Rev. Soc. Esp. Dolor ; 20(5): 216-220, sept.-oct. 2013. tab
Artigo em Espanhol | IBECS | ID: ibc-116800

RESUMO

Introducción: Los intentos repetidos de punción son factores de riesgo para la aparición de complicaciones neurológicas secundarias a la práctica de la analgesia espinal y aumentan la ansiedad del paciente. El objetivo de este estudio es determinar qué factores son mejores predictores de la colocación dificultosa del catéter epidural en la paciente obstétrica. Material y método: Estudio observacional y prospectivo en 120 gestantes a término que solicitan la analgesia epidural para el trabajo de parto. Se recogen variables demográficas y antecedentes de anestesia espinal previa no exitosa o considerada dificultosa por la paciente. Se identifican variables anatómicas y se clasifica la calidad de los puntos de referencia anatómicos según los criterios publicados por Chien en cuatro grados. Las condiciones de la técnica y la experiencia del anestesiólogo son similares en todos casos. Consideramos punción dificultosa si se necesita más de una punción en la piel o una punción pero más de un cambio de dirección de aguja en el espacio interespinoso. Se recoge el éxito obtenido y las complicaciones de la técnica. Resultados: Fueron calificadas de punción difícil según los criterios del estudio en el 36,67 % de los casos. En la mayoría de los casos la técnica fue efectiva obteniendo una adecuada analgesia. La incidencia de repunción epidural fue de 5 %. En las pacientes clasificadas en el grado 4, la tasa de punción epidural considerada dificultosa supuso un 90 %, necesitando en el 80 % de esos casos 3 o más intentos. En las pacientes con antecedentes personales de técnica neuroaxial dificultosa se encontró dificultad de punción epidural en un 28,57 % de los casos. El hábito corporal no tuvo efecto significativo sobre la tasa de éxito con el primer intento. Discusión: Nuestro estudio representa una buena estimación de la dificultad técnica de un bloqueo neuroaxial. Seria difícil saber si los datos reflejados serían extrapolables a la realización de la técnica en decúbito lateral, donde los puntos de referencia anatómicos son más difíciles de identificar. Conclusiones: Nuestra recogida concluye que el método más fiable para determinar de antemano la posibilidad de una dificultad técnica de colocación del catéter epidural lumbar es un examen de la espalda de la paciente para identificar la calidad de los puntos de referencia anatómicos e identificar la deformidad obvia de la columna vertebral (AU)


Introduction: Repeated attempts punctureare risk factors for the appearance of neurologic complications caused by the practice of spinal analgesia and increase patient anxiety. The purpose of this study is to determine which factor sare better predictors of difficult epidural catheter placement in the obstetric patient. Material and methods: Prospective observational study in 120 pregnant women at term who request edepidural analgesia during labor. Demographic variables and history of difficult or unsuccessful spinal anesthesia were collected. Anatomical variables were identified and the quality of anatomical landmarks was classified according to criteria published by Chien in four grades. The conditions of the technique and the experience of anesthesiologists were similar in all cases. It was considered as difficult puncture that in which was made more than one attempt on skin or more than one change of direction with the epidural needle in interspinous space.We collected the successand complications of the technique. Results: 36.67 % of cases were classified as difficult punctures according to the criteria of the study. In most cases the technique was effective obtaining asuccessful analgesia. The incidence of repeat epidural puncture was 5 %. In patients classified in grade 4, the percentage of difficult epidural puncture was 90 %, requiring in 80 % of the cases 3 or more attempts. In patients with a history of difficult neuraxial technique in 28.57 % of the cases was found difficulty in epidural puncture. Body habitus had no significant effect on the rate success in first attempt. Discussion: Our study represents a good estimationof a difficult neuraxial blockade. It would bedifficult to know if there flected datawould be applicable to the lateral decubitus technique where anatomical landmarksare more difficult to identify. Conclusions: Our study concludes thatt he most reliable method to predict the possibility of a technical difficulty in the placement of lumbar epidural catheter, is the examination of the back of the patient to identify the quality of anatomical landmarks and identify obvious deformities of the spine (AU)


