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2.
Value Health ; 24(5): 632-640, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33933231

RESUMO

OBJECTIVE: To estimate the overall quality-adjusted life-years (QALYs) gained by averting 1 coronavirus disease 2019 (COVID-19) infection over the duration of the pandemic. METHODS: A cohort-based probabilistic simulation model, informed by the latest epidemiological estimates on COVID-19 in the United States provided by the Centers for Disease Control and Prevention and literature review. Heterogeneity of parameter values across age group was accounted for. The main outcome studied was QALYs for the infected patient, patient's family members, and the contagion effect of the infected patient over the duration of the pandemic. RESULTS: Averting a COVID-19 infection in a representative US resident will generate an additional 0.061 (0.016-0.129) QALYs (for the patient: 0.055, 95% confidence interval [CI] 0.014-0.115; for the patient's family members: 0.006, 95% CI 0.002-0.015). Accounting for the contagion effect of this infection, and assuming that an effective vaccine will be available in 3 months, the total QALYs gains from averting 1 single infection is 1.51 (95% CI 0.28-4.37) accrued to patients and their family members affected by the index infection and its sequelae. These results were robust to most parameter values and were most influenced by effective reproduction number, probability of death outside the hospital, the time-varying hazard rates of hospitalization, and death in critical care. CONCLUSION: Our findings suggest that the health benefits of averting 1 COVID-19 infection in the United States are substantial. Efforts to curb infections must weigh the costs against these benefits.


Assuntos
COVID-19/prevenção & controle , Custos de Cuidados de Saúde/estatística & dados numéricos , Medicina Preventiva/normas , Anos de Vida Ajustados por Qualidade de Vida , COVID-19/epidemiologia , Análise Custo-Benefício , Custos de Cuidados de Saúde/tendências , Humanos , Pandemias/prevenção & controle , Pandemias/estatística & dados numéricos , Medicina Preventiva/economia , Medicina Preventiva/métodos , Estados Unidos
3.
BMJ Open ; 11(1): e041324, 2021 01 25.
Artigo em Inglês | MEDLINE | ID: mdl-33495253

RESUMO

OBJECTIVES: To advance understanding of how message framing can be used to maximise public support across different pricing policies for alcohol, tobacco and sugary drinks/foods that prevent consumption of cancer-causing products. DESIGN: We designed a 3×4×3 randomised factorial experiment to test responses to messages with three pricing policies, four message frames and three products. SETTING: Online survey panel (Qualtrics) in 2019. PARTICIPANTS: Adults (N=1850) from the UK and USA. INTERVENTIONS: Participants randomly viewed one of 36 separate messages that varied by pricing policy (increasing taxes, getting rid of price discounts, getting rid of low-cost products), four frames and product (alcohol, tobacco, sugary drinks/foods). PRIMARY AND SECONDARY OUTCOME MEASURES: We assessed the relationship between the message characteristics and four dependent variables. Three were related to policy support: (1) increasing taxes on the product mentioned in the message, (2) getting rid of price discounts and special offers on the product mentioned in the message and (3) getting rid of low-cost versions of the product mentioned in the message. One was related to reactance, a psychological response to having one's freedom limited. RESULTS: We found no effect for pricing policy in the message. Frames regarding children and reducing cancer risk moderated some outcomes, showing promise for real-world use. We found differences in support by product and reactance with greatest support and least reactance for tobacco policies, less support and more reactance for alcohol policies, and the least support and most reactance for sugary drinks/foods policies. CONCLUSIONS: Cancer prevention efforts using policy interventions can be informed by the message framing literature. Our results offer insights for cancer prevention advocacy efforts across the UK and USA and highlight that tax versus non-tax approaches to increasing the cost of cancer-causing products result in similar responses from consumers.


Assuntos
Comércio , Atenção à Saúde/economia , Comunicação em Saúde/economia , Neoplasias/prevenção & controle , Medicina Preventiva/economia , Adulto , Criança , Custos e Análise de Custo , Política de Saúde , Humanos , Saúde Pública , Impostos , Reino Unido
4.
Value Health ; 23(10): 1384-1390, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-33032783

RESUMO

OBJECTIVES: This study aimed to investigate whether there was a difference in willingness to pay (WTP) between prevention and treatment for health benefits of equal magnitude. METHODS: We used a web-based survey instrument in a sample of the Swedish general population to perform a contingent valuation study assessing the WTP for prevention and treatment. We analyzed the WTP as a continuous variable using a two-part regression model to adjust for a mass point around 0 and a skewed distribution among respondents with a positive WTP. RESULTS: The study found that people were less willing, on average, to pay at all for prevention than treatment, but those who were willing to pay for prevention had a higher WTP than for treatment. The latter effect was more substantial, and in total mean WTP for prevention was about 85% higher than for treatment. CONCLUSIONS: The findings from this study contribute to the ongoing discussion on the appropriate cost-effectiveness thresholds by adding prevention as a parameter affecting the demand-side value of health improvements. As such, it can provide support to decision makers in healthcare and in health promotion priority setting.


