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1.
Sci Rep ; 11(1): 5204, 2021 03 04.
Artigo em Inglês | MEDLINE | ID: mdl-33664313

RESUMO

In 2016, undernutrition, as manifested in childhood stunting, wasting, and underweight were estimated to cause over 1.0 million deaths, 3.9% of years of life lost, and 3.8% of disability-adjusted life years globally. The objective of this study is to estimate the prevalence of undernutrition in low- and middle-income countries (LMICs) using the 2006-2018 cross-sectional nationally representative demographic and health surveys (DHS) data and to explore the sources of regional variations. Anthropometric measurements of children 0-59 months of age from DHS in 62 LMICs worldwide were used. Complete information was available for height-for-age (n = 624,734), weight-for-height (n = 625,230) and weight-for-age (n = 626,130). Random-effects models were fit to estimate the pooled prevalence of stunting, wasting, and underweight. Sources of heterogeneity in the prevalence estimates were explored through subgroup meta-analyses and meta-regression using generalized linear mixed-effects models. Human development index (a country-specific composite index based on life expectancy, literacy, access to education and per capita gross domestic product) and the United Nations region were explored as potential sources of variation in undernutrition. The overall prevalence was 29.1% (95% CI 26.7%, 31.6%) for stunting, 6.3% (95% CI 4.6%, 8.2%) for wasting, and 13.7% (95% CI 10.9%, 16.9%) for underweight. Subgroup analyses suggested that Western Africa, Southern Asia, and Southeastern Asia had a substantially higher estimated prevalence of undernutrition than global average estimates. In multivariable meta-regression, a combination of human development index and United Nations region (a proxy for geographical variation) explained 54%, 56%, and 66% of the variation in stunting, wasting, and underweight prevalence, respectively. Our findings demonstrate that regional, subregional, and country disparities in undernutrition remain, and the residual gaps to close towards achieving the second sustainable development goal-ending undernutrition by 2030.


Assuntos
Países em Desenvolvimento/economia , Transtornos do Crescimento/epidemiologia , Magreza/epidemiologia , Síndrome de Emaciação/epidemiologia , Pré-Escolar , Feminino , Transtornos do Crescimento/economia , Transtornos do Crescimento/metabolismo , Transtornos do Crescimento/patologia , Inquéritos Epidemiológicos , Humanos , Lactente , Recém-Nascido , Masculino , Desnutrição/economia , Desnutrição/epidemiologia , Desnutrição/patologia , Pobreza/economia , Magreza/economia , Magreza/patologia , Síndrome de Emaciação/economia , Síndrome de Emaciação/metabolismo , Síndrome de Emaciação/patologia
2.
PLoS One ; 15(11): e0241416, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33141831

RESUMO

A good understanding of the poor-non-poor gap in childhood development of severe wasting (SW) is a must in tackling the age-long critical challenge to health outcomes of vulnerable children in low- and middle-income countries (LMICs). There is a dearth of information about the factors explaining differentials in wealth inequalities in the distribution of SW in LMICs. This study is aimed at quantifying the contributions of demographic, contextual and proximate factors in explaining the poor-non-poor gap in SW in LMICs. We pooled successive secondary data from the Demographic and Health Survey conducted between 2010 and 2018 in LMICs. The final data consist of 532,680 under-five children nested within 55,823 neighbourhoods from 51 LMICs. Our outcome variable is having SW or not among under-five children. Oaxaca-Blinder decomposition was used to decipher poor-non-poor gap in the determinants of SW. Children from poor households ranged from 37.5% in Egypt to 52.1% in Myanmar. The overall prevalence of SW among children from poor households was 5.3% compared with 4.2% among those from non-poor households. Twenty-one countries had statistically significant pro-poor inequality (i.e. SW concentrated among children from poor households) while only three countries showed statistically significant pro-non-poor inequality. There were variations in the important factors responsible for the wealth inequalities across the countries. The major contributors to wealth inequalities in SW include neighbourhood socioeconomic status, media access, as well as maternal age and education. Socio-economic factors created the widest gaps in the inequalities between the children from poor and non-poor households in developing SW. A potential strategy to alleviate the burden of SW is to reduce wealth inequalities among mothers in the low- and middle-income countries through multi-sectoral and country-specific interventions with considerations for the factors identified in this study.


Assuntos
Países em Desenvolvimento , Disparidades nos Níveis de Saúde , Renda , Pobreza , Síndrome de Emaciação/economia , Síndrome de Emaciação/epidemiologia , Criança , Pré-Escolar , Características da Família , Humanos , Prevalência , Fatores de Risco , Fatores Socioeconômicos
3.
Nutr J ; 19(1): 20, 2020 02 27.
Artigo em Inglês | MEDLINE | ID: mdl-32106840

