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1.
J Plast Reconstr Aesthet Surg ; 74(10): 2479-2485, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33879412

RESUMO

BACKGROUND: Free flap complications are generally rare, but not negligible since they may exert paramount impact on both patients and care providers. The aim of the study was to identify risk factors for reexploration and assess predictors associated with increased salvage rates. METHODS: A retrospective cohort study was conducted for free flaps performed between 2006 and 2015. Patient demographics, indications and flap types were analyzed together with complications and time to reexploration. RESULTS: Among 547 consecutive free flaps, 11.5% required acute reexploration. Hematoma together with vascular compromise was the main cause (41.9%) for reexploration, followed by hematoma only (19.4%), venous (16.1%) and arterial (6.5%) thrombosis. Hematoma was associated with an increased risk for concomitant vascular complication (p < 0.02). The incidence of total and partial flap necrosis was 3.5% and 3.7% respectively. There was an overall 71.4% salvage rate. The median time from detection of a compromised flap to reexploration was 3.0 h. Significantly higher salvage rates were observed for cases reexplored within (82.4%) compared to after (57.1%) 3.0 h (OR 3.50 (95% CI 1.10 to 11.13, p = 0.034)). CONCLUSIONS: The current study highlights the importance of early intervention, including evacuation of hematomas that may lead to vascular compromise. Adequate monitoring of venous outflow was found necessary to improve flap salvage rates, whereas arterial complications were mainly related to persistent arterial injury in traumatized extremities with reduced salvage rates. Free flap surgery requires trained staff and immediate access to operating facilities to ensure high flap survival rates.


Assuntos
Retalhos de Tecido Biológico , Hematoma , Procedimentos de Cirurgia Plástica/efeitos adversos , Complicações Pós-Operatórias , Trombose , Intervenção Médica Precoce/métodos , Feminino , Retalhos de Tecido Biológico/efeitos adversos , Retalhos de Tecido Biológico/irrigação sanguínea , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/estatística & dados numéricos , Hematoma/etiologia , Hematoma/prevenção & controle , Hematoma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/patologia , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Fluxo Sanguíneo Regional , Reoperação/métodos , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Risco Ajustado/métodos , Fatores de Risco , Terapia de Salvação/métodos , Suécia/epidemiologia , Trombose/etiologia , Trombose/prevenção & controle , Trombose/cirurgia , Tempo para o Tratamento/estatística & dados numéricos
2.
J Plast Reconstr Aesthet Surg ; 74(6): 1279-1285, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33279430

RESUMO

The aim of the study is to evaluate costs of free flap surgery for head and neck (H & N) reconstructions using the time-driven activity-based costing (ABC) method and to compare them with the refund provided by the Italian National Health System (NHS) amounting to 11,891€. We retrospectively selected 29 consecutive patients underwent free flap reconstruction in 2013 at IRCCS Casa Sollievo della Sofferenza. Patients were divided into three groups: Group 1 (n = 10) included patients receiving radial forearm free flap (RFFF), Group 2 (n = 10) receiving anterolateral thigh (ALT) free flap, and Group 3 (n = 9) composed of patients having fibular free flap. For each patient, costs were calculated using the ABC and divided into instay, surgical, and services costs. We observed an overall mean total cost of 27,802.40€. The mean costs related to hospital stay were 9,800.70€. The mean costs for surgery were 13,097.60€ and amounted to 4,904.10€ for services. RFFF appears to be less costing (25,175.40€) compared with ALT (29,191.60€) and fibula free flap (29,040.20€). ABC is an appropriate method to determine actual costs of free flap surgery by correctly allocating the resources used. The Italian NHS tariff seems to be inadequate to cover the real cost of this type of surgery.


Assuntos
Custos e Análise de Custo , Retalhos de Tecido Biológico , Neoplasias de Cabeça e Pescoço , Procedimentos de Cirurgia Plástica , Custos e Análise de Custo/métodos , Custos e Análise de Custo/estatística & dados numéricos , Atenção à Saúde/economia , Feminino , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/economia , Neoplasias de Cabeça e Pescoço/economia , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/economia , Procedimentos de Cirurgia Plástica/métodos , Estudos Retrospectivos
3.
Injury ; 50 Suppl 5: S32-S39, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31711654

RESUMO

BACKGROUND: Goals of lower extremity microvascular reconstruction (LEMR) include the restoration of function, prevention of infection, and optimal cosmesis. Indications for LEMR include large defects that are not amenable to pedicled options, a large zone of injury, and large complex defects. The novice microsurgeon should first master a handful of free flaps to develop an armamentarium of options for addressing such defects. The scope of this review is to provide free flap options for LEMR in any of the thirds of the lower leg. After reading this article, the reader will understand variations, advantages, disadvantages, indications, and tips for raising each of these flaps. METHODS: Six most commonly used free flaps for LEMR are described in this paper, including the anterolateral thigh flap (ALT) and its variations, the radial forearm flap (RFFF), the lateral arm flap (LAF), the gracilis muscle flap, the rectus abdominis flap (RAF) and the latissimus dorsi flap and its variations. Indications, advantages, disadvantages and technique tips are discussed for each flap. Moreover, selection of the recipient vessels, preoperative management along with an algorithm are also provided. CONCLUSIONS: The ALT flap is a workhorse in covering defects of the leg, foot, and ankle. It's the flap of choice at our institution, especially given the number of traumatic wounds seen as a result of motor vehicles, all-terrain vehicles (ATV), lawnmowers, and gunshot wounds (GSW). At times, the lower extremity zone of injury requires a distant donor site. The RAF can also provide coverage for large soft tissue defects but donor-site morbidity remains its main drawback. The LAF and RFFF provide two pliable options, one that provides pliable soft tissue with minimal donor site morbidity and another that provides a long pedicle. The free gracilis flap is an excellent choice for crossing the ankle joint. Lastly, the free latissimus dorsi is indicated for large defects of the lower extremity independently of the location.


