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1.
J Pediatr Orthop ; 44(2): e197-e202, 2024 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-37728105

RESUMO

BACKGROUND: Patients with certain spinal anomalies are at risk for rare but devastating spinal cord injuries under anesthesia. We created a Spine at Risk (SAR) program to evaluate and recommend precautions for such patients, including intraoperative neuromonitoring (IONM) use for the highest-risk patients. We aimed to review all monitored nonspine procedures to determine rate of potential spinal cord injuries avoided in those who would otherwise have been unmonitored. METHODS: We performed a retrospective review of our institutional SAR program from 2011 to 2019 to analyze the number of nonspine anesthetized procedures that were done under IONM, the characteristics of those that had an IONM alert; and the clinical outcomes. RESULTS: Of the 3,453 patients flagged for SAR review, 1121 (33%) received a precaution recommendation, and 359 (10% of all flagged) were given IONM recommendations. Of those, 57 patients (16% of recommendations, 2% of all flagged) had a total of 102 nonspine anesthetized procedures done under IONM. Seven patients had a total of 10 cases with IONM alerts. Two cases were aborted when improved signals could not be obtained after working through a checklist; one of these patients woke with transient neurological deficits. Signals improved to baseline in 7 cases by working through a signal loss checklist. One case was aborted preoperatively when monitorable baseline signals could not be obtained. CONCLUSIONS: In the highest-risk spinal anomaly patients, we monitored an average of 11.7 nonspine cases per year, with a 10% rate of IONM alerts, and no permanent neurological deficits. Although the majority of patients remain safe during procedures, in the most critical patients IONM allowed the team to identify and react to alerts that may have otherwise led to permanent neurological injury. This is the largest series of spinal cord-monitored nonspine pediatric cases. It is important for pediatric orthopedic surgeons to evaluate at-risk patients and recommend IONM where appropriate, to protect both patients and our procedural colleagues. LEVEL OF EVIDENCE: Case series, level IV.


Assuntos
Monitorização Neurofisiológica Intraoperatória , Traumatismos da Medula Espinal , Traumatismos do Sistema Nervoso , Humanos , Criança , Potencial Evocado Motor , Monitorização Neurofisiológica Intraoperatória/métodos , Traumatismos da Medula Espinal/prevenção & controle , Traumatismos da Medula Espinal/etiologia , Traumatismos do Sistema Nervoso/etiologia , Procedimentos Neurocirúrgicos/efeitos adversos , Procedimentos Neurocirúrgicos/métodos , Estudos Retrospectivos
2.
Orthop Clin North Am ; 53(2): 129-137, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35365257

RESUMO

Nerve injuries following total hip arthroplasty are rare but devastating complications. The most important modifiable risk factor remains the choice of hip approach and surgical technique applied. The risk of nerve injuries is related to technical complexity of the procedure and anatomic variability of the nerves. Surgeons should remain cognizant of inherent risk factors, variations in the course and branching patterns of different nerves, and technical considerations of the surgical approach to mitigate risks. This article reviews the literature on postsurgical nerve injuries following total hip arthroplasty and characterizes the influence of surgical approach on the risk of this complication.


Assuntos
Artroplastia de Quadril , Traumatismos do Sistema Nervoso , Artroplastia de Quadril/efeitos adversos , Artroplastia de Quadril/métodos , Humanos , Fatores de Risco , Traumatismos do Sistema Nervoso/etiologia
3.
CMAJ ; 194(1): E1-E12, 2022 01 10.
Artigo em Inglês | MEDLINE | ID: mdl-35012946

RESUMO

BACKGROUND: Operative vaginal delivery (OVD) is considered safe if carried out by trained personnel. However, opportunities for training in OVD have declined and, given these shifts in practice, the safety of OVD is unknown. We estimated incidence rates of trauma following OVD in Canada, and quantified variation in trauma rates by instrument, region, level of obstetric care and institutional OVD volume. METHODS: We conducted a cohort study of all singleton, term deliveries in Canada between April 2013 and March 2019, excluding Quebec. Our main outcome measures were maternal trauma (e.g., obstetric anal sphincter injury, high vaginal lacerations) and neonatal trauma (e.g., subgaleal hemorrhage, brachial plexus injury). We calculated adjusted and stabilized rates of trauma using mixed-effects logistic regression. RESULTS: Of 1 326 191 deliveries, 38 500 (2.9%) were attempted forceps deliveries and 110 987 (8.4%) were attempted vacuum deliveries. The maternal trauma rate following forceps delivery was 25.3% (95% confidence interval [CI] 24.8%-25.7%) and the neonatal trauma rate was 9.6 (95% CI 8.6-10.6) per 1000 live births. Maternal and neonatal trauma rates following vacuum delivery were 13.2% (95% CI 13.0%-13.4%) and 9.6 (95% CI 9.0-10.2) per 1000 live births, respectively. Maternal trauma rates remained higher with forceps than with vacuum after adjustment for confounders (adjusted rate ratio 1.70, 95% CI 1.65-1.75) and varied by region, but not by level of obstetric care. INTERPRETATION: In Canada, rates of trauma following OVD are higher than previously reported, irrespective of region, level of obstetric care and volume of OVD among hospitals. These results support a reassessment of OVD safety in Canada.