RESUMO

BACKGROUND: Multiple specialized nutritious food options are programmed for supplementation in humanitarian and development settings. However, comparative cost-effectiveness evidence is lacking, let alone incorporation of perspectives from uncompensated stakeholders. A Burkina Faso trial evaluated the cost-effectiveness of Corn Soy Blend Plus w/ oil (CSB+ w/oil, reference arm), Corn Soy Whey Blend w/oil (CSWB w/oil), Super Cereal Plus (SC+), and Ready-to-Use Supplementary Food (RUSF) in reducing stunting and wasting among children 6-23 months old. This paper presents cost-effectiveness findings from multiple stakeholders' perspectives, including caregivers and program volunteers. METHODS: An activity-based costing with ingredients approach was used to summarize cost of the 18-month-long blanket supplementary feeding for each enrolled child (in 2018 USD). Time data were collected using self-reported and observational instruments. Cost-effectiveness relative to CSB+ w/oil assessed incremental cost per enrolled child against incremental outcomes: prevalence of stunting at 23 months of age and number of months of wasting. Two combined perspectives were compared: program (donor, implementer, and volunteer) versus program and caregiver (adding caregiver). RESULTS: A total of 6112 children were enrolled. While similar effectiveness was found in three arms (CSWB w/oil was less effective), costs differed. Product cost and caregiver time to prepare study foods were major drivers of cross-arm cost differences from the respective combined perspective. The two major drivers were used to construct uncertainty ranges of cost per enrolled child from program and caregiver perspective: $317 ($279- $355) in CSB+ w/oil, $350 ($327- $373) in CSWB w/oil, $387 ($371- $403) in RUSF, and $434 ($365- $503) in SC+. Cost from program and caregiver perspective was a substantial increase from program perspective. CSB+ w/oil was most cost-effective in reducing stunting and wasting, and this main finding was robust to changing perspectives and all corresponding sensitivity analyses when uncompensated time was valued at minimum wage ($0.36/h). The break-even point for uncompensated time valuation is >$0.84/h, where RUSF became the most cost-effective from the program and caregiver perspective. Relative cost-effectiveness rankings among the other three arms depended on choice of perspectives, and were sensitive to values assigned to product cost, international freight cost, opportunity cost of time, and outcomes of a hypothetical control. Volunteer opportunity cost did not affect arm comparisons, but lack of compensation resulted in negative financial consequences for caregivers. CONCLUSIONS: Evaluating cost-effectiveness by incorporating uncompensated stakeholders provided crucial implementation insights around nutrition products and programming. TRIAL REGISTRATION: Trial registration number: NCT02071563. Name of registry: ClinicalTrials.gov URL of registry: https://clinicaltrials.gov/ct2/show/NCT02071563?type=Intr&cond=Malnutrition&cntry=BF&draw=2&rank=9 Date of registration: February 26, 2014. Date of enrollment of first participant: July 2014.


Assuntos
Análise Custo-Benefício/métodos , Alimentos Especializados/economia , Transtornos do Crescimento/prevenção & controle , Desnutrição/prevenção & controle , Síndrome de Emaciação/prevenção & controle , Burkina Faso , Análise Custo-Benefício/economia , Análise Custo-Benefício/estatística & dados numéricos , Feminino , Transtornos do Crescimento/economia , Humanos , Lactente , Masculino , Desnutrição/economia , Micronutrientes , Síndrome de Emaciação/economia
4.
Arch Dis Child ; 105(3): 229-235, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31601571

RESUMO

OBJECTIVE: To determine whether Rojiroti microfinance, for poor Indian women, improves child nutrition. DESIGN: Cluster randomised trial. SETTING: Tolas (village communities) in Bihar State. PARTICIPANTS: Women and children under 5 years. INTERVENTIONS: With Rojiroti microfinance, women form self-help groups and save their money to provide loans to group members. After 6 months, they receive larger external loans. Tolas were randomised to receive Rojiroti immediately or after 18 months. OUTCOME MEASURES: The primary analysis compared the mean weight for height Z score (WHZ) of children under 5 years in the intervention versus control tolas who attended for weight and height measurement 18 months after randomisation. Secondary outcomes were weight for age Z score (WAZ), height for age Z score, mid-upper arm circumference (MUAC), wasting, underweight and stunting. RESULTS: We randomised 28 tolas to each arm and collected data from 2469 children (1560 mothers) at baseline and 2064 children (1326 mothers) at follow-up. WHZ was calculated for 1718 children at baseline and 1377 (674 intervention and 703 control) at follow-up. At 18 months, mean WHZ was significantly higher for intervention (-1.02) versus controls (-1.37; regression coefficient adjusted for clustering ß=0.38, 95% CI 0.16 to 0.61, p=0.001). Significantly fewer children were wasted in the intervention group (122, 18%) versus control (200, 29%; OR=0.46, 95% CI 0.28 to 0.74, p=0.002). Mean WAZ was better in the intervention group (-2.13 vs -2.37; ß=0.27, 95% CI 0.11 to 0.43, p=0.001) as was MUAC (13.6 cm vs 13.4 cm; ß=0.22, 95% CI 0.03 to 0.40, p=0.02). In an analysis adjusting for baseline nutritional measures (259 intervention children and 300 control), only WAZ and % underweight showed significant differences in favour of the intervention. CONCLUSION: In marginalised communities in rural India, child nutrition was better in those who received Rojiroti microfinance, compared with controls. TRIAL REGISTRATION NUMBER: NCT01845545.


