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1.
Trials ; 25(1): 553, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39169395

RESUMO

BACKGROUND: Osteoarthritis (OA) contributes increasingly to disability worldwide. There is ample high-quality research on the treatment of knee and hip OA, whereas research on surgical and non-surgical treatment in hand OA is sparse. Limited evidence suggests that education and exercise may improve pain, function, stiffness, and grip strength in hand OA. The established surgical options in hand OA have disadvantages. Prostheses preserve motion but have a high complication rate, whereas fusions decrease function due to limited movement. There is an unmet need for high-quality research on treatment options for hand OA and a need for the development of effective and safe movement-sparing therapies. This study aims to compare the effects of a motion-preserving surgical treatment (denervation of the proximal interphalangeal (PIP) joint) with a patient education and exercise program on patient-reported outcomes and objective function in painful PIP OA. METHODS: In this parallel-group, two-armed, randomized, controlled superiority trial (RCT), 90 participants are assigned to surgical PIP joint denervation or education and exercise. Pain on load 1 year after intervention is the primary outcome measure. Secondary outcome measures include pain at rest, Patient-Rated Wrist and Hand Evaluation (PRWHE), HQ8 score, EQ5D-5L, objective physical function, complications, two-point discrimination, Mini Sollerman, consumption of analgesics, and the need for further surgery. Assessments are performed at baseline, 3 and 6 months, and 1 year after intervention. DISCUSSION: There are no previous RCTs comparing surgical and non-surgical treatment in PIP OA. If patient education plus exercise or PIP denervation improve function, these treatments could be implemented as first-line treatment options in PIP OA. However, if denervation does not achieve better results than non-surgical treatment, it is not justified to use in PIP OA. TRIAL REGISTRATION: Prospectively registered in ClinicalTrials.gov (NCT05980793) on 8 August 2023. URL https://classic. CLINICALTRIALS: gov/ct2/show/NCT05980793 .


Assuntos
Denervação , Terapia por Exercício , Articulações dos Dedos , Osteoartrite , Humanos , Denervação/métodos , Articulações dos Dedos/cirurgia , Osteoartrite/cirurgia , Osteoartrite/fisiopatologia , Osteoartrite/terapia , Resultado do Tratamento , Terapia por Exercício/métodos , Educação de Pacientes como Assunto , Feminino , Medição da Dor , Pessoa de Meia-Idade , Medidas de Resultados Relatados pelo Paciente , Masculino , Fatores de Tempo , Recuperação de Função Fisiológica , Idoso , Força da Mão , Ensaios Clínicos Controlados Aleatórios como Assunto , Estudos de Equivalência como Asunto
2.
Sichuan Da Xue Xue Bao Yi Xue Ban ; 55(4): 1014-1019, 2024 Jul 20.
Artigo em Chinês | MEDLINE | ID: mdl-39170000

RESUMO

Objective: To analyze the application value of dynamic and static complementary balance theory-based functional exercise combined with stepwise rehabilitation training in postoperative hip function recovery in patients undergoing total hip replacement (THR). Methods: The clinical data of 118 inpatients undergoing THR between June 2022 and June 2023 were retrospectively collected. Among the patients, 57 were given perioperative stepwise rehabilitation training (the control group), and 61 were given a combination of functional exercise based on static and dynamic complementary balance theory and stepwise rehabilitation training during the perioperative period (the combination group). The postoperative recovery status and the incidence of postoperative complications in the two groups were recorded. During postoperative recovery, the patients were assessed for pain with the visual analogue scale (VAS) and for self-efficacy with the Self-Efficacy for Rehabilitation Outcome Scale (SER). Hip function was measured and compared between the two groups at 2 weeks, 4 weeks and 8 weeks after surgery. Results: With regard to the primary outcome indicator, the postoperative length-of-stay was (7.63±1.36) d in the combination group, which was shorter than the (8.22±1.48) d in the control group, and the difference was statistically significant (t=2.257, P=0.026). As for the secondary outcome indicators, no statistically significant difference was observed in the incidence of postoperative complications between the two groups (4.92% vs. 14.04%) (P>0.05). The perioperative VAS scores in the two groups showed an interaction effect according to the repeated measurement variance test (P<0.05). The postoperative VAS scores in both groups declined significantly compared to the preoperative scores (P<0.05), and the VAS score decreased gradually over time after surgery (P<0.05). The VAS scores in the combination group at 7 and 14 days after surgery were lower than those in the control group (P<0.05). At 14 days after surgery, the scores for the coping and the task dimensions and the total score of SER increased in both groups compared with those at 3 days after surgery (P<0.05), with the combination group showing higher scores than the control group did (P<0.05). After surgery, the scores for the dimensions of deformity, pain, function, and joint mobility and the total score of the Harris Hip Scale revealed interaction effects in the two groups according to the repeated measurement variance test (P<0.05), with these scores increasing gradually over time after surgery (P<0.05), and the scores in the combination group were higher at 4 and 8 weeks after surgery compared to those in the control group (P<0.05). Conclusion: The combination of functional exercise based on dynamic and static complementary balance theory and stepwise rehabilitation training shows an advantage over stepwise rehabilitation training alone in enhancing the self-efficacy of THR patients, relieving the postoperative pain, shortening the length-of-stay, and improving the hip function in patients.


