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World J Gastroenterol ; 24(39): 4489-4498, 2018 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-30356997

RESUMO

AIM: To evaluate the effectiveness and safety of combined ursodeoxycholic acid and percutaneous transhepatic balloon dilation for management of gallstones after expulsion of common bile duct (CBD) stones. METHODS: From April 2014 to May 2016, 15 consecutive patients (6 men and 9 women) aged 45-86 (mean, 69.07 ± 9.91) years suffering from CBD stones associated with gallstones were evaluated. Good gallbladder contraction function was confirmed by type B ultrasonography. Dilation of the CBD and cystic duct was detected. Percutaneous transhepatic balloon dilation of the papilla was performed, ursodeoxycholic acid was administered, and all patients had a high-fat diet. All subjects underwent repeated cholangiography, and percutaneous transhepatic removal was carried out in patients with secondary CBD stones originating from the gallbladder. RESULTS: All patients underwent percutaneous transhepatic balloon dilation with a primary success rate of 100%. The combined therapy was successful in 86.7% of patients with concomitant CBD stones and gallstones. No remaining stones were detected in the gallbladder. Transient adverse events include abdominal pain (n = 1), abdominal distension (n = 1), and fever (n = 1). Complications were treated successfully via nonsurgical management without long-term complications. No procedure-related mortality occurred. CONCLUSION: For patients with concomitant CBD stones and gallstones, after percutaneous transhepatic removal of primary CBD stones, oral ursodeoxycholic acid and a high-fat diet followed by percutaneous transhepatic removal of secondary CBD stones appear to be a feasible and effective option for management of gallstones.


Assuntos
Colagogos e Coleréticos/uso terapêutico , Coledocolitíase/terapia , Dilatação/métodos , Cálculos Biliares/terapia , Ácido Ursodesoxicólico/uso terapêutico , Idoso , Idoso de 80 Anos ou mais , Cateterismo/efeitos adversos , Cateterismo/instrumentação , Cateterismo/métodos , Colangiografia , Coledocolitíase/diagnóstico por imagem , Coledocolitíase/dietoterapia , Terapia Combinada/efeitos adversos , Terapia Combinada/métodos , Ducto Colédoco/diagnóstico por imagem , Dieta Hiperlipídica , Dilatação/efeitos adversos , Dilatação/instrumentação , Endoscopia do Sistema Digestório , Estudos de Viabilidade , Feminino , Vesícula Biliar/diagnóstico por imagem , Cálculos Biliares/diagnóstico por imagem , Cálculos Biliares/dietoterapia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Ácido Ursodesoxicólico/efeitos adversos
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