Assuntos
Transtornos da Nutrição Infantil/economia , Financiamento Pessoal/economia , Estatura/fisiologia , Peso Corporal/fisiologia , Transtornos da Nutrição Infantil/prevenção & controle , Pré-Escolar , Análise por Conglomerados , Estudos de Viabilidade , Feminino , Transtornos do Crescimento/economia , Transtornos do Crescimento/prevenção & controle , Humanos , Índia , Masculino , Estado Nutricional , Pobreza , Características de Residência , Saúde da População Rural/economia , Grupos de Autoajuda , Resultado do Tratamento , Síndrome de Emaciação/economia , Síndrome de Emaciação/prevenção & controle
5.
J Sci Food Agric ; 98(2): 429-438, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28685828

RESUMO

The status of food and nutrition security and its underlying factors in the Hindu-Kush Himalayan (HKH) region is investigated. In this region, one third to a half of children (<5 years of age) suffer from stunting, with the incidence of wasting and under-weight also being very high. The prevalence of stunting, wasting and under-weight in children is particularly high in some mountain areas such as Meghalaya state in India, the western mountains and far-western hills of Nepal, Balochistan province in Pakistan, eastern Afghanistan, and Chin state in Myanmar. Food habits in the HKH region are changing. This has led to a deterioration in traditional mountain food systems with a decline in agrobiodiversity. Factors such as high poverty and low dietary energy intakes, a lack of hygienic environments, inadequate nutritional knowledge, and climate change and environmental degradation are also influencing food and nutrition security in the HKH region. To achieve sustainable food and nutrition security in the mountains, this study suggests a multi-sectoral integrated approach with consideration of nutritional aspects in all development processes dealing with economic, social, agricultural and public health issues. © 2017 Society of Chemical Industry.


Assuntos
Transtornos do Crescimento/epidemiologia , Estado Nutricional , Magreza/epidemiologia , Síndrome de Emaciação/epidemiologia , Afeganistão/epidemiologia , Pré-Escolar , Feminino , Transtornos do Crescimento/economia , Transtornos do Crescimento/metabolismo , Humanos , Índia/epidemiologia , Lactente , Masculino , Mianmar/epidemiologia , Nepal/epidemiologia , Paquistão/epidemiologia , Pobreza , Saúde Pública/economia , Magreza/economia , Magreza/metabolismo , Síndrome de Emaciação/economia , Síndrome de Emaciação/metabolismo
6.
Lancet Glob Health ; 2(4): e225-34, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25103063

RESUMO

BACKGROUND: Economic growth is widely regarded as a necessary, and often sufficient, condition for the improvement of population health. We aimed to assess whether macroeconomic growth was associated with reductions in early childhood undernutrition in low-income and middle-income countries. METHODS: We analysed data from 121 Demographic and Health Surveys from 36 countries done between Jan 1, 1990, and Dec 31, 2011. The sample consisted of nationally representative cross-sectional surveys of children aged 0-35 months, and the outcome variables were stunting, underweight, and wasting. The main independent variable was per-head gross domestic product (GDP) in constant prices and adjusted for purchasing power parity. We used logistic regression models to estimate the association between changes in per-head GDP and changes in child undernutrition outcomes. Models were adjusted for country fixed effects, survey-year fixed effects, clustering, and demographic and socioeconomic covariates for the child, mother, and household. FINDINGS: Sample sizes were 462,854 for stunting, 485,152 for underweight, and 459,538 for wasting. Overall, 35·6% (95% CI 35·4-35·9) of young children were stunted (ranging from 8·7% [7·6-9·7] in Jordan to 51·1% [49·1-53·1] in Niger), 22·7% (22·5-22·9) were underweight (ranging from 1·8% [1·3-2·3] in Jordan to 41·7% [41·1-42·3] in India), and 12·8% (12·6-12·9) were wasted (ranging from 1·2% [0·6-1·8] in Peru to 28·8% [27·5-30·0] in Burkina Faso). At the country level, no association was seen between average changes in the prevalence of child undernutrition outcomes and average growth of per-head GDP. In models adjusted only for country and survey-year fixed effects, a 5% increase in per-head GDP was associated with an odds ratio (OR) of 0·993 (95% CI 0·989-0·995) for stunting, 0·986 (0·982-0·990) for underweight, and 0·984 (0·981-0·986) for wasting. ORs after adjustment for the full set of covariates were 0·996 (0·993-1·000) for stunting, 0·989 (0·985-0·992) for underweight, and 0·983 (0·979-0·986) for wasting. These findings were consistent across various subsamples and for alternative variable specifications. Notably, no association was seen between per-head GDP and undernutrition in young children from the poorest household wealth quintile. ORs for the poorest wealth quintile were 0·997 (0·990-1·004) for stunting, 0·999 (0·991-1·008) for underweight, and 0·991 (0·978-1·004) for wasting. INTERPRETATION: A quantitatively very small to null association was seen between increases in per-head GDP and reductions in early childhood undernutrition, emphasising the need for direct health investments to improve the nutritional status of children in low-income and middle-income countries. FUNDING: None.


