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1.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 46(2): 210-216, 2024 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-38686717

RESUMO

Objective To construct a scientific and practical management model of the hospice and palliative care outpatient clinic and provide a reference for the operation and development of the outpatient clinic. Methods The basic framework of the whole process management model of hospice and palliative care outpatient clinic was determined preliminarily by literature analysis,qualitative interviews and experts group meetings.Two rounds of consultation were conducted among 18 experts in hospice and palliative care and medical-nursing combined outpatient service by the Delphi method. Results The questionnaire response rates of the two rounds of expert consultation were both 100% and the authority coefficients of the two rounds of expert consultation were 0.88 and 0.91,respectively.Finally,the whole process management model of hospice and palliative care outpatient clinic was constructed,which was composed of three first-level indicators including staff composition,work structure and effect evaluation,5 second-level indicators and 62 third-level indicators. Conclusion The constructed whole process management model is scientific,innovative and continuous,which can provide a reference for the operation and development of the hospice and palliative care outpatient clinic.


Assuntos
Instituições de Assistência Ambulatorial , Cuidados Paliativos na Terminalidade da Vida , Cuidados Paliativos , Cuidados Paliativos na Terminalidade da Vida/organização & administração , Instituições de Assistência Ambulatorial/organização & administração , Inquéritos e Questionários , Humanos
2.
Semin Oncol Nurs ; 40(2): 151585, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38423821

RESUMO

OBJECTIVE: This quality improvement project was a collaborative effort with Penn Medicine's emergency department (ED) and oncology nurse navigators (ONNs). The goal of the project was to streamline patient transitions from the ED to the outpatient oncology clinic by developing a standardized referral process. The main objectives were to simplify and automate the referral process using the electronic medical record, improve multidisciplinary communication across the care continuum, ensure timely follow-up, and address barriers to oncology care. METHODS: The ED providers placed a consult to ONNs. The ONNs reached out to the patient within 48 hours of the consult. They maintained a database of patient referrals and collected information such as patient demographics, reason for referral, insurance, and patient outcomes. RESULTS: The ED providers referred 204 patients to the ONNs from April 2022 to September 2023. The development of a standardized referral process from the ED to the outpatient oncology clinic proved successful. Of the patients referred, the ONNs facilitated 98 cancer diagnoses and 80 of those patients are receiving oncology care at Penn Medicine. The median time to the patient's first appointments was seven days, diagnosis was 15 days, and treatment initiation occurred within 32 days. CONCLUSION: The project team achieved their goal of facilitating timely access to oncology care, ensuring continuity, and addressing patient-specific barriers. IMPLICATIONS FOR NURSING PRACTICE: This quality improvement initiative highlights the ONNs' role in enhancing access and equity in cancer care delivery. The success of the project underscores the ONN's expertise and leadership in addressing healthcare disparities in oncology care. Collaboratively, the teams created a new referral workflow improving care transitions from the ED to the outpatient oncology clinic. The project sets a precedent for optimizing patient care transitions, demonstrating the positive impact of ONNs as key members of the multidisciplinary healthcare team.


Assuntos
Instituições de Assistência Ambulatorial , Continuidade da Assistência ao Paciente , Serviço Hospitalar de Emergência , Neoplasias , Enfermagem Oncológica , Melhoria de Qualidade , Humanos , Serviço Hospitalar de Emergência/organização & administração , Feminino , Masculino , Enfermagem Oncológica/organização & administração , Enfermagem Oncológica/normas , Melhoria de Qualidade/organização & administração , Continuidade da Assistência ao Paciente/organização & administração , Neoplasias/terapia , Neoplasias/enfermagem , Instituições de Assistência Ambulatorial/organização & administração , Pessoa de Meia-Idade , Encaminhamento e Consulta/organização & administração , Adulto , Transferência de Pacientes/organização & administração , Transferência de Pacientes/normas , Idoso , Navegação de Pacientes/organização & administração
3.
J Gen Intern Med ; 39(5): 873-877, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38286972

RESUMO

BACKGROUND: While student-run free clinics (SRFCs) play an important role in care for underserved populations, few mechanisms exist to promote collaboration among regional SRFCs. AIMS: To address this gap, the Chicagoland Free Clinics Consortium (CFCC) was formed to (1) facilitate collaboration between Chicagoland SRFCs, (2) provide innovation grant funding, and (3) host an annual conference. SETTING AND PARTICIPANTS: In 2018, students from the Pritzker School of Medicine founded the CFCC and partnered with peers from area schools to implement programming. PROGRAM DESCRIPTION: Between 2018 and 2022, CFCC engaged 23 SRFCs representing all 6 Chicagoland schools, held 4 annual conferences, and distributed $15,423 in grants to 19 projects at 14 SRFC sites. PROGRAM EVALUATION: A total of 176 students from 5 schools attended the 4 conferences. In 2022, 82 unique participants were surveyed, and 66% (54/82) responded. Eighty percent (43/54) reported they were "more likely to collaborate with other Chicagoland free clinics." In 2022, all grant sites were surveyed and 84% (16/19) responded. Most (87%,14/16) agreed the grant "allowed them to implement a project that would not have otherwise been accomplished" and 21% (4/19) were inter-institutional collaborations. DISCUSSION: To our knowledge, CFCC is the first student-led organization to promote sustained collaboration across SRFCs in a metropolitan area.