Assuntos
Retalhos de Tecido Biológico/classificação , Extremidade Inferior/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Lesões dos Tecidos Moles/cirurgia , Retalhos de Tecido Biológico/irrigação sanguínea , Músculo Grácil/transplante , Humanos , Microcirurgia/métodos , Cuidados Pós-Operatórios , Sítio Doador de Transplante
4.
Am J Otolaryngol ; 39(5): 518-521, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29884566

RESUMO

OBJECTIVE: Despite the resurgence in regional flap use, otolaryngology resident regional flap experience has been incompletely studied. We sought to characterize United States (US) otolaryngology resident exposure to, and perceptions of, supraclavicular flaps (SCFs), submental flaps (SMFs), and other regional flaps. METHODS: An online survey was disseminated every two weeks to 106 US otolaryngology residency program directors for distribution to residents within their programs between August and October 2016. 121 surveys were returned of which 106 were sufficiently completed and eligible for data analysis. RESULTS: Among residents with adequate responses, 52 were postgraduate year (PGY) 1-3 (junior) residents and 54 were PGY 4-7 (senior) residents. Senior residents participated in more pectoralis major flaps (mean: 8.1, 95%-CI: 6.5-9.8) compared to SCFs (mean: 1.5, 95%-CI: 1.0-2.0, p < 0.001) and SMFs (mean: 0.7; 95%-CI: 0.4-1.0, p < 0.001). Among senior residents exposed to SCFs, SMFs and pectoralis flaps, more individuals judged pectoralis major flaps as successful or very successful (96.2%, 95%-CI: 91.1-100%), compared to SCFs (64.3%, 95%-CI: 46.5-82.0%; p < 0.001) and SMFs (63.2%, 95%-CI: 41.5-84.8%; p = 0.001). CONCLUSIONS: Senior otolaryngology residents were exposed to fewer SCFs and SMFs compared to pectoralis major flaps. Resident perception that SCFs and SMFs were not as successful as pectoralis major flaps should be investigated further.


Assuntos
Competência Clínica , Educação de Pós-Graduação em Medicina/métodos , Retalhos de Tecido Biológico/transplante , Otolaringologia/educação , Procedimentos de Cirurgia Plástica/educação , Intervalos de Confiança , Feminino , Retalhos de Tecido Biológico/classificação , Rejeição de Enxerto , Sobrevivência de Enxerto , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Internato e Residência/métodos , Masculino , Retalho Miocutâneo/transplante , Avaliação das Necessidades , Inquéritos e Questionários , Estados Unidos
5.
Head Neck ; 39(9): 1888-1893, 2017 09.
Artigo em Inglês | MEDLINE | ID: mdl-28675554

RESUMO

BACKGROUND: The osteocutaneous radial forearm free flap (RFFF) is a versatile flap primarily used to reconstruct composite defects involving the mandible. The purpose of this study was to describe our experience with this flap for nonmandible reconstruction. METHODS: All patients undergoing nonmandible osseous reconstruction with free-tissue transfer were reviewed. Patients with osteocutaneous RFFF reconstructions were evaluated. The retrospective review of all osteocutaneous RFFFs was performed from 1998 to 2014. RESULTS: One hundred forty-two nonmandible osseous reconstructions were performed. Twenty-five patients underwent nonmandible osteocutaneous RFFF reconstruction. Eleven patients failed previous nonmicrovascular reconstruction. Reconstruction was for defects of the: palatomaxillary complex (n = 15), orbitomaxillary complex (n = 4), nasomaxillary complex (n = 4), larynx (n = 1), and clavicle (n = 1). There were no flap compromises. Postoperative complications included: 2 partial intraoral dehiscences; 1 recipient-site infection; and 1 seroma. Eight reconstructions required secondary procedures to improve functional and/or cosmetic outcomes. CONCLUSION: The osteocutaneous RFFF is a robust flap that can be used to reconstruct composite defects involving bone and soft-tissue beyond the mandible.


Assuntos
Carcinoma de Células Escamosas/cirurgia , Retalhos de Tecido Biológico/transplante , Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Qualidade de Vida , Adulto , Idoso , Carcinoma de Células Escamosas/mortalidade , Carcinoma de Células Escamosas/patologia , Estudos de Coortes , Feminino , Antebraço/cirurgia , Retalhos de Tecido Biológico/classificação , Sobrevivência de Enxerto , Neoplasias de Cabeça e Pescoço/mortalidade , Neoplasias de Cabeça e Pescoço/patologia , Hospitais Universitários , Humanos , Masculino , Mandíbula , Pessoa de Meia-Idade , Oregon , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/cirurgia , Rádio (Anatomia)/cirurgia , Procedimentos de Cirurgia Plástica/efeitos adversos , Reoperação/métodos , Estudos Retrospectivos , Medição de Risco , Análise de Sobrevida
6.
J Plast Reconstr Aesthet Surg ; 68(11): 1556-67, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26323993

