Maxillomandibular deformity in a canine with fibrous osteodystrophy secondary to chronic kidney disease

Background: Cases of renal fibrous osteodystrophy are usually associated with nutritional causes, which of renal causesare considered uncommon in dogs. This disorder is characterized by the intense proliferation of fibrous connective tissue inbones, impairing bone stiffness. The aim of this study was to report a case of fibrous osteodystrophy secondary to chronickidney disease in a canine with a “rubber jaw” facial deformity.Case: A 4-year-old male unneutered mongrel dog weighing 5.2 kg had a history of apathy, progressive weight loss andvomiting for one month, and polyuria and polydipsia for more than three months. In addition, the owner complained aboutthe deformed appearance in the muzzle region of the animal, which was evidenced flexibility of the same, with a displacement of the mandible and maxilla on physical examination, similar to the “rubber jaw”. Blood tests revealed macrocyticanemia, elevated total plasma proteins, and lymphopenia-associated neutrophilia, as well as hyperphosphatemia (24 mg/dL), uremia (283.6 mg/dL) and increased creatinine (8.6 mg/dL), ALT (143.2 UI/L) and alkaline phosphatase (3222.2UI/L), while calcium (8.8 mg/dL) and albumin (1.9 g/dL) were decreased. A serological test for visceral leishmaniasis wasalso performed, which was negative. Abdominal ultrasound imaging revealed kidneys with alterations in tissue architecture, increased thickness and complete loss of cortico-medullary relationship, while the parathyroid gland was enlargedand spindle-shaped. Cranial radiography showed marked radiopacity of the bilateral maxillary bones, with destructionof the nasal, turbinate and frontal bones, as well as loosening of the teeth and destruction of the mandibular bone matrix,characterizing an aspect of “rubber jaw”. Based on the history, history and evidence of azotemia, hyperphosphatemia andloss of facial bone density, the diagnosis of fibrous osteodystrophy secondary to chronic kidney...(AU)

Maxillomandibular deformity in a canine with fibrous osteodystrophy secondary to chronic kidney disease

Background: Cases of renal fibrous osteodystrophy are usually associated with nutritional causes, which of renal causesare considered uncommon in dogs. This disorder is characterized by the intense proliferation of fibrous connective tissue inbones, impairing bone stiffness. The aim of this study was to report a case of fibrous osteodystrophy secondary to chronickidney disease in a canine with a “rubber jaw” facial deformity.Case: A 4-year-old male unneutered mongrel dog weighing 5.2 kg had a history of apathy, progressive weight loss andvomiting for one month, and polyuria and polydipsia for more than three months. In addition, the owner complained aboutthe deformed appearance in the muzzle region of the animal, which was evidenced flexibility of the same, with a displacement of the mandible and maxilla on physical examination, similar to the “rubber jaw”. Blood tests revealed macrocyticanemia, elevated total plasma proteins, and lymphopenia-associated neutrophilia, as well as hyperphosphatemia (24 mg/dL), uremia (283.6 mg/dL) and increased creatinine (8.6 mg/dL), ALT (143.2 UI/L) and alkaline phosphatase (3222.2UI/L), while calcium (8.8 mg/dL) and albumin (1.9 g/dL) were decreased. A serological test for visceral leishmaniasis wasalso performed, which was negative. Abdominal ultrasound imaging revealed kidneys with alterations in tissue architecture, increased thickness and complete loss of cortico-medullary relationship, while the parathyroid gland was enlargedand spindle-shaped. Cranial radiography showed marked radiopacity of the bilateral maxillary bones, with destructionof the nasal, turbinate and frontal bones, as well as loosening of the teeth and destruction of the mandibular bone matrix,characterizing an aspect of “rubber jaw”. Based on the history, history and evidence of azotemia, hyperphosphatemia andloss of facial bone density, the diagnosis of fibrous osteodystrophy secondary to chronic kidney...

Aplicacao de Calcarea phosphorica na osteodistrofia fibrosa em frangos de corte / Calcarea phosphorica utilization in fibrous osteodystrophy in young chicken

Pintinhos de um dia da linhagem Cobb foram distribuidosem 6 grupos experimentais com 4 repeticoes, sendo 2 de cada sexo. Cada grupo recebeu Arsenicum album 30 CH, nosodio P.B.S. 30 CH, Calcarea phosphorica 30 CH, Arsenicum album + nosodio P.B.S. 30 CH e Colibacillinum C200, respectivamente e o ultimo grupo foi o controle que recebeu agua. Estes animais foram tratados com racao de milho e farelo, "ad libidum" e receberam os tratamentos na agua de beber. No decorrer da experimentacao, as aves apresentaram a sindrome da oeteodistrofia fibrosa por baixa disponibilidade de calcio e fosforo, na racao. Porem, as aves tratadas com Calcarea phosphorica 30 CH tiveram o seu peso dentro do normal, nao apresentando sintomas caracteristicos da deficiencia de fosforo. Por outro lado, os outros grupos nao foram beneficiados pelos tratamentos recebidos apresentando deficiencia no dsenvolvimento e ganho do peso

Aplicacao de Calcarea phosphorica na osteodistrofia fibrosa em frangos de corte / Calcarea phosphorica utilization in fibrous osteodystrophy in young chicken

Pintinhos de um dia da linhagem Cobb foram distribuidosem 6 grupos experimentais com 4 repeticoes, sendo 2 de cada sexo. Cada grupo recebeu Arsenicum album 30 CH, nosodio P.B.S. 30 CH, Calcarea phosphorica 30 CH, Arsenicum album + nosodio P.B.S. 30 CH e Colibacillinum C200, respectivamente e o ultimo grupo foi o controle que recebeu agua. Estes animais foram tratados com racao de milho e farelo, "ad libidum" e receberam os tratamentos na agua de beber. No decorrer da experimentacao, as aves apresentaram a sindrome da oeteodistrofia fibrosa por baixa disponibilidade de calcio e fosforo, na racao. Porem, as aves tratadas com Calcarea phosphorica 30 CH tiveram o seu peso dentro do normal, nao apresentando sintomas caracteristicos da deficiencia de fosforo. Por outro lado, os outros grupos nao foram beneficiados pelos tratamentos recebidos apresentando deficiencia no dsenvolvimento e ganho do peso