1.
Cancer Cell
; 17(4): 315-6, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20385356
RESUMO
Transcription factors have proven to be difficult targets for the development of small-molecule drugs. In this issue of Cancer Cell, Cerchietti et al. identify and characterize a specific, small-molecule inhibitor of BCL6, an oncogenic transcriptional repressor, that has high clinical promise for treating diffuse large B cell lymphoma.