Assuntos
Artroplastia de Quadril , Terapia por Exercício , Recuperação de Função Fisiológica , Humanos , Artroplastia de Quadril/reabilitação , Estudos Retrospectivos , Terapia por Exercício/métodos , Período Pós-Operatório , Complicações Pós-Operatórias/prevenção & controle , Masculino , Feminino , Tempo de Internação , Pessoa de Meia-Idade , Idoso
3.
PLoS One ; 19(8): e0306816, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39172915

RESUMO

BACKGROUND: Exergames are a fun, viable, attractive, and safe way to engage in physical exercise for most patient populations, including older adults. Their use in the home environment enables an expanded understanding about its applicability and its impact on clinical outcomes that can contribute to improved functionality and quality of life in this population. This systematic review aimed to synthesize the evidence on the usability of exergames as a tool for home-based balance training in older adults. METHODS: The search was realized in 6 electronic databases and were included 1) randomized controlled trials with exergames home-based training as intervention, 2) studies involving older adults (aged 60 years or older) described as having impaired static or dynamic balance, 3) that compared the effects of exergames to usual care, health education or no intervention, and 4) reported usability and balance outcomes. The Cochrane Risk of Bias tool for randomized trials version 2 and the Grading of Recommendations Assessment, Development, and Evaluation were used to evaluate the methodological quality of studies and levels of evidence for outcomes. RESULTS: After screening 1107 records, we identified 4 trials were included. The usability score of exergames was classified as an acceptable, good, and feasible tool. The pooled effect indicated improvements in favor of the exergame group for functional balance by TUG test (MD = -5.90; 95%CI = -10.29 to -1.51) with low-certainty evidence and Tinetti scale (MD = 4.80; 95%CI = 3.36 to 6.24) with very low-certainty evidence. Analyzing the different immersion level, it was observed a significant difference in the experimental group for the immersive exergames (MD = -9.14; 95%CI = -15.51 to -2.77) with very low-certainty evidence. CONCLUSION: Exergames applied at home showed good usability and had significant effects on functional balance compared to usual care or no intervention, especially in the immersive modality. TRIAL REGISTRATION: PROSPERO registration number: CRD42022343290.


Assuntos
Terapia por Exercício , Equilíbrio Postural , Jogos de Vídeo , Humanos , Equilíbrio Postural/fisiologia , Idoso , Terapia por Exercício/métodos , Pessoa de Meia-Idade , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Masculino , Exercício Físico/fisiologia , Feminino
4.
PLoS One ; 19(8): e0301304, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39173016

RESUMO

INTRODUCTION: Patients with head and neck cancer (PwHNC) benefit from targeted exercise interventions: symptom relief, compensation for dysfunction, improvement in quality of life (QoL). Data on acceptance physical interventions in PwHNC are rare. The 'OSHO #94' trial investigates the short- and medium-term effects of individualized home exercise in PwHNC on QoL, physical activity and functionality. The study includes a feasibility phase (proof of concept) in order to evaluate the acceptance. Here we present the study protocol as well as the feasibility results. METHODS AND ANALYSIS: This prospective, multicentre, single-arm intervention study includes PwHNC ≥18 years of age in aftercare or palliative care with stable remission under immunotherapy. The study opened in January 01, 2021, with estimated completion by December 31, 2024. The PwHNC receive an individualized home exercise program consisting of mobilization, coordination, strengthening and stretching exercises. This should be carried out at least three times a week over 12 weeks for 15 to 30 minutes, supplemented by aerobic training two to three times a week for 30 minutes (intervention). Once weekly telephone calls with a physiotherapist are performed. Subsequently, there is a 12-week follow-up (FU) without exercise specifications/contact. Outcomes are measured before and after the intervention and following the FU. Primary outcome of the feasibility phase (n = 25) was the determination of the dropout rate during the intervention with a termination cut off if more than 30% PwHNC withdrew premature. The primary outcome of the OSHO #94' trial (N = 53) is the change in global QoL score from pre- to post-intervention (EORTC QLQ-C30). Secondary outcomes include clinical and patient-reported measures, training details as well as functional diagnostic data (e.g. level of physical activity, training frequency, flexibility, fall risk and aerobic performance). RESULTS: 25 PwHNC were enrolled onto the feasibility cohort. Only16% (4/25 patients) did not complete the study. Therefore, recruitment of PwHNC was continued. The dropout rate was adjusted from 30% (N = 60) to 20% (N = 53, calculated sample size n = 42 PwHNC and 20% (n = 11) to dropout). CONCLUSIONS: Individualized home exercise programs in PwHNC in aftercare seem feasible. Consequently, the aim is now to evaluate the short and medium-term effects of individualized home exercise.


