RESUMO
BACKGROUND: Laser therapy is reported to be clinically effective for improving microcirculation, rheological properties and blood lipid profiles despite the lack of certainty on the mechanism. OBJECTIVE: This study intends to provide methods to drop blood lipid level of hyperlipidemia samples by low-intensity laser irradiation therapy and provide reasoning of mechanism. METHODS: Twenty whole blood samples of high level of lipids profile are irradiated by 405 nm low-intensity laser at 12 J/cm2 twice a day for 3 days and compared with normal lipids profile group. Then whole blood sample are centrifuged to obtain result of erythrocyte for further interpretation. Multi-scan spectrum microplate reader is used to measure absorption spectrum and data is analyzed by software SPSS 14.0. RESULTS: Results show that after 405 nm low-intensity laser irradiation, whole blood samples of high lipid level statistically have higher absorbance peak value than normal samples while erythrocyte samples have lower absorbance peak value. CONCLUSIONS: From the divergence of absorption peak value change after low-intensity laser irradiation for whole blood sample and erythrocyte, we suspect that low level laser irradiation affects the enzymes activity of lipid metabolism, improves the cholesterol balance of plasma and cytoplasm in erythrocyte, and decreases aggregation of the erythrocyte.
Assuntos
Eritrócitos/efeitos da radiação , Hiperlipidemias/radioterapia , Terapia com Luz de Baixa Intensidade/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Técnicas In Vitro , Masculino , Pessoa de Meia-Idade , Análise EspectralRESUMO
The impact of intravenous laser irradiation of blood with green laser in patients with hyperlipidemia was investigated. The blood of patients was chosen as sample for analysis. The patients were divided in two groups: patients with atherosclerosis of various localization and patients with atherosclerosis associated with diabetes mellitus. The effectiveness of laser impact was evaluated according the blood biochemical indicators. The levels of crude cholesterol, triglycerides, low and very low density lipoproteins, apoproteins A and B, highly sensitive C-reactive protein, atherogenity indicator, glucose content, uric acid content were determined befor and after 1, 3 and 6 months after impact. The study results indicate the occurrence of hypolipedemic and hypoglycemic effects.
Assuntos
Aterosclerose/radioterapia , Diabetes Mellitus/radioterapia , Hiperlipidemias/radioterapia , Terapia a Laser/métodos , Lipoproteínas/efeitos da radiação , Adulto , Idoso , Idoso de 80 Anos ou mais , Aterosclerose/sangue , Glicemia/efeitos da radiação , Proteína C-Reativa/análise , Proteína C-Reativa/efeitos da radiação , Colesterol/sangue , Colesterol/efeitos da radiação , Diabetes Mellitus/sangue , Feminino , Humanos , Hiperlipidemias/sangue , Lasers , Lipoproteínas/sangue , Masculino , Pessoa de Meia-Idade , Triglicerídeos/sangue , Triglicerídeos/efeitos da radiaçãoRESUMO
No disponible
Assuntos
Adulto , Feminino , Humanos , Tamoxifeno/toxicidade , Tamoxifeno/administração & dosagem , Excisão de Linfonodo/métodos , Hormônios/uso terapêutico , Hiperlipidemias/induzido quimicamente , Hiperlipidemias/terapia , Neoplasias da Mama/complicações , Neoplasias da Mama/diagnóstico , Hiperlipidemias/tratamento farmacológico , Hiperlipidemias/radioterapiaRESUMO
On 92 patients the effect of the UV irradiation of blood on the blood parameters is studied. In the blood picture a decrease of leucocytes and reticulocytes is observed, in which case the latter is in connection with the decrease of blood and not with the UVA irradiation. In test persons with increased cholesterol level after UVA therapy as well as after a mere citrate infusion (anticoagulancy) during four weeks highly significant decrease of the cholesterol level, above all of the LDL-cholesterol appears. HDL cholesterol and triglycerides are not influenced. The decrease of cholesterol by citrate infusion is discussed and it is referred to possible therapeutic consequences.