Assuntos
Clínica Dirigida por Estudantes , Humanos , Clínica Dirigida por Estudantes/organização & administração , Avaliação de Programas e Projetos de Saúde , Comportamento Cooperativo , Área Carente de Assistência Médica , Estudantes de Medicina , Instituições de Assistência Ambulatorial/organização & administração
4.
JAMA Netw Open ; 6(8): e2328627, 2023 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-37566414

RESUMO

Importance: Medication for opioid use disorder (MOUD) (eg, buprenorphine and naltrexone) can be offered in primary care, but barriers to implementation exist. Objective: To evaluate an implementation intervention over 2 years to explore experiences and perspectives of multidisciplinary primary care (PC) teams initiating or expanding MOUD. Design, Setting, and Participants: This survey-based and ethnographic qualitative study was conducted at 12 geographically and structurally diverse primary care clinics that enrolled in a hybrid effectiveness-implementation study from July 2020 to July 2022 and included PC teams (prescribing clinicians, nonprescribing behavioral health care managers, and consulting psychiatrists). Survey data analysis was conducted from February to April 2022. Exposure: Implementation intervention (external practice facilitation) to integrate OUD treatment alongside existing collaborative care for mental health services. Measures: Data included (1) quantitative surveys of primary care teams that were analyzed descriptively and triangulated with qualitative results and (2) qualitative field notes from ethnographic observation of clinic implementation meetings analyzed using rapid assessment methods. Results: Sixty-two primary care team members completed the survey (41 female individuals [66%]; 1 [2%] American Indian or Alaskan Native, 4 [7%] Asian, 5 [8%] Black or African American, 5 [8%] Hispanic or Latino, 1 [2%] Native Hawaiian or Other Pacific Islander, and 46 [4%] White individuals), of whom 37 (60%) were between age 25 and 44 years. An analysis of implementation meetings (n = 362) and survey data identified 4 themes describing multilevel factors associated with PC team provision of MOUD during implementation, with variation in their experience across clinics. Themes characterized challenges with clinical administrative logistics that limited the capacity to provide rapid access to care and patient engagement as well as clinician confidence to discuss aspects of MOUD care with patients. These challenges were associated with conflicting attitudes among PC teams toward expanding MOUD care. Conclusions and Relevance: The results of this survey and qualitative study of PC team perspectives suggest that PC teams need flexibility in appointment scheduling and the capacity to effectively engage patients with OUD as well as ongoing training to maintain clinician confidence in the face of evolving opioid-related clinical issues. Future work should address structural challenges associated with workload burden and limited schedule flexibility that hinder MOUD expansion in PC settings.


Assuntos
Transtornos Relacionados ao Uso de Opioides , Atenção Primária à Saúde , Adulto , Feminino , Humanos , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Indígena Americano ou Nativo do Alasca/estatística & dados numéricos , Analgésicos Opioides/uso terapêutico , Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico , Transtornos Relacionados ao Uso de Opioides/epidemiologia , Transtornos Relacionados ao Uso de Opioides/etnologia , Atenção Primária à Saúde/métodos , Atenção Primária à Saúde/organização & administração , Atenção Primária à Saúde/estatística & dados numéricos , Masculino , Equipe de Assistência ao Paciente/estatística & dados numéricos , Asiático/estatística & dados numéricos , Negro ou Afro-Americano/estatística & dados numéricos , Hispânico ou Latino/estatística & dados numéricos , Havaiano Nativo ou Outro Ilhéu do Pacífico/estatística & dados numéricos , Brancos/estatística & dados numéricos , Agendamento de Consultas , Carga de Trabalho
5.
J Nurs Adm ; 53(6): 313-318, 2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-37184482

RESUMO

Ambulatory staffing to workload based on visit volume in an outpatient setting is an elusive formula, and the literature describing such processes is limited. One health system tasked a multidisciplinary team with developing an ambulatory staffing to workload tool to meet the needs of staff, management, and leadership. The resultant tool includes an automated dashboard for determining staffing needs on the basis of quantified workload, prospective modeling, and historical dashboards to demonstrate actual staffing (full-time equivalents) to workload (outpatient volumes) compared with budget.