Assuntos
Terapia por Exercício , Estudos de Viabilidade , Neoplasias de Cabeça e Pescoço , Qualidade de Vida , Humanos , Neoplasias de Cabeça e Pescoço/terapia , Terapia por Exercício/métodos , Estudos Prospectivos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Exercício Físico , Adulto
5.
Sci Rep ; 14(1): 18793, 2024 08 13.
Artigo em Inglês | MEDLINE | ID: mdl-39138247

RESUMO

A whiplash injury can alter neck muscle function, which remains years after the injury and may explain why symptoms such as persistent pain and disability occur. There is currently limited knowledge about dynamic neck muscle function in chronic whiplash-associated disorders (WAD), and about the extent to which altered muscle function can improve after rehabilitation. Ultrasound can detect mechanical neck muscle function by measuring real-time deformation and deformation rate in the muscles. This method was used for five dorsal neck muscles in participants with chronic WAD versus matched controls in resistant neck rotation. We obtained real-time, non-invasive ultrasound measurements using speckle tracking, multivariate analyses, and mixed-design ANOVA analyses. The results showed altered deformation in the three deepest neck muscle layers, with less deformation area in the WAD group compared to controls in rotation to the most painful side at baseline. Participants in the WAD group performed three months of neck-specific exercises, resulting in improved deformation in the deep neck muscles in WAD and with a similar deformation pattern to controls, and the significant group differences ceased. We reveal new and important insights into the capability of ultrasound to diagnose altered neck muscle function and evaluate an exercise intervention.


Assuntos
Terapia por Exercício , Músculos do Pescoço , Ultrassonografia , Traumatismos em Chicotada , Humanos , Traumatismos em Chicotada/diagnóstico por imagem , Traumatismos em Chicotada/fisiopatologia , Músculos do Pescoço/diagnóstico por imagem , Músculos do Pescoço/fisiopatologia , Masculino , Ultrassonografia/métodos , Feminino , Adulto , Estudos de Casos e Controles , Terapia por Exercício/métodos , Pessoa de Meia-Idade , Cervicalgia/diagnóstico por imagem , Cervicalgia/fisiopatologia , Cervicalgia/etiologia , Adulto Jovem
6.
Stud Health Technol Inform ; 316: 1094-1095, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39176571

RESUMO

This paper explores the significance of physical activity for individuals with intellectual disabilities and proposes an innovative approach using augmented reality exergames to promote adherence. An augmented reality-based app for sorting elements while walking was specifically designed and implemented. Exergames hold promise as effective interventions for promoting physical activity and improving the overall well-being of individuals with intellectual disabilities.


Assuntos
Realidade Aumentada , Terapia por Exercício , Deficiência Intelectual , Aplicativos Móveis , Jogos de Vídeo , Humanos , Deficiência Intelectual/reabilitação , Deficiência Intelectual/terapia , Terapia por Exercício/métodos , Exercício Físico
7.
J Neuroeng Rehabil ; 21(1): 141, 2024 Aug 12.
Artigo em Inglês | MEDLINE | ID: mdl-39135048

RESUMO

BACKGROUND: Patients with neurological disorders including stroke use rehabilitation to improve cognitive abilities, to regain motor function and to reduce the risk of further complications. Robotics-assisted tilt table technology has been developed to provide early mobilisation and to automate therapy involving the lower limbs. The aim of this study was to evaluate the feasibility of employing a feedback control system for heart rate (HR) during robotics-assisted tilt table exercise in patients after a stroke. METHODS: This feasibility study was designed as a case series with 12 patients ( n = 12 ) with no restriction on the time post-stroke or on the degree of post-stroke impairment severity. A robotics-assisted tilt table was augmented with force sensors, a work rate estimation algorithm, and a biofeedback screen that facilitated volitional control of a target work rate. Dynamic models of HR response to changes in target work rate were estimated in system identification tests; nominal models were used to calculate the parameters of feedback controllers designed to give a specified closed-loop bandwidth; and the accuracy of HR control was assessed quantitatively in feedback control tests. RESULTS: Feedback control tests were successfully conducted in all 12 patients. Dynamic models of heart rate response to imposed work rate were estimated with a mean root-mean-square (RMS) model error of 2.16 beats per minute (bpm), while highly accurate feedback control of heart rate was achieved with a mean RMS tracking error (RMSE) of 2.00 bpm. Control accuracy, i.e. RMSE, was found to be strongly correlated with the magnitude of heart rate variability (HRV): patients with a low magnitude of HRV had low RMSE, i.e. more accurate HR control performance, and vice versa. CONCLUSIONS: Feedback control of heart rate during robotics-assisted tilt table exercise was found to be feasible. Future work should investigate robustness aspects of the feedback control system. Modifications to the exercise modality, or alternative modalities, should be explored that allow higher levels of work rate and heart rate intensity to be achieved.


Assuntos
Terapia por Exercício , Estudos de Viabilidade , Frequência Cardíaca , Robótica , Reabilitação do Acidente Vascular Cerebral , Humanos , Frequência Cardíaca/fisiologia , Reabilitação do Acidente Vascular Cerebral/métodos , Reabilitação do Acidente Vascular Cerebral/instrumentação , Masculino , Robótica/métodos , Robótica/instrumentação , Feminino , Pessoa de Meia-Idade , Idoso , Terapia por Exercício/métodos , Terapia por Exercício/instrumentação , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/fisiopatologia , Biorretroalimentação Psicológica/métodos , Biorretroalimentação Psicológica/instrumentação , Adulto
8.
BMC Cardiovasc Disord ; 24(1): 433, 2024 Aug 17.
Artigo em Inglês | MEDLINE | ID: mdl-39153977