Assuntos
Custos de Cuidados de Saúde , Preferência do Paciente/economia , Medicina Preventiva/economia , Terapêutica/economia , Feminino , Custos de Cuidados de Saúde/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Preferência do Paciente/psicologia , Preferência do Paciente/estatística & dados numéricos , Medicina Preventiva/métodos , Inquéritos e Questionários , Suécia , Terapêutica/métodos , Estados Unidos
5.
J Infect Dis ; 222(Suppl 5): S301-S311, 2020 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-32877548

RESUMO

BACKGROUND: Persons who inject drugs (PWID) are at a disproportionately high risk of HIV infection. We aimed to determine the highest-valued combination implementation strategies to reduce the burden of HIV among PWID in 6 US cities. METHODS: Using a dynamic HIV transmission model calibrated for Atlanta, Baltimore, Los Angeles, Miami, New York City, and Seattle, we assessed the value of implementing combinations of evidence-based interventions at optimistic (drawn from best available evidence) or ideal (90% coverage) scale-up. We estimated reduction in HIV incidence among PWID, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs) for each city (10-year implementation; 20-year horizon; 2018 $ US). RESULTS: Combinations that maximized health benefits contained between 6 (Atlanta and Seattle) and 12 (Miami) interventions with ICER values ranging from $94 069/QALY in Los Angeles to $146 256/QALY in Miami. These strategies reduced HIV incidence by 8.1% (credible interval [CI], 2.8%-13.2%) in Seattle and 54.4% (CI, 37.6%-73.9%) in Miami. Incidence reduction reached 16.1%-75.5% at ideal scale. CONCLUSIONS: Evidence-based interventions targeted to PWID can deliver considerable value; however, ending the HIV epidemic among PWID will require innovative implementation strategies and supporting programs to reduce social and structural barriers to care.


Assuntos
Epidemias/prevenção & controle , Infecções por HIV/epidemiologia , Medicina Preventiva/economia , Anos de Vida Ajustados por Qualidade de Vida , Abuso de Substâncias por Via Intravenosa/reabilitação , Adolescente , Adulto , Cidades/epidemiologia , Efeitos Psicossociais da Doença , Análise Custo-Benefício , Usuários de Drogas/estatística & dados numéricos , Epidemias/economia , Epidemias/estatística & dados numéricos , Feminino , Infecções por HIV/economia , Infecções por HIV/prevenção & controle , Infecções por HIV/transmissão , Teste de HIV/economia , Custos de Cuidados de Saúde , Implementação de Plano de Saúde/economia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Modelos Econômicos , Tratamento de Substituição de Opiáceos/economia , Tratamento de Substituição de Opiáceos/métodos , Profilaxia Pré-Exposição/economia , Profilaxia Pré-Exposição/organização & administração , Prevalência , Medicina Preventiva/organização & administração , Abuso de Substâncias por Via Intravenosa/complicações , Abuso de Substâncias por Via Intravenosa/economia , Estados Unidos/epidemiologia , Adulto Jovem
6.
Am J Public Health ; 110(S2): S186-S190, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32663085

RESUMO

The seminal Consensus Study by the National Academies of Science, Engineering, and Medicine released in September 2019 describes the benefits of integrating health and social care service delivery, underscoring the central role of social determinants of health (SDOH) in health outcomes. Although the report's focus on the integration of health and social care contributes a much needed perspective to the national discourse on SDOH and offers a useful framework for organizing service delivery activities, the omission of prevention and health promotion throughout the report is a substantial limitation.We call for increased attention to and investment in prevention and health promotion in the proposed 5As framework. We contend that effectively addressing SDOH and improving alignment between health and social systems require reconceptualization of the traditional health care workforce and renewed state and national advocacy efforts.A paradigm shift encompassing a broader "workforce for health" that is well trained in prevention, health promotion, and advocacy is critical to addressing SDOH, improving population health outcomes, and achieving health equity. Given their professional mission, training, expertise, and scope of practice, social workers are well positioned to lead this effort.


Assuntos
Promoção da Saúde/economia , Mão de Obra em Saúde , Medicina Preventiva/economia , Serviço Social , Defesa do Consumidor , Ocupações em Saúde , Humanos
7.
J Natl Cancer Inst ; 112(8): 779-791, 2020 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-32277814

RESUMO

BACKGROUND: Health reform and the merits of Medicaid expansion remain at the top of the legislative agenda, with growing evidence suggesting an impact on cancer care and outcomes. A systematic review was undertaken to assess the association between Medicaid expansion and the goals of the Patient Protection and Affordable Care Act in the context of cancer care. The purpose of this article is to summarize the currently published literature and to determine the effects of Medicaid expansion on outcomes during points along the cancer care continuum. METHODS: A systematic search for relevant studies was performed in the PubMed/MEDLINE, EMBASE, Scopus, and Cochrane databases. Three independent observers used an abstraction form to code outcomes and perform a quality and risk of bias assessment using predefined criteria. RESULTS: A total of 48 studies were identified. The most common outcomes assessed were the impact of Medicaid expansion on insurance coverage (23.4% of studies), followed by evaluation of racial and/or socioeconomic disparities (17.4%) and access to screening (14.5%). Medicaid expansion was associated with increases in coverage for cancer patients and survivors as well as reduced racial- and income-related disparities. CONCLUSIONS: Medicaid expansion has led to improved access to insurance coverage among cancer patients and survivors, particularly among low-income and minority populations. This review highlights important gaps in the existing oncology literature, including a lack of studies evaluating changes in treatment and access to end-of-life care following implementation of expansion.


