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1.
J Glob Health ; 14: 04072, 2024 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-38700432

RESUMO

Background: Short birth interval is associated with an increased risk of adverse health outcomes for mothers and children. Despite this, there is a lack of comprehensive evidence on short birth interval in the Asia-Pacific region. Thus, this study aimed to synthesise evidence related to the definition, classification, prevalence, and predictors of short birth interval in the Asia-Pacific region. Methods: Five databases (MEDLINE, Scopus, Cumulative Index to Nursing and Allied Health Literature, Maternity and Infant Care, and Web of Science) were searched for studies published between September 2000 and May 2023 (the last search was conducted for all databases in May 2023). We included original studies published in English that reported on short birth interval in the Asia-Pacific region. Studies that combined birth interval with birth order, used multi-country data and were published as conference abstracts and commentaries were excluded. Three independent reviewers screened the articles for relevancy, and two reviewers performed the data extraction and quality assessment. The risk of bias was assessed using the Joanna Briggs Institute critical appraisal tool. The findings were both qualitatively and quantitatively synthesised and presented. Results: A total of 140 studies met the inclusion criteria for this review. About 58% (n = 82) of the studies defined short birth interval, while 42% (n = 58) did not. Out of 82 studies, nearly half (n = 39) measured a birth-to-birth interval, 37 studies measured a birth-to-pregnancy, four measured a pregnancy-to-pregnancy, and two studies measured a pregnancy loss-to-conception. Approximately 39% (n = 55) and 6% (n = 8) of studies classified short birth intervals as <24 months and <33 months, respectively. Most of the included studies were cross-sectional, and about two-thirds had either medium or high risk of bias. The pooled prevalence of short birth interval was 33.8% (95% confidence interval (CI) = 23.0-44.6, I2 = 99.9%, P < 0.01) among the studies that used the World Health Organization definition. Conclusions: This review's findings highlighted significant variations in the definition, measurement, classification, and reported prevalence of short birth interval across the included studies. Future research is needed to harmonise the definition and classification of short birth interval to ensure consistency and comparability across studies and facilitate the development of targeted interventions and policies. Registration: PROSPERO CRD42023426975.


Assuntos
Intervalo entre Nascimentos , Humanos , Ásia/epidemiologia , Feminino , Intervalo entre Nascimentos/estatística & dados numéricos , Gravidez , Recém-Nascido , Ilhas do Pacífico/epidemiologia
2.
J Water Health ; 22(3): 467-486, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38557565

RESUMO

Pacific Island Countries (PICs) collectively have the lowest rates of access to safely managed or basic drinking water and sanitation globally. They are also the least urbanised, have dynamic socioeconomic and increasing climate-linked challenges. Community-based water managers need to respond to variability in water availability and quality caused by a range of hazards. Water Safety Planning (WSP), a widely adopted approach to assessing water supply, offers a risk-based approach to mitigating both existing and future hazards. WSP is adaptable, and making modifications to prescribed WSP to adapt it to the local context is common practice. Within the Pacific Community Water Management Plus research project, we used formative research and co-development processes to understand existing local modifications, whether further modifications are required, and, to develop additional modifications to WSP in Fiji, Vanuatu and Solomon Islands. The types of additional local modifications we recommend reflect the unique context of PICs, including adjusting for community management of water supplies and required collective action, community governance systems, levels of social cohesion in communities, and preferred adult-learning pedagogies. Incorporating modifications that address these factors into future WSP will improve the likelihood of sustained and safe community water services in Pacific and similar contexts.


Assuntos
População Rural , Humanos , Adulto , Ilhas do Pacífico , Vanuatu , Fiji , Melanesia
3.
Artigo em Inglês | MEDLINE | ID: mdl-38673359