RESUMO

BACKGROUND: The elevated blood pressure (BP) and lower cardiac autonomic modulation (CAM) are associated with higher morbidity mortality risk among older adults. Although exercise is an important intervention for cardiovascular promotion, it is unclear whether combat sports training could benefit cardiovascular outcomes as much as autonomic in this population. This study compared the effects of 12 weeks of Muay Thai (MT) training against functional training (FT) on CAM and hemodynamic parameters in older adults. METHODS: The sample consisted of 50 older adults (41 women; 66.0 ± 5.3 years old), who were equaly randomized into FT (n = 25) and MT (n = 25) intervention groups. CAM was measured by 30-min rest heart rate variability. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and resting heart rate (RHR) were measured using an automatic oscillometric device. Pulse pressure (PP) and the double product (DP) were also calculated. The interventions were carried out three times a week, with 60-min length per session, during 12 consecutive weeks. The intensity of the interventions was measured using the subjective perception of exertion scale and by accelerometer. Two-factor repeated measures analysis of covariance was used for groups comparison, considering intervention group and body mass as factors. The 95% confidence interval of the difference (95%CIdif) was also calculated and the effect size was measured using partial eta squared (η2p). RESULTS: CAM indices did not show significant changes across moments and intervention groups. In hemodynamic parameters, only in DBP was there an effect of the moment (F1,39 = 8.206; P = 0.007; η2p = 0.174, large) and interaction effect between group*moment (F1,39 = 7.950; P = 0.008; η2p = 0.169, large). Specifically, the MT group at the post-training moment showed lower DBP (P = 0.010; 95%CIdif = -13.3; -1.89) in relation to the FT group. Furthermore, the MT group showed a decrease in DBP during training (P = 0.002; 95%CIdif = -10.3; -2.6). Also, an increase in training intensity was also found over the 12 weeks in FT, with no difference between the groups. CONCLUSION: After 12 weeks of MT practice there was a reduction in DBP compared to FT in older adults. TRIAL REGISTRATION: NCT03919968 Registration date: 01/02/2019.


Assuntos
Sistema Nervoso Autônomo , Pressão Sanguínea , Frequência Cardíaca , Hemodinâmica , Humanos , Feminino , Masculino , Idoso , Sistema Nervoso Autônomo/fisiopatologia , Fatores de Tempo , Pessoa de Meia-Idade , Resultado do Tratamento , Fatores Etários , Tailândia , Terapia por Exercício/métodos , Coração/inervação , População do Sudeste Asiático
9.
World J Gastroenterol ; 30(29): 3456-3460, 2024 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-39156504

RESUMO

Non-alcoholic fatty liver disease (NAFLD) is characterized by symptoms of excessive fat accumulation and steatosis in the liver without alcohol intake in patients. The associated pathogenic mechanism is not completely understood and there are no specific drugs for patients with NAFLD. Exercise and diet adherence are the best options for the management of NAFLD patients. Questionnaire associated analysis models of adherence to these interventions are used to assess their effectiveness in the management of NAFLD patients using specificity, sensitivity, and so on. Studies have indicated that the relative ratio of NAFLD can be reduced by physical activity with diet control. In the future, the pathogenesis of NAFLD should be clarified with stratified efforts to develop appropriate drugs, and both exercise and diet adherence should be optimized using better questionnaire design and evaluation models for patients with NAFLD.


Assuntos
Exercício Físico , Hepatopatia Gordurosa não Alcoólica , Cooperação do Paciente , Humanos , Hepatopatia Gordurosa não Alcoólica/dietoterapia , Inquéritos e Questionários/estatística & dados numéricos , Resultado do Tratamento , Terapia por Exercício/métodos , Fígado/patologia , Dieta/efeitos adversos
10.
J Med Internet Res ; 26: e48787, 2024 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-39159449

RESUMO

BACKGROUND: Virtual reality (VR) in different immersive conditions has been increasingly used as a nonpharmacological method for managing chronic musculoskeletal pain. OBJECTIVE: We aimed to assess the effectiveness of VR-assisted active training versus conventional exercise or physiotherapy in chronic musculoskeletal pain and to analyze the effects of immersive versus nonimmersive VR on pain outcomes. METHODS: This systematic review of randomized control trials (RCTs) searched PubMed, Scopus, and Web of Science databases from inception to June 9, 2024. RCTs comparing adults with chronic musculoskeletal pain receiving VR-assisted training were included. The primary outcome was pain intensity; secondary outcomes included functional disability and kinesiophobia. Available data were pooled in a meta-analysis. Studies were graded using the Cochrane Risk-of-Bias Tool version 2. RESULTS: In total, 28 RCTs including 1114 participants with some concerns for a high risk of bias were identified, and 25 RCTs were included in the meta-analysis. In low back pain, short-term outcomes measured post intervention showed that nonimmersive VR is effective in reducing pain (standardized mean difference [SMD] -1.79, 95% CI -2.72 to -0.87; P<.001), improving disability (SMD -0.44, 95% CI -0.72 to -0.16; P=.002), and kinesiophobia (SMD -2.94, 95% CI -5.20 to -0.68; P=.01). Intermediate-term outcomes measured at 6 months also showed that nonimmersive VR is effective in reducing pain (SMD -8.15, 95% CI -15.29 to -1.01; P=.03), and kinesiophobia (SMD -4.28, 95% CI -8.12 to -0.44; P=.03) compared to conventional active training. For neck pain, immersive VR reduced pain intensity (SMD -0.55, 95% CI -1.02 to -0.08; P=.02) but not disability and kinesiophobia in the short term. No statistical significances were detected for knee pain or other pain regions at all time points. In addition, 2 (8%) studies had a high risk of bias. CONCLUSIONS: Both nonimmersive and immersive VR-assisted active training is effective in reducing back and neck pain symptoms. Our study findings suggest that VR is effective in alleviating chronic musculoskeletal pain. TRIAL REGISTRATION: PROSPERO CRD42022302912; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=302912.


