RESUMO
ABSTRACT CONTEXT: Various skin manifestations have been reported in coronavirus disease. It may be difficult to determine the etiology of these lesions in view of the increased frequency of handwashing during the pandemic, along with occurrences of irritant contact dermatitis and allergic contact dermatitis due to disinfectant use; usage of herbal medicine and supplements to strengthen the immune system; and urticarial or maculopapular drug eruptions due to COVID-19 treatment. The variety of associated skin manifestations seen with COVID-19 makes it challenging to identify virus-specific skin manifestations. Petechiae, purpura, acrocyanosis and necrotic and non-necrotic purpura, which can be considered as manifestations of vascular involvement on the skin, have been reported. CASE REPORT: Here, we report a case of eruptive cherry angiomas, which was thought to have developed due to COVID-19, with a papulovesicular rash on distal extremities that progressed over time to reticular purpura. CONCLUSION: The case presented had a papulovesicular rash at the onset, which evolved to retiform purpura, and eruptive cherry angiomas were observed. It should be kept in mind that dermatological signs may vary in patients with COVID-19.
Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Púrpura/virologia , Pele/virologia , Dermatopatias Virais/virologia , Exantema/virologia , COVID-19/complicações , COVID-19/virologia , Hemangioma/virologia , Pele/efeitos dos fármacos , Pele/patologia , Resultado do Tratamento , Dermatopatias Virais/diagnóstico , Dermatopatias Virais/terapia , Teste para COVID-19 , SARS-CoV-2 , COVID-19/tratamento farmacológico , COVID-19/terapiaRESUMO
CONTEXT: Various skin manifestations have been reported in coronavirus disease. It may be difficult to determine the etiology of these lesions in view of the increased frequency of handwashing during the pandemic, along with occurrences of irritant contact dermatitis and allergic contact dermatitis due to disinfectant use; usage of herbal medicine and supplements to strengthen the immune system; and urticarial or maculopapular drug eruptions due to COVID-19 treatment. The variety of associated skin manifestations seen with COVID-19 makes it challenging to identify virus-specific skin manifestations. Petechiae, purpura, acrocyanosis and necrotic and non-necrotic purpura, which can be considered as manifestations of vascular involvement on the skin, have been reported. CASE REPORT: Here, we report a case of eruptive cherry angiomas, which was thought to have developed due to COVID-19, with a papulovesicular rash on distal extremities that progressed over time to reticular purpura. CONCLUSION: The case presented had a papulovesicular rash at the onset, which evolved to retiform purpura, and eruptive cherry angiomas were observed. It should be kept in mind that dermatological signs may vary in patients with COVID-19.
Assuntos
COVID-19/complicações , COVID-19/virologia , Exantema/virologia , Hemangioma/virologia , Púrpura/virologia , Dermatopatias Virais/virologia , Pele/virologia , COVID-19/terapia , Teste para COVID-19 , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , SARS-CoV-2 , Pele/efeitos dos fármacos , Pele/patologia , Dermatopatias Virais/diagnóstico , Dermatopatias Virais/terapia , Resultado do Tratamento , Tratamento Farmacológico da COVID-19Assuntos
Infecções por Coronavirus/diagnóstico , Coronavirus/isolamento & purificação , Exantema , Pneumonia Viral/diagnóstico , Púrpura/virologia , Adulto , Betacoronavirus , COVID-19 , Infecções por Coronavirus/complicações , Humanos , Perna (Membro) , Masculino , Pandemias , Pneumonia Viral/complicações , Púrpura/diagnóstico , SARS-CoV-2RESUMO
IMPORTANCE: The Zika virus epidemic has been declared a public health emergency of international concern by the World Health Organization. We describe the mucocutaneous features and histologic correlation in a patient with the acute Zika virus infection. OBSERVATIONS: We observed the presence of a diffuse papular descending eruption, petechiae on the palate, and hyperemic sclerae in a 44-year-old man returning from Puerto Rico with confirmatory testing for the Zika virus. CONCLUSIONS AND RELEVANCE: A detailed awareness of mucocutaneous findings associated with Zika virus infection will support its early recognition and will facilitate elimination of Zika infection from consideration for concerned patients who present with other, more common erythematous eruptions.
Assuntos
Mucosa/patologia , Dermatopatias Virais/patologia , Infecção por Zika virus/patologia , Doença Aguda , Adulto , Humanos , Hiperemia/virologia , Masculino , Mucosa/virologia , Porto Rico , Púrpura/virologia , Esclera/patologia , ViagemRESUMO
Papular-purpuric gloves and socks syndrome is a rare, highly contagious dermatosis caused by parvovirus B19, which may result in the abrupt cessation of red blood cell production in patients with preexisting hematological diseases. It affects predominantly children and young adults and has an unusual presentation.
Assuntos
Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , Infecções por Parvoviridae/complicações , Parvovirus B19 Humano , Púrpura/virologia , Dermatopatias Virais/virologia , Adulto , Feminino , Humanos , Púrpura/diagnóstico , SíndromeRESUMO
Papular-purpuric gloves and socks syndrome is a rare, highly contagious dermatosis caused by parvovirus B19, which may result in the abrupt cessation of red blood cell production in patients with preexisting hematological diseases. It affects predominantly children and young adults and has an unusual presentation.
A síndrome "gloves and socks" pápulo-purpúrica é uma dermatose incomum, altamente contagiosa, causada pelo parvovírus B19, que pode provocar interrupção aguda da produção de glóbulos vermelhos em pacientes com doenças hematológicas preexistentes. Acomete, principalmente, crianças e jovens, e tem uma apresentaçao nao-usual.