Assuntos
Instituições de Assistência Ambulatorial , Liderança , Admissão e Escalonamento de Pessoal , Carga de Trabalho , Humanos , Recursos Humanos , Instituições de Assistência Ambulatorial/organização & administração , Equipe de Assistência ao Paciente
6.
São Paulo; s.n; 2023. 25 p.
Tese em Português | Coleciona SUS, Sec. Munic. Saúde SP, HSPM-Producao, Sec. Munic. Saúde SP | ID: biblio-1531178

RESUMO

Introdução: A Displasia do Desenvolvimento do Quadril (DDQ) é uma doença caracterizada pela alteração anatômica durante a diferenciação embriológica do quadril ou durante o crescimento e desenvolvimento deste. O diagnóstico precoce tem grande importância na DDQ, pois logo que detectada qualquer anormalidade no quadril pediátrico, é possível uma intervenção precoce, a fim de realizar um tratamento não invasivo e de baixo custo. Ainda não existe um protocolo estabelecido de rastreio com ultrassonografia (USG) para a DDQ no Brasil. Objetivo: Implementar uma sistemática de rastreio universal para displasia do desenvolvimento dos quadris em um hospital público na cidade de São Paulo. Método: Foi realizada uma revisão da literatura a fim de justificar a importância da criação e estruturação de um Ambulatório Especializado em DDQ no Hospital do Servidor Público Municipal. Essa revisão buscou demonstrar os benefícios de um diagnóstico precoce. A partir disso, montou-se a estruturação do ambulatório. Serão acompanhados no ambulatório todos os recém-nascidos dependentes de servidores públicos municipais de São Paulo, de acordo com o protocolo estabelecido pela Instituição. Resultados: Foi proposto um modelo de atendimento envolvendo: exame físico e exames complementares, diagnóstico, tratamento conservador e/ou cirúrgico e seguimento dos pacientes. Conclusão: O atendimento do paciente portador de DDQ será centralizado. Isso inclui as etapas de diagnóstico, avaliação da evolução nos diferentes estágios do acompanhamento, tratamento com órteses específicas ou realização de cirurgias complementares. Toda a equipe multidisciplinar será composta por profissionais capacitados e treinados, em um ambiente único, o que evitará encaminhamentos. Palavras-chave: Displasia do desenvolvimento dos quadris. Ambulatório. Diagnóstico.


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Recém-Nascido/crescimento & desenvolvimento , Protocolos Clínicos , Ultrassonografia , Instituições de Assistência Ambulatorial/organização & administração , Displasia do Desenvolvimento do Quadril/diagnóstico , Quadril/anormalidades
7.
JAMA ; 328(5): 451-459, 2022 08 02.
Artigo em Inglês | MEDLINE | ID: mdl-35916847

RESUMO

Importance: Care of adults at profit vs nonprofit dialysis facilities has been associated with lower access to transplant. Whether profit status is associated with transplant access for pediatric patients with end-stage kidney disease is unknown. Objective: To determine whether profit status of dialysis facilities is associated with placement on the kidney transplant waiting list or receipt of kidney transplant among pediatric patients receiving maintenance dialysis. Design, Setting, and Participants: This retrospective cohort study reviewed the US Renal Data System records of 13 333 patients younger than 18 years who started dialysis from 2000 through 2018 in US dialysis facilities (followed up through June 30, 2019). Exposures: Time-updated profit status of dialysis facilities. Main Outcomes and Measures: Cox models, adjusted for clinical and demographic factors, were used to examine time to wait-listing and receipt of kidney transplant by profit status of dialysis facilities. Results: A total of 13 333 pediatric patients who started receiving maintenance dialysis were included in the analysis (median age, 12 years [IQR, 3-15 years]; 6054 females [45%]; 3321 non-Hispanic Black patients [25%]; 3695 Hispanic patients [28%]). During a median follow-up of 0.87 years (IQR, 0.39-1.85 years), the incidence of wait-listing was lower at profit facilities than at nonprofit facilities, 36.2 vs 49.8 per 100 person-years, respectively (absolute risk difference, -13.6 (95% CI, -15.4 to -11.8 per 100 person-years; adjusted hazard ratio [HR] for wait-listing at profit vs nonprofit facilities, 0.79; 95% CI, 0.75-0.83). During a median follow-up of 1.52 years (IQR, 0.75-2.87 years), the incidence of kidney transplant (living or deceased donor) was also lower at profit facilities than at nonprofit facilities, 21.5 vs 31.3 per 100 person-years, respectively; absolute risk difference, -9.8 (95% CI, -10.9 to -8.6 per 100 person-years) adjusted HR for kidney transplant at profit vs nonprofit facilities, 0.71 (95% CI, 0.67-0.74). Conclusions and Relevance: Among a cohort of pediatric patients receiving dialysis in the US from 2000 through 2018, profit facility status was associated with longer time to wait-listing and longer time to kidney transplant.