Assuntos
Dor Crônica , Dor Musculoesquelética , Realidade Virtual , Humanos , Dor Musculoesquelética/terapia , Dor Musculoesquelética/psicologia , Dor Crônica/terapia , Dor Crônica/psicologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Terapia de Exposição à Realidade Virtual/métodos , Adulto , Terapia por Exercício/métodos , Dor Lombar/terapia , Dor Lombar/psicologia , Masculino , Feminino
11.
J Rehabil Med ; 56: jrm18396, 2024 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-39145519

RESUMO

OBJECTIVE: This study aims to assess the impact of proprioceptive training strategies with dual-task exercises on gait in people with chronic stroke. STUDY DESIGN: Systematic review. PATIENTS: Chronic stroke. METHODS: Searches were conducted in accordance with PRISMA guidelines and PICOS criteria. PubMed, Web of Science, and Scopus databases were systematically searched from November 2020 to February 2022, for eligible clinical trials. Two independent reviewers thoroughly screened potential articles for relevance and assessed the methodology quality. In accordance with the GRADE, PICOS criteria, and Cochrane risk of bias tools, the authors included articles concerning the effectiveness of dual-task in proprioceptive training on gait parameters in people with chronic stroke. RESULTS: Of 3075 identified studies, 11 articles met the inclusion criteria: 7 were randomized clinical trials, 1 was not randomized, and 3 were observational studies. The overall quality of evidence, assessed using the GRADE framework, was high, indicating a high level of confidence in the systematic review's findings. The papers involved 393 stroke patients; 241 underwent dual-task in proprioceptive training, with 152 participants in other stroke rehabilitation; within the dual-task group, 71 engaged in cognitive tasks, and 170 participated in motor tasks. dual-task in proprioceptive training improved gait speed, cadence, stride time, stride length, and step length. The best effects were observed with training 3 times a week for 4 weeks, with each session lasting 30 minutes, on speed, cadence, stride length, and step length. CONCLUSION: Current evidence suggests that proprioceptive training strategies with dual-task exercises improved walking abilities in people with chronic stroke. Specifically, it enhanced gait speed, a key indicator of clinical severity.


Assuntos
Terapia por Exercício , Propriocepção , Reabilitação do Acidente Vascular Cerebral , Humanos , Reabilitação do Acidente Vascular Cerebral/métodos , Terapia por Exercício/métodos , Propriocepção/fisiologia , Marcha/fisiologia , Acidente Vascular Cerebral/fisiopatologia , Doença Crônica , Transtornos Neurológicos da Marcha/reabilitação , Transtornos Neurológicos da Marcha/fisiopatologia , Transtornos Neurológicos da Marcha/etiologia
12.
BMJ Open ; 14(8): e085241, 2024 Aug 17.
Artigo em Inglês | MEDLINE | ID: mdl-39153792

RESUMO

INTRODUCTION: Multiple sclerosis (MS) causes a broad range of symptoms, with physical function being one of the most disabling consequences according to patients themselves. Exercise effectively improves lower extremity physical function. Nonetheless, it is unknown which exercise modality is most effective and it remains challenging to keep persons with MS adhering to exercise over a longer period. Therefore, the present study aims to investigate how exercise booster sessions (EBS) influence the sustainability of exercise-induced effects on physical function, and furthermore, to investigate which exercise modality (aerobic training or resistance training) is most effective in terms of improving physical function. MATERIALS AND METHODS: This study is a multi-arm, parallel-group, open-label multicentre randomised controlled trial investigating the effects of EBS. Participants (n=150) are initially randomised to 12 weeks of either resistance training+usual care, aerobic training+usual care or usual care. After 12 weeks of intervention, participants in the exercise groups will again be randomised to either EBS+usual care or usual care during a 40-week follow-up period. The primary outcome is physical function (composite score based on 6-min walk test and five-time sit to stand), and the secondary outcomes are fatigue, cognition, physical activity, symptoms of depression and quality of life. ETHICS AND DISSEMINATION: The study is approved by the Central Denmark Region Committees on Health Research Ethics (1-10-72-237-21) and is registered at the Danish Data Protection Agency (2016-051-000001) and at Clinicaltrials.gov (NCT04913012). All study findings will be published in scientific peer-reviewed journals and presented at scientific conferences. TRIAL REGISTRATION NUMBER: NCT04913012.