RESUMO

Acculturation/enculturation has been found to impact childhood health and obesity status. The objective of this study is to use cross-sectional data to examine the association between proxies of adult/caregiver acculturation/enculturation and child health status (Body Mass Index [BMI], waist circumference [WC], and acanthosis nigricans [AN]) in the U.S.-Affiliated Pacific Islands (USAPI), Alaska, and Hawai'i. Study participants were from the Children's Healthy Living (CHL) Program, an environmental intervention trial and obesity prevalence survey. Anthropometric data from 2-8 year olds and parent/caregiver questionnaires were used in this analysis. The results of this study (n = 4121) saw that those parents/caregivers who identified as traditional had children who were protected against overweight/obesity (OWOB) status and WC > 75th percentile (compared to the integrated culture identity) when adjusted for significant variables from the descriptive analysis. AN did not have a significant association with cultural classification. Future interventions in the USAPI, Alaska, and Hawai'i may want to focus efforts on parents/caregivers who associated with an integrated cultural group as an opportunity to improve health and reduce child OWOB prevalence.


Assuntos
Aculturação , Nível de Saúde , Humanos , Criança , Feminino , Masculino , Estudos Transversais , Pré-Escolar , Havaí/epidemiologia , Saúde da Criança , Adulto , Índice de Massa Corporal , Ilhas do Pacífico/epidemiologia , Obesidade Infantil/epidemiologia , Obesidade Infantil/etnologia
4.
Artigo em Inglês | MEDLINE | ID: mdl-38673419

RESUMO

The Depression, Anxiety, and Stress Scale-21 (DASS-21) has been used in various countries to assess the mental states of individuals. The objectives of this study were to validate the DASS-21 for use in Guam, an island that endures a high burden of mental health challenges, such as suicide, and examine the predictive impact of selected health indicators on DASS-21 variables. Three years of data (2017-2019) were pooled from the Pacific Islands Cohort of College Students (PICCS) study conducted annually at the University of Guam. In total, 726 students were included in the secondary data analysis. MPlus statistical software was used to perform a confirmatory factor analysis (CFA) for the validation and structural equation modeling (SEM) for the predictive modeling. The results from the CFA suggested an acceptable model fit (RMSEA: 0.073, CFI: 0.901, TLI: 0.889, RMR: 0.044), while SEM suggested that sleep quality and physical activity were significant predictors of DASS-21 variables. Therefore, the DASS-21 is a valid instrument for measuring depression, anxiety, and stress among emerging adults in Guam.


Assuntos
Ansiedade , Depressão , Estresse Psicológico , Estudantes , Humanos , Estudantes/psicologia , Estudantes/estatística & dados numéricos , Ansiedade/epidemiologia , Depressão/epidemiologia , Depressão/psicologia , Masculino , Universidades , Feminino , Adulto Jovem , Estudos de Coortes , Adolescente , Adulto , Guam , Ilhas do Pacífico
5.
Gut Liver ; 18(3): 539-549, 2024 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-38638100

RESUMO

Background/Aims: : This study aimed to analyze the trends in mortality attributed to hepatitis B and C around the Western Pacific region from 1990 to 2019. Methods: : We used data from the Global Burden of Disease Study for a systematic analysis. The deaths related to hepatitis B and C were analyzed by age, sex, year, risk factors, geographical location, and Socio-demographic Index (SDI). Results: : From 1990 to 2019, the annual total deaths from hepatitis B decreased from 0.266 to 0.210 million and those from hepatitis C increased from 0.119 to 0.142 million in the Western Pacific region. The age-standardized mortality rate (ASMR) of hepatitis B and C decreased by 63.5% and 48.0%, respectively. The declines in the ASMR related to hepatitis B and C were only detected in 12 and two Western Pacific countries, respectively. As the major risk factors, the contribution of alcohol use to hepatitis B deaths was 52% and drug use to hepatitis C was 80%. In males and females, the ASMR attributed to hepatitis B decreased by 61% and 71%, respectively, and the ASMR attributed to hepatitis C decreased by 43% and 55%, respectively. The association between SDI and ASMRs suggested that hepatitis B and C, respectively, showed an overall decline and stable trends as the SDI improved in the Western Pacific region. Conclusions: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.