Assuntos
Continuidade da Assistência ao Paciente , Acessibilidade aos Serviços de Saúde/economia , Medicaid , Neoplasias/terapia , Patient Protection and Affordable Care Act , Continuidade da Assistência ao Paciente/economia , Continuidade da Assistência ao Paciente/organização & administração , Continuidade da Assistência ao Paciente/normas , Reforma dos Serviços de Saúde/economia , Reforma dos Serviços de Saúde/métodos , Reforma dos Serviços de Saúde/organização & administração , Acessibilidade aos Serviços de Saúde/legislação & jurisprudência , Acessibilidade aos Serviços de Saúde/organização & administração , Disparidades em Assistência à Saúde/economia , Disparidades em Assistência à Saúde/legislação & jurisprudência , Disparidades em Assistência à Saúde/organização & administração , Disparidades em Assistência à Saúde/estatística & dados numéricos , Humanos , Cobertura do Seguro/economia , Cobertura do Seguro/legislação & jurisprudência , Cobertura do Seguro/organização & administração , Medicaid/economia , Medicaid/legislação & jurisprudência , Medicaid/organização & administração , Grupos Minoritários/estatística & dados numéricos , Neoplasias/economia , Neoplasias/epidemiologia , Patient Protection and Affordable Care Act/economia , Pobreza/economia , Pobreza/estatística & dados numéricos , Medicina Preventiva/economia , Medicina Preventiva/métodos , Medicina Preventiva/organização & administração , Medicina Preventiva/estatística & dados numéricos , Melhoria de Qualidade/economia , Melhoria de Qualidade/organização & administração , Melhoria de Qualidade/normas , Análise de Sobrevida , Assistência Terminal/economia , Assistência Terminal/organização & administração , Assistência Terminal/normas , Estados Unidos/epidemiologia
8.
Am J Manag Care ; 26(3): e70-e75, 2020 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-32181618

RESUMO

OBJECTIVES: To examine the effects of MD-Value in Prevention (MDVIP) enrollment on Medicare expenditures and utilization among fee-for-service (FFS) beneficiaries with diabetes over a 5-year period. STUDY DESIGN: We obtained participating physician and beneficiary enrollment lists from MDVIP and Medicare FFS claims data through the Virtual Research Data Center to compare changes in outcomes, before and after enrollment dates, with those of nonenrolled beneficiaries receiving primary care in the same local market. METHODS: We employed propensity score matching to identify comparison beneficiaries similar in observed characteristics and preenrollment trends. Individual fixed effects were used to control for time-consistent differences between treatment and comparison populations. RESULTS: We found that enrollment is statistically associated with reductions in outpatient expenditures, Medicare expenditures in year 5, emergency department (ED) utilization, and unplanned inpatient admissions, accompanied by significant increases in evaluation and management visits and expenditures. Total Medicare expenditures over the 5-year period, as well as all inpatient admissions, were not statistically different between the MDVIP and comparison groups. CONCLUSIONS: Our finding of reduced unplanned inpatient admissions and ED utilization supports the previous findings regarding MDVIP enrollees. We did not find significant changes in overall third-party expenditures, although savings were estimated in year 5, the last year of observation, and may occur later. Our approach, however, strengthens controls for baseline characteristics of the population and uses a comparison population drawn from the same markets who do not experience the loss of their primary care physician at the time of enrollment.


Assuntos
Diabetes Mellitus/economia , Diabetes Mellitus/terapia , Medicina Preventiva/organização & administração , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Serviço Hospitalar de Emergência/estatística & dados numéricos , Planos de Pagamento por Serviço Prestado/estatística & dados numéricos , Feminino , Gastos em Saúde/estatística & dados numéricos , Serviços de Saúde/economia , Serviços de Saúde/estatística & dados numéricos , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Medicare/estatística & dados numéricos , Medicina Preventiva/economia , Pontuação de Propensão , Fatores Sexuais , Fatores Socioeconômicos , Estados Unidos
9.
Front Biosci (Landmark Ed) ; 25(6): 1132-1171, 2020 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-32114427

RESUMO

Diabetes and atherosclerosis are the predominant causes of stroke and cardiovascular disease (CVD) both in low- and high-income countries. This is due to the lack of appropriate medical care or high medical costs. Low-cost 10-year preventive screening can be used for deciding an effective therapy to reduce the effects of atherosclerosis in diabetes patients. American College of Cardiology (ACC)/American Heart Association (AHA) recommended the use of 10-year risk calculators, before advising therapy. Conventional risk calculators are suboptimal in certain groups of patients because their stratification depends on (a) current blood biomarkers and (b) clinical phenotypes, such as age, hypertension, ethnicity, and sex. The focus of this review is on risk assessment using innovative composite risk scores that use conventional blood biomarkers combined with vascular image-based phenotypes. AtheroEdge™ tool is beneficial for low-moderate to high-moderate and low-risk to high-risk patients for the current and 10-year risk assessment that outperforms conventional risk calculators. The preventive screening tool that combines the image-based phenotypes with conventional risk factors can improve the 10-year cardiovascular/stroke risk assessment.