Assuntos
Instituições de Assistência Ambulatorial , Acessibilidade aos Serviços de Saúde , Falência Renal Crônica , Transplante de Rim , Diálise Renal , Listas de Espera , Adolescente , Instituições de Assistência Ambulatorial/economia , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Criança , Pré-Escolar , Feminino , Administração de Instituições de Saúde/economia , Administração de Instituições de Saúde/estatística & dados numéricos , Acessibilidade aos Serviços de Saúde/economia , Acessibilidade aos Serviços de Saúde/organização & administração , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Humanos , Falência Renal Crônica/economia , Falência Renal Crônica/epidemiologia , Falência Renal Crônica/terapia , Transplante de Rim/economia , Transplante de Rim/estatística & dados numéricos , Masculino , Organizações sem Fins Lucrativos/economia , Organizações sem Fins Lucrativos/organização & administração , Organizações sem Fins Lucrativos/estatística & dados numéricos , Propriedade/economia , Propriedade/estatística & dados numéricos , Diálise Renal/economia , Diálise Renal/estatística & dados numéricos , Estudos Retrospectivos , Fatores de Tempo
9.
Adm Policy Ment Health ; 49(5): 785-797, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35583566

RESUMO

The Leadership and Organizational Change for Implementation (LOCI) strategy is a multifaceted implementation strategy that aims to support successful evidence-based practice (EBP) implementation by fostering effective general leadership, implementation leadership, and implementation climate. How implementation strategies are experienced by participants is important for their utilization and effectiveness in supporting EBP implementation. The current study is the first in-depth qualitative study exploring first-level leaders' experiences of participating in the LOCI strategy. Data were collected as part of a trial where Norwegian child and adult mental health outpatient clinics implemented EBPs for posttraumatic stress disorder (PTSD). Eleven first-level leaders from adult and child clinics participated in semi-structured interviews after completing the LOCI strategy. Data were analyzed through reflexive thematic analysis. The analysis generated four themes related to leaders' experiences of participating in the LOCI strategy: (1) structuring the EBP implementation, (2) taking responsibility for the EBP implementation, (3) interacting with others about the EBP implementation, and (4) becoming aware of EBP implementation and their own leadership. Most participants experienced the LOCI strategy as beneficial for implementing EBPs for PTSD in their clinic. The strategy succeeded in raising awareness of leadership for EBP implementation, and simultaneously provided participants with tools and support for leading the implementation in their clinic. Two participants experienced LOCI as less beneficial than the others. Our results support the strategy's potential to engage and empower first-level leaders to get involved in implementation processes and point to important challenges for future research on implementation strategies.


Assuntos
Prática Clínica Baseada em Evidências , Liderança , Inovação Organizacional , Adulto , Instituições de Assistência Ambulatorial/organização & administração , Criança , Prática Clínica Baseada em Evidências/organização & administração , Humanos , Serviços de Saúde Mental/organização & administração , Noruega , Pesquisa Qualitativa , Transtornos de Estresse Pós-Traumáticos/terapia
10.
Clin Epigenetics ; 14(1): 13, 2022 01 21.
Artigo em Inglês | MEDLINE | ID: mdl-35063029

RESUMO

BACKGROUND: Different functional somatic syndromes (FSS), fibromyalgia (FMS) and other unexplained painful conditions share many common clinical traits and are characterized by troubling and functionally disabling somatic symptoms. Chronic pain is most frequently reported and at the center of patients' level of disease burden. The construct of multisomatoform disorder (MSD) allows to subsume severely impaired patients suffering from FSS, FMS and other unexplained painful conditions to be examined for common underlying processes. Altered leptin levels and a pathological response of the HPA-axis as a result of chronic stress and childhood trauma have been suggested as one of the driving factors of disease development and severity. Previous studies have demonstrated that methylation of the leptin promoter can play a regulatory role in addiction. In this study, we hypothesized that methylation of the leptin promoter is influenced by the degree of childhood traumatization and differs between patients with MSD and controls. A cohort of 151 patients with MSD and 149 matched healthy volunteers were evaluated using clinical and psychometric assessment while methylation level analysis of the leptin promoter was performed using DNA isolated from whole blood. RESULTS: In female controls, we found CpG C-167 to be negatively correlated with leptin levels, whereas in female patients CpG C-289, C-255, C-193, C-167 and methylation cluster (C-291 to C-167) at putative bindings sites for transcription factors Sp1 and c/EBPalpha were negatively correlated with leptin levels. Methylation levels were significantly lower in female patients CpG C-289 compared with controls. When looking at female patients with chronic widespread pain methylation levels were significantly lower at CpG C-289, C-255 and methylation cluster (C-291 to C-167). CONCLUSION: Our findings support the hypothesis that epigenetic regulation of leptin plays a role in the regulation of leptin levels in patients with MSD. This effect is more pronounced in patients with chronic widespread pain.


