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1.
J Oral Maxillofac Surg ; 82(2): 181-190, 2024 02.
Artigo em Inglês | MEDLINE | ID: mdl-37995761

RESUMO

BACKGROUND: Jaw deformity diagnosis requires objective tests. Current methods, like cephalometry, have limitations. However, recent studies have shown that machine learning can diagnose jaw deformities in two dimensions. Therefore, we hypothesized that a multilayer perceptron (MLP) could accurately diagnose jaw deformities in three dimensions (3D). PURPOSE: Examine the hypothesis by focusing on anomalous mandibular position. We aimed to: (1) create a machine learning model to diagnose mandibular retrognathism and prognathism; and (2) compare its performance with traditional cephalometric methods. STUDY DESIGN, SETTING, SAMPLE: An in-silico experiment on deidentified retrospective data. The study was conducted at the Houston Methodist Research Institute and Rensselaer Polytechnic Institute. Included were patient records with jaw deformities and preoperative 3D facial models. Patients with significant jaw asymmetry were excluded. PREDICTOR VARIABLES: The tests used to diagnose mandibular anteroposterior position are: (1) SNB angle; (2) facial angle; (3) mandibular unit length (MdUL); and (4) MLP model. MAIN OUTCOME VARIABLE: The resultant diagnoses: normal, prognathic, or retrognathic. COVARIATES: None. ANALYSES: A senior surgeon labeled the patients' mandibles as prognathic, normal, or retrognathic, creating a gold standard. Scientists at Rensselaer Polytechnic Institute developed an MLP model to diagnose mandibular prognathism and retrognathism using the 3D coordinates of 50 landmarks. The performance of the MLP model was compared with three traditional cephalometric measurements: (1) SNB, (2) facial angle, and (3) MdUL. The primary metric used to assess the performance was diagnostic accuracy. McNemar's exact test tested the difference between traditional cephalometric measurement and MLP. Cohen's Kappa measured inter-rater agreement between each method and the gold standard. RESULTS: The sample included 101 patients. The diagnostic accuracy of SNB, facial angle, MdUL, and MLP were 74.3, 74.3, 75.3, and 85.2%, respectively. McNemar's test shows that our MLP performs significantly better than the SNB (P = .027), facial angle (P = .019), and MdUL (P = .031). The agreement between the traditional cephalometric measurements and the surgeon's diagnosis was fair. In contrast, the agreement between the MLP and the surgeon was moderate. CONCLUSION AND RELEVANCE: The performance of the MLP is significantly better than that of the traditional cephalometric measurements.


Assuntos
Anormalidades Maxilomandibulares , Má Oclusão Classe III de Angle , Prognatismo , Retrognatismo , Humanos , Prognatismo/diagnóstico por imagem , Retrognatismo/diagnóstico por imagem , Estudos Retrospectivos , Mandíbula/diagnóstico por imagem , Mandíbula/anormalidades , Má Oclusão Classe III de Angle/cirurgia , Cefalometria/métodos
2.
Eur J Pediatr ; 182(12): 5501-5510, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37777602

RESUMO

Twin-block appliance had been advocated as a potential treatment option in paediatric obstructive sleep apnoea (OSA) due to their favourable effect in enhancing upper airway parameters and improving OSA symptoms. The aim of this study was to evaluate the effect of twin-block appliance therapy on upper airway parameters/dimensions and the apnoea-hypopnea indexes (AHIs) in OSA children with class II mandibular retrognathic skeletal malocclusion using cone-beam computed tomography. This prospective longitudinal study comprised 34 polysomnography-proven OSA growing children with class II mandibular retrognathic skeletal malocclusion between the ages of 8 and 12 years who had completed myofunctional twin-block therapy and matched corresponding controls. The upper airway was segmented into the nasopharynx, oropharynx, and hypopharynx, and the effect of twin-bock treatment on upper airway parameters/dimensions was assessed pre- and posttreatment using CBCT analysis, while a second standard overnight PSG was performed to determine changes in the AHI. At the nasopharynx level, minimal (nonsignificant) increases in all variables were observed within the twin-block group and between the groups (P > 0.05). At the level of the oropharynx, all variables increased significantly in the treatment group and between groups (P < 0.001), but these increases were nonsignificant in the control group. At the level of the hypopharynx, only the minimum cross-sectional area (MCA) increased significantly in the treatment group (P = 0.003). The change in MCA was also significant between the groups (P = 0.041). In addition, the upper airway length increased significantly in the twin-block group (P = 0.0154), and the AHI decreased by 74.8% (P < 0.001). CONCLUSION: Correction of class II mandibular retrognathic skeletal malocclusion with twin-block appliance resulted in a significant increase in upper airway volume, MCA, anteroposterior and lateral distances of the MCA at the level of the oropharynx, MCA at the level of the hypopharynx and upper airway length, and a significant decrease in AHI, but it had no effect on nasopharynx parameters. WHAT IS KNOWN: • CBCT imaging has been shown to be an effective and precise diagnostic tool for analyzing the upper airways and craniofacial structures. • Twin block appliance may be an effective treatment modality in children with OSA. WHAT IS NEW: • Minimal cross-sectional area of upper ways may be the most relevant potential parameter when explaining how the upper airway anatomy plays role of in the pathogenesis of pediatric OSA. • Twin block appliance induced favorable changes in upper airway morphology (oropharynx area mainly) and respiratory parameters in OSA children with class II malocclusion.


