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BMJ Case Rep ; 16(12)2023 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-38129082

RESUMO

Drug-induced nephrolithiasis is an important consideration in recurrent stone formers with polypharmacy. While felbamate nephrolithiasis has previously been published in the paediatric population, we present the oldest published case of a felbamate stone in an adult, a man in his 30s with Lennox-Gastaut syndrome. Even with moderate dosing, high drug serum levels can occur. Performing at least one stone analysis remains a critical component to care in these patients. Urologists should have a high index of suspicion for drug stone when stone analysis returns indeterminate characterisation in the absence of infection. Close communication with neurology is key to preventing recurrent stone disease.


Assuntos
Epilepsia , Felbamato , Nefrolitíase , Urolitíase , Adulto , Humanos , Masculino , Anticonvulsivantes/uso terapêutico , Epilepsia/tratamento farmacológico , Felbamato/efeitos adversos , Fenilcarbamatos/uso terapêutico , Propilenoglicóis , Urolitíase/induzido quimicamente , Urolitíase/tratamento farmacológico
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