Assuntos
Traumatismos do Nascimento/epidemiologia , Complicações do Trabalho de Parto/epidemiologia , Forceps Obstétrico/efeitos adversos , Vácuo-Extração/efeitos adversos , Canal Anal/lesões , Traumatismos do Nascimento/etiologia , Canadá/epidemiologia , Feminino , Humanos , Incidência , Hemorragias Intracranianas/epidemiologia , Hemorragias Intracranianas/etiologia , Lacerações/epidemiologia , Lacerações/etiologia , Paralisia do Plexo Braquial Neonatal/epidemiologia , Paralisia do Plexo Braquial Neonatal/etiologia , Complicações do Trabalho de Parto/etiologia , Pelve/lesões , Gravidez , Fraturas Cranianas/epidemiologia , Fraturas Cranianas/etiologia , Traumatismos do Sistema Nervoso/epidemiologia , Traumatismos do Sistema Nervoso/etiologia , Uretra/lesões , Bexiga Urinária/lesões , Vagina/lesões
4.
Orthop Clin North Am ; 52(4): 451-479, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34538354

RESUMO

Craniocervical injuries (CCJs) account for 10% to 30% of all cervical spine trauma. An increasing number of patients are surviving these injuries due to advancements in automobile technology, resuscitation techniques, and diagnostic modalities. The leading injury mechanisms are motor vehicle crashes, falls from height, and sports-related events. Current treatment with urgent rigid posterior fixation of the occiput to the cervical spine has resulted in a substantial reduction in management delays expedites treatment of CCJ injuries. Within CCJ injuries, there is a spectrum of instability, ranging from isolated nondisplaced occipital condyle fractures treated nonoperatively to highly unstable injuries with severely distracted craniocervical dissociation. Despite the evolution of understanding and improvement in the management of cases regarding catastrophic failure to diagnose, subsequent neurologic deterioration still occurs even in experienced trauma centers. The purpose of this article is to review the injuries that occur at the CCJ with the accompanying anatomy, presentation, imaging, classification, management, and outcomes.


Assuntos
Articulação Atlantoaxial/lesões , Articulação Atlantoccipital/lesões , Vértebras Cervicais/lesões , Luxações Articulares , Osso Occipital/lesões , Traumatismos da Coluna Vertebral , Articulação Atlantoaxial/diagnóstico por imagem , Articulação Atlantoaxial/cirurgia , Articulação Atlantoccipital/diagnóstico por imagem , Articulação Atlantoccipital/cirurgia , Vértebra Cervical Áxis/diagnóstico por imagem , Vértebra Cervical Áxis/lesões , Vértebra Cervical Áxis/cirurgia , Atlas Cervical/diagnóstico por imagem , Atlas Cervical/lesões , Atlas Cervical/cirurgia , Vértebras Cervicais/diagnóstico por imagem , Vértebras Cervicais/cirurgia , Humanos , Luxações Articulares/complicações , Luxações Articulares/diagnóstico , Luxações Articulares/cirurgia , Luxações Articulares/terapia , Osso Occipital/diagnóstico por imagem , Osso Occipital/cirurgia , Fraturas da Coluna Vertebral/complicações , Fraturas da Coluna Vertebral/diagnóstico , Fraturas da Coluna Vertebral/cirurgia , Fraturas da Coluna Vertebral/terapia , Traumatismos da Coluna Vertebral/complicações , Traumatismos da Coluna Vertebral/diagnóstico , Traumatismos da Coluna Vertebral/cirurgia , Traumatismos da Coluna Vertebral/terapia , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/cirurgia , Traumatismos do Sistema Nervoso/terapia
5.
Orthop Clin North Am ; 52(4): 481-489, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34538355
6.
BMC Neurol ; 20(1): 433, 2020 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-33246421