Assuntos
Terapia por Exercício , Esclerose Múltipla , Qualidade de Vida , Treinamento Resistido , Humanos , Esclerose Múltipla/terapia , Treinamento Resistido/métodos , Terapia por Exercício/métodos , Adaptação Fisiológica , Ensaios Clínicos Controlados Aleatórios como Assunto , Exercício Físico/fisiologia , Masculino , Estudos Multicêntricos como Assunto , Adulto , Feminino , Fadiga
13.
Sci Rep ; 14(1): 19204, 2024 08 19.
Artigo em Inglês | MEDLINE | ID: mdl-39160147

RESUMO

Approximately 75% of stroke survivors have movement dysfunction. Rehabilitation exercises are capable of improving physical coordination. They are mostly conducted in the home environment without guidance from therapists. It is impossible to provide timely feedback on exercises without suitable devices or therapists. Human action quality assessment in the home setting is a challenging topic for current research. In this paper, a low-cost HREA system in which wearable sensors are used to collect upper limb exercise data and a multichannel 1D-CNN framework is used to automatically assess action quality. The proposed 1D-CNN model is first pretrained on the UCI-HAR dataset, and it achieves a performance of 91.96%. Then, five typical actions were selected from the Fugl-Meyer Assessment Scale for the experiment, wearable sensors were used to collect the participants' exercise data, and experienced therapists were employed to assess participants' exercise at the same time. Following the above process, a dataset was built based on the Fugl-Meyer scale. Based on the 1D-CNN model, a multichannel 1D-CNN model was built, and the model using the Naive Bayes fusion had the best performance (precision: 97.26%, recall: 97.22%, F1-score: 97.23%) on the dataset. This shows that the HREA system provides accurate and timely assessment, which can provide real-time feedback for stroke survivors' home rehabilitation.


Assuntos
Terapia por Exercício , Reabilitação do Acidente Vascular Cerebral , Dispositivos Eletrônicos Vestíveis , Humanos , Reabilitação do Acidente Vascular Cerebral/instrumentação , Reabilitação do Acidente Vascular Cerebral/métodos , Terapia por Exercício/métodos , Terapia por Exercício/instrumentação , Feminino , Masculino , Acidente Vascular Cerebral/fisiopatologia , Pessoa de Meia-Idade , Redes Neurais de Computação , Idoso , Adulto
14.
Int Ophthalmol ; 44(1): 351, 2024 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-39160282

RESUMO

Due to limited studies, we systematically reviewed evidence on the impact of physical exercise on intraocular pressure (IOP) in glaucoma patients, adhering to PRISMA guidelines. Using MEDLINE/Web of Science, PubMed, and Scopus, we selected English, Portuguese, or Spanish studies excluding case reports and yoga-based interventions. From 1001 records, 15 studies were independently evaluated. Evaluated through the MMAT scoring system, two quantitative randomised controlled studies scored 100% while 13 non-randomised studies averaged 84.62%. Our findings indicated that both aerobic and resistance training led to an immediate IOP reduction post-exercise. However, these findings were largely from single-session experiments. In contrast, the effects of longer-term exercise programmes on IOP varied. Although our review underscores the potential utility of exercise in IOP management, the evidence remains inconclusive due to variations in study design, participant demographics, and exercise parameters. This lack of consistency in the research highlights the necessity for larger, standardised, and longer-term studies to robustly corroborate these preliminary findings.


Assuntos
Exercício Físico , Glaucoma , Pressão Intraocular , Humanos , Pressão Intraocular/fisiologia , Glaucoma/fisiopatologia , Exercício Físico/fisiologia , Terapia por Exercício/métodos
15.
JMIR Res Protoc ; 13: e59755, 2024 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-39163589

RESUMO

BACKGROUND: Osteoarthritis of the hip joint is an increasing functional and health-related problem. The most common surgical treatment is hip replacement to reduce pain and improve function. Rehabilitation after total hip arthroplasty (THA) is not regulated in Austria and mostly depends on the patient's own initiative and possibilities. Functional deficits, such as valgus thrust of the leg, functional Trendelenburg gait, or Duchenne limp, are characteristic symptoms before and, due to the performance learning effect prior to surgery, also after the operation. Addressing these deficits is possible through neuromuscular-focused exercise therapy. The efficacy of such therapy relies significantly on the quality of performance, the frequency of exercise, and the duration of engagement. Enhancing sustainability is achievable through increased motivation and real-time feedback (RTF) on exercise execution facilitated by digital feedback systems. OBJECTIVE: This study will be performed to quantify the medium-term effectiveness of digital home exercise feedback systems on functional performance following THA. METHODS: A clinical trial with a cluster-randomized, 2-arm, parallel-group design with an 8-week intervention phase and subsequent follow-ups at 3 and 6 months postsurgery will be conducted. Feedback during exercising will be provided through a blended-care program, combining a supervised group exercise program with a self-developed digital feedback system for home exercise. In total, 70 patients will be recruited for baseline. The primary outcome parameters will be the frontal knee range of motion, pelvic obliquity, and lateral trunk lean. Secondary outcomes will be the sum scores of patient-reported outcomes and relevant kinematic, kinetic, and spatiotemporal parameters. RESULTS: The trial started in January 2024, and the first results are anticipated to be published by June 2025. RTF-supported home exercise is expected to improve exercise execution quality and therapeutic adherence compared to using paper instructions for excise guidance. CONCLUSIONS: The anticipated findings of this study aim to offer new insights into the effect of a blended-care program incorporating digital RTF on exercise therapy after unilateral THA, in addition to knowledge on the functional status 3 and 6 months postsurgery, for further improvement in the development of rehabilitation guidelines following THA. TRIAL REGISTRATION: ClinicalTrials.gov: NCT06161194; https://clinicaltrials.gov/study/NCT06161194. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/59755.