Assuntos
Má Oclusão Classe II de Angle , Má Oclusão , Retrognatismo , Apneia Obstrutiva do Sono , Tomografia Computadorizada de Feixe Cônico Espiral , Humanos , Criança , Retrognatismo/diagnóstico por imagem , Retrognatismo/terapia , Estudos Longitudinais , Estudos Prospectivos , Má Oclusão Classe II de Angle/complicações , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe II de Angle/terapia , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/diagnóstico por imagem , Apneia Obstrutiva do Sono/terapia , Cefalometria/métodos
3.
Int Orthod ; 21(3): 100782, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37295170

RESUMO

Date of birth>09/06/2004; sex: female. Pre-treatment documents>13years 4months old: 07/07/2017. Diagnosis>Skeletal class II with mandibular retrusion, normodivergent facial pattern; class II division 2. Treatment planning>bimaxillary buccal fixed appliance. Duration of active treatment>29months. Post-treatment documents>15years 6months; 20/12/2019. Post-retention documents>16years 7months old; 04/01/2021. Retention period>2years 9months and still continued.


Assuntos
Má Oclusão Classe II de Angle , Micrognatismo , Braquetes Ortodônticos , Ortodontia , Retrognatismo , Humanos , Feminino , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe II de Angle/terapia , Ortodontia Corretiva , Retrognatismo/diagnóstico por imagem , Retrognatismo/terapia , Cefalometria , Aparelhos Ortodônticos Fixos
4.
BMC Oral Health ; 22(1): 149, 2022 04 28.
Artigo em Inglês | MEDLINE | ID: mdl-35484618

RESUMO

BACKGROUND: Only a few studies have used 3D cone-beam computed tomography (CBCT) analysis to evaluate the positional and morphological characteristics of the temporomandibular joint (TMJ) in adults with skeletal Class II. No studies have focused on the case of skeletal Class II with mandibular retrognathism in different vertical skeletal patterns. As a result, this study aimed to evaluate and compare the position and morphology of TMJ in adults with skeletal Class II with mandibular retrognathism in different vertical skeletal patterns to the position and morphology of TMJ in the normal Chinese adult population in three dimensions. METHODS: This retrospective study analyzed CBCT images of 80 adult patients. Subjects with skeletal Class II with a normal sagittal position of the maxilla and mandibular retrognathism were classified according to the mandibular angle and facial height ratio into three groups of 20 subjects each: hypodivergent, normodivergent, and hyperdivergent groups, as well as a control group of 20 subjects. The following 3D measurements of TMJ were evaluated: (1) position, parameters, and inclination of the mandibular fossa; (2) position, parameters, and inclination of the mandibular condyle; (3) condyle centralization in their respective mandibular fossae; (4) anterior, posterior, superior, and medial joint spaces; and (5) 3D volumetric measurements of the TMJ spaces. Measurements were statistically analyzed by one-way ANOVA test, followed by Tukey's post hoc test. RESULTS: Significant differences were found in the hyperdivergent and hypodivergent groups compared with the normal group in the vertical and anteroposterior mandibular fossa position, vertical condylar inclination, and condylar width and length. The hyperdivergent group showed the significantly highest condylar inclination with the midsagittal plane; anterior and superior positioning of the condyle; smallest anterior, superior, and medial joint spaces; and largest volumetric total joint space relative to the two other groups. CONCLUSIONS: The condyle-fossa position and morphology differ with various vertical facial patterns in individuals with skeletal Class II mandibular retrognathism. These differences could be considered during TMD diagnosis and orthodontic treatment.


