Toxocariasis ocular. A propósito de un caso / Ocular toxocariasis. Case report

RESUMEN Se presentó un caso clínico de un paciente de seis años de edad, con toxocariasis ocular. La manifestación clínica fue disminución de la agudeza visual monocular. El fondo de ojo izquierdo mostró un granuloma retiniano periférico, asociado a un desgarro retiniano perilesional. El examen oftalmológico confirmó el diagnóstico de Toxocara ocular. El paciente fue tratado posteriormente mediante corticoides sistémicos y fotocoagulación láser focal en el desgarro retiniano (AU).

ABSTRACT We present the clinical case of a male patient, aged 6 years, with ocular toxocariasis. The clinical manifestation was monocular visual acuity decrease. The left ocular fundus showed a peripheral retina granuloma, associated to a perilesional retinal tear. The ophthalmological examination confirmed the diagnosis of ocular Toxocara. After that the patient was treated using systemic corticoids and focal laser coagulation in the retinal tear (AU).

Toxocariasis ocular. A propósito de un caso / Ocular toxocariasis. Case report

RESUMEN Se presentó un caso clínico de un paciente de seis años de edad, con toxocariasis ocular. La manifestación clínica fue disminución de la agudeza visual monocular. El fondo de ojo izquierdo mostró un granuloma retiniano periférico, asociado a un desgarro retiniano perilesional. El examen oftalmológico confirmó el diagnóstico de Toxocara ocular. El paciente fue tratado posteriormente mediante corticoides sistémicos y fotocoagulación láser focal en el desgarro retiniano (AU).

ABSTRACT We present the clinical case of a male patient, aged 6 years, with ocular toxocariasis. The clinical manifestation was monocular visual acuity decrease. The left ocular fundus showed a peripheral retina granuloma, associated to a perilesional retinal tear. The ophthalmological examination confirmed the diagnosis of ocular Toxocara. After that the patient was treated using systemic corticoids and focal laser coagulation in the retinal tear (AU).

Long-term results of repeated anti-vascular endothelial growth factor therapy in eyes with retinal pigment epithelial tears.

PURPOSE: To evaluate the long-term results of retinal pigment epithelium tears in eyes treated with repeated anti-vascular endothelial growth factor (VEGF) therapy. METHODS: Five patients with retinal pigment epithelial tears (without foveal center involvement) after anti-VEGF injection were studied retrospectively. Mean follow-up time was 52 months, with measurements of visual acuity and evaluation of macular findings by angiography and optical coherence tomography during this period. All eyes had a persistent submacular neovascular membrane 30 days after the tear. An anti-VEGF drug was reinjected until the membranes stopped leaking. RESULTS: The mean initial visual acuity immediately after the tear was 20/160, and the mean final visual acuity was 20/60. The number of anti-VEGF reinjections varied from two to eight during the follow-up period. Long-term optical coherence tomography analysis showed reduced fluid and remodeling of the torn retinal pigment epithelium. CONCLUSION: Long-term visual results with repeated anti-VEGF therapy are not as devastating as suggested previously. Visual acuity and metamorphopsia improve with time as long as the neovascular membrane is inactive. Optical coherence tomography changes in the macular area reflect the visual acuity improvement.

Optical coherence tomography evaluation of idiopathic macular hole treatment by gas-assisted posterior vitreous detachment.

PURPOSE: To report a series of patients with Stage II macular hole (MH) treated by gas-assisted posterior vitreous detachment (GAPVD). DESIGN: Interventional case series. METHODS: Six patients (six eyes) with Stage II MH were submitted to a 0.4 ml perfluoropropane (C(3)F(8)) intravitreal injection. Comprehensive ophthalmic examination including best-corrected visual acuity, fundus photography, and optical coherence tomography (OCT) was performed at baseline and one, three, and six months after the procedure. RESULTS: Preoperative OCT revealed Stage II MH in all cases. In five cases, improvement in visual acuity and closure of the macular hole on OCT was observed at one, three, and six months after GAPVD. In one case, although vitreofoveal traction was released, MH closure was not achieved; a full-thickness retinal defect persisted and final visual acuity was 20/100. CONCLUSION: GAPVD may be a viable alternative treatment for Stage II MH.

Uso do adesivo biológico de fibrina no tratamento do descolamento regmatogênico de retina experimental em coelhos: 1- estudo clínico / Use of fibrin biologic adhesive in the treatment of experimental rhegmatogenous retinal detachments in rabbits: 1- clinical study

As técnicas modernas de vitrectomia "pars plana" têm permitido uma alta taxa de sucesso na cirurgia do descolamento de retina regmatogênico; entretanto, em alguns casos, ainda se obtém resultados poucos satisfatórios , pela dificuldade de se manter todos os buracos retinianos permanentemente fechados. Esta estudo objetiva verificar, de modo longitudinal, controlado, randomizado e cego, as alteraçöes clínicas induzidas, pelo adesivo biológico de fibrina heterólogo, nos olhos de coelhos submetidos à facectomia e vitrectomia "pars plana", para a correçäo de deslocamentos regmatogênicos de retina experimentais. Utilizaram-se 40 olhos divididos em dois grupos de vinte. Nos olhos do grupo A (grupo controle), realizou-se um descolamento de retina regmatogênico com a rotura, localizando-se a 2 diâmetros papilares, inferiormente ao centro do raio medular sem injeçäo de adesivo. Os olhos do grupo B(grupo de experimentaçäo) foram submetidos a igual procedimento; sendo injetado o adesivo de fibrina, na quantidade de 0,2 mililitros, no espaço subretiniano, após troca fluido-gasosa. Os olhos de cada grupo foram distribuídos em 10 subgrupos de 4 olhos e sacrificados no 1§, 4§, 7§, 14§ e 30§ dias de pós-operatório. Estudaram-se os achados clínicos, nos olhos do grupo A e B. A observaçäo clínica revelou que näo houve diferença significativa entre os olhos do grupo controle e do grupo que recebeu o adesivo de fibrina quanto aos resultados obtidos pelos exames clínicos da conjuntiva, câmara anterior e cavidade vítrea. O exame da retina revelou que houve maior adesividade retiniana; ou seja, menor taxa de descolamento de retina nos olhos que receberam o adesivo de fibrina. (p=0,05)