Assuntos
Estatura , Peso Corporal , Transtornos da Nutrição Infantil/economia , Países em Desenvolvimento , Desenvolvimento Econômico , Produto Interno Bruto , Renda , Transtornos da Nutrição Infantil/epidemiologia , Transtornos da Nutrição Infantil/patologia , Pré-Escolar , Demografia , Feminino , Transtornos do Crescimento/economia , Transtornos do Crescimento/epidemiologia , Inquéritos Epidemiológicos , Humanos , Lactente , Recém-Nascido , Modelos Logísticos , Masculino , Razão de Chances , Pobreza , Prevalência , Magreza/economia , Magreza/epidemiologia , Síndrome de Emaciação/economia , Síndrome de Emaciação/epidemiologia
7.
Popul Stud (Camb) ; 68(1): 15-41, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23767406

RESUMO

Using data from the Indian National Family Health Surveys (1992-93, 1998-99, 2005-06), this study examined how the relationship between household wealth and child health evolved during a time of significant economic change in India. The main predictor was an innovative measure of household wealth that captures changes in wealth over time. Discrete-time logistic models (with community fixed effects) were used to examine mortality and malnutrition outcomes: infant, child, and under-5 mortality; stunting, wasting, and being underweight. Analysis was conducted at the national, urban/rural, and regional levels, separately for boys and girls. The results indicate that the relationship between household wealth and under-5 mortality weakened over time but this result was dominated by infant mortality. The relationship between wealth and child mortality stayed strong for girls. The relationship between household wealth and malnutrition became stronger over time for boys and particularly for girls, in urban and (especially) rural areas.


Assuntos
Proteção da Criança/estatística & dados numéricos , Renda/estatística & dados numéricos , Criança , Mortalidade da Criança , Transtornos da Nutrição Infantil/economia , Transtornos da Nutrição Infantil/epidemiologia , Proteção da Criança/economia , Pré-Escolar , Características da Família , Feminino , Humanos , Índia/epidemiologia , Lactente , Mortalidade Infantil , Modelos Logísticos , Masculino , População Rural/estatística & dados numéricos , Fatores Sexuais , Magreza/economia , Magreza/epidemiologia , População Urbana/estatística & dados numéricos , Síndrome de Emaciação/economia , Síndrome de Emaciação/epidemiologia
8.
East Mediterr Health J ; 19(3): 234-41, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23879074

RESUMO

This cross-sectional, community-based, household survey was carried out in Gaza City, Palestine during the first half of 2009 to study the nutritional status of Palestinian preschool children aged 2-5 years under blockade. The response rate was 95.2% from a total sample of 770. The majority (94.4%) of households faced difficulties accessing food, the main cause was the siege and the shortage of food products; and the majority (85.5%) were food insecure households. Just over 50% of the preschoolers were anaemic, 26.8% of those who had a stool test had parasitic infections, and 15.0 were stunted. Food insecurity was the first predictor of stunting andd underweight, and malnutrition indicators indicate the worst situation in the Gaza Strip for several decades.


Assuntos
Árabes/estatística & dados numéricos , Abastecimento de Alimentos/estatística & dados numéricos , Enteropatias Parasitárias/etnologia , Desnutrição/etnologia , Anemia/economia , Anemia/etnologia , Anemia/etiologia , Antropometria , Pré-Escolar , Análise por Conglomerados , Estudos Transversais , Feminino , Abastecimento de Alimentos/economia , Humanos , Enteropatias Parasitárias/economia , Israel/epidemiologia , Masculino , Desnutrição/complicações , Desnutrição/economia , Oriente Médio/etnologia , Análise Multivariada , Estado Nutricional , Política , Pobreza/etnologia , Síndrome de Emaciação/economia , Síndrome de Emaciação/etnologia , Síndrome de Emaciação/etiologia
9.
Asia Pac J Clin Nutr ; 21(4): 568-76, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23017315

RESUMO

Undernutrition among children under five year is a significant public health problem in India. The present study was carried out to assess trends in nutritional status, nutrient and food intake among children under five year over two time periods. It was a community-based cross-sectional study, carried out in tribal areas of India. A total of 14,587 children, 0-5 years old were covered for nutritional assessment in terms of underweight, stunting and wasting. A 24 hour diet survey was carried out in a sub-sample of households surveyed. Wealth index was constructed using principle component analysis. The prevalence of underweight and stunting had declined significantly over the periods (49% vs 57%, 51% vs 58%, respectively), while the prevalence of wasting remained similar (22% vs 23%). There was marginal decrease in the intake of foods and nutrients over the periods, and was below recommended levels. Stepwise regression showed that the risk of underweight and stunting was significantly (p<0.01) higher among children of illiterate mothers and children from lowest and middle households wealth index. Morbidities during preceding fortnight had 1.3 times higher risk of underweight and wasting. In conclusion, undernutrition is a significant health problem among tribal children and is associated with literacy status of mothers, household wealth index and morbidities. Therefore implementation of appropriate nutritional intervention strategies and improvement in households food security through public distribution systems, food intakes, socioeconomic condition, literacy of parents and personal hygiene may help in improving the nutritional status of tribal children.