Assuntos
Humanos , Feminino , Adulto , Púrpura/virologia , Parvovirus B19 Humano , Dermatopatias Virais/virologia , Infecções por Parvoviridae/complicações , Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , Púrpura/diagnóstico , SíndromeRESUMO
Two atypical cases of parvovirus B19 infection occurred consecutively within a family. A 14 year-old patient presented an extended papular-purpuric "gloves and socks" syndrome and two weeks later his mother developed a predominantly unilateral purpuric rash in the limbs with severe malaise. Specific IgM antibodies in the boy and polymerase chain reaction (PCR) and serology in the mother, confirmed parvovirus B19 infection. We emphasize the variable presentation of B19 infection within a family. The importance of etiologic studies in the presence of atypical exanthemas and the utility of PCR in the diagnosis of B19 are underscored.
Assuntos
Eritema Infeccioso/diagnóstico , Exantema/diagnóstico , Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , Parvovirus B19 Humano , Púrpura/diagnóstico , Adolescente , Adulto , Eritema Infeccioso/virologia , Exantema/virologia , Família , Feminino , Dermatoses do Pé/patologia , Dermatoses da Mão/patologia , Humanos , Masculino , Parvovirus B19 Humano/genética , Reação em Cadeia da Polimerase , Púrpura/virologia , SíndromeRESUMO
Two atypical cases of parvovirus B19 infection occurred consecutively within a family. A 14 year-old patient presented an extended papular-purpuric "gloves and socks" syndrome and two weeks later his mother developed a predominantly unilateral purpuric rash in the limbs with severe malaise. Specific IgM antibodies in the boy and polymerase chain reaction (PCR) and serology in the mother, confirmed parvovirus B19 infection. We emphasize the variable presentation of B19 infection within a family. The importance ofetiologic studies in the presence of atypical exanthemas and the utility of PCR in the diagnosis ofB19 are undesrscored.
Assuntos
Adolescente , Adulto , Feminino , Humanos , Masculino , Eritema Infeccioso/diagnóstico , Exantema/diagnóstico , Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , Púrpura/diagnóstico , Eritema Infeccioso/virologia , Exantema/virologia , Família , Dermatoses do Pé/patologia , Dermatoses da Mão/patologia , /genética , Reação em Cadeia da Polimerase , Púrpura/virologia , SíndromeRESUMO
Papular-purpuric "gloves and socks" syndrome (PPGSS) is a novel, rare, self-limiting dermatosis caused by human parvovirus B19. It consists of pruritic edema and erythema of the hands and feet in a gloves-and-socks distribution, and it is associated with oral lesions and fever. We present a case of PPGSS in a 22-year-old Brazilian woman. Clinical and laboratory evaluation, including serological tests, PCR and gene sequencing, confirmed the presence of human parvovirus B19.
Assuntos
Eritema Infeccioso/virologia , Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , Parvovirus B19 Humano/isolamento & purificação , Púrpura/virologia , Adulto , DNA Viral , Ensaio de Imunoadsorção Enzimática , Eritema Infeccioso/diagnóstico , Feminino , Dermatoses do Pé/diagnóstico , Dermatoses da Mão/diagnóstico , Humanos , Parvovirus B19 Humano/genética , Filogenia , Reação em Cadeia da Polimerase , Púrpura/diagnóstico , SíndromeRESUMO
Papular-purpuric "gloves and socks" syndrome (PPGSS) is a novel, rare, self-limiting dermatosis caused by human parvovirus B19. It consists of pruritic edema and erythema of the hands and feet in a gloves-and-socks distribution, and it is associated with oral lesions and fever. We present a case of PPGSS in a 22-year-old Brazilian woman. Clinical and laboratory evaluation, including serological tests, PCR and gene sequencing, confirmed the presence of human parvovirus B19.
Assuntos
Adulto , Feminino , Humanos , Eritema Infeccioso/virologia , Dermatoses do Pé/virologia , Dermatoses da Mão/virologia , /isolamento & purificação , Púrpura/virologia , DNA Viral , Ensaio de Imunoadsorção Enzimática , Eritema Infeccioso/diagnóstico , Dermatoses do Pé/diagnóstico , Dermatoses da Mão/diagnóstico , Filogenia , Reação em Cadeia da Polimerase , /genética , Púrpura/diagnóstico , SíndromeRESUMO
We present a case of papular-purpuric "gloves and socks" syndrome (PPGSS) in an adult male with acute parvovirus B19 infection. The patient displayed the classical features of fever, oral lesions, and purpura on hands and feet, but the purpuric lesions on the feet evolved to superficial skin necrosis, a feature not previously described in this syndrome. We believe this is the first reported case of PPGSS occurring in Brazil.
Assuntos
Acrodermatite/virologia , Infecções por Papillomavirus/diagnóstico , Parvovirus B19 Humano/isolamento & purificação , Púrpura/virologia , Acrodermatite/diagnóstico , Acrodermatite/imunologia , DNA Viral/análise , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , Pessoa de Meia-Idade , Infecções por Papillomavirus/imunologia , Púrpura/diagnóstico , Púrpura/imunologia , SíndromeRESUMO
We present a case of papular-purpuric "gloves and socks" syndrome (PPGSS) in an adult male with acute parvovirus B19 infection. The patient displayed the classical features of fever, oral lesions, and purpura on hands and feet, but the purpuric lesions on the feet evolved to superficial skin necrosis, a feature not previously described in this syndrome. We believe this is the first reported case of PPGSS occurring in Brazil