Assuntos
Hepatite B , Hepatite C , Humanos , Feminino , Masculino , Hepatite B/mortalidade , Hepatite C/mortalidade , Hepatite C/epidemiologia , Pessoa de Meia-Idade , Fatores de Risco , Adulto , Idoso , Adolescente , Adulto Jovem , Carga Global da Doença/tendências , Mortalidade/tendências , Criança , Pré-Escolar , Ilhas do Pacífico/epidemiologia , Lactente
6.
BMC Health Serv Res ; 24(1): 324, 2024 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-38468255

RESUMO

BACKGROUND: Pacific Island Countries and Territories (PICTs) are known to have high prevalence of Diabetes Mellitus and high incidence of diabetes-related foot disease. Diabetes-related foot disease can lead to lower limb amputation and is associated with poor outcomes, with increased morbidity and mortality. The purpose of this study was to gain a better understanding of diabetes-related foot disease management in selected countries in PICTs and to identify potential barriers in management of diabetes-related foot disease management in the region. METHODS: A cross-sectional survey was sent to eleven hospitals across six selected PICTs. The survey instrument was designed to provide an overview of diabetes-related foot disease (number of admissions, and number of lower limb amputations over 12 months) and to identify clinical services available within each institution. Two open-ended questions (free text responses) were included in the instrument to explore initiatives that have helped to improve management and treatment of diabetes-related foot diseases, as well as obstacles that clinicians have encountered in management of diabetes-related foot disease. The survey was conducted over 6 weeks. RESULTS: Seven hospitals across four countries provided responses. Number of admissions and amputations related to diabetes-related foot disease were only reported as an estimate by clinicians. Diabetes-related foot disease was managed primarily by general medicine physician, general surgeon and/or orthopaedic surgeon in the hospitals surveyed, as there were no subspecialty services in the region. Only one hospital had access to outpatient podiatry. Common themes identified around barriers faced in management of diabetes-related foot disease by clinicians were broadly centred around resource availability, awareness and education, and professional development. CONCLUSION: Despite the high prevalence of diabetes-related foot disease within PICTs, there appears to be a lack of functional multi-disciplinary foot services (MDFs). To improve the outcomes for diabetes-related foot disease patients in the region, there is a need to establish functional MDFs and engage international stakeholders to provide ongoing supports in the form of education, mentoring, as well as physical resources.


Assuntos
Diabetes Mellitus , Pé Diabético , Doenças do Pé , Humanos , Estudos Transversais , Diabetes Mellitus/epidemiologia , Diabetes Mellitus/terapia , Pé Diabético/terapia , Pé Diabético/cirurgia , Gerenciamento Clínico , Extremidade Inferior , Ilhas do Pacífico/epidemiologia
8.
Sci Total Environ ; 922: 170973, 2024 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-38365026

RESUMO

Assessing how forests respond to, and recuperate from, cyclones is critical to understanding forest dynamics and planning for the impacts of climate change. Projected increases in the intensity and frequency of severe cyclones can threaten both forests and forest-dependent communities. The Pacific Islands are subject to frequent low-intensity cyclones, but there is little information on the effects of high intensity cyclones, or on how forest stewardship practices may affect outcomes. We assess the resistance and resilience of forests in three community-stewarded sites on the island of Tanna, Vanuatu, to the wind-related effects of 2015 Category-5 Cyclone Pam, one of the most intense cyclones to make landfall globally. Drawing on transect data established pre-and post-cyclone, we (1) test whether windspeed and tree structural traits predict survival and damage intensity, and whether this varies across sites; (2) assess post-cyclone regeneration of canopy, ground cover, seedlings, and saplings, and how community composition shifts over time and across sites. In sites that sustained a direct hit, 88 % of trees were defoliated, 34 % sustained severe damage, and immediate mortality was 13 %. Initial mortality, but not severe damage, was lower in areas that received an indirect hit and had lower windspeed. Larger trees and those with lighter wood had a higher probability of uprooting and snapping, respectively. Canopy and ground cover regenerated within three years and seedling and sapling regeneration was widespread across life histories, from pioneer to mature forest species. Three species of non-native vines recruited post-cyclone but within 5 years had largely declined or disappeared with canopy closure. Tanna's historical cyclone frequency, combined with customary stewardship practices that actively maintain a diversity of species and multiplicity of regeneration pathways, are likely responsible for the island's resistance and resilience to an intense tropical cyclone.