RESUMO

Complex defects present structural and functional challenges to reconstructive surgeons. When compared to multiple free flaps or staged reconstruction, the use of chimeric flaps to reconstruct such defects have many advantages such as reduced number of operative procedures and donor site morbidity as well as preservation of recipient vessels. With increased popularity of perforator flaps, chimeric flaps' harvest and design has benefited from 'perforator concept' towards more versatile and better reconstruction solutions. This article discusses perforator based chimeric flaps and presents a practice based classification system that incorporates the perforator flap concept into "Perforator Chimerism". The authors analyzed a variety of chimeric patterns used in 31 consecutive cases to present illustrative case series and their new classification system. Accordingly, chimeric flaps are classified into four types. Type I: Classical Chimerism, Type II: Anastomotic Chimerism, Type III: Perforator Chimerism and Type IV Mixed Chimerism. Types I on specific source vessel anatomy whilst Type II requires microvascular anastomosis to create the chimeric reconstructive solution. Type III chimeric flaps utilizes the perforator concept to raise two components of tissues without microvascular anastomosis between them. Type IV chimeric flaps are mixed type flaps comprising any combination of Types I to III. Incorporation of the perforator concept in planning and designing chimeric flaps has allowed safe, effective and aesthetically superior reconstruction of complex defects. The new classification system aids reconstructive surgeons and trainees to understand chimeric flaps design, facilitating effective incorporation of this important reconstructive technique into the armamentarium of the reconstruction toolbox.


Assuntos
Retalhos de Tecido Biológico/classificação , Microcirurgia/métodos , Retalho Perfurante/classificação , Procedimentos de Cirurgia Plástica/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Anastomose Cirúrgica/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
7.
Cir. plást. ibero-latinoam ; 41(2): 117-126, abr.-jun. 2015. ilus, tab, graf
Artigo em Espanhol | IBECS | ID: ibc-142103

RESUMO

La transferencia de colgajos libres es una herramienta fundamental dentro del arsenal reconstructivo para el tratamiento quirúrgico del gran quemado. Durante años ha existido controversia sobre la influencia del momento de la cirugía sobre la tasa de complicaciones, así como el alto riesgo de complicaciones al realizar reconstrucciones con colgajos libres en pacientes quemados. Diseñamos un estudio retrospectivo de las reconstrucciones quirúrgicas mediante colgajos libres realizadas en nuestra Unidad de Quemados del Hospital Universitari y Politecnic La Fe, de Valencia (España) en el periodo comprendido entre 2001 y 2013, recogiendo todos los datos relativos al paciente, a la lesión, al procedimiento reconstructivo, a los resultados y relacionando todo ello con el momento en el cual se realizó la cirugía. Para el análisis de los datos y asociaciones entre distintas variables usamos tablas de contingencia y aplicamos el test de independencia de Chi-cuadrado. Exponemos además 2 casos clínicos representativos de la cirugía reconstructiva practicada en pacientes quemados. Recogimos en total datos de 21 procedimientos de reconstrucción mediante colgajo libre en pacientes quemados. En ninguno se realizó reconstrucción primaria inmediata (en los primeros 5 días), mientras que la reconstrucción primaria temprana (entre el día 5 y el 21) se realizó en el 28,57% de los casos, la primaria intermedia (entre el día 21 y las 6 semanas) en el 28,57%, la secundaria (más de 6 semanas) en el 9,5%, y la cirugía de secuelas en el 33,33% de los casos. Las tasas de complicaciones mayores y menores fueron respectivamente 19,05% y 9,5%. El 50% de complicaciones mayores ocurrieron en el periodo de reconstrucción primaria temprana, mientras que no registramos ninguna en el periodo primario intermedio. El resto de complicaciones se repartió a partes iguales entre el periodo secundario y la cirugía de secuelas (ambas con el 25%). No encontramos asociación estadísticamente significativa entre las variables en ninguna de las comparaciones realizadas. En conclusión, creemos que la reconstrucción mediante colgajos libres en pacientes quemados presenta un riesgo más elevado de complicaciones mayores cuando se realiza en el periodo primario temprano (entre los días 5 y 21 tras la quemadura) (AU)


Free flap transfer is an essential tool within the reconstructive repertoire for the surgical treatment of major burn patients. For a long time there has been controversy about the influence of the timing over the complication rate, as well as the increased complication risk when we perform reconstruction by means of free flaps in burn patients. We designed a retrospective study about free flap reconstructions performed in our Burns Unit at the Hospital Universitari y Politecnic La Fe, Valencia (Spain), in the period from 2001 to 2013, collecting data related to the patient, the lesion, the reconstructive procedure, the results, and all this data related to timing. For the data analysis and associations between the different variables we used contingency tables and applied the Chi-square independence test. In addition we present 2 representative clinical reports about burn reconstructive surgery. Data from 21 reconstructive procedures with free flaps in burn patients were collected. Immediate primary reconstruction (in the first 5 days) is not performed in any patient, while early primary reconstruction (from day 5 to 21) was performed in 28,57% of cases; the intermediate primary reconstruction (from day 21 to 6th week) was performed in 28,57%, the secondary reconstruction (more than 6 weeks) in 9,5% and sequelae surgery in 33,33% of the cases. Major and minor complication rate were 19,05% and 9,5% respectively; 50% of major complications happened in early primary reconstruction period, whereas no complication is registered in intermediate primary period, the rest of complications are equally divided between secondary reconstruction period and sequelae surgery (both of them 25%). No statistically significant association between the variables is found in any of the comparisons performed. In conclusion, we think that reconstruction with free flaps applied to burn patients presents a higher major complication rate when performed in the early primary period (from day 5 to day 21 after the burn) (AU)


Assuntos
Feminino , Humanos , Masculino , Queimaduras/metabolismo , Queimaduras/patologia , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/transplante , Aloenxertos Compostos/anatomia & histologia , Aloenxertos Compostos/cirurgia , Aloenxertos Compostos/transplante , Protocolos Clínicos/classificação , Estudos Retrospectivos , Queimaduras/reabilitação , Queimaduras/cirurgia , Retalhos de Tecido Biológico/cirurgia , Retalhos de Tecido Biológico , Aloenxertos Compostos/citologia , Aloenxertos Compostos/patologia , Protocolos Clínicos/normas , Espanha/etnologia , Estudos de Avaliação como Assunto
8.
Cir. plást. ibero-latinoam ; 41(2): 155-162, abr.-jun. 2015. ilus
Artigo em Espanhol | IBECS | ID: ibc-142108