RESUMO

BACKGROUND: Difficult procedures of severe rigid spinal deformity increase the risk of intraoperative neurological injury. Here, we aimed to investigate the preoperative and intraoperative risk factors for postoperative neurological complications when treating severe rigid spinal deformity. METHODS: One hundred seventy-seven consecutive patients who underwent severe rigid spinal deformity correction were assigned into 2 groups: the neurological complication (NC, 22 cases) group or non-NC group (155 cases). The baseline demographics, preoperative spinal cord functional classification, radiographic parameters (curve type, curve magnitude, and coronal/sagittal/total deformity angular ratio [C/S/T-DAR]), and surgical variables (correction rate, osteotomy type, location, shortening distance of the osteotomy gap, and anterior column support) were analyzed to determine the risk factors for postoperative neurological complications. RESULTS: Fifty-eight patients (32.8%) had intraoperative evoked potentials (EP) events. Twenty-two cases (12.4%) developed postoperative neurological complications. Age and etiology were closely related to postoperative neurological complications. The spinal cord functional classification analysis showed a lower proportion of type A, and a higher proportion of type C in the NC group. The NC group had a larger preoperative scoliosis angle, kyphosis angle, S-DAR, T-DAR, and kyphosis correction rate than the non-NC group. The results showed that the NC group tended to undergo high-grade osteotomy. No significant differences were observed in shortening distance or anterior column support of the osteotomy area between the two groups. CONCLUSIONS: Postoperative neurological complications were closely related to preoperative age, etiology, severity of deformity, angulation rate, spinal cord function classification, intraoperative osteotomy site, osteotomy type, and kyphosis correction rate. Identification of these risk factors and relative development of surgical techniques will help to minimize neural injuries and manage postoperative neurological complications.


Assuntos
Osteotomia/efeitos adversos , Complicações Pós-Operatórias/etiologia , Curvaturas da Coluna Vertebral/cirurgia , Traumatismos do Sistema Nervoso/epidemiologia , Traumatismos do Sistema Nervoso/etiologia , Adolescente , Adulto , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Osteotomia/métodos , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
7.
Kobe J Med Sci ; 65(3): E110-E113, 2020 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-32029696

RESUMO

BACKGROUND: Common peroneal nerve (CPN) injury following a knee dislocation is a serious problem, and an optimal treatment is yet to be established. We report a case of complete CPN palsy following a knee dislocation treated with sural nerve grafting. CASE: A 19-year-old man suffered a knee injury during a hurdle race. Diagnosis in a previous hospital revealed a complex ligament injury with CPN palsy. Ten weeks following injury, he was admitted to our institution because of a lack of neurological improvement. Considering the grade 0 results obtained in the manual muscle test (MMT) of tibialis anterior (TA) and extensor hallucis longus (EHL), the patient was diagnosed with complete neurotmesis of CPN, and surgery was performed. Operative findings revealed CPN discontinuity and an extended nerve defect length of 15 cm; therefore, sural nerve grafting was performed to repair the CPN injury. One year postoperatively, a grade 1 result from MMT of TA and EHL indicated a gradual neurological recovery. Three years postoperatively, MMT of TA and EHL showed significant improvement to grade 4+ and grade 4, respectively, and he could walk and jog without a knee brace. DISCUSSION: Nerve graft length of >6 cm has shown limited success, and their efficacy for the treatment of CPN palsy following knee dislocations is controversial. However, young patients with complete CPN lesion are more likely to recover regardless of the length of nerve injury. Therefore, in such cases, nerve grafting can be considered as one of the treatments for complete CPN lesion following knee dislocations.


Assuntos
Luxação do Joelho/complicações , Neuropatias Fibulares/etiologia , Neuropatias Fibulares/cirurgia , Nervo Sural/transplante , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/cirurgia , Humanos , Masculino , Músculo Esquelético/inervação , Músculo Esquelético/fisiopatologia , Nervo Fibular/fisiopatologia , Nervo Fibular/cirurgia , Neuropatias Fibulares/fisiopatologia , Transplante Homólogo , Adulto Jovem
8.
Int J Mol Sci ; 20(20)2019 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-31635068

RESUMO

Stroke is the second-leading cause of death globally and the leading cause of disability in adults. Medical complications after stroke, especially infections such as pneumonia, are the leading cause of death in stroke survivors. Systemic immunodepression is considered to contribute to increased susceptibility to infections after stroke. Different experimental models have contributed significantly to the current knowledge of stroke pathophysiology and its consequences. Each model causes different changes in the cerebral microcirculation and local inflammatory responses after ischemia. The vast majority of studies which focused on the peripheral immune response to stroke employed the middle cerebral artery occlusion method. We review various experimental stroke models with regard to microcirculatory changes and discuss the impact on local and peripheral immune response for studies of CNS-injury (central nervous system injury) induced immunodepression.


