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4.
PLoS Biol ; 22(5): e3002612, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38781246

RESUMO

Scientific advances due to conceptual or technological innovations can be revealed by examining how research topics have evolved. But such topical evolution is difficult to uncover and quantify because of the large body of literature and the need for expert knowledge in a wide range of areas in a field. Using plant biology as an example, we used machine learning and language models to classify plant science citations into topics representing interconnected, evolving subfields. The changes in prevalence of topical records over the last 50 years reflect shifts in major research trends and recent radiation of new topics, as well as turnover of model species and vastly different plant science research trajectories among countries. Our approaches readily summarize the topical diversity and evolution of a scientific field with hundreds of thousands of relevant papers, and they can be applied broadly to other fields.


Assuntos
Plantas , Pesquisa/tendências , Aprendizado de Máquina , Botânica/tendências , Botânica/métodos
5.
An Acad Bras Cienc ; 96(1): e20230218, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38808812

RESUMO

Latin American and the Caribbean regions (LAC) harbor one of the most biodiverse areas of the world, the Neotropics. True bugs (Hemiptera: Heteroptera) are a diverse lineage of insects, with more than 45,000 species, particularly speciose in the Neotropical region. True bugs are fundamental in the dynamics of natural and modified ecosystems, with several species critical to agriculture and public health. We compiled Heteroptera research in LAC from 1998-2022 using bibliographic databases. Productivity, collaborative networks, and the main topics studied were analyzed. A total of 1,651 Heteroptera studies from LAC were found, with continuous growth being 2021 the most prolific. Four categories (Taxonomy of extant species, Faunistic inventories and new records, Pest species biology, and Community ecology) represent most of the published research. About 60 percent of the records evaluated correspond to five families (Pentatomidae, Reduviidae, Coreidae, Miridae, and Rhyparochromidae). We emphasize the need to keep working on Heteroptera taxonomy because it will allow further advances in other areas such as phylogenetic analyses, biogeography, ecology, and natural history, among others. The results of our analyses characterize the current state of heteropterology in the region, establishing a baseline for future studies and efforts to broaden the knowledge of the group.


Assuntos
Heterópteros , América Latina , Animais , Região do Caribe , Heterópteros/classificação , Pesquisa/tendências , Pesquisa/classificação , Bibliometria
8.
Fam Syst Health ; 42(1): 130-132, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38647495

RESUMO

Reviews the book, Handbook of Positive Youth Development: Advancing Research, Policy, and Practice in Global Contexts edited by Radosveta Dimitrova and Nora Wiium (2021). This volume deals with both the applications and interventions of positive youth development (PYD) in the context of families and other systems in global contexts. Additionally, it advances empirical and theoretical knowledge in PYD, refinement of methodological issues, and measurement and integration of PYD-related knowledge with policy, research, and practice. This book will interest a broad spectrum of readers, including social scientists, students, professionals, policymakers, and practitioners from various disciplines. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Desenvolvimento do Adolescente , Humanos , Adolescente , Pesquisa/tendências
11.
Bioinspir Biomim ; 19(4)2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38631363

RESUMO

This paper presents a bibliometrics analysis aimed at discerning global trends in research on 'biomimetics', 'biomimicry', 'bionics', and 'bio-inspired' concepts within civil engineering, using the Scopus database. This database facilitates the assessment of interrelationships and impacts of these concepts within the civil engineering domain. The findings demonstrate a consistent growth in publications related to these areas, indicative of increasing interest and impact within the civil engineering community. Influential authors and institutions have emerged, making significant contributions to the field. The United States, Germany, and the United Kingdom are recognised as leaders in research on these concepts in civil engineering. Notably, emerging countries such as China and India have also made considerable contributions. The integration of design principles inspired by nature into civil engineering holds the potential to drive sustainable and innovative solutions for various engineering challenges. The conducted bibliometrics analysis grants perspective on the current state of scientific research on biomimetics, biomimicry, bionics, and bio-inspired concepts in the civil engineering domain, offering data to predict the evolution of each concept in the coming years. Based on the findings of this research, 'biomimetics' replicates biological substances, 'biomimicry' directly imitates designs, and 'bionics' mimics biological functions, while 'bio-inspired' concepts offer innovative ideas beyond direct imitation. Each term incorporates distinct strategies, applications, and historical contexts, shaping innovation across the field of civil engineering.


Assuntos
Bibliometria , Biomimética , Biônica , Biônica/tendências , Engenharia , Bases de Dados Factuais , Pesquisa/tendências
12.
RNA ; 30(5): 530-536, 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38531650

RESUMO

Pseudouridine is an abundant mRNA modification found in diverse organisms ranging from bacteria and viruses to multicellular plants and humans. New developments in pseudouridine profiling provide quantitative tools to map mRNA pseudouridylation sites. Sparse biochemical studies establish the potential for mRNA pseudouridylation to affect most stages of the mRNA life cycle from birth to death. This recent progress sets the stage for deeper investigations into the molecular and cellular functions of specific mRNA pseudouridines, including in disease.


Assuntos
RNA Mensageiro , Pesquisa , RNA Mensageiro/química , RNA Mensageiro/metabolismo , Transferases Intramoleculares/metabolismo , Transcrição Gênica , Precursores de RNA/química , Precursores de RNA/metabolismo , Proteínas de Ligação a RNA/metabolismo , Biossíntese de Proteínas , Ligação Proteica , Humanos , Animais , Pesquisa/tendências
18.
Biochem Med (Zagreb) ; 34(1): 010502, 2024 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-38125621

RESUMO

YKL-40 or Chitinase-3-Like Protein 1 (CHI3L1) is a highly conserved glycoprotein that binds heparin and chitin in a non-enzymatic manner. It is a member of the chitinase protein family 18, subfamily A, and unlike true chitinases, YKL-40 is a chitinase-like protein without enzymatic activity for chitin. Although its accurate function is yet unknown, the pattern of its expression in the normal and disease states suggests its possible engagement in apoptosis, inflammation and remodeling or degradation of the extracellular matrix. During an inflammatory response, YKL-40 is involved in a complicated interaction between host and bacteria, both promoting and attenuating immune response and potentially being served as an autoantigen in a vicious circle of autoimmunity. Based on its pathophysiology and mechanism of action, the aim of this review was to summarize research on the growing role of YKL-40 as a persuasive biomarker for inflammatory diseases' early diagnosis, prediction and follow-up (e.g., cardiovascular, gastrointestinal, endocrinological, immunological, musculoskeletal, neurological, respiratory, urinary, infectious) with detailed structural and functional background of YKL-40.


Assuntos
Biomarcadores , Proteína 1 Semelhante à Quitinase-3 , Doença , Inflamação , Proteína 1 Semelhante à Quitinase-3/metabolismo , Inflamação/enzimologia , Inflamação/genética , Biomarcadores/sangue , Biomarcadores/metabolismo , Doença/genética , Pesquisa/tendências , Humanos , Animais , Diagnóstico Precoce
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