Assuntos
Tempestades Ciclônicas , Resiliência Psicológica , Ilhas do Pacífico , Florestas , Madeira , Plântula , Ecossistema
9.
Hawaii J Health Soc Welf ; 83(2): 48-53, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38344695

RESUMO

The objective of this study was to estimate the prevalence of chronic hepatitis B infection in foreign-born Asians and Pacific Islanders at Kalihi-Palama Health Center in Honolulu, Hawai'i, and to assess the association between both chronic and resolved hepatitis B infection and risk factors such as household exposure to hepatitis B virus and geographic location of birthplace. The study involved cross-sectional data from 997 participants who accessed medical services at Kalihi-Palama Health Center between September 2015 and July 2020. The prevalence of chronic hepatitis B was 10.7%. On multivariable logistic regression analysis, the adjusted prevalence odds ratio of chronic hepatitis B infection was 3.3 times greater (95% confidence interval: 1.1, 9.2) for those who reported household contact with a person with hepatitis B infection than those who reported no such contact. No association was found with place of birth in this study population. Age was a significant predictor of chronic hepatitis B, with participants between 35-44 years of age having the highest prevalence. Age was also a significant predictor of resolved hepatitis B infection, with participants 65 years of age or older having the highest prevalence. These findings emphasize the need for targeted screening and appropriate follow-up-including vaccination or treatment-in this at-risk population.


Assuntos
Asiático , Emigrantes e Imigrantes , Hepatite B Crônica , População das Ilhas do Pacífico , Adulto , Humanos , Ásia/etnologia , Asiático/estatística & dados numéricos , Estudos Transversais , Havaí/epidemiologia , Hepatite B/epidemiologia , Hepatite B Crônica/epidemiologia , Hepatite B Crônica/prevenção & controle , População das Ilhas do Pacífico/estatística & dados numéricos , Ilhas do Pacífico/etnologia , Prevalência , Fatores de Risco , Idoso , Emigrantes e Imigrantes/estatística & dados numéricos
10.
Science ; 383(6682): 472-477, 2024 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-38301000

RESUMO

On a remote Pacific island, clues to El Niño's future are preserved in ancient reefs.


Assuntos
Antozoários , Recifes de Corais , Animais , El Niño Oscilação Sul , Ilhas do Pacífico
11.
Rev Med Virol ; 34(2): e2521, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38340071

RESUMO

Dengue, Zika and chikungunya outbreaks pose a significant public health risk to Pacific Island communities. Differential diagnosis is challenging due to overlapping clinical features and limited availability of laboratory diagnostic facilities. There is also insufficient information regarding the complications of these arboviruses, particularly for Zika and chikungunya. We conducted a systematic review and meta-analysis to calculate pooled prevalence estimates with 95% confidence intervals (CI) for the clinical manifestations of dengue, Zika and chikungunya in the Pacific Islands. Based on pooled prevalence estimates, clinical features that may help to differentiate between the arboviruses include headache, haemorrhage and hepatomegaly in dengue; rash, conjunctivitis and peripheral oedema in Zika; and the combination of fever and arthralgia in chikungunya infections. We estimated that the hospitalisation and mortality rates in dengue were 9.90% (95% CI 7.67-12.37) and 0.23% (95% CI 0.16-0.31), respectively. Severe forms of dengue occurred in 1.92% (95% CI 0.72-3.63) of reported cases and 23.23% (95% CI 13.58-34.53) of hospitalised patients. Complications associated with Zika virus included Guillain-Barré syndrome (GBS), estimated to occur in 14.08 (95% CI 11.71-16.66) per 10,000 reported cases, and congenital brain malformations such as microcephaly, particularly with first trimester maternal infection. For chikungunya, the hospitalisation rate was 2.57% (95% CI 1.30-4.25) and the risk of GBS was estimated at 1.70 (95% CI 1.06-2.48) per 10,000 reported cases. Whilst ongoing research is required, this systematic review enhances existing knowledge on the clinical manifestations of dengue, Zika and chikungunya infections and will assist Pacific Island clinicians during future arbovirus outbreaks.


