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2.
Thromb Res ; 130 Suppl 1: S56-8, 2012 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23026664

RESUMO

Mondor's disease (MD) is a rare and self-limited benign disease first described in 1939. Originally its clinical presentation was a superficial vein thrombosis (SVT) without contiguous skin inflammation of the chest wall veins. Over time its definition has evolved and now also includes subcutaneous thrombosis of the dorsal vein of the penis but also retractile scarring of the fascia after breast surgery without concomitant SVT. In all cases clinical examination constitutes the first step of diagnostic management. It is followed by an ultrasound exploration (US) to search for a thrombus. In about half of all cases the disease is considered as idiopathic and cancer is rare. Whatever the location considered, the follow-up is usually uneventful with low rates of recurrence and of subsequent cancer. Treatment is debated and ranges from therapeutic abstention to anticoagulants or even surgery. It is likely that the new locations and mechanisms (without thrombosis) of the MD have lead to the constitution of a heterogeneous entity precluding from a consensual mode of care.


Assuntos
Doenças Mamárias , Doenças do Pênis , Doenças Torácicas , Trombose Venosa , Anticoagulantes/uso terapêutico , Doenças Mamárias/classificação , Doenças Mamárias/diagnóstico , Doenças Mamárias/epidemiologia , Doenças Mamárias/história , Doenças Mamárias/terapia , Feminino , História do Século XX , História do Século XXI , Humanos , Masculino , Mamografia , Doenças do Pênis/classificação , Doenças do Pênis/diagnóstico , Doenças do Pênis/epidemiologia , Doenças do Pênis/história , Doenças do Pênis/terapia , Valor Preditivo dos Testes , Recidiva , Fatores de Risco , Doenças Torácicas/classificação , Doenças Torácicas/diagnóstico , Doenças Torácicas/epidemiologia , Doenças Torácicas/história , Doenças Torácicas/terapia , Trombectomia , Resultado do Tratamento , Ultrassonografia Doppler em Cores , Ultrassonografia Doppler de Pulso , Trombose Venosa/classificação , Trombose Venosa/diagnóstico , Trombose Venosa/epidemiologia , Trombose Venosa/história , Trombose Venosa/terapia
4.
Br J Dermatol ; 166(2): 247-51, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21967192

RESUMO

For many years it has been the work of Buschke and Löwenstein that has justified calling the exophytic, locally destructive tumour of the anogenital mucosal surface 'giant condyloma of Buschke and Löwenstein' or GCBL. In order to investigate the early history of this rare disease we examined the writings of the barber-surgeon Wilhelm Fabry (1560-1634) who had a serious interest in dermatological disorders and their treatment. We analysed Fabry's 600 Latin case reports and identified the case of a 'monstrous penile tumour'. We then translated this text into English and compared it point by point with later publications. This was followed by a cursory review of surgical treatises from the 16th to the 18th centuries. In 1614 Fabry described and depicted a tumour of the penis; the clinical characteristics (gradual formation of a warty lesion, considerable size, invasive growth, absence of metastases) indicated it was a giant condyloma. His mention of the urethral fistulization enables discrimination from 'common' condylomata acuminata, and the survival period of 10 years after amputation allows exclusion of a 'true' carcinoma. This report is singular among 17th-century case histories. The neoplasias described 300 years later are most probably biologically identical. Thus, Fabry's is the first clinical report; the histological classification, however, belongs to Buschke and Löwenstein. From now on the disease should be designated with the eponym giant condyloma of Fabry-Buschke-Löwenstein or GCFBL.


Assuntos
Condiloma Acuminado/história , Doenças do Pênis/história , Cirurgiões Barbeiros/história , Condiloma Acuminado/patologia , Epônimos , Alemanha , História do Século XVI , História do Século XVII , História do Século XIX , História do Século XX , Humanos , Masculino , Doenças do Pênis/patologia , Procedimentos Cirúrgicos Urológicos Masculinos/história
5.
Am J Dermatopathol ; 28(6): 526-36, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17122499

RESUMO

In 1925 Abraham Buschke and Ludwig Loewenstein described a neoplasm of the penis (carcinomähnliche condylomata acuminata des penis), which, to them, bore resemblances to common condyloma acuminatum and squamous cell carcinoma, but it had histopathologic and clinical characteristics that differed from these 2 proliferations. Later Lauren V. Ackerman described a similar neoplasm of the oral mucosa that he termed "verrucous carcinoma." I have previously reviewed that neoplasm, now referred to as "oral verrucous carcinoma of Ackerman." Still later Aird and his colleagues described a unique neoplasm of the foot, "carcinoma cuniculatum." These 3 have been grouped generically as "verrucous carcinoma." Verrucous carcinomas occur at many sites including the female genitalia and the aerodigestive system. This report will synopsize the lives of Abraham Buschke and Ludwig Loewenstein, review their original articles, and mention the changing concepts over time concerning condylomata, particularly large condylomata. Some other reports of giant condyloma (verrucous carcinoma of the penis) will be discussed, emphasizing the histopathology of this neoplasm and its differentiation from "warty-like" carcinomas of the penis. Verrucous carcinoma of other sites and epithelioma (carcinoma) cuniculatum will not be discussed.


Assuntos
Condiloma Acuminado/história , Epônimos , Doenças do Pênis/história , Condiloma Acuminado/patologia , Dermatologia/história , Alemanha , História do Século XX , Humanos , Masculino , Patologia Cirúrgica/história , Doenças do Pênis/patologia
6.
Postgrad Med J ; 81(957): 413-8, 2005 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15998814

RESUMO

Surgeons of the Royal Navy during the Napoleonic and revolutionary wars, between 1793 and 1815, were solely responsible for all health care of the officers, men, and boys of their ships. This paper examines the genitourinary medicine and surgery encountered by the naval surgeons at the time of Nelson. Primary sources are examined to explore the presentation, case mix, and management of genitourinary disease during this period. A general overview is given of the life and work of the Royal Naval surgeons at the end of the 18th century. The documents that were examined contained 39 surgeon's journals, these were written by 26 surgeons on 13 different ships. The journals contained 446 presentations to the sick list of men with genitourinary symptoms. The presenting symptoms are grouped together under the following headings; venereal disease, penile pathology, scrotal pain and swelling, urinary symptoms and retention, stone disease and trauma. Examination of these journals permits a glimpse of medical life in the Royal Navy during the time of Nelson. The case load and management of genitourinary disease shows the diversity of presentation to these surgeons.


Assuntos
Cirurgia Geral/história , Doenças Urogenitais Masculinas/história , Medicina Naval/história , Genitália Masculina/lesões , História do Século XVIII , História do Século XIX , Humanos , Masculino , Prontuários Médicos , Doenças do Pênis/história , Infecções Sexualmente Transmissíveis/história , Reino Unido , Transtornos Urinários/história
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