Assuntos
Humanos , Feminino , Gravidez , Adulto , Analgesia Obstétrica/instrumentação , Analgesia Obstétrica/métodos , Analgesia Obstétrica , Bloqueio Nervoso Autônomo/instrumentação , Bloqueio Nervoso Autônomo/métodos , Bloqueio Nervoso Autônomo , Bloqueio Nervoso/métodos , Bloqueio Nervoso/tendências , Bloqueio Nervoso , Analgesia Obstétrica/psicologia , Analgesia Obstétrica/tendências , Infusão Espinal , Estudos Prospectivos
20.
Rev. Soc. Esp. Dolor ; 20(2): 50-54, mar.-abr. 2013. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-110631

RESUMO

Introducción: El fenómeno de Raynaud es un trastorno vascular, frecuente en la población general, que consiste en la aparición paroxística de espasmo vascular distal, en pequeñas arterias y arteriolas cutáneas de las extremidades, con escasa repercusión sistémica. Existen bases anatómicas y fisiológicas para producir un bloqueo simpático selectivo utilizando agentes neurolíticos en los ganglios torácicos T2 y T3, considerados estaciones sinápticas que se distribuyen en el miembro superior. Objetivo: Determinar la eficacia del bloqueo neurolítico del tercer ganglio dorsal en el síndrome de Raynaud de una serie de casos. Material y métodos: Se realizó la revisión de expedientes de una serie de ocho casos con fenómeno de Raynaud de causa multifactorial, en la Clínica del Dolor de la Unidad Médica de Alta Especialidad Monterrey; Nuevo León, México. Casos: Ocho casos de 41 a 72 años de edad con fenómeno de Raynaud, tratados médicamente, a los cuales se les realizaron simpaticolisis del tercer ganglio dorsal. Conclusiones: El fenómeno de Raynaud tiene una prevalencia que va del 1 al 25%, en este hay una actividad simpática aumentada por lo que al realizar una simpaticolisis selectiva se logra mejorar el dolor isquémico, el cual está determinado por la insuficiencia total o parcial en el aporte de oxígeno a los tejidos, además de que tenemos bases anatómicas y fisiológicas para limitar el bloqueo a los ganglios T2 y T3, considerados como las estaciones sinápticas que interrumpen los impulsos que se distribuyen en el miembro superior, siendo por tanto más selectivos y con menores efectos adversos para el paciente (AU)


Background: Raynaud’s phenomenon, a vascular disorder that is common in the general population, consists of paroxysmal onset distal vasospasm in small cutaneous arteries and arterioles of extremities, usually with little systemic impact. There are anatomical and physiological bases to produce a selective sympathetic block ad using neurolytic agents in the thoracic ganglia T2 and T3 considered synaptic stations that are distributed in the upper limb. Objective: The objective of this work was to determine the efficacy of neurolytic block of the third dorsal ganglion due to Raynaud’s syndrome in a series of cases. Material and methods: A review of records of eight cases with Raynaud’s phenomenon that presented multifactorial origin were conducted on Clinic of the Pain located in the Unidad Médica de Alta Especialidad, Monterrey Nuevo León, México. Cases: Eight patients from 41 to 72 years old were medically treated for Raynaud’s phenomenon using sympathicolysis dorsal third node. Conclusions: Raynaud’s phenomenon with a prevalence ranging from 1 to 25% has an increased sympathetic activity. The ischemic pain that is determined by total or partial failure in the oxygen transport to tissues was reduced in these patients by performing a selective sympathicolysis in the thoracic ganglia T2 and T3 considered synaptic stations that are distributed in the upper limb. It was demonstrated in this study that this treatment is selective with less adverse effects to the patients (AU)


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Bloqueio Nervoso/métodos , Bloqueio Nervoso Autônomo/instrumentação , Bloqueio Nervoso Autônomo/métodos , Bloqueio Nervoso Autônomo , Sistema Nervoso Simpático , Doença de Raynaud/tratamento farmacológico , Clínicas de Dor/normas , Clínicas de Dor , Gânglios Espinais , Gânglios Espinais/cirurgia
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