Assuntos
Povo Asiático , Desenvolvimento Infantil , Dieta/efeitos adversos , Análise de Alimentos , Transtornos do Crescimento/etiologia , Desnutrição/etiologia , Pré-Escolar , Estudos Transversais , Dieta/economia , Dieta/etnologia , Escolaridade , Transtornos do Crescimento/economia , Transtornos do Crescimento/epidemiologia , Transtornos do Crescimento/etnologia , Humanos , Índia/epidemiologia , Lactente , Masculino , Desnutrição/economia , Desnutrição/epidemiologia , Desnutrição/etnologia , Mães/educação , Áreas de Pobreza , Prevalência , Saúde da População Rural/economia , Saúde da População Rural/etnologia , Fatores Socioeconômicos , Síndrome de Emaciação/economia , Síndrome de Emaciação/epidemiologia , Síndrome de Emaciação/etnologia , Síndrome de Emaciação/etiologia
10.
Asia Pac J Clin Nutr ; 21(3): 374-9, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22705426

RESUMO

Ready-to-Use Foods (RUFs) in the form of fortified cereal/nut/legume-based biscuits (±500 kcal and 8-10% protein per 100 g) were tested among mildly wasted children from October 2007 to June 2008, and were labelled as RUF-Nias biscuits. This study reports on a comparison of supplementary feeding program outcomes of mildly wasted children with weight-for-height z-score (WHZ) >=-2 to <-1.5 SD aged >=6 to <60 months old given locally produced RUF-Nias biscuits within daily (in semi-urban areas) and weekly (in rural remote regions) distribution and supervision program settings. In the Church World Service project area, all eligible children were recruited continuously from monthly community-based screening programs and admitted into existing nutrition centers managed by the community on Nias Island, Indonesia. Individual discharge criterion of the programs was WHZ >=-1.5 SD. Of the index children admitted in daily programs (n=51), 80.4% reached target WHZ, which was higher than in weekly programs (72.9%; n=48) by a similar length of stay of about 6 weeks. Weight gain of the children in daily programs was higher (3.1±3.6 g/kg body weight/day) than in weekly programs (2.0±2.1 g/kg body weight/day), and they achieved significantly higher WHZ at discharge. However, the majority of caretakers preferred weekly programs due to lower time constraints. Locally produced RUF in the form of biscuits for treatment of mild wasting among children demonstrated promising results both in daily and weekly community-based intervention programs.


Assuntos
Pão/análise , Desenvolvimento Infantil , Laticínios/análise , Dieta , Fast Foods/análise , Métodos de Alimentação , Síndrome de Emaciação/dietoterapia , Pão/economia , Cuidadores , Pré-Escolar , Serviços de Saúde Comunitária , Laticínios/economia , Dieta/economia , Dieta/etnologia , Fast Foods/economia , Feminino , Humanos , Indonésia , Lactente , Alimentos Infantis/análise , Alimentos Infantis/economia , Estudos Longitudinais , Masculino , Preferência do Paciente , Áreas de Pobreza , Índice de Gravidade de Doença , Síndrome de Emaciação/economia , Síndrome de Emaciação/etnologia , Aumento de Peso/etnologia
11.
Int J Technol Assess Health Care ; 28(1): 22-8, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22617735

RESUMO

INTRODUCTION: The supplementation of alanyl-glutamine dipeptide in critically ill patients necessitating total parenteral nutrition (TPN) improves clinical outcomes, reducing mortality, infection rate, and shortening intensive care unit (ICU) hospital lengths of stay (LOSs), as compared to standard TPN regimens. METHODS: A Discrete Event Simulation model that incorporates outcomes rates from 200 Italian ICUs for over 60,000 patients, alanyl-glutamine dipeptide efficacy data synthesized by means of a Bayesian random effects meta-analysis, and national cost data has been developed to evaluate the alternatives from the cost perspective of the hospital. Simulated clinical outcomes are death and infection rates in ICU, death rate in general ward, and hospital LOSs. Sensitivity analyses are performed by varying all uncertain parameter values in a plausible range. RESULTS: The internal validation process confirmed the accuracy of the model in replicating observed clinical data. Alanyl-glutamine dipeptide on average results more effective and less costly than standard TPN: reduced mortality rate (24.6% ± 1.6% vs. 34.5% ± 2.1%), infection rate (13.8% ± 2.9% vs. 18.8% ± 3.9%), and hospital LOS (24.9 ± 0.3 vs. 26.0 ± 0.3 days) come at a lower total cost per patient (23,409 ± 3,345 vs. 24,161 ± 3,523 Euro).Treatment cost is completely offset by savings on ICU and antibiotic costs. Sensitivity analyses confirmed the robustness of these results. CONCLUSIONS: Alanyl-glutamine dipeptide is expected to improve clinical outcomes and to do so with a concurrent saving for the Italian hospital.


