1.
Chem Commun (Camb)
; 51(76): 14350-3, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26267039
RESUMO
Circular dichroism spectroscopy has been explored for detection of methyltransferase activity and inhibition based on DNA-induced chiroplasmonic assemblies of gold nanoparticles and endonuclease HpaII. Good accuracy, precision and sensitivity are obtained in complex matrices such as human serum samples, which is significant for clinical diagnosis and drug development.