Assuntos
Artroplastia de Quadril , Terapia por Exercício , Humanos , Artroplastia de Quadril/reabilitação , Terapia por Exercício/métodos , Projetos Piloto , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Áustria , Osteoartrite do Quadril/cirurgia , Osteoartrite do Quadril/reabilitação , Ensaios Clínicos Controlados Aleatórios como Assunto
16.
Med Sci Monit ; 30: e945212, 2024 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-39164949

RESUMO

BACKGROUND The Vibro-Swing system consists of 2 spiraled tubes containing 4 steel balls that move to generate a vibrational musculoskeletal and nervous system stimulus. This study included 45 older adults and aimed to compare balance, muscle strength, and proprioception with and without a 6-week program of Pilates training using the Vibro-Swing system. MATERIAL AND METHODS The present study included 45 older adults (mean age: 78.31±4.50). The experimental group (n=24) underwent a Pilates with Vibro-Swing exercise. The control group (n=21) participated in regular Pilates exercise. Both groups engaged in exercise for 40-50 minutes per session, twice a week, for 6 weeks, resulting in a total of 12 intervention sessions. Assessments were conducted before and after the intervention. The pre-post test evaluated balance (gait analysis, 10-meter walk test [10 MWT], functional reach test [FRT]), muscle strength (Five Times Sit-to-Stand Test [FTSS], grip strength), and proprioception (wrist joint position sense [WRT_30°]). RESULTS The experimental group exhibited statistically significant differences in velocity, cadence, 10MWT, FRT, FTSS, right grip, left grip, and wrist joint position sense (extension 30°) between the pre- and post-test (P>0.05). The experimental group exhibited statistically significant differences in gait velocity, cadence, 10 MWT, FTSS, right grip strength, FRT, and [WRT_30°] results compared with the control group (P>0.05). CONCLUSIONS The Pilates with Vibro-Swing exercise resulted in greater improvements in balance, muscle strength, and wrist joint proprioception.


Assuntos
Técnicas de Exercício e de Movimento , Exercício Físico , Força Muscular , Equilíbrio Postural , Propriocepção , Vibração , Humanos , Equilíbrio Postural/fisiologia , Idoso , Feminino , Técnicas de Exercício e de Movimento/métodos , Força Muscular/fisiologia , Masculino , Propriocepção/fisiologia , Exercício Físico/fisiologia , Idoso de 80 Anos ou mais , Marcha/fisiologia , Terapia por Exercício/métodos , Força da Mão/fisiologia
17.
Sci Rep ; 14(1): 17788, 2024 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-39090183

RESUMO

COPD is a public health problem of global concern, which seriously affects the quality of life of patients and is also the third leading cause of death from non-communicable diseases. To investigate the effect of Ba duan jin exercise on lung function and the results of a 6-min walking trial in patients with stable COPD. Literature databases such as Web of Science, Embase, PubMed, Cochrane Library, Chinese Biomedical Literature (CBM), CNKI, Wanfang Data and VIP were searched by computer, the search period is up to January 2024. Literature screening, quality evaluation and data extraction were carried out independently by two researchers. And use RevMan 5.3 software and StataMP 18 (64-bit) software to process the relevant outcome indicators. A total of 16 RCT studies with 1184 patients were included. The meta-analysis results showed that compared with the control group, Ba Duan Jin exercise could improve FEV1 (MD = 0.29, 95% CI (0.20, 0.37), P < 0.0001), FEV1/FVC (%) (MD = 3.86, 95% CI (2.24, 5.47), P < 0.00001), and 6-min walking distance (MD = 45.41, 95% CI (33.93, 56.89), P < 0.00001) in stable COPD patients. The results of subgroup analysis based on the duration of the intervention cycle, research quality, and intervention frequency showed that periodic Ba Duan Jin exercise can significantly improve the relevant lung function levels to varying degrees. At the same time, the intervention effect of Ba Duan Jin exercise during the implementation process is also affected by the duration of the exercise cycle, exercise frequency, and the completion of the exercise plan. Ba Duan Jin exercise has a positive improvement effect on lung function and 6-min walking distance in stable COPD patients. In the process of exercise implementation, attention should be paid to cultivating exercise habits, stabilizing and improving attendance rates, and strictly implementing training techniques to achieve the best clinical outcomes for these patients.


