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Can J Ophthalmol ; 40(5): 611-5, 2005 10.
Artigo em Inglês | MEDLINE | ID: mdl-16391626

RESUMO

CASE REPORT: We present a case of congenital choroidal mass in a male infant with multiple cutaneous pigmented lesions. Enucleation performed in the first weeks of life confirmed the diagnosis of diffuse uveal malignant melanoma with extraocular extension. The patient was also treated with 5 cycles of chemotherapy. He subsequently developed cutaneous and ocular pigmented lesions, including 2 choroidal nevi located within the posterior pole and a benign conjunctival lesion in the opposite eye, in addition to malignant melanoma of the skin. COMMENTS: At 10 years follow-up, the child is clinically well with no evidence of further malignancy. We believe this represents the fourth case ever reported in the literature and the longest follow-up of a congenital malignant melanoma originating within the eye.


Assuntos
Melanoma/congênito , Neoplasias Cutâneas/secundário , Neoplasias Uveais/congênito , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Ciclofosfamida/uso terapêutico , Dactinomicina/uso terapêutico , Enucleação Ocular , Seguimentos , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Melanoma/tratamento farmacológico , Melanoma/secundário , Invasividade Neoplásica , Indução de Remissão , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Uveais/tratamento farmacológico , Neoplasias Uveais/patologia , Vincristina/uso terapêutico
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