Assuntos
Artérias Carótidas/diagnóstico por imagem , Complicações do Diabetes/diagnóstico por imagem , Complicações do Diabetes/prevenção & controle , Medicina Preventiva/métodos , Ultrassonografia/métodos , Doenças Cardiovasculares/diagnóstico por imagem , Doenças Cardiovasculares/prevenção & controle , Análise Custo-Benefício , Humanos , Medicina Preventiva/economia , Medição de Risco/economia , Medição de Risco/métodos , Fatores de Risco , Acidente Vascular Cerebral/diagnóstico por imagem , Acidente Vascular Cerebral/prevenção & controle , Ultrassonografia/economia
10.
Diabetes Care ; 43(7): 1593-1616, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33534726

RESUMO

OBJECTIVE: We conducted a systematic review of studies evaluating the cost-effectiveness (CE) of interventions to prevent type 2 diabetes (T2D) among high-risk individuals and whole populations. RESEARCH DESIGN AND METHODS: Interventions targeting high-risk individuals are those that identify people at high risk of developing T2D and then treat them with either lifestyle or metformin interventions. Population-based prevention strategies are those that focus on the whole population regardless of the level of risk, creating public health impact through policy implementation, campaigns, and other environmental strategies. We systematically searched seven electronic databases for studies published in English between 2008 and 2017. We grouped lifestyle interventions targeting high-risk individuals by delivery method and personnel type. We used the median incremental cost-effectiveness ratio (ICER), measured in cost per quality-adjusted life year (QALY) or cost saved to measure the CE of interventions. We used the $50,000/QALY threshold to determine whether an intervention was cost-effective or not. ICERs are reported in 2017 U.S. dollars. RESULTS: Our review included 39 studies: 28 on interventions targeting high-risk individuals and 11 targeting whole populations. Both lifestyle and metformin interventions in high-risk individuals were cost-effective from a health care system or a societal perspective, with median ICERs of $12,510/QALY and $17,089/QALY, respectively, compared with no intervention. Among lifestyle interventions, those that followed a Diabetes Prevention Program (DPP) curriculum had a median ICER of $6,212/QALY, while those that did not follow a DPP curriculum had a median ICER of $13,228/QALY. Compared with lifestyle interventions delivered one-on-one or by a health professional, those offered in a group setting or provided by a combination of health professionals and lay health workers had lower ICERs. Among population-based interventions, taxing sugar-sweetened beverages was cost-saving from both the health care system and governmental perspectives. Evaluations of other population-based interventions-including fruit and vegetable subsidies, community-based education programs, and modifications to the built environment-showed inconsistent results. CONCLUSIONS: Most of the T2D prevention interventions included in our review were found to be either cost-effective or cost-saving. Our findings may help decision makers set priorities and allocate resources for T2D prevention in real-world settings.


Assuntos
Diabetes Mellitus Tipo 2/prevenção & controle , Estado Pré-Diabético/economia , Estado Pré-Diabético/terapia , Medicina Preventiva/economia , Medicina Preventiva/métodos , Adulto , Idoso , Redes Comunitárias/economia , Redes Comunitárias/organização & administração , Redes Comunitárias/estatística & dados numéricos , Análise Custo-Benefício , Diabetes Mellitus Tipo 2/economia , Diabetes Mellitus Tipo 2/epidemiologia , Endocrinologia/economia , Endocrinologia/métodos , Endocrinologia/tendências , Custos de Cuidados de Saúde , Gastos em Saúde/estatística & dados numéricos , Promoção da Saúde/economia , Promoção da Saúde/métodos , Promoção da Saúde/estatística & dados numéricos , Humanos , Estilo de Vida , Metformina/uso terapêutico , Pessoa de Meia-Idade , Educação de Pacientes como Assunto/economia , Educação de Pacientes como Assunto/organização & administração , Educação de Pacientes como Assunto/estatística & dados numéricos , Vigilância da População/métodos , Estado Pré-Diabético/epidemiologia , Anos de Vida Ajustados por Qualidade de Vida , Fatores de Risco , Comportamento de Redução do Risco , Adulto Jovem
11.
Diabetes Care ; 43(3): 563-571, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31882408

