RESUMO
Generalized occurrence of external root resorption in an adult patient is a rare finding. This case report describes external cervical root resorption extensively affecting the dentition that may be associated with the use and subsequent cessation of denosumab for the treatment of osteoporosis.
Assuntos
Conservadores da Densidade Óssea , Denosumab , Osteoporose , Reabsorção da Raiz , Adulto , Conservadores da Densidade Óssea/efeitos adversos , Denosumab/efeitos adversos , Humanos , Osteoporose/tratamento farmacológico , Reabsorção da Raiz/induzido quimicamente , Reabsorção de Dente/induzido quimicamenteRESUMO
Although the pathogenesis and etiology of external cervical resorption (ECR) are not well understood, several predisposing factors have been reported to potentially contribute toward the initiation of ECR. However, a potential link between systemic medication and ECR has not been reported. Bisphosphonates (BSPs) are 1 group of these medications (the amino-containing BSP), which are associated with an acute-phase response and the release of proinflammatory cytokines, which could be associated with the initiation of ECR. Therefore, a possible causal link between BSPs and ECR could be drawn.