Assuntos
Poroceratose/diagnóstico , Adulto , Ainhum/congênito , Ainhum/diagnóstico , Ainhum/patologia , Braço , Biópsia , Constrição Patológica/congênito , Constrição Patológica/diagnóstico , Constrição Patológica/patologia , Diagnóstico Diferencial , Feminino , Humanos , Poroceratose/congênito , Poroceratose/patologiaRESUMO
Porokeratosis is a disorder of epidermal keratinization. A 27-year-old woman had papular, linearly arranged, hyperkeratotic lesions on the right foot since birth. Over the course of her life, the lesions progressed to involve the entire right leg and extended to the right side of her trunk, the right arm and chin. The clinical diagnosis of unilateral linear porokeratosis was confirmed by histopathology.
Assuntos
Poroceratose/congênito , Adulto , Biópsia , Feminino , Humanos , Poroceratose/diagnóstico , Poroceratose/patologia , Lesões Pré-Cancerosas/congênito , Lesões Pré-Cancerosas/diagnóstico , Lesões Pré-Cancerosas/patologia , Fatores de Risco , Pele/patologia , Neoplasias Cutâneas/congênito , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologiaRESUMO
Porokeratotic eccrine ostial and dermal duct nevus is a congenital hamartoma of possible eccrine origin with no malignant potential. It is usually localized at the extremity of a single limb, while wider systematized distribution has rarely been documented. A child with an unusually widespread nevus following Blaschko lines is reported. The disorder had a striking presentation in the form of a systematized linear epidermal nevus composed of multiple tiny filiform keratotic spines, which histologically corresponded to columns of porokeratosis. Serial histopathologic sections of a 4-mm punch biopsy specimen barely demonstrated an anatomic relationship between the porokeratotic columns and the underlying acrosyringeal duct. This report provides further evidence of porokeratotic eccrine ostial and dermal duct nevus being distributed along Blaschko lines, thus confirming it is a peculiar epidermal nevus due to a mosaic cutaneous condition.
Assuntos
Nevo Intradérmico/patologia , Poroceratose/patologia , Neoplasias Cutâneas/patologia , Feminino , Humanos , Lactente , Nevo Intradérmico/congênito , Poroceratose/congênito , Neoplasias Cutâneas/congênito , Glândulas SudoríparasRESUMO
We report a unique case of congenital linear porokeratosis with exclusive facial involvement in a 27-year-old Chinese man. No other family member was affected. To our knowledge, this is the first report in the English literature of congenital linear porokeratosis confined to the face.
Assuntos
Dermatoses Faciais/congênito , Poroceratose/congênito , Adulto , Biópsia , Dermatoses Faciais/patologia , Humanos , Masculino , Poroceratose/patologiaAssuntos
Poroceratose/congênito , Poroceratose/patologia , Administração Tópica , Adolescente , Biópsia por Agulha , Feminino , Seguimentos , Dermatoses da Mão/congênito , Dermatoses da Mão/tratamento farmacológico , Dermatoses da Mão/patologia , Humanos , Imuno-Histoquímica , Ácido Láctico/uso terapêutico , Poroceratose/tratamento farmacológico , Medição de Risco , Índice de Gravidade de Doença , Resultado do TratamentoAssuntos
Poroceratose/congênito , Feminino , Humanos , Lactente , Poroceratose/patologia , Pele/patologia , Coxa da PernaRESUMO
Porokeratosis is a genodermatosis characterized by abnormal epidermal keratinization with the histologic finding of cornoid lamella. To date, five clinical variants have been identified. However, the coexistence of these variants in a single patient has been described only rarely. We report a 5-year-old girl with the simultaneous occurrence of porokeratotic lesions in linear and disseminated patterns. Linear lesions were detected at birth and the disseminated lesions developed at the age of 3 years. Histologically the lesions had cornoid lamella, which is typical of this condition.
Assuntos
Poroceratose/patologia , Pele/patologia , Pré-Escolar , Feminino , Humanos , Poroceratose/congênitoRESUMO
The classic appearance of porokeratosis is characterized by a hyperkeratotic annular rim that expands peripherally, leaving an atrophic center. Linear porokeratosis is a variant with collections of such lesions arranged in a linear fashion, usually corresponding to a dermatome or Blaschko's lines. Ulcerations have rarely been reported in patients with porokeratosis. We report an unusual case of linear porokeratosis at birth, with erosions and ulcerations of the face and lower extremity, that eluded diagnosis for nearly a year. Porokeratosis should be considered in the differential diagnosis of erosions in the newborn period.
Assuntos
Poroceratose/congênito , Poroceratose/patologia , Humanos , Recém-Nascido , Masculino , Pele/patologiaRESUMO
Se comunica un caso de poroqueratosis zoniforme en cara posterior del miembro inferior izquierdo, presente desde el nacimiento en una sola gemela de 14 años. Se la supone provocada por una mutación somática en el ectodermo embrionario
Assuntos
Humanos , Feminino , Adolescente , Dermatoses da Perna/congênito , Poroceratose/congênitoRESUMO
Se comunica un caso de poroqueratosis zoniforme en cara posterior del miembro inferior izquierdo, presente desde el nacimiento en una sola gemela de 14 años. Se la supone provocada por una mutación somática en el ectodermo embrionario(AU)