Assuntos
Má Oclusão , Retrognatismo , Adulto , Humanos , Côndilo Mandibular/anatomia & histologia , Côndilo Mandibular/diagnóstico por imagem , Retrognatismo/diagnóstico por imagem , Estudos Retrospectivos , Articulação Temporomandibular/diagnóstico por imagem
5.
J Craniofac Surg ; 33(2): 521-525, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34669681

RESUMO

ABSTRACT: This study aims to introduce a new sagittal cephalometric measurement, the sagittal G-triangle analysis, to accurately and reproducibly assess the sagittal jaw relationship. Sagittal G-triangle analysis, which consists of angles AXK and BXK, is based on an equilateral triangle (Bo-X-K) constructed using 5 cephalometric landmarks (Ba, Bo, Po, Or, and G). To test the diagnostic efficiency of this analysis, pretreatment cephalometric radiographs of 120 female and 120 male Chinese patients were randomly selected. For each enlisted subject, angles SNA and SNB as well as angles AXK and BXK were measured and recorded. On the basis of the SNA and SNB results, subjects were categorized into 6 groups: maxillary retrognathism, normal maxilla, maxillary prognathism, mandibular retrognathism, normal mandible, and mandibular prognathism. The diagnostic efficiency of angles AXK and BXK were evaluated using various statistical tests. A high correlation was detected between angles SNA and AXK as well as between angles SNB and BXK. Female patients with angle AXK between -2.255° and 2.860° and male patients with angle AXK between -2.615° and 2.120° were considered to have a normal maxilla position. Female patients with angle BXK between -2.61° and 2.93° and male patients with angle BXK between -2.275° and 0.610° were considered to have a normal mandible position. In conclusion, sagittal G-triangle analysis could be used as an alternative method for the evaluation of the sagittal position of the maxilla and mandible in cephalometric analysis.


Assuntos
Má Oclusão Classe III de Angle , Má Oclusão , Prognatismo , Retrognatismo , Cefalometria/métodos , Feminino , Humanos , Masculino , Mandíbula/diagnóstico por imagem , Maxila/diagnóstico por imagem , Retrognatismo/diagnóstico por imagem
6.
Orthod Craniofac Res ; 25(2): 212-218, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34365733

RESUMO

OBJECTIVE: To evaluate the acceptance of orthodontists, laypeople and the patient when progressive mandibular advancements are performed in class II subjects with mandibular retrognathism. SETTING AND SAMPLE: 3D images were obtained by an optical surface scanning of fifteen individuals (12 males and three females, mean age of 23 years and 8 months) with mandibular retrognathism in three mandibular positions: maximum intercuspation (MIC) and progressive mandibular advancement of 2 and 4 mm. METHODS: The images (n = 45) were evaluated through a scale by two groups of panellist, 20 orthodontists, 20 laypeople and by the patients themselves (n = 15). The participants evaluated and rated each video and give scores between 0 and 10, according to their perception of facial harmony. MANOVA for repeated measures was used for intra- and intergroup differences and to evaluate the patients' self-perception. RESULTS: Laypeople reported better face acceptance than orthodontists in MIC and progressive mandibular advancement of 2 and 4 mm (P < .0001). 80% of the patients evaluated their own face as pleasant in MIC. Around half of them did not note significant difference following mandibular advancement of 2 mm as compared with MIC and even two-third attributed lower scores when the mandible was advanced 4 mm. CONCLUSION: A high variability was observed among all groups of raters. Patient´s opinion should be taken into account when mandibular advancement of 4 mm or more is planned. This study suggests that a thorough discussion of facial changes resulting from mandibular advancement should be carried out among professionals, parents and patients.


Assuntos
Má Oclusão Classe II de Angle , Má Oclusão , Avanço Mandibular , Retrognatismo , Adulto , Cefalometria , Feminino , Humanos , Imageamento Tridimensional , Masculino , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe II de Angle/terapia , Mandíbula , Avanço Mandibular/métodos , Ortodontistas , Retrognatismo/diagnóstico por imagem , Adulto Jovem
7.
Stomatologiia (Mosk) ; 100(6): 99-107, 2021.
Artigo em Russo | MEDLINE | ID: mdl-34953197

RESUMO

This article describes a case report of the patient with mandibular retrognathia, class II malocclusion, constriction and deformation of dental arches and bimaxillary protrusion. Due to the patient's refuse to undergo the orthognathic surgery, after diagnostic, it was decided to carry out the orthodontic dentoalveolar compensation. The combined use of the functional fixed telescopic appliance (FFTA), bracket system and orthodontic miniscrews made it possible to effectively normalize the mandibular position, achieve orthognathic occlusion, eliminate bimaxillary protrusion and improve the face profile. This method significantly reduced invasiveness and time of orthodontic treatment.


Assuntos
Má Oclusão Classe II de Angle , Má Oclusão , Retrognatismo , Adulto , Cefalometria , Humanos , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe II de Angle/terapia , Mandíbula/cirurgia , Retrognatismo/diagnóstico por imagem , Retrognatismo/cirurgia
8.
Am J Med Genet A ; 185(1): 46-49, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33030227