RESUMO

OBJECTIVE: Previous randomized trials found that treating periodontitis improved glycemic control in patients with type 2 diabetes (T2D), thus lowering the risks of developing T2D-related microvascular diseases and cardiovascular disease (CVD). Some payers in the U.S. have started covering nonsurgical periodontal treatment for those with chronic conditions, such as diabetes. We sought to identify the cost-effectiveness of expanding periodontal treatment coverage among patients with T2D. RESEARCH DESIGN AND METHODS: A cost-effectiveness analysis was conducted to estimate lifetime costs and health gains using a stochastic microsimulation model of oral health conditions, T2D, T2D-related microvascular diseases, and CVD of the U.S. POPULATION: Model parameters were obtained from the nationally representative National Health and Nutrition Examination Survey (NHANES) (2009-2014) and randomized trials of periodontal treatment among patients with T2D. RESULTS: Expanding periodontal treatment coverage among patients with T2D and periodontitis would be expected to avert tooth loss by 34.1% (95% CI -39.9, -26.5) and microvascular diseases by 20.5% (95% CI -31.2, -9.1), 17.7% (95% CI -32.7, -4.7), and 18.4% (95% CI -34.5, -3.5) for nephropathy, neuropathy, and retinopathy, respectively. Providing periodontal treatment to the target population would be cost saving from a health care perspective at a total net savings of $5,904 (95% CI -6,039, -5,769) with an estimated gain of 0.6 quality-adjusted life years per capita (95% CI 0.5, 0.6). CONCLUSIONS: Providing nonsurgical periodontal treatment to patients with T2D and periodontitis would be expected to significantly reduce tooth loss and T2D-related microvascular diseases via improved glycemic control. Encouraging patients with T2D and poor oral health conditions to receive periodontal treatment would improve health outcomes and still be cost saving or cost-effective.


Assuntos
Diabetes Mellitus Tipo 2/terapia , Angiopatias Diabéticas/prevenção & controle , Modelos Econômicos , Periodontite/terapia , Doenças Vasculares/prevenção & controle , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Cardiovasculares/economia , Doenças Cardiovasculares/epidemiologia , Doenças Cardiovasculares/prevenção & controle , Simulação por Computador , Análise Custo-Benefício , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/economia , Diabetes Mellitus Tipo 2/epidemiologia , Angiopatias Diabéticas/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais/estatística & dados numéricos , Periodontite/complicações , Periodontite/economia , Periodontite/epidemiologia , Medicina Preventiva/economia , Medicina Preventiva/métodos , Medicina Preventiva/estatística & dados numéricos , Anos de Vida Ajustados por Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto/economia , Ensaios Clínicos Controlados Aleatórios como Assunto/estatística & dados numéricos , Estados Unidos/epidemiologia , Doenças Vasculares/economia , Doenças Vasculares/epidemiologia
12.
Pathog Glob Health ; 113(7): 291-296, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31868571

RESUMO

Maintaining high vaccination coverage is important in order to protect the individual and the community. Mandatory vaccination is an option in case of declining coverage. Widely used in the USA, it is considered a rather controversial issue in Europe. In Italy, after a decrease of vaccination coverage for the hexavalent and the MPR vaccine under the optimal threshold, a new law, which extended the number of mandatory vaccines from 4 to 10 and reinforced coercive measures, was introduced in July 2017. After 2 years, vaccination coverage increased for all mandatory vaccines and for the other two recommended vaccines (anti-pneumococcal and anti-meningococcal C). Although it is not possible to disentangle the role of other factors contributing to the positive outcome, consistently with the results of studies conducted in the USA, vaccine mandates appeared to be successful in increasing vaccination coverage in Italy. The long-term sustainability of the effect of mandatory vaccination and the potential negative drawbacks of the coercive measures need to be evaluated to generate scientific evidence in public health.


Assuntos
Programas Obrigatórios/legislação & jurisprudência , Vacinação/legislação & jurisprudência , Criança , Pré-Escolar , Humanos , Lactente , Itália , Programas Obrigatórios/economia , Medicina Preventiva/economia , Medicina Preventiva/legislação & jurisprudência , Vacinação/economia
13.
Am J Prev Med ; 57(6): 818-825, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31753263

RESUMO

INTRODUCTION: Poor diet and inadequate physical activity are common contributors to preventable death in the U.S. This paper provides a summary of the NIH-sponsored research on disease prevention that underlies public health and clinical recommendations to improve diet and physical activity. METHODS: A representative sample (n=11,082) of research grants and cooperative agreements (research projects) representing the NIH prevention research portfolio between 2012 and 2017 were hand coded by trained analysts in 2017-2018. This manuscript describes the rationale(s), exposure(s), outcome(s), population(s), and study design(s) in prevention research focused on diet and physical activity and compares this research to identified research gaps in the field. RESULTS: A relatively stable 7.8% (95% CI=7.0%, 8.8%) and 5.0% (95% CI=4.4%, 5.7%) of the NIH prevention research projects were focused on diet and physical activity, respectively, during 2012-2017. These projects often explored diet and physical activity together in the context of obesity, included observational studies, and focused on a general adult population. Few of these projects focused on development of improved assessment methods. Approximately 50% of these studies were related to research gaps identified by the 2015 Dietary or 2018 Physical Activity Guidelines Advisory Committee Scientific Reports. CONCLUSIONS: Opportunities exist for more engagement by NIH and scientific investigators in diet- and physical activity-focused prevention research, particularly around assessment and known research gaps.


