RESUMO
The flesh fly Sarcophaga carnaria is commonly used as fishing bait. Immunoglobulin (Ig) E-mediated reactions caused by the handling of this bait have been reported. The earthworm Dendrobaena species is increasingly being used as fishing bait but there have been no reported cases of allergy to this species to date. We studied a 26-year-old amateur angler who presented rhinoconjunctivitis, urticaria, and angioedema on handling S carnaria. He started to use Dendrobaena species instead but developed the same symptoms. The aim of this study was to identify the allergens involved in the patient's clinical reactions. The study was performed using immunoglobulin (Ig) E immunoblotting and immunoblotting inhibition assays.The patient's serum detected allergens from Dendrobaena species (of an apparent molecular weight of approximately 150, 60, 37, 24, 21 and 19 kDa) and S. carnaria (approximately 70 kDa and a smear ranging from 50 to 40 kDa). The patient was diagnosed with allergy to both Dendrobaena species and 5 carnaria. This is the first case describing Dendrobaena species as an allergic agent.
Assuntos
Conjuntivite Alérgica/etiologia , Dermatite Alérgica de Contato/etiologia , Oligoquetos/imunologia , Rinite Alérgica Perene/etiologia , Sarcofagídeos/imunologia , Adulto , Alérgenos/imunologia , Animais , Conjuntivite Alérgica/imunologia , Dermatite Alérgica de Contato/imunologia , Dermatoses da Mão/etiologia , Dermatoses da Mão/imunologia , Passatempos , Humanos , Imunoglobulina E/imunologia , Larva , Masculino , Rinite Alérgica Perene/imunologia , Testes CutâneosRESUMO
Pricking the body wall of Sarcophaga peregrina (flesh fly) larvae with a needle activated the immune system of this insect and induced various immune molecules, including antibacterial proteins, in the hemolymph. In this review, I summarize and discuss the functions of these immune molecules, with particular emphasis on the dual roles of some of these molecules in defense and development.