Assuntos
Arbovírus , Febre de Chikungunya , Dengue , Infecção por Zika virus , Zika virus , Humanos , Febre de Chikungunya/complicações , Febre de Chikungunya/diagnóstico , Febre de Chikungunya/epidemiologia , Ilhas do Pacífico/epidemiologia , Dengue/complicações , Dengue/diagnóstico , Dengue/epidemiologia , Infecção por Zika virus/complicações , Infecção por Zika virus/diagnóstico , Infecção por Zika virus/epidemiologia
12.
Nat Ecol Evol ; 8(3): 511-518, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38225430

RESUMO

The increasing similarity of plant species composition among distinct areas is leading to the homogenization of ecosystems globally. Human actions such as ecosystem modification, the introduction of non-native plant species and the extinction or extirpation of endemic and native plant species are considered the main drivers of this trend. However, little is known about when floristic homogenization began or about pre-human patterns of floristic similarity. Here we investigate vegetation trends during the past 5,000 years across the tropical, sub-tropical and warm temperate South Pacific using fossil pollen records from 15 sites on 13 islands within the biogeographical realm of Oceania. The site comparisons show that floristic homogenization has increased over the past 5,000 years. Pairwise Bray-Curtis similarity results also show that when two islands were settled by people in a given time interval, their floristic similarity is greater than when one or neither of the islands were settled. Importantly, higher elevation sites, which are less likely to have experienced human impacts, tended to show less floristic homogenization. While biotic homogenization is often referred to as a contemporary issue, we have identified a much earlier trend, likely driven by human colonization of the islands and subsequent impacts.


Assuntos
Biodiversidade , Ecossistema , Humanos , Ilhas do Pacífico , Plantas , Pólen
14.
Environ Monit Assess ; 196(2): 120, 2024 Jan 09.
Artigo em Inglês | MEDLINE | ID: mdl-38191753

RESUMO

Small island countries like Vanuatu are facing the brunt of climate change, sea level rise (SLR), tropical cyclones, and limited or declining access to freshwater. The Tagabe coastal aquifer in Port Vila (the capital of Vanuatu) shows the presence of salinity, indicating saltwater intrusion (SWI). This study aims to develop and evaluate effective SWI management strategies for Tagabe coastal aquifer. To manage SWI, the numerical simulation model for the study area was developed using the SEAWAT code. The flow model was developed using MODFLOW and the transport model was developed using MT3DMS. Whereby SEAWAT solved flow and transport equations simultaneously. The model was calibrated, and different scenarios were evaluated for the management of SWI. The SLR was also considered in the model simulations. The results indicated that increased population, pumping rates, and SLR affect the SWI rates. To manage the SWI, we introduced hydraulic barriers like barrier wells and injection wells which effectively managed SWI in Tagabe coastal aquifer. The results from this study are significantly important whereby, the water managers, site owners, and governing bodies can use the management strategies presented in this study to create policies and regulations for managing SWI rates in Port Vila. Additionally, the water industry, private businesses, and investors who wish to extract groundwater from the Tagabe can use this study as a reference for daily or yearly freshwater production rates without the risk of SWI.


Assuntos
Mudança Climática , Monitoramento Ambiental , Vanuatu , Ilhas do Pacífico , Água
16.
Manille; Bureau régional de l'OMS pour le Pacifique occidental; 2024. (WPR/2024/DPS/001).
em Francês | WHO IRIS | ID: who-376225

RESUMO

La quinzième Réunion des ministres de la Santé du Pacifique a rassemblé, du 20 au 22 septembre 2023, les responsables de la santé de l’ensemble du Pacifique sous les auspices du gouvernement du Royaume des Tonga et avec le concours de l’Organisation mondiale de la Santé (OMS) et de la Communauté du Pacifique (CPS).


Les débats se sont concentrés sur quatre principaux points de l’ordre du jour : 1) repenser les ressources humaines pour la santé ; 2) s’attaquer aux facteurs d’obésité, en particulier chez les enfants et les jeunes ; 3) faire progresser l’information sanitaire et la transformation numérique dans le secteur de la santé ; et 4) renforcer la résilience des systèmes de santé.


Le présent document expose les engagements pris par les ministres ayant participé à la réunion.