RESUMO

Retrognathia (recessed chin) and prognathism (prominent chin) often present as signs of an underlying condition. Accurate clinical definitions are important. Yet their definitions were according to "clinical impression", or to seldom used X-ray criteria. We propose a statistical and anthropometric definition of retrognathia and prognathism based upon the ratio between the goniomaxillar length (distance between the gonion at the mandible angle and the subnasale and the goniomandibular length (distance between the mandible angle and the most anterior point of the bony chin). We assumed that an increase in the ratio indicates retrognathia and a decrease reflects prognathism. We conducted a prospective, observational, anthropometric study in 204 consecutive healthy term infants. Measurements took place on the second day of life, using sliding calipers. Mean ± SD of goniomandibular length (5.1 ± 0.3 cm), goniomaxillar length (5.4 ± 0.3 cm), were calculated. All measurements correlated significantly with gestational age, and with infant birthweight. The mean ± SD goniomaxillar length/goniomandibular length ratio was 1.06 ± 0.05. We defined a normal ratio as being within 2 SD of the mean, that is, between 0.96 and and 1.16. This ratio correlated with neither gestational age nor with birthweight. We conclude that the goniomaxillar length/goniomandibular length ratio can be calculated whenever retro - or prognathism is suspected. A ratio outside of the 95% confidence interval should help in making this diagnosis. An increase in this ratio beyond 2 SD above the mean (1.16) could be interpreted as retrognathia and a decrease beyond 2 SD below the mean (0.96) as prognathism.


Assuntos
Cefalometria , Prognatismo/diagnóstico , Retrognatismo/diagnóstico , Adulto , Queixo/diagnóstico por imagem , Queixo/patologia , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Maxila/diagnóstico por imagem , Maxila/patologia , Mães , Prognatismo/diagnóstico por imagem , Prognatismo/patologia , Retrognatismo/diagnóstico por imagem , Retrognatismo/patologia
9.
Med Sci Monit ; 26: e921401, 2020 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-32588836

RESUMO

BACKGROUND The purpose of this prospective study was to compare adolescent and post-adolescent growth periods regarding the effectiveness of conventional activator appliance in patients with Class II mandibular retrognathia by using lateral cephalometric radiographs and three-dimensional photogrammetry (3dMDface). MATERIAL AND METHODS We enrolled 2 groups: 15 patients in the adolescent growth period and 17 patients in the post-adolescent growth period. All patients had Class II anomaly with mandibular retrognathia and were treated with conventional activator appliances. Lateral cephalometric radiographs and three-dimensional photogrammetric views were obtained at the beginning and end of the activator treatment of Class II patients. Maxillomandibular discrepancy, mandibular protrusion and lengths, convexity angles, facial heights, and dental measurements were evaluated cephalometrically. Projections of the lips and the chin and volumetric measurements of the lip and the mandibular area were assessed using three-dimensional photogrammetry. RESULTS Conventional activator therapy resulted in similar effects in both growth periods regarding improvements in the mandibular sagittal growth and maxillomandibular relationship (ANB° and the SNB° angles). Mandibular effective length was increased (Co-Gn length) and the maxillary horizontal growth was restricted (decreased SNA° angle) in both groups following the treatment. Treatment duration was significantly longer in the post-adolescent group. Increases in the projections of menton, pogonion, and sublabial points were observed in the three-dimensional photogrammetric views. Total lip volume was reduced while the mandibular volume was significantly increased in both groups. Lower gonial angle showed a greater increase in the post-adolescent group. CONCLUSIONS Correction of Class II anomaly with mandibular retrognathia was achieved with a combination of dental and skeletal changes in both growth periods. Conventional activator therapy may be an alternative treatment approach in the late growth period as it led to significant skeletal and dental changes.


Assuntos
Aparelhos Ativadores , Má Oclusão Classe II de Angle/terapia , Mandíbula/diagnóstico por imagem , Retrognatismo/terapia , Adolescente , Fatores Etários , Desenvolvimento Ósseo , Ossos do Carpo/diagnóstico por imagem , Ossos do Carpo/crescimento & desenvolvimento , Cefalometria , Criança , Feminino , Ossos da Mão/diagnóstico por imagem , Ossos da Mão/crescimento & desenvolvimento , Humanos , Imageamento Tridimensional , Masculino , Má Oclusão Classe II de Angle/diagnóstico por imagem , Mandíbula/anormalidades , Maxila/diagnóstico por imagem , Desenvolvimento Maxilofacial , Fotogrametria , Estudos Prospectivos , Retrognatismo/diagnóstico por imagem , Resultado do Tratamento
10.
J Perinat Med ; 47(9): 969-978, 2019 Nov 26.
Artigo em Inglês | MEDLINE | ID: mdl-31622251