Assuntos
Doenças do Sistema Nervoso Central/complicações , Doenças do Sistema Imunitário/etiologia , Tolerância Imunológica , Microcirculação , Acidente Vascular Cerebral/patologia , Traumatismos do Sistema Nervoso/complicações , Animais , Biomarcadores , Doenças do Sistema Nervoso Central/etiologia , Modelos Animais de Doenças , Humanos , Doenças do Sistema Imunitário/metabolismo , Imunomodulação , Acidente Vascular Cerebral/etiologia , Acidente Vascular Cerebral/metabolismo , Traumatismos do Sistema Nervoso/etiologia
9.
Z Orthop Unfall ; 157(5): 574-596, 2019 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-31594004

RESUMO

The basis for assessing thoracolumbar vertebral body fractures are two established classification systems. Important, especially in terms of further treatment, is the distinction between osteoporotic and healthy bones. The AO Spine classification offers a comprehensive tool for healthy bones to reliably specify the morphological criterias (alignment, integrity of the intervertebral disc, fragment separation, stenosis of the spinal canal). In addition to the fracture morphology, the OF classification for osteoporotic fractures includes patient-specific characteristics to initiate adequate therapy. In general an adequate pain therapy is required for early rehabilitation. While in the bone healthy population, physiotherapy reduces the risk of muscle deconditioning, in the osteoporotic population it additionally serves to prevent subsequent fractures. Unlike osteoporotic patients, bone healthy patients with vertebral fractures should not undergo a corset/orthosis treatment.


Assuntos
Tratamento Conservador/métodos , Vértebras Lombares/lesões , Fraturas da Coluna Vertebral/terapia , Vértebras Torácicas/lesões , Educação Médica Continuada , Fraturas por Compressão/terapia , Humanos , Fraturas por Osteoporose/classificação , Fraturas por Osteoporose/terapia , Modalidades de Fisioterapia , Fraturas da Coluna Vertebral/classificação , Fraturas da Coluna Vertebral/complicações , Fraturas da Coluna Vertebral/diagnóstico , Traumatismos do Sistema Nervoso/classificação , Traumatismos do Sistema Nervoso/diagnóstico , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/terapia , Resultado do Tratamento
10.
Surg Technol Int ; 35: 441-446, 2019 11 10.
Artigo em Inglês | MEDLINE | ID: mdl-31282983

RESUMO

To clarify outcomes and develop a novel classification according to CSF fistula in a selective cohort with intraoperative spinal dural tear, we examined 72 consecutive patients who underwent spinal dural repair after microdiscectomy (n=42) or lumbar spinal decompression (n=30). Group 1 consisted of 25 patients with Type I (mild) dural tear who were treated with either tissue-glue-coated collagen sponge or fibrin glue. Group 2 consisted of 26 patients with Type II (moderate) dural tear who were treated with both tissue-glue-coated collagen sponge and fibrin glue. Group 3 consisted of 21 patients with Type III (severe) dural tear who were treated with polypropylene suture along with tissue-glue-coated collagen sponge and/or fibrin glue. Evident postoperative internal or external CSF leak was used to determine the patient's postoperative result. Postoperative internal or external CSF leak was not evident during a minimum 1-year follow-up in Group 1. In contrast, internal CSF leak was evident in both Groups 2 (n=3) and 3 (n=3) during the same follow-up. No external CSF leak was noted in any of the patients. Three patients underwent re-do spinal surgery for CSF leak repair. Patients in all groups satisfactorily avoided CSF leak. According to the intraoperative findings of a distinct dural tear, patients can be treated adequately with a specific surgical technique.


Assuntos
Dura-Máter/lesões , Fístula/cirurgia , Procedimentos Neurocirúrgicos/métodos , Coluna Vertebral/cirurgia , Traumatismos do Sistema Nervoso/classificação , Traumatismos do Sistema Nervoso/cirurgia , Descompressão Cirúrgica/efeitos adversos , Discotomia/efeitos adversos , Dura-Máter/cirurgia , Fístula/etiologia , Humanos , Análise de Intenção de Tratamento , Adesivos Teciduais/uso terapêutico , Traumatismos do Sistema Nervoso/etiologia
11.
Curr Opin Anaesthesiol ; 32(5): 580-584, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31145200

