Granuloma aséptico facial idiopático: revisión actualizada de las dificultades diagnósticas y terapéuticas / Idiopathic Facial Aseptic Granuloma: Updated Review of Diagnostic and Therapeutic Difficulties

El granuloma aséptico facial idiopático (GAFI) es una patología específica de la edad pediátrica caracterizada por la aparición de nódulos rojizos asintomáticos en la región facial. Su etiopatogenia es aún motivo de discusión, aunque la literatura actual orienta a que se encontraría dentro del espectro de la rosácea infantil. Tiene una evolución crónica pero benigna, y hay publicaciones que documentan la resolución espontánea de las lesiones en menos de un año. A pesar de no tener un tratamiento bien definido, se prefiere que sea conservador y se eviten las intervenciones agresivas

Idiopathic facial aseptic granuloma is a pediatric skin condition involving asymptomatic reddish nodules. The etiology and pathogenesis is still under discussion, although the literature tends to place this condition within the spectrum of childhood rosaceas. The clinical course is chronic but benign, and cases have been reported to resolve spontaneously in less than a year. Even though no well-defined treatment has emerged, a conservative approach that avoids aggressive therapies is preferred

Granuloma aséptico facial idiopático. Utilidad de la ecografía cutánea / Idiopathic facial aseptic granuloma: usefulness of cutaneous ultrasound

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Physiological and lifestyle factors contributing to risk and severity of peri-orbital dark circles in the Brazilian population

AbstractBACKGROUND:Peri-orbital dark circles are a cosmetic concern worldwide, and have been attributed to hyperpigmentation from allergy or atopic dermatitis, blood stasis, structural shadowing effects, and a thin epidermis/dermis under the eye. It is of interest to better understand lifestyle and demographic risk factors and the relative impact of melanin, blood and epidermal/dermal factors on the severity of Peri-orbital dark circles.OBJECTIVE:To compare by non-invasive imaging the impact of biological factors to a visual grading scale for Peri-orbital dark circles, and test the correlation of various demographic factors with Peri-orbital dark circles.METHODS:Subjects completed a lifestyle and health survey, and Peri-orbital dark circles severity was evaluated using standardized photographs. Hyperspectral image analysis was used to assess the contributions of melanin, blood volume, degree of blood oxygen saturation, and dermal scattering.RESULTS:Family history was the most significant risk factor for Peri-orbital dark circles. The average age of onset was 24 years, and earlier onset correlated with higher severity scores. Asthma was significantly associated with Peri-orbital dark circles scores, but self-reported allergy was not. In this study, sleep was not correlated with Peri-orbital dark circles scores. Hyperspectral imaging indicated that melanin was the dominant correlate for Peri-orbital dark circles severity, while oxygen saturation was secondary. The difference between under-eye and cheek measurements for ΔL*and ΔE* were the most significant instrumental parameters correlated with visual assessment of Peri-orbital dark circles severity.CONCLUSION:Although typically associated with lack of sleep, risk of Peri-orbital dark circles is primarily hereditary. The main factors contributing to the appearance of Peri-orbital dark circles are melanin and (deoxygenated) blood.

Quistes miliares en placa / Milia en plaque

Los quistes miliares en placa son una variante de quistes miliares primarios poco frecuente, o al menos poco descrita en la literatura. Aportamos el caso de una mujer con lesiones bilaterales en la región retroauricular y en párpado superior derecho y revisamos las localizaciones y los tratamientos utilizados en el resto de los casos publicados

Milia en plaque is an unusual variant of primary milia, possibly underreported. We report the case of a woman with this disorder occurring bilaterally in the retroauricular region and on the right upper eyelid. The previous reported cases, their locations and different treatments are rewied

Púrpura fulminans / Purpura fulminans

Se reporta el caso de una mujer de 49 años con lesiones purpúricas diseminadas de aparición súbita y pruebas de coagulación normales. El cuadro se instaló después de intervención quirúrgica porcarcinoma cervico-uterino; hubo resolución con presencia de secuelas

Granuloma facial eosinofílico / Eosinophilic facial granuloma

Se presenta el caso de una mujer de 20 años con lesiones granulomatosas periorbitarias, asintomáticas de diez años de evolución. La histología mostró un infiltrado granulomatoso con intensa eosinofilia. La paciente respondió excelentemente a la diamino difenil sulfona. Se comenta la rareza de esta entidad, la inusual morfología de las lesiones y la notable respuesta a la DDS