1.
Chem Pharm Bull (Tokyo)
; 49(11): 1406-11, 2001 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11724230
RESUMO
In our search for novel anti-human immunodeficiency virus (HIV)-1 agents, 14 delavirdine analogues were synthesized and evaluated as potential anti-HIV-1 agents in cell-based assays. Compound 1Aa exhibited potent and selective anti-HIV-1 activity in acutely infected MT4 cells, with effective concentration (EC50) values in the submicromolar range.