Assuntos
Exercício Físico , Comportamento Alimentar , National Institutes of Health (U.S.)/economia , Medicina Preventiva/métodos , Apoio à Pesquisa como Assunto , Adulto , Comitês Consultivos , Idoso , Pesquisa Biomédica/economia , Pesquisa Biomédica/organização & administração , Pesquisa Biomédica/estatística & dados numéricos , Criança , Feminino , Humanos , Masculino , Medicina Preventiva/economia , Medicina Preventiva/estatística & dados numéricos , Estados Unidos , Adulto Jovem
14.
Health Aff (Millwood) ; 38(8): 1366-1376, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31381384

RESUMO

TRICARE provides health care benefits to nearly two million children of active duty, retired, National Guard, and reserve service members. Child health advocates and congressional reports have raised questions regarding the adequacy of these benefits, compared with other sources of children's health insurance. To help address these questions, we compared TRICARE benefits with benefits from Medicaid and Marketplace plans because they represent alternative sources of coverage for many of the families enrolled in TRICARE. Overall, we found that TRICARE benefits fell in the middle-between Medicaid plans' more comprehensive benefits with no cost sharing and Marketplace plans' more restrictive benefits with higher cost sharing.


Assuntos
Custo Compartilhado de Seguro , Medicaid/economia , Serviços de Saúde Militar , Assistência Ambulatorial/economia , Assistência Ambulatorial/organização & administração , Criança , Custo Compartilhado de Seguro/economia , Serviços Médicos de Emergência/economia , Serviços Médicos de Emergência/organização & administração , Humanos , Benefícios do Seguro/economia , Seguro Saúde/economia , Seguro Saúde/organização & administração , Medicaid/organização & administração , Serviços de Saúde Militar/economia , Medicina Preventiva/economia , Medicina Preventiva/organização & administração , Autorização Prévia/economia , Autorização Prévia/organização & administração , Estados Unidos
15.
J Gen Intern Med ; 34(11): 2634-2636, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31452041

RESUMO

One increasingly popular strategy for addressing avoidable healthcare costs is to couple "hotspotting" with interventions that deliver expanded, more intense primary care services to high-cost patient populations. While there is rationale for such intensive primary care programs, early results have been lackluster. Geoffrey Rose's preventive medicine strategy provides insight about a potential explanation: that the narrow scope of these initiatives on small groups of high-cost patients may inherently prevent them from achieving overall cost reductions across entire patient populations. While additional work and results from innovative non-healthcare-based interventions are needed, healthcare organizations may benefit from instead investing in broader interventions that impact patients across cost levels, including average- or low-cost patients.


Assuntos
Custos de Cuidados de Saúde , Atenção Primária à Saúde/economia , Humanos , Medicina Preventiva/economia , Atenção Primária à Saúde/organização & administração , Medição de Risco
16.
Diabetologia ; 62(8): 1319-1328, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31270584

RESUMO

The global epidemic of type 2 diabetes has prompted numerous studies and public health efforts to reduce its development. A variety of interventions, including lifestyle modifications and pharmacological agents directed at ameliorating the major risk factors for type 2 diabetes, are of proven efficacy in reducing the development of type 2 diabetes in people with impaired glucose tolerance. While prevention of the hyperglycaemia characteristic of diabetes is arguably an important, clinically relevant outcome, a more compelling outcome with greater clinical significance is the prevention or reduction of the relatively diabetes-specific microvascular and less-specific cardiovascular disease (CVD) complications associated with diabetes. These complications cause the majority of morbidity and excess mortality associated with diabetes. Any reduction in diabetes should, logically, also reduce the occurrence of its long-term complications; however, most diabetes prevention trials have not been of sufficient duration to allow such an evaluation. The limited long-term data, largely from the Da Qing Diabetes Prevention Study (DQDPS) and the Diabetes Prevention Program (DPP) and their respective follow-up studies (DQDPOS and DPPOS), suggest a reduction in microvascular complications and amelioration of CVD risk factors. Only the DQDPOS and Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) studies have shown a reduction in CVD events and only DQDPOS has demonstrated a decrease in CVD and overall mortality. While these limited data are promising, whether diabetes prevention directly reduces complication-related morbidity and mortality remains unclear. Longer follow-up of prevention studies is needed to supplement the limited current clinical trial data, to help differentiate the effects of diabetes prevention itself from the means used to reduce diabetes development and to understand the balance among benefits, risks and costs of prevention.


Assuntos
Doenças Cardiovasculares/prevenção & controle , Complicações do Diabetes/prevenção & controle , Diabetes Mellitus Tipo 2/prevenção & controle , Medicina Preventiva/métodos , Aterosclerose/tratamento farmacológico , Doenças Cardiovasculares/complicações , Doenças Cardiovasculares/tratamento farmacológico , Ensaios Clínicos como Assunto , Análise Custo-Benefício , Diabetes Mellitus Tipo 2/tratamento farmacológico , Seguimentos , Intolerância à Glucose/complicações , Humanos , Hipoglicemiantes/uso terapêutico , Estilo de Vida , Metformina/uso terapêutico , Microcirculação , Medicina Preventiva/economia , Ramipril/uso terapêutico , Fatores de Risco , Rosiglitazona/uso terapêutico , Resultado do Tratamento
17.
BMJ Open ; 9(7): e029832, 2019 07 23.
Artigo em Inglês | MEDLINE | ID: mdl-31340973

