Assuntos
Dor no Peito/etiologia , Esôfago/diagnóstico por imagem , Síndrome de Plummer-Vinson/diagnóstico , Adulto , Dor no Peito/tratamento farmacológico , Ácido Cítrico , Esôfago/anormalidades , Feminino , Compostos Ferrosos/uso terapêutico , Fluoroscopia , Humanos , Síndrome de Plummer-Vinson/tratamento farmacológico , Oligoelementos/uso terapêuticoAssuntos
Anemia/diagnóstico , Anemia/tratamento farmacológico , Esôfago/cirurgia , Hematínicos/uso terapêutico , Síndrome de Plummer-Vinson/tratamento farmacológico , Síndrome de Plummer-Vinson/cirurgia , Adulto , Comorbidade , Feminino , Humanos , Síndrome de Plummer-Vinson/diagnóstico , Resultado do TratamentoRESUMO
BACKGROUND: Plummer-Vinson syndrome is characterized by a triad of dysphagia, iron deficiency anemia and esophageal web. Most of the patients are middle aged women in the fourth to seventh decade of life. OBJECTIVE: Very few cases of Plummer-Vinson syndrome affecting males have been reported. Here we report a series of male patients found to be suffering from Plummer-Vinson syndrome. METHODS: Five males presented to us with dysphagia and fatigue of various durations, from April to August, 2012. RESULTS: These patients were found to have iron deficiency anemia and esophageal web on subsequent investigations and were treated successfully with oral iron therapy. CONCLUSION: Plummer-Vinson syndrome is common in both males and females and can be successfully treated with oral iron therapy. The patients have an increased risk of developing gastrointestinal malignancies and should be thoroughly evaluated for the same.
Assuntos
Síndrome de Plummer-Vinson/diagnóstico , Adulto , Anemia Ferropriva/complicações , Transtornos de Deglutição/fisiopatologia , Esofagoscopia , Esôfago/fisiopatologia , Humanos , Ferro/uso terapêutico , Masculino , Saúde do Homem , Pessoa de Meia-Idade , Síndrome de Plummer-Vinson/tratamento farmacológico , Síndrome de Plummer-Vinson/etiologia , Doenças RarasRESUMO
Plummer-Vinson syndrome is characterised by dysphagia, anaemia, glossitis and oesophageal web. We report our findings in three patients with membranes in the upper oesophagus. All patients underwent endoscopic dilatation and iron replacement therapy, with good results. We review the literature of this syndrome.
Assuntos
Ferro/uso terapêutico , Síndrome de Plummer-Vinson/tratamento farmacológico , Administração Oral , Adulto , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
Plummer-Vinson syndrome is characterized by dysphagia, iron deficiency, anemia and the presence of esophageal web or webs. Two cases of this syndrome are reported in middle-aged women, which were treated over the last eight years. Both patients presented with dysphagia, anemia, sideropenia, glossitis and cheilitis. Radiological examination of the pharynx showed the presence of webs in both cases. The patients were treated with iron supplementation, which resulted in elimination of the symptoms. Both patients remain in good general condition and without any dysphagic complaints, 5 and 8 years after the diagnosis, respectively.
Assuntos
Síndrome de Plummer-Vinson , Adulto , Diagnóstico Diferencial , Esôfago/anormalidades , Feminino , Humanos , Ferro/uso terapêutico , Pessoa de Meia-Idade , Síndrome de Plummer-Vinson/diagnóstico , Síndrome de Plummer-Vinson/tratamento farmacológicoAssuntos
Estenose Esofágica/etiologia , Síndrome de Plummer-Vinson/diagnóstico , Cateterismo , Diagnóstico Diferencial , Estenose Esofágica/diagnóstico por imagem , Estenose Esofágica/terapia , Esofagoscopia , Feminino , Humanos , Compostos de Ferro/administração & dosagem , Pessoa de Meia-Idade , Síndrome de Plummer-Vinson/complicações , Síndrome de Plummer-Vinson/tratamento farmacológico , Radiografia , Resultado do TratamentoRESUMO
We report the case of a 41-year-old woman with Plummer-Vinson syndrome and an esophageal motility disorder. She complained of dysphagia and odynophagia and had cheilitis, glossitis, and hypochromic anemia. An esophageal motility study showed low amplitude of contraction and high intrabolus pressure in the esophageal body. After iron replacement, the patient was free from symptoms, and a new motility study showed increased amplitude of contraction and decreased intrabolus pressure.
Assuntos
Esôfago/fisiopatologia , Ferro/uso terapêutico , Síndrome de Plummer-Vinson/tratamento farmacológico , Síndrome de Plummer-Vinson/fisiopatologia , Adulto , Anemia Hipocrômica/complicações , Anemia Hipocrômica/tratamento farmacológico , Feminino , Humanos , Manometria , Contração Muscular/efeitos dos fármacosRESUMO
Plummer-Vinson syndrome has been brought to attention as a precancerous lesion of hypopharyngeal and cervical lesions of the esophagus, but that involving the stomach is uncommon. We report a case of Plummer-Vinson syndrome with gastric cancer. A brief literature review of this disorder is presented, and possible causes in this unusual case are discussed.