Assuntos
Dor Crônica/genética , Metilação de DNA/genética , Leptina/farmacologia , Transtornos Somatoformes/genética , Adulto , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Dor Crônica/fisiopatologia , Metilação de DNA/fisiologia , Feminino , Alemanha , Humanos , Leptina/análise , Leptina/sangue , Pessoa de Meia-Idade , Regiões Promotoras Genéticas , Transtornos Somatoformes/fisiopatologia
11.
Clin Pediatr (Phila) ; 61(1): 26-33, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34514898

RESUMO

The COVID-19 (coronavirus disease 2019) pandemic brought rapid expansion of pediatric telehealth to maintain patient access to care while decreasing COVID-19 community spread. We designed a retrospective, serial, cross-sectional study to investigate if telehealth implementation at an academic pediatric practice led to disparities in health care access. Significant differences were found in pre-COVID-19 versus during COVID-19 patient demographics. Patients seen during COVID-19 were more likely to be younger, White/Caucasian or Asian, English speaking, and have private insurance. They were less likely to be Black/African American or Latinx and request interpreters. Age was the only significant difference in patient demographics between in-person and telehealth visits during COVID-19. A multivariate regression showed older age as a significant positive predictor of having a video visit and public insurance as a significant negative predictor. Our study demonstrates telehealth disparities based on insurance existed at our clinic as did inequities in who was seen before versus during COVID-19.


Assuntos
Disparidades em Assistência à Saúde/estatística & dados numéricos , Telemedicina/normas , População Urbana/estatística & dados numéricos , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , COVID-19/prevenção & controle , California , Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Lactente , Masculino , Atenção Primária à Saúde/métodos , Atenção Primária à Saúde/normas , Atenção Primária à Saúde/estatística & dados numéricos , Estudos Retrospectivos , Telemedicina/métodos , Telemedicina/estatística & dados numéricos
12.
Acad Med ; 97(2): 233-238, 2022 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-34039853

RESUMO

PROBLEM: Family medicine faculty and residents have observed that continuity clinic is often unsatisfying, attributed to a lack of patient and team continuity and erratic clinic schedules pieced together after the prioritization of hospital service and rotation schedules. APPROACH: In 2019, a 3-year Clinic First project, called Clinic as Curriculum (CaC), was launched across the 4 family medicine residencies of the Department of Family Medicine and Community Health, University of Minnesota Medical School. The department began publishing quarterly CaC dashboard data. Each clinic completed a baseline assessment of their performance on the 13 Building Blocks of High-Performing Primary Care. Using their baseline data, each clinic identified which block or blocks, in addition to the blocks on continuity of care and resident scheduling, to focus on. The plan is to collaboratively implement the overall and local goals using dashboard data and iterative process improvement over 3 years. OUTCOMES: At baseline, clinics functioned quite well with respect to the 13 building blocks, but CaC dashboard data varied across the 4 clinics, with large variation between clinics on how frequently faculty were scheduled in the clinic and the proportion of total clinic visits seen by faculty. Resident continuity rates were low (range, 38%-47%). Level loading (consistent physician availability to meet patient demand) rates ranged from 1 to 11 days a month. Regarding resident schedules, 2 programs are moving from 4-week to 2-week inpatient blocks, and 2 programs are exploring longitudinal scheduling. One clinic will assign faculty and residents to specific clinic days. Two clinics are implementing microteams of 1 faculty and 3-4 residents. NEXT STEPS: The authors plan to analyze the dashboard data longitudinally; explore microteams, team continuity, and team scheduling adherence; and develop and implement resident scheduling changes over the next 3 years.