RESUMO

Objective To determine whether the measurement of inferior facial angle (IFA) and prefrontal space ratio (PFSR) in two-dimensional (2D) ultrasound images in the first trimester of pregnancy is reliable and to describe these markers in normal and aneuploid fetuses. Methods IFA and PFSR were measured in stored 2D midsagittal images of 200 normal and 140 aneuploid fetal profiles between 11 + 0 and 13 + 6 weeks of gestation. Limits of agreement (LOAs) and intraclass correlation coefficients (ICCs) for inter- and intraobserver differences were calculated. Results The mean IFA in normal fetuses was 76.5° ± 6.3. Between the two measurement rounds of the same observer, the LOAs were -5.4 to 7.1 (obs. 1) and 7.4 to 8.4 (obs. 2). For IFA measurements by the same observer the ICC was 0.88 (obs. 1) and for measurements by two different observers the ICC was 0.74. The mean PFSR was 0.76 ± 0.40 and the intraobserver LOAs were -0.372 to 0.395 (obs. 1) and -0.555 to 0.667 (obs. 2). For PFSR measurements by the same observer the ICC was 0.89 (obs. 1) and for measurements by two different observers the ICC was 0.65. Among aneuploid fetuses, IFA was below the normal range in one third of the cases with trisomy 18. PFSR was below the 95% prediction limit in 16.2% of fetuses with trisomy 21% and 17.9% of fetuses with trisomy 18. Conclusion IFA can be reliably measured in 2D ultrasound images in the first trimester of pregnancy with a high interobserver agreement and may provide information about retrognathia associated with various syndromes and aneuploidies at early stages of pregnancy.


Assuntos
Aneuploidia , Face/diagnóstico por imagem , Primeiro Trimestre da Gravidez , Retrognatismo/diagnóstico por imagem , Ultrassonografia Pré-Natal/métodos , Síndrome de Down/diagnóstico por imagem , Síndrome de Down/embriologia , Face/embriologia , Feminino , Humanos , Masculino , Variações Dependentes do Observador , Gravidez , Reprodutibilidade dos Testes , Retrognatismo/embriologia , Retrognatismo/genética , Estudos Retrospectivos , Síndrome da Trissomia do Cromossomo 13/diagnóstico por imagem , Síndrome da Trissomia do Cromossomo 13/embriologia , Síndrome da Trissomía do Cromossomo 18/diagnóstico por imagem , Síndrome da Trissomía do Cromossomo 18/embriologia , Síndrome de Turner/diagnóstico por imagem , Síndrome de Turner/embriologia
11.
Int Orthod ; 17(2): 354-364, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31036464

RESUMO

The Herbst appliance (HA) is considered an efficient method to treat class II malocclusion characterized by mandibular retrusion. Nevertheless, HA is although hampered by side effects reducing its therapeutic potentialities. The association between HA and TADs in the lower arch has proved to be very effective in controlling lower incisor flaring. This case report shows that the insertion of TADs in both arches offers a satisfactory control of the vertical dimension, by avoiding a maxillary clockwise inclination.


Assuntos
Má Oclusão Classe II de Angle/terapia , Aparelhos Ortodônticos Funcionais , Retrognatismo/terapia , Técnicas de Movimentação Dentária/métodos , Adolescente , Parafusos Ósseos , Cefalometria , Humanos , Incisivo , Masculino , Má Oclusão Classe II de Angle/diagnóstico por imagem , Mandíbula , Maxila , Procedimentos de Ancoragem Ortodôntica/instrumentação , Desenho de Aparelho Ortodôntico , Aparelhos Ortodônticos Fixos , Radiografia Panorâmica , Retrognatismo/diagnóstico por imagem , Técnicas de Movimentação Dentária/instrumentação , Resultado do Tratamento , Dimensão Vertical
12.
J Appl Physiol (1985) ; 126(2): 330-340, 2019 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-30412031

RESUMO

The present study aimed to detail the relationship between the flow and structure characteristics of the upper airways and airway collapsibility in obstructive sleep apnea. Using a computational approach, we performed simulations of the flow and structure of the upper airways in two patients having different facial morphologies: retruding and protruding jaws, respectively. First, transient flow simulation was performed using a prescribed volume flow rate to observe flow characteristics within upper airways with an unsteady effect. In the retruding jaw, the maximum magnitude of velocity and pressure drop with velocity shear and vortical motion was observed at the oropharyngeal level. In contrast, in the protruding jaw, the overall magnitude of velocity and pressure was relatively small. To identify the cause of the pressure drop in the retruding jaw, pressure gradient components induced by flow were examined. Of note, vortical motion was highly associated with pressure drop. Structure simulation was performed to observe the deformation and collapsibility of soft tissue around the upper airways using the surface pressure obtained from the flow simulation. At peak flow rate, the soft tissue of the retruding jaw was highly expanded, and a collapse was observed at the oropharyngeal and epiglottis levels. NEW & NOTEWORTHY Aerodynamic characteristics have been reported to correlate with airway occlusion. However, a detailed mechanism of the phenomenon within the upper airways and its impact on airway collapsibility remain poorly understood. This study provides in silico results for aerodynamic characteristics, such as vortical structure, pressure drop, and exact location of the obstruction using a computational approach. Large deformation of soft tissue was observed in the retruding jaw, suggesting that it is responsible for obstructive sleep apnea.