Assuntos
Programas Gente Saudável , Ilhas do Pacífico
18.
Manila; WHO Regional Office for the Western Pacific; 2024. (WPR/2024/DPS/001).
em Inglês | WHO IRIS | ID: who-375620

RESUMO

The Fifteenth Pacific Health Ministers Meeting brought together health leaders from across the Pacific, hosted by the Government of the Kingdom of Tonga with support from the World Health Organization (WHO) and the Pacific Community (SPC) from 20-22 September 2023.


The event focused on four main agenda items: (1) rethinking human resources for health; (2)tackling the drivers of obesity, particularly for children and young people; (3) advancing health information and digital transformation in the health sector; and, (4) strengthening health system resilience.


This document outlines the commitments made by the ministers who attended the event.


Assuntos
Programas Gente Saudável , Ilhas do Pacífico
19.
Public Health Nutr ; 27(1): e20, 2023 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-38126269

RESUMO

OBJECTIVE: To systematically identify and review food taxation policy changes in Pacific Island Countries and Territories (PICTs). DESIGN: Food taxation polices, regarding excise taxes and tariffs applied from 2000 to 2020 in twenty-two PICTs, and their key characteristics were reviewed. The search was conducted using databases, government legal repositories and broad-based search engines. Identified documents for screening included legislation, reports, academic literature, news articles and grey literature. Key informants were contacted from each PICT to retrieve further data and confirm results. Results were analysed by narrative synthesis. SETTING: Noncommunicable diseases (NCD) are the leading cause of premature death in PICTs and in many jurisdictions globally. An NCD crisis has been declared in the Pacific, and food taxation policy has been recommended to address the dietary risk factors associated with. Progress is unclear. RESULTS: Of the twenty-two PICTs included in the study, fourteen had food taxation policies and five introduced excise taxes. Processed foods, sugar and salt were the main target of excise taxes. A total of eighty-four food taxation policy changes were identified across all food groups. There was a total of 279 taxes identified by food group, of which 85 % were tariffs and 15 % were excise taxes. Individual tax rates varied substantially. The predominant tax design was ad valorem, and this was followed by volumetric. CONCLUSIONS: A quarter of PICTs have introduced food excise taxes from 2000 to 2020. Further excise taxes, specifically tiered or nutrient-specific designs, could be introduced and more systematically applied to a broader range of unhealthy foods.


Assuntos
Doenças não Transmissíveis , Humanos , Alimentos , Política Nutricional , Ilhas do Pacífico , Impostos
20.
PLoS One ; 18(12): e0293681, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38127863

RESUMO

AIMS: To assess the burden of type 2 diabetes in Pacific Island countries and predict future trends. METHODS: We analyzed and processed data using R and Excel software, performed Joinpoint 4.7.0 software analysis to investigate changing trends in disease burden, and used an autoregressive integrated moving average model to forecast future trends. RESULTS: Our study showed that from 1990 to 2019, the burden of type 2 diabetes in Pacific Island countries continues to increase, with the standardized incidence rate showing the most significant growth. Moreover, there were significant differences in the burden of type 2 diabetes between regions. In 2019, American Samoa had the highest standardized incidence rate, while Fiji had the highest standardized death rate and disability-adjusted life year rate. The standardized incidence rate peaked at ages 65-69 years, while the standardized death rate and disability-adjusted life year rate peaked at ages 95 years and 70-74 years respectively. Type 2 diabetes burden was higher among males than females. Based on our forecasting, from 2020 to 2030, the standardized incidence rate is expected to continue to rise, while the standardized death rate and disability-adjusted life year rate will slowly decline. CONCLUSIONS: Our study highlights that the burden of type 2 diabetes in Pacific Island countries has been increasing from 1990 to 2019. Therefore, it is imperative to strengthen disease prevention and control measures in the region.


Assuntos
Diabetes Mellitus Tipo 2 , Feminino , Masculino , Humanos , Diabetes Mellitus Tipo 2/epidemiologia , Ilhas do Pacífico/epidemiologia , Samoa Americana , Efeitos Psicossociais da Doença , Anos de Vida Ajustados por Deficiência , Carga Global da Doença , Anos de Vida Ajustados por Qualidade de Vida , Incidência
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