RESUMO

La preservación del nivel de amputación tanto de la extremidad superior como de la inferior, puede mejorar la función residual y el proceso de rehabilitación protésica de la misma. Ambas van a estar condicionadas por la longitud restante de la extremidad, la presencia o no de articulaciones operativas y la calidad de la cobertura del muñón. Presentamos 2 casos de amputaciones. El primero es un caso agudo de amputación traumática de extremidad superior a la altura del tercio proximal de antebrazo, que asocia avulsión cutánea circular desde el tercio medio del brazo y con articulación de codo conservada. El segundo, es la secuela de una amputación infracondílea de extremidad inferior por osteosarcoma que presenta fístulas cutáneas con drenaje supurativo por osteomielitis en el muñón tibial. En ambos pacientes realizamos cobertura con colgajo anterolateral de muslo anastomosado a la arteria radial en el caso de la extremidad superior, y a la arteria genicular descendente en la extremidad inferior. En los dos casos el postoperatorio transcurrió sin complicaciones, logrando preservar las articulaciones del codo y de la rodilla respectivamente, así como la posterior rehabilitación protésica. Consideramos que el colgajo anterolateral del muslo permite aportar tejido de buena calidad como cobertura del muñón de amputación. Dadas las características del tejido aportado y su volumen, es idóneo tanto para cobertura de defectos agudos como de déficits de almohadillado en casos crónicos (AU)


Sometimes, the severity of the trauma or the existence of a cancer force to amputate a limb. The prosthetic rehabilitation process and residual function will be influenced by the remaining length of the limb, the presence or absence of functional joints and the quality of the coverage of the stump. Two cases of amputations are shown. The former is an acute traumatic upper limb amputation at the level of the proximal third of forearm with skin avulsion from the middle third of the arm and the elbow joint preserved. The second case is the sequelae of an amputation below the knee due to lower extremity osteosarcoma, which was referred with suppurative draining cutaneous fistulas as a consequence of an osteomyelitis of the femur in the stump. In both patients the stumps were covered with anterolateral thigh flap anastomosed over the radial artery in the case of the upper extremity, and over the descending genicular artery in the lower extremity. In both cases the postoperative course was uneventful, preserving the elbow and knee respectively and allowing the subsequent prosthetic rehabilitation. We consider that anterolateral thigh flap is a suitable option for the treatment of the amputation stump. Given the characteristics of the tissue and volume provided by this flap, it is appropriate for coverage of acute defects and for padding deficits in chronic cases (AU)


Assuntos
Humanos , Masculino , Prótese Articular/psicologia , Prótese Articular , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/patologia , Amputação Cirúrgica/métodos , Amputação Cirúrgica/reabilitação , Cotos de Amputação/lesões , Cotos de Amputação/fisiopatologia , Osteomielite/metabolismo , Osteomielite/patologia , Prótese Articular/provisão & distribuição , Prótese Articular/normas , Retalhos de Tecido Biológico/cirurgia , Retalhos de Tecido Biológico/transplante , Amputação Cirúrgica/psicologia , Amputação Cirúrgica/normas , Cotos de Amputação/anatomia & histologia , Cotos de Amputação/cirurgia , Osteomielite/psicologia , Osteomielite/cirurgia
9.
Cir. plást. ibero-latinoam ; 41(2): 163-168, abr.-jun. 2015. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-142109

RESUMO

El colgajo anterolateral de muslo descrito por Song y col. en 1984 es conocido en microcirugía por su versatilidad para la cobertura de defectos de tejidos. Su uso como colgajo pediculado, no tan ampliamente difundido, constituye una alternativa para la reconstrucción de defectos en abdomen, periné, sacro y muslos. El presente artículo describe la experiencia del Grupo de Cirugía Plástica Oncológica del Instituto Nacional de Cancerología de Bogotá, D.C. (Colombia) en la reconstrucción de defectos oncológicos de tejidos blandos con el colgajo pediculado anterolateral de muslo. Presentamos 10 pacientes tratados en 17 meses en los que, tras resección tumoral, se practicó reconstrucción quirúrgica con esta técnica. En todos ellos logramos una cobertura adecuada y estable de los defectos. Describimos la técnica quirúrgica empleada y las complicaciones recogidas en esta serie (AU)


The anterolateral thigh flap, described by Song et al. in 1984, is known for his versatility in microsurgery for reconstruction of soft tissue defects. Its use as a pedicled flap, not so widely popularized, is an alternative for the reconstruction of defects of the abdomen, perineum, sacrum and thighs. This paper presents the experience of the Oncologic Plastic Surgery Group of the Instituto Nacional de Cancerología from Bogota, D.C., Colombia, in the reconstruction of oncologic soft tissue defects using the pedicled anterolateral thigh flap. We present 10 patients treated over a 17 month period that were reconstructed using this technique after undorgone tumoral resection. All patients had an adequate and stable wound closure. We describe the surgical technique and complications related in this series (AU)


Assuntos
Feminino , Humanos , Masculino , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/patologia , Coxa da Perna/anormalidades , Coxa da Perna/lesões , Oncologia/métodos , Abdome/patologia , Períneo/lesões , Anastomose Cirúrgica/métodos , Retalhos de Tecido Biológico/cirurgia , Retalhos de Tecido Biológico/transplante , Coxa da Perna/patologia , Coxa da Perna/fisiologia , Oncologia/legislação & jurisprudência , Abdome/anormalidades , Períneo/fisiologia , Anastomose Cirúrgica/reabilitação , Colômbia/etnologia
10.
J Oral Maxillofac Surg ; 72(9): 1832-40, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24768422