RESUMO

INTRODUCTION: Childhood respiratory syncytial virus (RSV) infection is a global phenomenon that can lead to fatal respiratory illness. Palivizumab is a drug that is routinely used in affluent countries as a prophylaxis against RSV infection; nevertheless, breakthrough infections are often reported. In light of new findings on potential RSV resistance to palivizumab, an up-to-date synthesis of evidence on effectiveness is needed. Furthering existing reviews, a broadened scope to better reflect effectiveness in a 'real world' clinical context is also important. This systematic review and meta-analysis will enhance our understanding of the effectiveness of palivizumab in varying populations of children. Findings from this review will inform recommendations for best practices regarding palivizumab use for childhood RSV infection as well as research priorities in RSV vaccine development. METHODS AND ANALYSIS: We will conduct a systematic review of primary population-based studies that examine the incidence of palivizumab breakthrough infections in children, published between 1997 to present. In collaboration with a research librarian, four electronic databases (MEDLINE, Embase, Cochrane Library, Web of Science) and additional sources will be searched. Study screening and quality assessment will be performed in duplicate. Data will be extracted by one reviewer, with partial and random verification by a second reviewer. The primary outcomes to assess breakthrough RSV infection will be hospitalisation, length of stay and the need for intensive care unit admission and mechanical ventilation in children receiving palivizumab. The secondary outcome will be RSV-associated mortality. We will conduct a meta-analysis using pooled effectiveness data, and include subgroup analyses by patient comorbidities and drug compliance. Sensitivity analyses for risk of bias and study design will also be performed. ETHICS AND DISSEMINATION: This systematic review will only include data from previously published literature and is therefore exempt from ethics approval. Final results will be disseminated through peer-reviewed publication and presented at academic conferences and scientific meetings engaging paediatric researchers and healthcare providers. Should findings from this review necessitate updates to current clinical practice guidelines, we intend to establish a working group to engage relevant health administrators and decision makers. PROSPERO REGISTRATION NUMBER: CRD42019122120.


Assuntos
Antivirais/uso terapêutico , Palivizumab/uso terapêutico , Infecções por Vírus Respiratório Sincicial/prevenção & controle , Criança , Hospitalização , Humanos , Unidades de Terapia Intensiva , Metanálise como Assunto , Medicina Preventiva/economia , Projetos de Pesquisa , Infecções por Vírus Respiratório Sincicial/mortalidade , Vírus Sinciciais Respiratórios , Revisões Sistemáticas como Assunto
18.
Bull World Health Organ ; 97(6): 415-422, 2019 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-31210679

RESUMO

Thailand's policy on universal health coverage (UHC) has made good progress since its inception in 2002. Every Thai citizen is now entitled to essential preventive, curative and palliative health services at all life stages. Like its counterparts elsewhere, however, the policy faces challenges. A predominantly tax-financed system in a nation with a high proportion of people living in poverty will always strive to contain rising costs. Disparities exist among the different health insurance schemes that provide coverage for Thai citizens. National health expenditure is heavily borne by the government, primarily to reduce financial barriers to access for the poor. The population is ageing and the disease profiles of the population are changing alongside the modernization of Thai people's lifestyles. Thailand is now aiming to enhance and sustain its UHC policy. We examine the merits of different policy options and aim to identify the most promising and feasible way to enhance and sustain UHC. We argue that developing the existing primary care system in Thailand has the greatest potential to provide more self-sustaining, efficient, equitable and effective UHC. Primary care needs to move from its traditional role of providing basic disease-based care, to being the first point of contact in an integrated, coordinated, community-oriented and person-focused care system, for which the national health budget should be prioritized.


La politique de couverture sanitaire universelle de la Thaïlande a bien progressé depuis sa création en 2002. Chaque citoyen thaïlandais a désormais le droit à des services de santé préventifs, curatifs et palliatifs essentiels à tous les stades de sa vie. Néanmoins, à l'instar de ses équivalents dans d'autres pays, cette politique fait face à des difficultés. Un système principalement financé par l'impôt dans un pays où une forte proportion de personnes vit dans la pauvreté devra toujours s'efforcer de limiter l'augmentation des coûts. Des disparités existent entre les différents régimes d'assurance maladie qui fournissent une couverture aux citoyens thaïlandais. Les dépenses nationales de santé sont largement prises en charge par le gouvernement, principalement pour réduire les obstacles financiers qui empêchent les pauvres d'accéder aux services de santé. La population vieillit et le profil des maladies de la population évolue en même temps que les modes de vie des Thaïlandais se modernisent. La Thaïlande a désormais l'intention de renforcer sa politique de couverture sanitaire universelle et d'assurer sa pérennité. Nous examinons les avantages de différentes possibilités d'action et cherchons à identifier la solution la plus prometteuse et réalisable pour renforcer et assurer la pérennité de la couverture sanitaire universelle. Nous soutenons que le développement du système existant de soins de santé primaires en Thaïlande est la meilleure solution pour fournir une couverture sanitaire universelle plus autonome, efficiente, équitable et efficace. Les soins primaires doivent s'écarter de leur rôle traditionnel qui est de fournir des soins de base axés sur une maladie pour être le premier point de contact dans un système de soins intégré, coordonné, orienté vers la communauté et axé sur la personne, ce qui nécessite de donner une priorité élevée au budget national de santé.