Assuntos
Estado Terminal/economia , Suplementos Nutricionais/economia , Glutamina/economia , Nutrição Parenteral Total/economia , Síndrome de Emaciação/dietoterapia , Simulação por Computador , Análise Custo-Benefício , Suplementos Nutricionais/estatística & dados numéricos , Glutamina/uso terapêutico , Humanos , Unidades de Terapia Intensiva/economia , Unidades de Terapia Intensiva/estatística & dados numéricos , Itália , Tempo de Internação/estatística & dados numéricos , Modelos Econômicos , Nutrição Parenteral Total/métodos , Nutrição Parenteral Total/estatística & dados numéricos , Fatores de Tempo , Síndrome de Emaciação/economia
12.
Indian J Public Health ; 56(4): 305-7, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23354144

RESUMO

A community-based cross-sectional study was conducted to find out the prevalence of composite index of anthropometric failure (CIAF) among 117 slum dwelling under-five children in Bankura town, West Bengal and its relation with some common socio-economic factors. Among study population, the prevalence of underweight was 41.6%, whereas CIAF was 80.3%. CIAF gave a near complete estimation of undernutrition unlike underweight. Children who were unimmunized, with more number of siblings, living in a nuclear family, or with illiterate mothers were more likely to be undernourished.


Assuntos
Desnutrição/epidemiologia , Áreas de Pobreza , Magreza/epidemiologia , Síndrome de Emaciação/epidemiologia , Antropometria , Pré-Escolar , Estudos Transversais , Escolaridade , Feminino , Humanos , Índia/epidemiologia , Lactente , Recém-Nascido , Masculino , Desnutrição/economia , Mães/estatística & dados numéricos , Avaliação Nutricional , Estado Nutricional , Prevalência , Magreza/economia , Síndrome de Emaciação/economia
13.
J Res Health Sci ; 13(1): 58-62, 2012 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-23772007

RESUMO

BACKGROUND: The main objective of this study was to assess the malnutrition and some socio-economic related factors based on three ethnic groups among primary school children in north of Iran in 2010. METHODS: This cross-sectional study was carried out through multistage cluster random sampling on 5698 subjects (2505 Fars-native, 2154 Turkman, and 1039 Sistani) in 112 schools. Well-trained staffs completed the questionnaire and measured students' weight and height. Malnutrition estimated the Z-score less than -2SD for underweight, stunting and wasting were calculated using the cutoffs from WHO references. RESULTS: Generally, malnutrition was observed in 3.20%, 4.93% and 5.13% based on underweight, stunting and wasting respectively. It was more common in girls than in boys and in Sistani than in other ethnic groups. The correlation between malnutrition based on underweight and stunting and ethnicity was statistically significant (P=0.001). Results of logistic regression analyses showed that the risk of malnutrition was in rural area 1.34 times more than urban area, in girls 1.17 times more than boys, in Sistani ethnic group 1.82 times more than Fars-native ethnic group, in low economic families 2.01 times more than high economic families. CONCLUSION: Underweight, stunting and wasting are the health problems in primary school children in north of Iran with a higher prevalence in girls, in rural areas, and in Sistani ethnic group.


Assuntos
Transtornos do Crescimento/etnologia , Desnutrição/etnologia , Classe Social , Magreza/etnologia , Síndrome de Emaciação/etnologia , Antropometria , Criança , Estudos Transversais , Etnicidade/estatística & dados numéricos , Feminino , Transtornos do Crescimento/diagnóstico , Transtornos do Crescimento/economia , Humanos , Irã (Geográfico)/epidemiologia , Masculino , Desnutrição/diagnóstico , Desnutrição/economia , Pais/educação , Prevalência , Valores de Referência , Análise de Regressão , Saúde da População Rural/estatística & dados numéricos , Distribuição por Sexo , Magreza/diagnóstico , Magreza/economia , Saúde da População Urbana/estatística & dados numéricos , Síndrome de Emaciação/diagnóstico , Síndrome de Emaciação/economia
14.
PLoS Med ; 8(3): e1000424, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21408084

RESUMO

BACKGROUND: Economic growth is widely perceived as a major policy instrument in reducing childhood undernutrition in India. We assessed the association between changes in state per capita income and the risk of undernutrition among children in India. METHODS AND FINDINGS: Data for this analysis came from three cross-sectional waves of the National Family Health Survey (NFHS) conducted in 1992-93, 1998-99, and 2005-06 in India. The sample sizes in the three waves were 33,816, 30,383, and 28,876 children, respectively. After excluding observations missing on the child anthropometric measures and the independent variables included in the study, the analytic sample size was 28,066, 26,121, and 23,139, respectively, with a pooled sample size of 77,326 children. The proportion of missing data was 12%-20%. The outcomes were underweight, stunting, and wasting, defined as more than two standard deviations below the World Health Organization-determined median scores by age and gender. We also examined severe underweight, severe stunting, and severe wasting. The main exposure of interest was per capita income at the state level at each survey period measured as per capita net state domestic product measured in 2008 prices. We estimated fixed and random effects logistic models that accounted for the clustering of the data. In models that did not account for survey-period effects, there appeared to be an inverse association between state economic growth and risk of undernutrition among children. However, in models accounting for data structure related to repeated cross-sectional design through survey period effects, state economic growth was not associated with the risk of underweight (OR 1.01, 95% CI 0.98, 1.04), stunting (OR 1.02, 95% CI 0.99, 1.05), and wasting (OR 0.99, 95% CI 0.96, 1.02). Adjustment for demographic and socioeconomic covariates did not alter these estimates. Similar patterns were observed for severe undernutrition outcomes. CONCLUSIONS: We failed to find consistent evidence that economic growth leads to reduction in childhood undernutrition in India. Direct investments in appropriate health interventions may be necessary to reduce childhood undernutrition in India. Please see later in the article for the Editors' Summary.