RESUMO

PURPOSE: There are few studies analyzing the long-term clinical effects related to increasing the size of head and neck free tissue reconstructions. The purpose of this study was to compare long-term clinical outcomes of patients undergoing very large area (≥200 cm(2)) and large area (100 to 199 cm(2)) free tissue reconstructions of head and neck defects. PATIENTS AND METHODS: Institutional review board approval was obtained before conducting this retrospective cohort study at the authors' university-based tertiary care hospitals. The authors analyzed the charts of consecutive patients with free flaps of at least 100 cm(2) treated from July 2000 to December 2011. Very large area flaps were arbitrarily defined as larger than 200 cm(2). Intraoperative variables, flap success rates, overall survival, and total hospital and intensive care unit (ICU) stays for the 2 groups were analyzed. Fisher exact tests or χ(2) tests were used for categorical variables and Student t tests were used for continuous variables. Log-rank tests were conducted to investigate whether overall survival was significantly different between the 2 groups. Statistical significance was defined as a P value less than .05. RESULTS: The charts of 121 consecutive patients were analyzed. Thirty-eight patients (31%) had very large area flaps (277.1 ± 79.4 cm(2); range, 200 to 576 cm(2)) and 83 patients (69%) had large area flaps (140.1 ± 25.5 cm(2)). There was no difference between flap groups in presenting T4 stage disease (P = .448). Ninety-eight percent of the very large area flaps and 93% of the large area flaps survived. Total hospital stays for the very large area and large area flap groups were 12.8 ± 8.2 and 12.3 ± 8.3 days, respectively (P = not significant). In contrast, ICU stays were increased for the very large area flap group at 7.1 ± 7.5 versus 4.0 ± 4.0 days for the large area flap group (P = .022). The overall median patient survival for the very large area flap group was 7.6 months (95% confidence interval, 5.7-10.0) and that for the large area flap group was 8.4 months (95% confidence interval, 5.4-12.9; P = .376). CONCLUSION: Performing very large area flaps for head and neck reconstruction did not negatively affect clinical outcome. Comparable success rates, total hospital stays, and overall survival can be safely achieved in this difficult patient population. More studies need to be conducted on resource usage.


Assuntos
Retalhos de Tecido Biológico/classificação , Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Transplante Ósseo/métodos , Carcinoma de Células Escamosas/cirurgia , Criança , Estudos de Coortes , Cuidados Críticos/estatística & dados numéricos , Feminino , Seguimentos , Retalhos de Tecido Biológico/transplante , Sobrevivência de Enxerto , Hospitalização/estatística & dados numéricos , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Retalho Miocutâneo/classificação , Retalho Miocutâneo/transplante , Estadiamento de Neoplasias , Estudos Retrospectivos , Transplante de Pele/classificação , Taxa de Sobrevida , Resultado do Tratamento , Adulto Jovem
11.
Plast Reconstr Surg ; 133(6): 1315-1325, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24569421

RESUMO

BACKGROUND: The free transverse upper gracilis flap is well described for breast reconstruction and is the authors' second choice. Medial thigh soft tissue creates a durable, pliable, aesthetic breast; however, it has been criticized for modest volume and short pedicle. This demands frequent use of bilateral flaps for unilateral reconstructions, sacrifice of thoracodorsal vessels, and/or use of vein grafts. The authors have overcome these issues by modifying their microvascular techniques. METHODS: The authors describe several maneuvers that they have introduced, including excision and replacement of costal cartilage, using nontraditional internal mammary arterial anastomoses, and using adductor branches for flap-to-flap anastomoses to allow double flap reconstructions. The authors describe their case series of 30 transverse upper gracilis flaps to reconstruct 20 breasts in 18 patients. RESULTS: All flaps have survived. Seventy-five percent of the reconstructions were unilateral, although of these, 67 percent used two flaps to reconstruct one breast. The mean reconstructed breast was 360.9 g. Of 10 breasts reconstructed with double flaps, six used available adductor branches, whereas the others used internal mammary perforators, end-to-side anastomoses, or retrograde arterial flow. To complement this clinical approach, an anatomical study of the branching patterns from the gracilis pedicle has been carried out on 33 cadaveric specimens. CONCLUSIONS: The authors' study has allowed a new classification system to be defined and demonstrates suitable branching patterns to allow flap-to-flap anastomoses in 75 percent of patients; in those 25 percent where this is not possible, alternative strategies for double flaps can be sought and have been used successfully in our clinical series. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.


Assuntos
Retalhos de Tecido Biológico , Mamoplastia/métodos , Adulto , Idoso , Algoritmos , Anastomose Cirúrgica , Feminino , Retalhos de Tecido Biológico/classificação , Humanos , Masculino , Pessoa de Meia-Idade
12.
J Oral Maxillofac Surg ; 72(6): 1197-202, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24485977

RESUMO

The osseocutaneous fibula free flap is commonly used in mandibular reconstruction. Clinically important anatomic variants of the donor vessels have been reported. The authors describe a rare variant encountered while raising an osseocutaneous fibula flap. The fibula was supplied by the peroneal vessels and the overlying skin paddle was supplied by musculocutaneous perforators arising from the posterior tibial vessels. By raising 2 separate free flaps and configuring them in microvascular series with the fibula acting as a flow-through flap, the reconstruction was successful. Although the anatomic variant has been described, the authors' approach to it has not. The benefits of this method over other options include preservation of a skin paddle for monitoring and watertight oral closure and a long pedicle to the skin paddle permitting a wide arc of movement. The authors suggest a modification to the existing classification of perforators to the lateral leg skin to guide intraoperative decision making.