Assuntos
Doença Pulmonar Obstrutiva Crônica , Caminhada , Humanos , Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Doença Pulmonar Obstrutiva Crônica/terapia , Pulmão/fisiopatologia , Terapia por Exercício/métodos , Qualidade de Vida , Testes de Função Respiratória , Teste de Caminhada
18.
Psychiatry Res ; 339: 116093, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39089188

RESUMO

Outdoor exercise can be a novelty and effective therapeutic strategy to achieve positive physical and mental health outcomes in persons with schizophrenia. The aim of this study was to assess the feasibility and effectiveness of a 24-weeks outdoor exercise program in the physical and mental health of persons with schizophrenia. Fifty-two outpatients with schizophrenia were conveniently assigned to a 24-weeks walking/jogging combined with cycling outdoor program (n = 23, male = 14) or control group (n = 29, male = 20). Demographic and clinical measures were collected. Physical health was evaluated using anthropometric measures, 6 min walk test, Eurofit and accelerometer. Mental health was evaluated using self-esteem, motivation for exercise and quality of life questionnaires. Attendance rate to the outdoor program was 92 %. The exercise program significantly decreased participant's body mass index and improved functional exercise capacity and balance. No effects were reported in the self-esteem, motivation for physical activity and quality of life. Significant decreases were found in abdominal strength, hand grip and self-esteem levels of the control group. The outdoor exercise combining walking/jogging and cycling was an effective intervention to decrease body mass index and to improve physical fitness. It can be suggested as a therapeutic approach with an important impact on the management of schizophrenia.


Assuntos
Terapia por Exercício , Exercício Físico , Estudos de Viabilidade , Qualidade de Vida , Esquizofrenia , Humanos , Masculino , Esquizofrenia/reabilitação , Esquizofrenia/terapia , Feminino , Adulto , Pessoa de Meia-Idade , Terapia por Exercício/métodos , Exercício Físico/fisiologia , Saúde Mental , Autoimagem , Psicologia do Esquizofrênico , Índice de Massa Corporal , Motivação/fisiologia , Resultado do Tratamento , Caminhada/fisiologia , Aptidão Física/fisiologia
19.
J Rehabil Med ; 56: jrm40188, 2024 Aug 05.
Artigo em Inglês | MEDLINE | ID: mdl-39101676

RESUMO

OBJECTIVE: Rehabilitation interventions for chronic pain typically include education, cognitive behavioural therapy, and exercise therapy, or a combination of these. A systematic review and meta-analysis of rehabilitation interventions for neuropathic pain was conducted. DESIGN: Randomized controlled trials were identified in PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and PsycINFO databases from inception up to 3 March 2022. SUBJECTS/PATIENTS: Adults with chronic (> 3 months) neuropathic pain. METHODS: Primary outcomes were pain intensity, pain-related disability, and work participation. Secondary outcomes were quality of life, emotional strain, insomnia, and adverse outcomes, according to VAPAIN guidelines. Analyses were made post-intervention, which was defined as the assessment point immediately following the intervention or at the first-time measurement conducted after the intervention period. RESULTS: In total, 15 studies (total population, n = 764) were incorporated. Most common interventions were cognitive behavioural programmes including acceptance and commitment therapy (n = 4), mindfulness-based interventions (n = 5), and yoga (n = 2). Psychological interventions reduced both pain intensity (SMD -0.49, 95% CI -0.88 to -0.10) and pain-related disability (SMD -0.51, 95% CI -0.98 to -0.03), whereas other interventions had an effect on pain intensity but not on pain-related disability. CONCLUSION: Rehabilitation interventions, and psychological interventions in particular, seem to be of value for patients with chronic neuropathic pain.


Assuntos
Terapia Cognitivo-Comportamental , Neuralgia , Ensaios Clínicos Controlados Aleatórios como Assunto , Humanos , Neuralgia/reabilitação , Neuralgia/terapia , Terapia Cognitivo-Comportamental/métodos , Terapia por Exercício/métodos , Qualidade de Vida , Dor Crônica/reabilitação , Dor Crônica/terapia , Medição da Dor , Atenção Plena/métodos , Yoga , Terapia de Aceitação e Compromisso/métodos
20.
Sci Rep ; 14(1): 18300, 2024 08 07.
Artigo em Inglês | MEDLINE | ID: mdl-39112599

RESUMO

Chronic Obstructive Pulmonary Disease (COPD) is a global health concern. Mind-body exercises like Tai Chi and Yoga are suggested as non-pharmacological interventions for COPD management. This meta-analysis evaluates mind-body exercises' impact on lung function and exercise capacity in stable COPD patients, aiming to assess their effectiveness in rehabilitation. A systematic search across various databases identified relevant randomized controlled trials until April 2024. Primary outcomes included lung function tests (FEV1, FVC, FEV1/FVC, FEV1%) and Six-Minute Walk Test (6MWT) results. The Standardized Mean Difference (SMD) measured intervention effects. Fifteen studies with 1047 participants were analyzed. Mind-body exercises significantly improved FEV1 (SMD = 0.87), FEV1/FVC (SMD = 0.19), FEV1% (SMD = 0.43), and 6MWT (SMD = 1.21) compared to standard care. Sensitivity and subgroup analyses confirmed result stability despite some heterogeneity.In conclusion, Mind-body exercises enhance lung function and exercise capacity in stable COPD patients. Integrating them into comprehensive rehabilitation programs is advisable. Further research should explore the specific impacts of different exercise types and intensities.


Assuntos
Doença Pulmonar Obstrutiva Crônica , Ensaios Clínicos Controlados Aleatórios como Assunto , Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Doença Pulmonar Obstrutiva Crônica/reabilitação , Humanos , Tolerância ao Exercício/fisiologia , Pulmão/fisiopatologia , Terapias Mente-Corpo/métodos , Testes de Função Respiratória , Tai Chi Chuan/métodos , Terapia por Exercício/métodos , Yoga
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