La política de Tailandia sobre la cobertura sanitaria universal (CSU) ha progresado mucho desde su creación en 2002. Todos los ciudadanos tailandeses tienen ahora derecho a servicios esenciales de salud preventiva, curativa y paliativa en todas las etapas de la vida. Sin embargo, al igual que sus homólogas en otros lugares, la política se enfrenta a desafíos. Un sistema financiado en su mayoría por impuestos en un país con una alta proporción de personas que viven en la pobreza siempre tendrá que esforzarse para limitar el aumento de los costes. Existen disparidades entre los diferentes planes de seguros sanitarios que ofrecen cobertura a los ciudadanos tailandeses. El gasto nacional en salud lo soporta en gran medida el gobierno, principalmente para reducir las barreras financieras al acceso de los pobres. La población envejece y los perfiles de enfermedad de la población cambian al mismo tiempo que se modernizan los estilos de vida de los habitantes de Tailandia. Tailandia aspira ahora a mejorar y mantener su política de CSU. Se han examinado los méritos de las diferentes opciones de políticas para así identificar la manera más prometedora y factible de mejorar y sostener la CSU. Se sostiene que el desarrollo del sistema de atención primaria de salud existente en Tailandia tiene el mayor potencial para proporcionar una atención primaria de salud más autosuficiente, eficiente, equitativa y eficaz. La atención primaria debe pasar de su función tradicional de proporcionar atención básica basada en la enfermedad a ser el primer punto de contacto en un sistema de atención integral, coordinado, orientado a la comunidad y centrado en las personas, para lo cual se debe dar prioridad al presupuesto nacional de salud.


Assuntos
Acessibilidade aos Serviços de Saúde/economia , Financiamento da Assistência à Saúde , Atenção Primária à Saúde , Cobertura Universal do Seguro de Saúde/economia , Política de Saúde , Humanos , Medicina Preventiva/economia , Medicina Preventiva/métodos , Atenção Primária à Saúde/economia , Impostos , Tailândia
19.
Eur J Health Econ ; 20(6): 869-878, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30953217

RESUMO

BACKGROUND: Research has shown that a small proportion of patients account for the majority of health care spending. The objective of this analysis was to determine the amount and proportion of preventable acute care spending among high-cost patients. METHODS: We examined a population-based sample of all adult high-cost patients using linked administrative health care data housed at ICES in Toronto, Ontario. High-cost patients were defined as those in and above the 90th percentile of the cost distribution. Preventable acute care (emergency department visits and hospitalisations) was defined using validated algorithms. We estimated costs of preventable and non-preventable acute care for high- and non-high-cost patients by category of visit/condition. We replicated our analysis for persistent high-cost patients and high-cost patients under 65 years and those 65 years and older. RESULTS: We found that 10% of all acute care spending among high-cost patients was considered preventable; this figure was higher for non-high-cost patients (25%). The proportion of preventable acute care spending was higher for persistent high-cost patients (14%) and those 65 years and older (12%). Among ED visits, the largest portion of preventable care spending was for primary care treatable conditions; for hospitalisations, the highest proportions of preventable care spending were for COPD, bacterial pneumonia and urinary tract infections. CONCLUSIONS: Although high-cost patients account for a substantial proportion of health care costs, there seems to be limited scope to prevent acute care spending among this patient population. Nonetheless, care coordination and improved access to primary care, and disease prevention may prevent some acute care.


Assuntos
Doença Aguda/economia , Custos de Cuidados de Saúde/estatística & dados numéricos , Medicina Preventiva/economia , Sistema de Fonte Pagadora Única/economia , Idoso , Estudos Transversais , Bases de Dados Factuais , Serviço Hospitalar de Emergência/economia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ontário
20.
Soc Sci Med ; 228: 202-210, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30925394

RESUMO

Prevention is an attractive idea to policymakers in theory, particularly in health where the burden of spending and care is increasingly taken up by complex and chronic conditions associated with lifestyle choices. However, prevention in general, and preventive health in particular, has proven hard to implement in practice. In this paper, we look to one tangible legacy of the recent rise of the prevention agenda: agencies with responsibility for preventive health policy. We ask how this form of institutionalizing preventive health happens in practice, and what consequences it has for the advancement of the prevention agenda. We draw on qualitative data to compare the trajectories of newly formed agencies in Australia, New Zealand and England. We find that building and maintaining legitimacy for such agencies may come at the expense of quick progress or radical action in service of the prevention agenda.


Assuntos
Política , Medicina Preventiva/métodos , Condições Sociais/estatística & dados numéricos , Austrália , Doença Crônica , Inglaterra , Política de Saúde/tendências , Humanos , Nova Zelândia , Medicina Preventiva/economia , Medicina Preventiva/tendências , Saúde Pública/economia , Saúde Pública/métodos , Saúde Pública/tendências , Condições Sociais/economia
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