Assuntos
Variação Anatômica , Transplante Ósseo/classificação , Fíbula/irrigação sanguínea , Retalhos de Tecido Biológico/irrigação sanguínea , Retalho Perfurante/irrigação sanguínea , Transplante de Pele/classificação , Anastomose Cirúrgica/métodos , Carcinoma de Células Escamosas/cirurgia , Fáscia/transplante , Fíbula/transplante , Retalhos de Tecido Biológico/classificação , Humanos , Masculino , Osteotomia Mandibular/métodos , Reconstrução Mandibular/métodos , Pessoa de Meia-Idade , Soalho Bucal/cirurgia , Neoplasias Bucais/cirurgia , Retalho Perfurante/classificação , Pele/irrigação sanguínea , Artérias da Tíbia/anatomia & histologia
13.
J Oral Maxillofac Surg ; 72(1): 178-85, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23850041

RESUMO

PURPOSE: To investigate gender and other possible factors affecting the frequency and severity of postoperative complications in head and neck cancer free flap reconstruction. MATERIALS AND METHODS: A prospective longitudinal cohort study was conducted at the Greek Anticancer Institute, St. Savvas Hospital in head and neck cancer free flap reconstruction concerning postoperative complications. We documented the patients' demographic characteristics, social habits, and perioperative factors (ie, duration of general anesthesia), reconstructive techniques, neoadjuvant radiotherapy, and physical status. Initially, univariate statistical analysis was performed to confirm which predictor variables might influence the presence and severity of complications. Next, multivariate statistical analysis was performed using logistical regression and including the factors that were statistically significant on univariate analysis. RESULTS: From 1999 to 2009, we assessed 95 patients who had undergone surgery for head and neck cancer. Of the 95 patients, 24 were women and 71 were men. The patient age range was 20 to 87 years (mean 52, median 55). A total of 55 complications occurred in 49 patients (51.57%). Of the 55 complications, 12 (12.63%) were of major severity, 21 (22.10%) of median severity, and 22 (23.15%) of low severity. The statistical analysis revealed that the factors associated with complications were preoperative radiotherapy, female gender, and operation time. The factors associated with severe complications were female gender and alcohol use. CONCLUSIONS: Multivariate analysis of the data revealed that the factor associated with an increased incidence of postoperative complications was preoperative radiotherapy. Moreover, the variable that remained statistically significant and correlated with an increased incidence and severity of free flap reconstruction complications was female gender. Identifying the etiology of these findings is an intriguing field for additional research.


Assuntos
Retalhos de Tecido Biológico/transplante , Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica , Complicações Pós-Operatórias , Adulto , Idoso , Idoso de 80 Anos ou mais , Consumo de Bebidas Alcoólicas/efeitos adversos , Anestesia Geral/classificação , Carcinoma de Células Escamosas/radioterapia , Carcinoma de Células Escamosas/cirurgia , Estudos de Coortes , Suscetibilidade a Doenças , Feminino , Seguimentos , Retalhos de Tecido Biológico/classificação , Neoplasias de Cabeça e Pescoço/radioterapia , Nível de Saúde , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Terapia Neoadjuvante , Duração da Cirurgia , Complicações Pós-Operatórias/classificação , Estudos Prospectivos , Radioterapia Adjuvante/efeitos adversos , Procedimentos de Cirurgia Plástica/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Fatores Sexuais , Fumar/efeitos adversos , Adulto Jovem
14.
J Craniomaxillofac Surg ; 42(1): 79-83, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23522831

RESUMO

The reconstruction of hard and soft tissue defects, mainly after ablative oncologic surgery in the head and neck area, is an evolving field. The use of free flaps for reconstruction of the head and neck is considered to be the surgical standard. In our analysis of more than 1000 free flaps we give an overview of the development of the use of different types of free tissue transfer to the head and neck area over the last 25 years. We show that the evolving field of head and neck reconstruction raises new possibilities with new types of flaps, whereas other types of flaps disappear in the everyday clinical use. The spectrum of reconstruction possibilities broadens with the number of different flap types available to the head and neck surgeon.


Assuntos
Retalhos de Tecido Biológico/transplante , Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Transplante Ósseo/métodos , Retalhos de Tecido Biológico/classificação , Humanos , Microcirurgia/métodos , Músculo Esquelético/transplante , Estudos Retrospectivos , Retalhos Cirúrgicos/transplante
15.
J Craniofac Surg ; 24(6): 2091-7, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24220414

RESUMO

The oropharynx has a variety of functions, such as mastication, deglutition, articulation, taste, and airway protection. Because of its many roles, recent goals in head and neck reconstruction have focused on anatomic and functional reconstructions to minimize functional deficits. Since chemoradiation has earned a good reputation in the management of head and neck cancer, the manifestation of oropharyngeal defects has changed. Although we could not control the anatomic defects that were known to be related to the oropharyngeal functions, we hypothesized that optimizing the flap designs would be helpful for minimizing the functional deficits.Two hundred fifty cases of the head and neck reconstruction using free flaps were carried out between March 2006 and December 2010, where modified flap designs were applied. Among these, 37 tongue and 15 tonsillar reconstructions were analyzed for functional outcomes. The patients were of Asian ethnic background, and the average age was 52 years, including 38 males and 17 females. The average follow-up period was 20.5 months. Based on previous studies, the flap designs were categorized into type I, unilobe; type II, bilobe; type III, trilobe; type IV, quadrilobe; type V, additional lobe for lateral and posterior pharyngeal wall; and type VI, additional lobe for tongue base. The functional outcomes of both tongue and tonsillar reconstructions were investigated.To quantify the outcome in terms of swallowing and pronunciation, we analyzed the patients' function based on the 7-scale parameter. In terms of swallowing, the tongue reconstruction group scored 5.70 on average, whereas the tonsillar reconstruction group showed an average score of 4.53. With regard to speech intelligibility, the tongue reconstruction group revealed an average score of 5.67, whereas the tonsillar reconstruction group scored 5.46 on average.Our findings indicate that specification of the flap designs is helpful for minimizing the functional deficits in head and neck reconstructions.