Assuntos
Desenvolvimento Econômico , Transtornos do Crescimento/epidemiologia , Renda , Desnutrição/epidemiologia , Estado Nutricional , Magreza/epidemiologia , Síndrome de Emaciação/epidemiologia , Estatura , Pré-Escolar , Estudos Transversais , Feminino , Produto Interno Bruto , Transtornos do Crescimento/economia , Inquéritos Epidemiológicos , Humanos , Índia , Lactente , Modelos Logísticos , Masculino , Desnutrição/complicações , Desnutrição/economia , Prevalência , Fatores de Risco , Magreza/economia , Magreza/etiologia , Síndrome de Emaciação/economia
15.
Public Health Nutr ; 13(10): 1498-504, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20576197

RESUMO

OBJECTIVE: To determine how much of the variation in nutritional status of Bangladeshi children under 5 years old can be attributed to the socio-economic status of the family. DESIGN: Nutritional status used reference Z-scores of weight-for-age (WAZ), height-for-age (HAZ) and weight-for-height (WHZ). A 'possession score' was generated based on ownership of a radio, television, bicycle, motorcycle and telephone, and the availability of electricity, with categories of 0 to 4+ possessions. A five-point (quintile) 'poverty index' was created using principal component analysis. SETTING: The Bangladesh Demographic and Health Survey 2004 was the source of data. SUBJECTS: A sample of 4891 children aged <5 years was obtained. RESULTS: Some 57.8 % of the sample was either stunted, wasted or underweight (7.7 % were stunted, wasted and underweight). Of those stunted (48.4 %), 25.7 % were also underweight. Underweight and wasting prevalences were 40.7 % and 14.3 %, respectively. Mean WAZ, HAZ and WHZ did not differ by sex. Children of mothers with no education or no possessions were, on average, about 1 sd more underweight and stunted than those with higher educated mothers or with 4+ possessions. The possession score provided much greater discrimination of undernutrition than the poverty index. Nearly 50 % of children from households with no possessions were stunted, wasted or underweight (only 27 % in the poorest quintile), compared with only 3-6 % of children from households with 4+ possessions (over 13 % in the richest quintile). CONCLUSIONS: Maternal education and possession score were the main predictors of a child's nutritional status. Possession score was a much better indicator of undernutrition than the poverty index.


Assuntos
Estatura , Desnutrição/economia , Pobreza , Classe Social , Magreza/economia , Síndrome de Emaciação/economia , Bangladesh/epidemiologia , Pré-Escolar , Escolaridade , Feminino , Humanos , Modelos Logísticos , Masculino , Desnutrição/epidemiologia , Magreza/epidemiologia , Síndrome de Emaciação/epidemiologia
16.
BMC Public Health ; 8: 418, 2008 Dec 22.
Artigo em Inglês | MEDLINE | ID: mdl-19102755

RESUMO

BACKGROUND: Child under-nutrition is a leading factor underlying child mortality and morbidity in Sub-Saharan Africa. Several studies from Uganda have reported impaired growth, but there have been few if any community-based infant anthropometric studies from Eastern Uganda. The aim of this study was to describe current infant growth patterns using WHO Child Growth Standards and to determine the extent to which these patterns are associated with infant feeding practices, equity dimensions, morbidity and use of primary health care for the infants. METHODS: A cross-sectional survey of infant feeding practices, socio-economic characteristics and anthropometric measurements was conducted in Mbale District, Eastern Uganda in 2003; 723 mother-infant (0-11 months) pairs were analysed. Infant anthropometric status was assessed using z-scores for weight-for-length (WLZ), length-for-age (LAZ) and weight-for-age (WAZ). Dependent dichotomous variables were constructed using WLZ < -2 (wasting) and LAZ < -2 (stunting) as cut-off values. A conceptual hierarchical framework was used as the basis for controlling for the explanatory factors in multivariate analysis. Household wealth was assessed using principal components analysis. RESULTS: The prevalences of wasting and stunting were 4.2% and 16.7%, respectively. Diarrhoea during the previous 14 days was associated with wasting in the crude analysis, but no factors were significantly associated with wasting in the adjusted analysis. The adjusted analysis for stunting showed associations with age and gender. Stunting was more prevalent among boys than girls, 58.7% versus 41.3%. Having brothers and/or sisters was a protective factor against stunting (OR 0.4, 95% CI 0.2-0.8), but replacement or mixed feeding was not (OR 2.7, 95% CI 1.0-7.1). Lowest household wealth was the most prominent factor associated with stunting with a more than three-fold increase in odds ratio (OR 3.5, 95% CI 1.6-7.8). This pattern was also seen when the mean LAZ was investigated across household wealth categories: the adjusted mean difference between the top and the bottom wealth categories was 0.58 z-scores, p < 0.001. Those who had received pre-lacteal feeds had lower adjusted mean WLZ than those who had not: difference 0.20 z-scores, p = 0.023. CONCLUSION: Sub-optimal infant feeding practices after birth, poor household wealth, age, gender and family size were associated with growth among Ugandan infants.


