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2.
Med Secoli ; 23(3): 991-1013, 2011.
Artigo em Italiano | MEDLINE | ID: mdl-23057209

RESUMO

Since Antiquity, the observation of matter and its composition has been fascinating for the human mind. It represented the core of philosophical studies since the atomistic theory by Leucippus and Democritus, as well as of the opposed theory of elements by Empedocles, Plato and Aristoteles. Research on the atom, on its spontaneous or artificial disgregation, on the practical application of radioactive substances has strongly influenced daily life and the development of knowledge. Products containing radioactive substances have been used, often without regulation or control, in many scientific fields, as well as in medicine and cosmetics.


Assuntos
Elementos Radioativos/história , Radioatividade , Radiografia/história , Radioterapia/história , Química/história , Qualidade de Produtos para o Consumidor , Cosméticos/história , Elementos Radioativos/uso terapêutico , Física Médica/história , História do Século XV , História do Século XVI , História do Século XVIII , História do Século XIX , História do Século XX , História do Século XXI , História Antiga , História Medieval , Física/história , Liberação Nociva de Radioativos/história , Liberação Nociva de Radioativos/psicologia , Risco
3.
Rheumatol Int ; 27(8): 703-13, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17203297

RESUMO

This study investigates the effects of radon (plus CO2) baths on RA in contrast to artificial CO2 baths in RA rehabilitation using a double-blinded trial enrolling 134 randomised patients of an in-patient rehabilitative programme (further 73 consecutive non-randomised patients are not reported here). The outcomes were limitations in occupational context/daily living (main outcome), pain, medication and further quantities. These were measured before the start, after the end of treatment and quarterly in the year thereafter. Repeated-measures analysis of covariance (RM-ANCOVA) of the intent-to-treat population was performed with group main effects (GME) and group x course interactions (G x C) reported. Hierarchically ordered hypotheses ensured the adherence of the nominal significance level. The superiority of the radon treatment was found regarding the main outcome (RM-ANCOVA until 12 months: p(GME) = 0.15, p(G x C) = 0.033). Consumption of steroids (p(GME) = 0.064, p(G x C) = 0.025) and NSAIDs (p(GME) = 0.035, p(G x C) = 0.008) were significantly reduced. The results suggest beneficial long-term effects of radon baths as adjunct to a multimodal rehabilitative treatment of RA.


Assuntos
Artrite Reumatoide/radioterapia , Balneologia/métodos , Elementos Radioativos/uso terapêutico , Águas Minerais/uso terapêutico , Radônio/uso terapêutico , Atividades Cotidianas , Adulto , Idoso , Dióxido de Carbono/uso terapêutico , Método Duplo-Cego , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Resultado do Tratamento
5.
Acta Otorhinolaryngol Ital ; 20(4 Suppl 63): 1-13, 2000 Aug.
Artigo em Italiano | MEDLINE | ID: mdl-11234440

RESUMO

The objective of the study was to test the effects of inhalation crenotherapy using the radioactive, fluoridated oligomineral waters from the Merano Spa on both subjects with specific upper respiratory tract phlogosis and normal subjects. The double-blind study was performed on a population of 27 adults of both sexes treated with radioactive-fluoridated water (group A) and 20 subjects, suffering from the same chronic catarrh pathology, selected with the same criteria but treated with inhalation of steam and an aerosol using drinking water from the municipal water supply (group C). In addition, a group of 13 subjects--which in terms of age and sex were statistically comparable to groups A and C but who did not show any signs of acute or chronic upper respiratory tract pathologies (group B) were also treated with the radioactive-fluoridated waters. All subjects included in the study underwent the following tests before and after the cycle of crenotherapy: Objective E.N.T. examination. Computerized Active Anterior Rhinomanometry. Detection of the ciliary mucous transport (CMT) time. Nasal cytology. Physical and immunochemical examination of the nasal mucous. The results of this study--seen in the trend in some parameters monitored both before and after the cycle of crenotherapy using Merano Spa water--clearly show that that the crenotherapy studied had an effect on aspecific chronic phlogosis of the upper respiratory tract. In fact, among other things, group A showed decreased nasal resistance, increased nasal respiratory flow, normalized mucociliary transport, decreased bacterial flora and an increased number of plasma cells in the rhinocytogram. In addition there was an increase in the following values in the nasal mucous: Albumin, non-secretory Immunoglobulin and the secretory portion of secretory Immunoglobulin A. None of these variations are seen in the results from the control group treated with municipal drinking water. After treatment with Merano spa water, the pathology-free subjects showed variations in the parameters in line with those found for group A. This biological reality can most likely be attributed to the favorable response of the respiratory mucosa, promoting anti-infection defenses.


Assuntos
Balneologia/métodos , Elementos Radioativos/uso terapêutico , Fluoretos/uso terapêutico , Minerais/uso terapêutico , Doenças Respiratórias/terapia , Doença Aguda , Administração por Inalação , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Método Duplo-Cego , Feminino , Humanos , Masculino , Manometria , Pessoa de Meia-Idade , Depuração Mucociliar/fisiologia , Mucosa Nasal/fisiologia , Doenças Respiratórias/diagnóstico , Resultado do Tratamento
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