[A rapid method standardizing cholagogue substances on mice]. / Bystryi metod standartizatsii zhelchegonnykh sredstv na myshakh

The authors described a rapid method of selection and quantitative assessment of the specific activity of substances (insulin, chologon and mebethizol: 2-mercaptobenzthiazol with a cholagogue action of mice. The gall bladder obtained from the animals was weighed with and wihtout the bile; it was thus possible to determine the amount of bile accumulated in the gall bladder under the action of the agents under study during a definite period of time. The method described may be used for pharmacological screening.