Assuntos
Neoplasias Orofaríngeas/cirurgia , Orofaringe/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos/classificação , Adulto , Idoso , Deglutição/fisiologia , Fáscia/transplante , Feminino , Seguimentos , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/transplante , Gengiva/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Soalho Bucal/cirurgia , Retalho Miocutâneo/transplante , Terapia Neoadjuvante , Orofaringe/fisiopatologia , Palato Mole/cirurgia , Planejamento de Assistência ao Paciente , Transplante de Pele/métodos , Inteligibilidade da Fala/fisiologia , Retalhos Cirúrgicos/transplante , Neoplasias da Língua/cirurgia , Neoplasias Tonsilares/cirurgia , Resultado do Tratamento
16.
Br J Oral Maxillofac Surg ; 51(6): 514-9, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23399107

RESUMO

Several microvascular free flaps are available for reconstruction of the osseous components after resections for head and neck cancer. We have prospectively evaluated patients treated by bony microsurgical reconstruction to identify predictors of adverse outcomes for delayed wound healing and failure of free flaps. All patients from July 2007 to June 2011 who had reconstructions with microvascular fibular or iliac crest flaps immediately after resection of the tumour were evaluated. There were a total of 156 bony free flaps: 120 (77%) fibular and 36 (23%) iliac crest flaps. A total of 133 (85%) were successful. Delayed wound healing was more common with the iliac crest flap (p=0.01) at the intraoral site (p=0.04). Significantly more iliac crest free flaps failed (p=0.02). Anastomosis to the facial artery (p=0.05) and facial vein (p=0.04), and duration of overall operating time were associated with a significantly higher risk of failure of the flap. Patients with cancer of the head and neck who require microsurgical bony reconstruction are at increased risk of postoperative complications. Significantly more complications were found with the iliac crest flap, whereas the fibular flap was associated with a significantly longer operating time.


Assuntos
Transplante Ósseo/métodos , Retalhos de Tecido Biológico/transplante , Neoplasias de Cabeça e Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Anastomose Cirúrgica/métodos , Cuidados Críticos , Face/irrigação sanguínea , Feminino , Fíbula/cirurgia , Retalhos de Tecido Biológico/classificação , Sobrevivência de Enxerto , Hospitalização , Humanos , Ílio/cirurgia , Tempo de Internação , Masculino , Microcirurgia/métodos , Pessoa de Meia-Idade , Duração da Cirurgia , Osteorradionecrose/etiologia , Estudos Prospectivos , Reoperação , Fatores de Risco , Transplante de Pele/métodos , Deiscência da Ferida Operatória/etiologia , Infecção da Ferida Cirúrgica/etiologia , Sítio Doador de Transplante/cirurgia , Resultado do Tratamento , Cicatrização/fisiologia
17.
J Oral Maxillofac Surg ; 70(5): e371-7, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22538027

RESUMO

PURPOSE: Microvascular reconstruction of oncologic surgical and traumatic defects has been globally practiced by plastic and orthopedic surgical disciplines since the early 1970s. During the past 20 years, reconstructive techniques have been progressively incorporated into the purview of oral and maxillofacial and otolaryngology-head and neck surgeons, particularly those practicing in Europe, the United Kingdom, and China. There has also been a steady increase in the adoption of these techniques in North America, South America, and Japan. MATERIALS AND METHODS: We reviewed our experience (during a 5-year period) with microvascular reconstruction of postablative defects in the oral and maxillofacial region. To our knowledge, resection and neck dissection (or neck exploration in benign free tissue transfer); undertaken by an oral and maxillofacial surgeon), and free tissue transfer reconstruction (undertaken by otolaryngology head and neck and oral and maxillofacial surgeons) of ablative defects of the mouth, jaws, and face (managed within an Australian head and neck cancer multidisciplinary care team) have not been previously reported. RESULTS: The study cohort comprised 107 patients who underwent 109 microvascularly anastomosed free tissue transfers. Of the 107 patients, 79 were males and 38 were females. The median age was 62 years (range 15 to 87). The clinicodemographic analyses and the range of complications observed in this patient cohort are reported. The overall flap success rate in our study was 97%. CONCLUSIONS: The surgical outcomes of our study compare favorably with those previously reported.


Assuntos
Neoplasias Faciais/cirurgia , Neoplasias Maxilomandibulares/cirurgia , Neoplasias Bucais/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Anastomose Cirúrgica/métodos , Austrália , Transplante Ósseo/métodos , Carcinoma de Células Escamosas/cirurgia , Estudos de Coortes , Fáscia/transplante , Feminino , Retalhos de Tecido Biológico/irrigação sanguínea , Retalhos de Tecido Biológico/classificação , Humanos , Complicações Intraoperatórias , Masculino , Microcirurgia/métodos , Pessoa de Meia-Idade , Esvaziamento Cervical/métodos , Esvaziamento Cervical/estatística & dados numéricos , Complicações Pós-Operatórias , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Estudos Retrospectivos , Transplante de Pele/métodos , Trombose/etiologia , Resultado do Tratamento , Trombose Venosa/etiologia , Adulto Jovem
18.
J Oral Maxillofac Surg ; 70(7): 1692-8, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22079062