Assuntos
Instituições de Assistência Ambulatorial/organização & administração , Assistência Ambulatorial/estatística & dados numéricos , Continuidade da Assistência ao Paciente/estatística & dados numéricos , Docentes/estatística & dados numéricos , Medicina de Família e Comunidade/organização & administração , Pacientes Internados/estatística & dados numéricos , Internato e Residência/organização & administração , Assistência Ambulatorial/normas , Continuidade da Assistência ao Paciente/organização & administração , Minnesota
13.
Fertil Steril ; 117(1): 15-21, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34753600

RESUMO

When a diverse group of individuals is working together in the contemporary fertility clinic to provide time-sensitive and complex care for patients, a high degree of coordination and collaboration must take place. When performed dynamically, this process is referred to as teaming. Although the positive impact of teamwork in health care settings has been well established in the literature, the concept of teaming has limited foundation in the clinic. This review will provide an overview of how teaming can be used to improve patient care in today's fertility clinics. Approaches to integrating teaming into the clinic that will be discussed include framing, the creation of a psychologically safe environment for staff input, and facilitating collaborative constructs to support teaming. Best practices to implement teaming and how to address challenges to teaming in today's clinical environment will also be addressed.


Assuntos
Clínicas de Fertilização , Cultura Organizacional , Equipe de Assistência ao Paciente/organização & administração , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/tendências , Calibragem/normas , Atenção à Saúde/organização & administração , Atenção à Saúde/normas , Atenção à Saúde/tendências , Feminino , Clínicas de Fertilização/organização & administração , Clínicas de Fertilização/tendências , Humanos , Masculino , Assistência ao Paciente/normas , Assistência ao Paciente/tendências , Equipe de Assistência ao Paciente/normas , Equipe de Assistência ao Paciente/tendências , Medicina de Precisão/métodos , Medicina de Precisão/tendências , Gravidez
14.
JAMA Intern Med ; 182(1): 42-49, 2022 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-34807241

RESUMO

Importance: Systemic corticosteroids are commonly used in treating severe COVID-19. However, the role of inhaled corticosteroids in the treatment of patients with mild to moderate disease is less clear. Objective: To determine the efficacy of the inhaled steroid ciclesonide in reducing the time to alleviation of all COVID-19-related symptoms among nonhospitalized participants with symptomatic COVID-19 infection. Design, Setting, and Participants: This phase 3, multicenter, double-blind, randomized clinical trial was conducted at 10 centers throughout the US and assessed the safety and efficacy of a ciclesonide metered-dose inhaler (MDI) for treating nonhospitalized participants with symptomatic COVID-19 infection who were screened from June 11, 2020, to November 3, 2020. Interventions: Participants were randomly assigned to receive ciclesonide MDI, 160 µg per actuation, for a total of 2 actuations twice a day (total daily dose, 640 µg) or placebo for 30 days. Main Outcomes and Measures: The primary end point was time to alleviation of all COVID-19-related symptoms (cough, dyspnea, chills, feeling feverish, repeated shaking with chills, muscle pain, headache, sore throat, and new loss of taste or smell) by day 30. Secondary end points included subsequent emergency department visits or hospital admissions for reasons attributable to COVID-19. Results: A total of 413 participants were screened and 400 (96.9%) were enrolled and randomized (197 [49.3%] in the ciclesonide arm and 203 [50.7%] in the placebo arm; mean [SD] age, 43.3 [16.9] years; 221 [55.3%] female; 2 [0.5%] Asian, 47 [11.8%] Black or African American, 3 [0.8%] Native Hawaiian or other Pacific Islander, 345 [86.3%] White, and 1 multiracial individuals [0.3%]; 172 Hispanic or Latino individuals [43.0%]). The median time to alleviation of all COVID-19-related symptoms was 19.0 days (95% CI, 14.0-21.0) in the ciclesonide arm and 19.0 days (95% CI, 16.0-23.0) in the placebo arm. There was no difference in resolution of all symptoms by day 30 (odds ratio, 1.28; 95% CI, 0.84-1.97). Participants who were treated with ciclesonide had fewer subsequent emergency department visits or hospital admissions for reasons related to COVID-19 (odds ratio, 0.18; 95% CI, 0.04-0.85). No participants died during the study. Conclusions and Relevance: The results of this randomized clinical trial demonstrated that ciclesonide did not achieve the primary efficacy end point of reduced time to alleviation of all COVID-19-related symptoms. Trial Registration: ClinicalTrials.gov Identifier: NCT04377711.


Assuntos
Tratamento Farmacológico da COVID-19 , Pregnenodionas/normas , Administração por Inalação , Adolescente , Adulto , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Instituições de Assistência Ambulatorial/tendências , COVID-19/epidemiologia , Método Duplo-Cego , Feminino , Glucocorticoides/normas , Glucocorticoides/uso terapêutico , Humanos , Masculino , Inaladores Dosimetrados , Pessoa de Meia-Idade , Pacientes Ambulatoriais/estatística & dados numéricos , Pregnenodionas/uso terapêutico
15.
Fertil Steril ; 117(1): 22-26, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34809973

RESUMO

Outpatient procedures and flexible staffing models have become prevalent within the ambulatory surgical and procedural spaces of reproductive endocrinology and infertility practice. High volumes of outpatients are treated daily by rotating nurses, surgeons, and anesthesia staff, often with the added layer of trainees present. "Teaming" can allow stable units and ad hoc groups to partner better for enhanced efficiency, effectiveness, and patient experience in routine procedural activities. These skills then can be parlayed into the rare moments of crisis to improve safety outcomes. Teaming concepts, applied in routine and acute scenarios, can optimize clinical operations, patient experience, and outcomes in our reproductive endocrinology and infertility ambulatory procedural and surgical spaces.