Assuntos
Obstrução das Vias Respiratórias/fisiopatologia , Modelagem Computacional Específica para o Paciente , Prognatismo/fisiopatologia , Sistema Respiratório/fisiopatologia , Retrognatismo/fisiopatologia , Apneia Obstrutiva do Sono/fisiopatologia , Obstrução das Vias Respiratórias/diagnóstico por imagem , Obstrução das Vias Respiratórias/etiologia , Humanos , Dados Preliminares , Pressão , Prognatismo/complicações , Prognatismo/diagnóstico por imagem , Sistema Respiratório/diagnóstico por imagem , Retrognatismo/complicações , Retrognatismo/diagnóstico por imagem , Fatores de Risco , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/etiologia , Tomografia Computadorizada por Raios X
13.
J Radiol Case Rep ; 13(10): 1-5, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32184920

RESUMO

Emanuel syndrome is a rare inherited chromosomal abnormality caused by an unbalanced translocation of chromosomes 11 and 22. Clinically, Emanuel syndrome is characterized by a wide spectrum of congenital anomalies, dysmorphisms, and developmental disability often confused with other similar syndromes. Outside of genetic testing, diagnosis remains challenging and current literature on typical radiologic findings is limited. We present classic neuroimaging findings of Emanuel syndrome consistent with prior literature including microcephaly, microretrognathia, external auditory canal stenosis, and cleft palate; and also introduce the additional maxillofacial anomaly of dysplastic middle ear ossicles, to our knowledge not previously described in the literature. Recognition of findings leading to earlier diagnosis of Emanuel syndrome may improve outcomes and quality of life for patients and their families.


Assuntos
Transtornos Cromossômicos/diagnóstico por imagem , Fissura Palatina/diagnóstico por imagem , Cardiopatias Congênitas/diagnóstico por imagem , Deficiência Intelectual/diagnóstico por imagem , Microcefalia/diagnóstico por imagem , Hipotonia Muscular/diagnóstico por imagem , Constrição Patológica/diagnóstico por imagem , Meato Acústico Externo/anormalidades , Meato Acústico Externo/diagnóstico por imagem , Humanos , Hidrocefalia/diagnóstico por imagem , Bigorna/anormalidades , Bigorna/diagnóstico por imagem , Lactente , Masculino , Neuroimagem , Retrognatismo/diagnóstico por imagem , Espaço Subaracnóideo/diagnóstico por imagem , Tomografia Computadorizada por Raios X
14.
Am J Orthod Dentofacial Orthop ; 154(5): 708-717, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30384942

RESUMO

A 15-year-old girl with a convex profile and a retrognathic chin was referred for improvement of her profile. Nonextraction orthodontic therapy with temporary skeletal anchorage devices was used to improve her facial balance in a total active treatment time of 26 months. Her occlusion and profile were significantly improved by the treatment. Posttreatment records after 12 months showed excellent results with good occlusion and facial harmony.


Assuntos
Estética Dentária , Assimetria Facial/patologia , Assimetria Facial/terapia , Procedimentos de Ancoragem Ortodôntica , Retrognatismo/patologia , Retrognatismo/terapia , Adolescente , Cefalometria/métodos , Oclusão Dentária , Assimetria Facial/diagnóstico por imagem , Feminino , Humanos , Radiografia , Retrognatismo/diagnóstico por imagem , Resultado do Tratamento
15.
J Plast Reconstr Aesthet Surg ; 71(12): 1786-1795, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30172730

RESUMO

BACKGROUND: Maxillary retrognathia is a well-known consequence of abnormal facial growth in patients with cleft lip and palate. Orthognathic surgery improves facial appearance and occlusion but may induce velopharyngeal insufficiency. The aim of this study was to evaluate the effect of orthognathic surgery on velopharyngeal function by using speech analysis and lateral cephalometric radiographs. PATIENTS AND METHODS: We conducted a retrospective study of 47 patients who underwent maxillary advancement ±â€¯mandibular setback between 2006 and 2016. Preoperative and 1 year postoperative audio recordings were blinded for scoring by three trained speech therapists. Preoperative and 1 year postoperative lateral cephalometric radiographs were used to obtain information about skeletal movement and its relationship with the velopharyngeal area. Correlations between speech outcomes and cephalometric radiographs were determined. RESULTS: Hyponasality improved significantly after surgery (p < 0.05), whereas hypernasality deteriorated significantly only in patients who underwent maxillary advancement alone (p < 0.05). No difference in speech parameters was found between patients with hypernasality or patients who had a pharyngoplasty preoperatively and the rest of the group. No correlation was found between the amount of maxillary advancement and hypernasality. A significant correlation (r < -0.49, p < 0.05) was found between the preoperative velar length and hypernasality postoperatively. CONCLUSIONS: Maxillary advancement has a negative impact on velopharyngeal function, whereas bimaxillary surgery seems to protect from deterioration. No difference was found in the amount of maxillary advancement or in velopharyngeal measurements between the Le Fort I group and the bimaxillary group. A short soft palate is a predictor of hypernasality after orthognathic surgery.


