RESUMO
Necrotising sialometaplasia is a rare, benign and self-limiting inflammatory lesion that commonly involves minor salivary glands. Its clinical appearance, signs and symptoms very often mimic a carcinomatous lesion, thus creating a diagnostic dilemma for the clinician. Necrotising sialometaplasia being an important differential for an apparent carcinoma should be excluded histologically prior to radical therapy. It commonly occurs on the palatal mucosa following a palatal infiltration anaesthesia. The patient reports to the dentist with a sudden onset of painful ulcerations that rapidly increase in size. This case report describes the occurrence of necrotising sialometaplasia in a 46-year-old man with an unusual clinical presentation at multiple sites in the oral cavity. The importance of history taking, thorough clinical examination and careful histopathological examination in diagnosing necrotising sialometaplasia is highlighted in this paper.
Assuntos
Anti-Inflamatórios/uso terapêutico , Metilprednisolona/administração & dosagem , Sialometaplasia Necrosante/tratamento farmacológico , Triancinolona/administração & dosagem , Biópsia , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Glândulas Salivares Menores/patologia , Sialometaplasia Necrosante/patologiaAssuntos
Granuloma/patologia , Granulomatose Orofacial/diagnóstico , Intubação/efeitos adversos , Sialometaplasia Necrosante/patologia , Neoplasias da Glândula Sublingual/patologia , Neoplasias da Língua/etiologia , Língua/patologia , Corticosteroides/uso terapêutico , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Sialometaplasia Necrosante/tratamento farmacológico , Sialometaplasia Necrosante/etiologia , Neoplasias da Glândula Sublingual/tratamento farmacológico , Neoplasias da Glândula Sublingual/etiologia , Neoplasias da Língua/diagnósticoRESUMO
Necrotizing sialometaplasia (NS) is a distinct, though rare disease of the salivary glands. Histologic findings in humans and dogs are identical, but the distribution of affected glands and clinical course are very different. Small terrier breeds are predisposed. Clinically, canine NS is characterized by nausea (i.e., ptyalism, lip smacking, gulping), dysphagia, and pain in the mandibular region. Surgical removal of the affected glands produces minimal, if any, improvement; however, transient administration of anticonvulsants has resulted in dramatic clinical improvement in three cases.