RESUMO

PURPOSE: To evaluate complications and success of mandibular reconstruction with free fibula flaps, iliac crest flaps, and forearm flaps with reconstruction plates and to evaluate dental rehabilitation after these reconstructions. PATIENTS AND METHODS: Eighty-three patients with segmental mandibular defects were included. Correlation analyses were used to determine the relationship between reconstruction type and clinical parameters with recipient-site complications and success. The dental rehabilitation was evaluated in successfully reconstructed survivors. RESULTS: Multivariate analyses showed significant correlations between flap type and success (P < .0001). Of the patients, 51 (61%) were alive 2 years after the reconstruction. Mandibular reconstruction with a free forearm flap and reconstruction plate was associated with higher complication rates at the recipient site and higher failure rates compared with reconstruction with free vascularized bone flaps. Of the 32 successfully reconstructed survivors, 14 (44%) had a complete dental rehabilitation, of which 10 had dental implants and 4 did not. Only 6 (29%) of the edentulous survivors ultimately had an implant-supported prosthesis. CONCLUSIONS: Reconstruction of the mandible with a free vascularized bone flap is superior to reconstruction with a free forearm flap with a reconstruction plate. Complete dental rehabilitation was reached in fewer than half of the surviving patients.


Assuntos
Implantação Dentária Endóssea , Retalhos de Tecido Biológico/classificação , Mandíbula/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Complicações Pós-Operatórias , Adulto , Idoso , Idoso de 80 Anos ou mais , Placas Ósseas , Transplante Ósseo/métodos , Carcinoma de Células Escamosas/reabilitação , Carcinoma de Células Escamosas/cirurgia , Implantes Dentários , Prótese Dentária Fixada por Implante , Feminino , Seguimentos , Sobrevivência de Enxerto , Humanos , Masculino , Traumatismos Mandibulares/reabilitação , Traumatismos Mandibulares/cirurgia , Pessoa de Meia-Idade , Neoplasias Bucais/reabilitação , Neoplasias Bucais/cirurgia , Osteotomia/métodos , Estudos Retrospectivos , Taxa de Sobrevida , Coleta de Tecidos e Órgãos/métodos , Resultado do Tratamento , Adulto Jovem
19.
Br J Oral Maxillofac Surg ; 50(1): 25-9, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21190760

RESUMO

Thin and pliable flaps with long, high calibre pedicles are ideally suited to lining the inside of the mouth. The radial forearm free flap has been our flap of choice until now, but we are unhappy with its potential for complications at the donor site. As an alternative, 30 patients have been treated in our unit with peroneal perforator flaps. Magnetic resonance (MR) angiography is necessary preoperatively to identify major perforating vessels. Flaps were raised using a lateral approach after the position of the most suitable perforator had been marked on the skin. The skin flaps were outlined in the proximal half of the lower leg with a maximum width of 5 cm to allow for direct closure of the wound. Five patients (of the original 35) were excluded after the results of MR angiography were known. All perforators identified on MR angiography could be exposed in the proximal half of the lower leg and most had a septocutaneous course. Reconstructions were in the floor of the mouth (n=16), tongue (n=11), and buccal mucosa (n=3). All but one flap survived with satisfactory functional results. The donor site morbidity was low. With the aid of MR angiography the peroneal perforator flap is a safe option for intraoral reconstruction. For small and medium sized defects we think that this flap is a good alternative to others, particularly if direct closure at an inconspicuous donor site is desired.


Assuntos
Retalhos de Tecido Biológico/irrigação sanguínea , Boca/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Idoso , Anastomose Cirúrgica , Carcinoma de Células Escamosas/cirurgia , Bochecha/cirurgia , Feminino , Fíbula , Retalhos de Tecido Biológico/classificação , Sobrevivência de Enxerto , Humanos , Processamento de Imagem Assistida por Computador/métodos , Perna (Membro)/irrigação sanguínea , Angiografia por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Soalho Bucal/cirurgia , Mucosa Bucal/cirurgia , Neoplasias Bucais/cirurgia , Músculo Esquelético/transplante , Satisfação do Paciente , Complicações Pós-Operatórias , Transplante de Pele/métodos , Transplante de Pele/patologia , Coleta de Tecidos e Órgãos/métodos , Língua/cirurgia
20.
Br J Oral Maxillofac Surg ; 50(1): 85-7, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21377775

RESUMO

Since the introduction of "Payment by Results", departmental income has been linked to clinical activity, and the coding of theatre activity (Office of Population, Censuses and Surveys Classification of Surgical Operations and Procedures (4th revision), OPCS-4) must be accurate and timely. We assess the accuracy of OPCS-4 coding for patients having microvascular free tissue transfer for head and neck cancer, and evaluate the impact it has on departmental income. Codes for a consecutive cohort of patients were checked to identify inaccuracies and the tariffs were recalculated. Incorrect coding in 11/21 cases resulted in a financial loss of £77449.00 because reconstruction had not been recorded as F39.1, which would automatically place it in the maximum income group, CZ04. If funding is to be optimised surgeons must be cognisant of the importance to code procedures accurately with respect to financial reimbursement. Regular monitoring of coding is suggested, including that of coexisting morbidities.


Assuntos
Auditoria Clínica , Codificação Clínica/economia , Retalhos de Tecido Biológico/economia , Renda , Procedimentos Cirúrgicos Bucais/economia , Procedimentos de Cirurgia Plástica/economia , Centro Cirúrgico Hospitalar/economia , Codificação Clínica/normas , Estudos de Coortes , Retalhos de Tecido Biológico/classificação , Neoplasias de Cabeça e Pescoço/cirurgia , Preços Hospitalares , Humanos , Mecanismo de Reembolso/economia , Odontologia Estatal/economia , Reino Unido
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