Assuntos
Procedimentos Cirúrgicos Ortognáticos/métodos , Fala/fisiologia , Insuficiência Velofaríngea/fisiopatologia , Pontos de Referência Anatômicos , Cefalometria/métodos , Fenda Labial/fisiopatologia , Fissura Palatina/fisiopatologia , Feminino , Humanos , Masculino , Má Oclusão/diagnóstico por imagem , Má Oclusão/fisiopatologia , Mandíbula/diagnóstico por imagem , Mandíbula/cirurgia , Avanço Mandibular/métodos , Maxila/diagnóstico por imagem , Maxila/cirurgia , Osteotomia de Le Fort/métodos , Fonética , Radiografia , Retrognatismo/diagnóstico por imagem , Retrognatismo/fisiopatologia , Retrognatismo/cirurgia , Estudos Retrospectivos , Distúrbios da Fala/fisiopatologia , Distúrbios da Fala/cirurgia , Adulto Jovem
16.
J Craniomaxillofac Surg ; 46(9): 1470-1475, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30196856

RESUMO

The aim of this study was to assess condylar resorption, spatial change in glenoid cavity, and its risk factors after mandibular advancement by three-dimensional volumetric analysis. Subjects consisted of 30 condyles of 15 patients diagnosed with mandibular retrognathism who underwent Le Fort I and bilateral sagittal split ramus osteotomy advancement. CBCT images were taken before surgery (T0), immediately after surgery (T1), and postoperatively at 6 months (T2) and 1 year (T3). Condylar resorption was observed in 21 condyles. The posterior was the most affected region, while the anterior was the least affected. The volume of the glenoid cavity was significantly increased after surgery regardless of the presence or absence of resorption. However, the cavity recovered close to its original volume over time. At 1 year after surgery, the volume was not significantly different from the preoperative volume. Counterclockwise rotation of the proximal segment was found to be a risk factor affecting resorption based on correlation analysis. Mandibular advancement appeared to generate excessive mechanical stress on the posterior condyle, and might be responsible for the resorption. Counterclockwise rotation might have added stress to the region. Articular spatial change was transient and did not appear to be related to condyle resorption.


Assuntos
Tomografia Computadorizada de Feixe Cônico , Cavidade Glenoide/diagnóstico por imagem , Avanço Mandibular , Côndilo Mandibular/diagnóstico por imagem , Retrognatismo/cirurgia , Adulto , Reabsorção Óssea/patologia , Feminino , Cavidade Glenoide/patologia , Humanos , Imageamento Tridimensional , Masculino , Côndilo Mandibular/patologia , Osteotomia de Le Fort , Osteotomia Sagital do Ramo Mandibular , Retrognatismo/diagnóstico por imagem , Resultado do Tratamento
17.
Am J Orthod Dentofacial Orthop ; 154(3): 421-432, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30173846

RESUMO

This case report describes the nonsurgical treatment of an adolescent patient with a severe transverse discrepancy presented as a Brodie bite and retrognathic mandible. Distraction osteogenesis has been often used for similar cases in the literature. However, in this patient, a fixed appliance with 1 maxillary extraction combined with a functional appliance was used to resolve the transverse discrepancy with natural growth. After the orthodontic treatment, the impinging teeth and Brodie bite were corrected with a favorable occlusion and profile. Retention at the 3-year follow-up showed improved occlusal interdigitation and good stability.


Assuntos
Imageamento Tridimensional , Má Oclusão Classe II de Angle/diagnóstico por imagem , Má Oclusão Classe II de Angle/terapia , Aparelhos Ortodônticos Funcionais , Retrognatismo/diagnóstico por imagem , Retrognatismo/terapia , Cefalometria , Criança , Tomografia Computadorizada de Feixe Cônico , Humanos , Masculino , Modelos Dentários , Radiografia Panorâmica , Extração Dentária , Dente Supranumerário/cirurgia
18.
Br J Oral Maxillofac Surg ; 56(8): 750-752, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30139703

RESUMO

We describe a new approach to the planning of treatment and subsequent operation on a patient with syngnathia and severe mandibular retrognathism. To facilitate a large mandibular advancement we applied alloplastic temporomandibular joint (TMJ) prostheses to the coronoid processes after anticlockwise rotation of the mandible. To the best of our knowledge this is the first documented case of its kind.


