Primary hypoparathyroidism in one cat and two dogs

Background: Primary hypoparathyroidism (PH) is an endocrine disorder characterized by decreased production and/or release of parathyroid hormone (PTH). Dogs and cats are rarely affected, and typical clinical signs include an abrupt onset of neurological and neuromuscular signs. The diagnosis is based on the history, clinical signs, and laboratory findings of hypocalcaemia, as well as the exclusion of other causes of tetany. Treatment involves stabilization of serum calcium with specific therapy. This study aimed to report three cases of PH: two canine cases and the first feline case in Brazil. Cases: 1) A 8-year-old male Yorkshire terrier was brought to the clinic with a history of tetanic crisis. The owner reported that the animal had been previously diagnosed with epilepsy and since treated with phenobarbital. The physical examination revealed hyperthermia, tachypnea, tachycardia, salivation, and ataxia with hyperextension of the anterior and posterior limbs. Emergency treatment included intravenous (IV) administration of calcium gluconate, and the animal showed clinical improvement within an hour. Overall, the complete blood count was within the normal range, but the calcium and PTH levels were below the normal ranges. Therefore, PH was confirmed. Calcium carbonate and vitamin D3 supplementation were prescribed, and the treatment with phenobarbital was suspended. During the...

Primary hypoparathyroidism in one cat and two dogs

Background: Primary hypoparathyroidism (PH) is an endocrine disorder characterized by decreased production and/or release of parathyroid hormone (PTH). Dogs and cats are rarely affected, and typical clinical signs include an abrupt onset of neurological and neuromuscular signs. The diagnosis is based on the history, clinical signs, and laboratory findings of hypocalcaemia, as well as the exclusion of other causes of tetany. Treatment involves stabilization of serum calcium with specific therapy. This study aimed to report three cases of PH: two canine cases and the first feline case in Brazil. Cases: 1) A 8-year-old male Yorkshire terrier was brought to the clinic with a history of tetanic crisis. The owner reported that the animal had been previously diagnosed with epilepsy and since treated with phenobarbital. The physical examination revealed hyperthermia, tachypnea, tachycardia, salivation, and ataxia with hyperextension of the anterior and posterior limbs. Emergency treatment included intravenous (IV) administration of calcium gluconate, and the animal showed clinical improvement within an hour. Overall, the complete blood count was within the normal range, but the calcium and PTH levels were below the normal ranges. Therefore, PH was confirmed. Calcium carbonate and vitamin D3 supplementation were prescribed, and the treatment with phenobarbital was suspended. During the...(AU)

Canine hypoparathyroidism: case report / Hipoparatireoidismo canino: relato de caso

Primary hypoparathyroidism is an uncommon endocrinopathy in dogs, resulting from absolute or relative deficiency in the secretion of parathormone (PTH). The dog presented signs of hypocalcemia, including muscular spasms, tetany and cramps, evolving to tonic-clonic seizures and fever. Emergency therapy for hypocalcemia included glucose physiological solution at 0.45% and calcium gluconate administered intravenously. Diagnosis was confirmed by the presence of hypocalcemia, hyperphosphatemia and a decrease in parathormone (PTH).(AU)

O hipoparatireoidismo primário é uma endocrinopatia incomum em cães, resultante da deficiência absoluta ou relativa na secreção do paratormônio (PTH). O cão apresentava sinais de hipocalcemia, incluindo espasmos musculares, tetania e cãibras que evoluíram para convulsões tônico-clônicas e febre. A terapia de emergência para hipocalcemia incluiu solução glicofisiológica 0,45% e gluconato de cálcio por intravenosa. O diagnóstico foi confirmado pela presença de hipocalcemia, hiperfosfatemia e diminuição do paratormônio (PTH).(AU)