Assuntos
Desenvolvimento Infantil/fisiologia , Transtornos da Nutrição do Lactente/epidemiologia , Desnutrição/epidemiologia , Síndrome de Emaciação/epidemiologia , Antropometria , Fenômenos Biológicos , Peso Corporal/fisiologia , Aleitamento Materno , Estudos Transversais , Características da Família , Feminino , Crescimento/fisiologia , Humanos , Lactente , Alimentos Infantis/análise , Alimentos Infantis/economia , Transtornos da Nutrição do Lactente/complicações , Transtornos da Nutrição do Lactente/economia , Fenômenos Fisiológicos da Nutrição do Lactente , Recém-Nascido , Masculino , Desnutrição/complicações , Desnutrição/economia , Prevalência , Características de Residência , Fatores Socioeconômicos , Uganda/epidemiologia , Síndrome de Emaciação/economia , Síndrome de Emaciação/etiologia
17.
Am J Public Health ; 97(2): 229-32, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17194868

RESUMO

We performed a cross-sectional, community-based survey, supplemented by interviews with community leaders in Chiapas, Mexico, to examine the prevalence and predictors of child malnutrition in regions affected by the Zapatista conflict. The prevalence rates of stunting, wasting, and underweight were 54.1%, 2.9%, and 20.3%, respectively, in 2666 children aged younger than 5 years. Stunting was associated with indigenous ethnicity, poverty, region of residence, and intracommunity division. The results indicate that malnutrition is a serious public health problem in the studied regions.


Assuntos
Transtornos da Nutrição Infantil/etnologia , Proteção da Criança/etnologia , Conflito Psicológico , Inquéritos Epidemiológicos , Indígenas Norte-Americanos/estatística & dados numéricos , Transtornos da Nutrição do Lactente/etnologia , Desnutrição/etnologia , Violência , Transtornos da Nutrição Infantil/epidemiologia , Proteção da Criança/economia , Pré-Escolar , Características da Família , Humanos , Lactente , Transtornos da Nutrição do Lactente/epidemiologia , Desnutrição/economia , Desnutrição/epidemiologia , México/epidemiologia , Análise Multivariada , Política , Pobreza , Prevalência , Fatores Socioeconômicos , Magreza/economia , Magreza/etnologia , Síndrome de Emaciação/economia , Síndrome de Emaciação/etnologia
18.
Bull World Health Organ ; 78(1): 108-18, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-10686745

RESUMO

The effects of the January 1994 devaluation of the African Financial Community (CFA) franc on the nutritional situation of the populations concerned has been little documented. We report in this article on two nutritional cross-sectional surveys that were conducted before and after this devaluation (1993 and 1996) in two districts of Brazzaville, Congo. The surveys involved a representative sample of 4206 households with a child aged 4-23 months. Complementary feeding practices and the anthropometric indices of the children and their mothers were compared, adjusting for changes in household socioeconomic characteristics. The results show a decline in the quality of the first complementary foods offered to the infants, i.e. less frequent use of special transitional foods and imported complementary flours (of higher nutritional quality), and preparation of less nutritious local gruels. Overall, the nutritional situation had deteriorated, with greater levels of stunting and wasting among children, mothers with lower body mass index, and infants with reduced birth weights. Increased food prices would appear to be the direct cause of the decreased quality in complementary feeding, but factors other than the devaluation have also had an impact on household welfare. The influence of these factors on nutritional-status is discussed.


Assuntos
Dieta/economia , Alimentos/economia , Fenômenos Fisiológicos da Nutrição do Lactente , Estado Nutricional , Fatores Socioeconômicos , Congo/epidemiologia , Dieta/tendências , Feminino , Humanos , Lactente , Mães , Inquéritos Nutricionais , Síndrome de Emaciação/economia , Síndrome de Emaciação/epidemiologia
19.
J Nutr ; 127(12): 2302-9, 1997 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9405578

RESUMO

We estimated the variability among nations in the prevalence of stunting and wasting, evaluated which national factors are associated with stunting and wasting and examined the relationship of stunting with wasting. The World Health Organization Global Database on Child Growth, a comprehensive conceptual model and a database of national factors were used with variance components and regression analyses. There was substantial variability among nations and among provinces within nations. Most national variability for stunting (76%) and wasting (66%) was explained by national factors and geographic region. Higher energy availability, female literacy and gross product were the most important factors associated with lower prevalence of stunting. The association of health expenditures and stunting differed by region. Higher immunization rate and, for Asia only, energy availability were the most important factors associated with lower prevalence of wasting. Regional differences in the relationship between stunting and wasting were accounted for by national factors. Some factors associated with stunting and wasting differ at the national level. Child malnutrition within a household is greatly influenced by issues at national and provincial levels, and intervention should be considered at all three levels.


Assuntos
Ingestão de Energia , Saúde Global , Gastos em Saúde , Síndrome de Emaciação/epidemiologia , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Escolaridade , Feminino , Humanos , Lactente , Masculino , Distúrbios Nutricionais/epidemiologia , Prevalência , Fatores Socioeconômicos , Síndrome de Emaciação/economia , Síndrome de Emaciação/etiologia
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