Assuntos
Artroplastia de Substituição/métodos , Mandíbula/anormalidades , Avanço Mandibular/métodos , Maxila/anormalidades , Micrognatismo/cirurgia , Síndrome de Pierre Robin/diagnóstico por imagem , Síndrome de Pierre Robin/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Retrognatismo/cirurgia , Transtornos da Articulação Temporomandibular/cirurgia , Humanos , Prótese Articular , Masculino , Micrognatismo/diagnóstico por imagem , Retrognatismo/diagnóstico por imagem , Estereolitografia , Transtornos da Articulação Temporomandibular/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto Jovem
19.
Biomed Res Int ; 2018: 2568235, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29854734

RESUMO

AIM: To assess the three-dimensional (3D) maxillomandibular and dental response to Balters Bionator (BB) and the Sander Bite Jumping Appliance (SBJA) in growing patients. MATERIALS AND METHODS: Twenty-seven Class II division 1 patients (13 males, 14 females), consecutively treated with either the BB (9 females, 7 males; 10.1 ± 1.6 years) or SBJA (5 females, 6 males; 11 ± 1.9 years), were collected from a single orthodontic practice. All patients presented overjet ≥5 mm, full Class II or end-to-end molar relationship, mandibular retrusion. CBCT scans were available at T1 and after removal of the functional appliances (T2) with a mean interval of 18 months. The 3D location and direction of skeletal and dental changes with growth and treatment were quantitatively assessed. Statistical analysis was performed by means of Mann-Whitney U test (p < 0.05). RESULTS: Patients treated with the SBJA and BB orthopedic appliances presented, respectively, 4.7 mm and 4.5 mm of 3D displacement of the chin, with marked ramus growth of, respectively, 3.7 mm and 2.3 mm. While the mandible and maxilla grew downward and forward, no opening of the mandible plane was observed. Both appliances adequately controlled labial inclination of lower incisors (1.3° and 0.3°, for the SBJA and BB groups, resp.). No significant between-group differences were found for the T2-T1 changes for any of the variables, with the exception of molar displacements (significantly greater in the SBJA group than in the BB group, 1.2 mm and 0.9 mm, resp.). CONCLUSIONS: The maxillomandibular and dental growth responses to BB and SBJA therapies are characterized by vertical ramus growth and elongation of mandible that improve the maxillomandibular relationship with adequate control of lower incisor position.


Assuntos
Força de Mordida , Técnicas de Fixação da Arcada Osseodentária/instrumentação , Mandíbula/diagnóstico por imagem , Retrognatismo/diagnóstico por imagem , Aparelhos Ativadores , Adolescente , Criança , Oclusão Dentária , Feminino , Humanos , Incisivo/diagnóstico por imagem , Incisivo/crescimento & desenvolvimento , Masculino , Mandíbula/crescimento & desenvolvimento , Dente Molar/diagnóstico por imagem , Dente Molar/crescimento & desenvolvimento , Retrognatismo/fisiopatologia
20.
J Craniomaxillofac Surg ; 46(7): 1079-1090, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29773499

RESUMO

PURPOSE: To analyse the possible morphologic and positional changes of the mandibular condyles after orthognathic surgery. MATERIAL AND METHODS: A prospective cohort study was performed. Patients with mandibular retrognathism were surgically treated to advance the mandible. The study group included seventeen patients (34 condyles) treated with sagittal split osteotomies alone (4 patients) or in combination with maxillary osteotomies (13 patients). Only condyles located on the mandibular side that advance during surgery were studied, therefore only 25 condyles entered this prospective study. Beside it, a group of 6 patients undergoing maxillary surgery as only procedure, maxillary group, was also studied to determinate the influence of maxillary surgery on condylar displacement. Computed tomographies and lateral cephalometric radiographs were performed two weeks before surgery and one year after the surgical procedures. Different variables which analyse the position and morphology of the mandible were studied. The data obtained were analysed statistically by computing R2 values. RESULTS: In the maxillary group they were small displacements in magnitude and not significant. In the study group, 8 condyles showed morphological changes with alteration on reference points. In the remainder 17 condyles different displacements were noted after surgery. Several of these positional changes were predictable and did not affect postoperative mandibular stability. CONCLUSIONS: condylar displacements that occur after sagittal split osteotomies for mandibular advancement show significant correlation with the degree of mandibular advancement and can be defined by mathematical formulae. Maxillary osteotomies do not seem to influence condylar position when bimaxillary procedures take place.


Assuntos
Avanço Mandibular/métodos , Côndilo Mandibular/anatomia & histologia , Côndilo Mandibular/cirurgia , Osteotomia Sagital do Ramo Mandibular/métodos , Retrognatismo/cirurgia , Adulto , Cefalometria , Feminino , Humanos , Masculino , Côndilo Mandibular/diagnóstico por imagem , Pessoa de Meia-Idade , Estudos Prospectivos , Retrognatismo/diagnóstico por imagem , Retrognatismo/patologia , Tomografia Computadorizada por Raios X , Adulto Jovem
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