Assuntos
Procedimentos Cirúrgicos Ambulatórios/efeitos adversos , Gestão de Recursos da Equipe de Assistência à Saúde , Equipe de Assistência ao Paciente/organização & administração , Adulto , Instituições de Assistência Ambulatorial/organização & administração , Gestão de Recursos da Equipe de Assistência à Saúde/métodos , Gestão de Recursos da Equipe de Assistência à Saúde/organização & administração , Emergências , Feminino , Humanos , Recuperação de Oócitos/efeitos adversos , Equipe de Assistência ao Paciente/normas , Segurança do Paciente , Hemorragia Pós-Operatória/etiologia , Hemorragia Pós-Operatória/terapia
16.
Clin Pediatr (Phila) ; 61(2): 184-187, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34859706

RESUMO

The objective of this study was to characterize the clinical presentation and outcomes of children and adolescents testing positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ambulatory setting. We found that about 8% of children tested positive for SARS-CoV-2, with the large majority being symptomatic (80%). The average age of our population was 12.5 years, and females and males were affected equally. However, African American patients (62%) were substantially more likely to test positive compared with other races. Children in this study tended to have a mild course, mostly presenting with respiratory symptoms, and very few required hospitalization. As the epidemiology of the pandemic evolves, it will be important to monitor the effects that changing variants have on infected children and the impact that vaccination programs have on mitigating infection risk.


Assuntos
Instituições de Assistência Ambulatorial/estatística & dados numéricos , COVID-19/diagnóstico , Adolescente , Instituições de Assistência Ambulatorial/organização & administração , COVID-19/epidemiologia , Criança , Pré-Escolar , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Maryland/epidemiologia , Adulto Jovem
17.
Pediatr Diabetes ; 23(2): 212-218, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34792267

RESUMO

OBJECTIVE: (1) Describe the progression of diabetes mellitus over time in an observational study of Wolfram syndrome, a rare, genetic, neurodegenerative disorder, which often includes diabetes mellitus and is typically diagnosed during childhood or adolescence. (2) Determine whether C-peptide could be used as a marker of diabetes progression in interventional trials for Wolfram syndrome. METHODS: N = 44 (25F/19M) participants with genetically confirmed Wolfram syndrome attended the Washington University Wolfram Research Clinic annually from 2010 to 2019. Medical history, physical examinations, blood sampling, and questionnaires were used to collect data about diabetes mellitus and other components of Wolfram syndrome. Beta-cell function was assessed by determination of C-peptide during a mixed meal tolerance test. Random coefficients models evaluated the rate of progression of C-peptide over time, and power analyses were used to estimate the number of subjects needed to detect a change in C-peptide decline during an intervention trial. RESULTS: 93.2% of patients had diabetes mellitus. Mean HbA1c across all study visits was 7.9%. C-peptide significantly decreased with increasing duration of diabetes mellitus (p < 0.0001); an optimal break point in C-peptide decline was identified to occur between 0.1 and 2.3 years after diabetes mellitus diagnosis. Twenty patients per group (active vs. control) were estimated to be needed to detect a 60% slowing of C-peptide decline during the first 2.3 years following diabetes diagnosis. CONCLUSION: C-peptide declines over time in Wolfram syndrome and could potentially be used as a marker of diabetes progression in interventional studies for Wolfram syndrome, especially within the first 2 years after diabetes diagnosis.


Assuntos
Diabetes Mellitus/etiologia , Síndrome de Wolfram/complicações , Adolescente , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Distribuição de Qui-Quadrado , Criança , Diabetes Mellitus/epidemiologia , Progressão da Doença , Feminino , Humanos , Estudos Longitudinais , Masculino , Washington/epidemiologia , Síndrome de Wolfram/epidemiologia
18.
Prague; Ministry of Health; Dec. 2021. 62 p. tab.
Não convencional em Tcheco | BIGG - guias GRADE | ID: biblio-1451837

RESUMO

As part of the dynamic development of medicine, emergency services are becoming a separate unit with specific requirements for material, technical and personnel equipment, and it is necessary to perceive them as such and clearly adjust the conditions for their operation within inpatient facilities. For this reason and further in connection with the necessity to regulate and cultivate this element operating on the border between ambulatory and inpatient forms of care, emergency incomes will be a new part of the Act on Health Services and implementing legislation. The aim of the recommended procedure is to standardize the organization and functional breakdown of emergency admissions in the Czech Republic as part of the creation of an emergency admissions network as an optimal link between pre-hospital and hospital emergency care. Through unification, it is possible to achieve effective planning in the design and construction of emergency rooms, or reorganization of the existing system of care.


Urgentní príjmy se v rámci dynamického rozvoje medicíny stávají samostatnou jednotkou se specifickými pozadavky na vybavení vecné, technické a personální a je treba je takto vnímat a jednoznacne upravit podmínky pro jejich provozování v rámci luzkových zarízení. Z tohoto duvodu a dále v souvislosti s nutností regulovat a kultivovat tento prvek pusobící na pomezí ambulantní a luzkové formy péce budou urgentní príjmy novou soucástí zákona o zdravotních sluzbách a provádecích právních predpisu. Cílem doporuceného postupu je standardizovat organizaci a funkcní clenení urgentního príjmu v Ceské republice v rámci tvorby síte urgentních príjmu jako optimálního propojení prednemocnicní a nemocnicní neodkladné péce. Unifikací je mozno dosáhnout efektivního plánovaní pri projektování a stavbe urgentního príjmu, resp. reorganizaci stávajícího systému péce.


Assuntos
Administração de Serviços de Saúde , Assistência Ambulatorial/normas , Instituições de Assistência Ambulatorial/organização & administração
19.
Adv Skin Wound Care ; 34(10): 539-541, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34546205

RESUMO

OBJECTIVE: Leg ulcers affect 15% of people with sickle cell disease. However, wound centers typically treat few people with this condition, which makes it difficult to concentrate clinical expertise or support the scientific study of this orphan disease. This article describes an initiative to increase engagement in care through a partnership between wound healing and hematology leadership that led to colocating wound services within a sickle cell clinic. METHODS: Via a retrospective chart review, the authors collected records of all adult patients with sickle cell disease who received wound care in the last decade, including 7 years of wound center data and 3 years of data from the colocated services. Patient and visit characteristics were analyzed using descriptive analytics. RESULTS: The general wound center had previously treated 35 patients with sickle cell ulcers over 7 years. In contrast, colocated services engaged 56 patients within 3 years, including 20 who transferred care and 36 new patients. The majority of patients at the colocated site were women, unlike at the wound center (58% vs 47%, P = .07). Results indicated that 36% of patients healed initial wounds, and 45% had new wound occurrences. CONCLUSIONS: Colocation successfully increases the number of patients with sickle cell ulcers who will engage in wound care at a single site, laying the foundation for clinical studies to improve the evidence base for this difficult-to-treat condition.


Assuntos
Anemia Falciforme/complicações , Hematologia/métodos , Úlcera/etiologia , Cicatrização , Adulto , Idoso , Instituições de Assistência Ambulatorial/organização & administração , Instituições de Assistência Ambulatorial/tendências , Feminino , Hematologia/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Úlcera/terapia
20.
Am J Public Health ; 111(10): 1806-1814, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34529492

RESUMO

Radical health reform movements of the 1960s inspired two widely adopted alternative health care models in the United States: free clinics and community health centers. These groundbreaking institutions attempted to realize bold ideals but faced financial, bureaucratic, and political obstacles. This article examines the history of Fair Haven Community Health Care (FHCHC) in New Haven, Connecticut, an organization that spanned both models and typified innovative aspects of each while resisting the forces that tempered many of its contemporaries' progressive practices. Motivated by a tradition of independence and struggling to address medical neglect in their neighborhood, FHCHC leaders chose not to affiliate with the local academic hospital, a decision that led many disaffected community members to embrace the clinic. The FHCHC also prioritized grant funding over fee-for-service revenue, thus retaining freedom to implement creative programs. Furthermore, the center functioned in an egalitarian manner, enthusiastically employing nurse practitioners and whole-staff meetings, and was largely able to avoid the conflicts that strained other community-controlled organizations. The FHCHC proved unusual among free clinics and health centers and demonstrated strategies similar institutions might employ to overcome common challenges. (Am J Public Health. 2021;111(10): 1806-1814. https://doi.org/10.2105/AJPH.2021.306417).


Assuntos
Instituições de Assistência Ambulatorial/organização & administração , Fortalecimento Institucional/organização & administração , Centros Comunitários de Saúde/organização & administração , Organização do Financiamento/organização & administração , Instituições de Assistência Ambulatorial/economia , Fortalecimento Institucional/economia , Centros Comunitários de Saúde/economia , Connecticut , Organização do Financiamento/economia , Humanos
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