RESUMO

PURPOSE OF REVIEW: This article reviews the recent outcome studies that investigated intraoperative neurophysiological monitoring (IONM) during spine, neurovascular and brain tumor surgery. RECENT FINDINGS: Several recent studies have focused on identifying which types of neurosurgical procedures might benefit most from IONM use. Despite conflicting literature regarding its efficacy in improving neurological outcomes, many experts have advocated for the use of IONM in neurosurgery. Several themes have emerged from the recent literature: the entire perioperative team must always work together to ensure adequate communication and intervention; systems and checklists, in which each member of the perioperative team has a clearly defined role, can be useful in the event of a sudden intraoperative changes in electrophysiological signals; regardless of the IONM modality used, any sudden change in electrophysiological signal should prompt an immediate and appropriate intervention; a multimodal IONM approach is often, but not always, advantageous over a single IONM approach. SUMMARY: For neurosurgical procedures that can be complicated by neural injury, the use of IONM should be considered according to specific patient and surgical factors. Future studies should focus on improving IONM technology and optimizing sensitivity and specificity for detecting any impending neural damage.


Assuntos
Anestesia/métodos , Complicações Intraoperatórias/diagnóstico , Monitorização Neurofisiológica Intraoperatória/métodos , Procedimentos Neurocirúrgicos/efeitos adversos , Traumatismos do Sistema Nervoso/diagnóstico , Anestesia/efeitos adversos , Neoplasias Encefálicas/cirurgia , Transtornos Cerebrovasculares/cirurgia , Medicina Baseada em Evidências/métodos , Humanos , Complicações Intraoperatórias/etiologia , Complicações Intraoperatórias/prevenção & controle , Procedimentos Neurocirúrgicos/métodos , Complicações Pós-Operatórias , Sensibilidade e Especificidade , Doenças da Coluna Vertebral/cirurgia , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/prevenção & controle , Resultado do Tratamento
12.
Int J Mol Sci ; 20(2)2019 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-30658442

RESUMO

Central nervous system (CNS) injury, such as stroke or trauma, is known to increase susceptibility to various infections that adversely affect patient outcomes (CNS injury-induced immunodepression-CIDS). The endocannabinoid system (ECS) has been shown to have immunoregulatory properties. Therefore, the ECS might represent a druggable target to overcome CIDS. Evidence suggests that cannabinoid type 2 receptor (CB2R) activation can be protective during the early pro-inflammatory phase after CNS injury, as it limits neuro-inflammation and, therefore, attenuates CIDS severity. In the later phase post CNS injury, CB2R inhibition is suggested as a promising pharmacologic strategy to restore immune function in order to prevent infection.


Assuntos
Doenças do Sistema Nervoso Central/metabolismo , Endocanabinoides/metabolismo , Traumatismos do Sistema Nervoso/metabolismo , Imunidade Adaptativa , Animais , Doenças do Sistema Nervoso Central/diagnóstico , Doenças do Sistema Nervoso Central/etiologia , Humanos , Imunidade Inata , Neuroimunomodulação , Transdução de Sinais , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/etiologia , Acidente Vascular Cerebral/metabolismo , Fatores de Tempo , Traumatismos do Sistema Nervoso/diagnóstico , Traumatismos do Sistema Nervoso/etiologia
13.
Methods Mol Biol ; 1938: 233-246, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30617984

RESUMO

Astrocytes are glial cells carrying out complex homeostatic functions in the healthy and diseased central nervous system (CNS). It has so far been impossible to reliably culture adult astrocytes and the results of studies on astrocytes outside of their normal environment are challenging to interpret. Consequently, most culture studies use astrocytes isolated from postnatal rodents. Yet cultured astrocytes do not display their complex three-dimensional in vivo morphology, and transcriptomes of cultured astrocytes vary significantly from those of acutely isolated astrocytes (Cahoy et al., J Neurosci 28:264-278, 2008). Astrocyte isolation for culture experiments, and the cutting of acute brain slices, induces astrocyte reactivity similar to a severe acute injury. In response to CNS injury, such as moderate or severe focal traumatic brain injury (TBI), astrocytes can change in cell number, physiological state, gene and protein expression, secretome, and morphology, in a process termed reactive astrogliosis. This makes the use of methods that inherently induce astrogliosis (e.g., dissociation of brain tissue for culture or sectioning of brains for acute brain slices) challenging, especially when conditions are studied that present with changes in astrocyte function that are milder and/or of a different nature.In this methods chapter, we will describe a technical approach that allows one to study astrocytes in the intact brain using two-photon in vivo imaging. We will use mild TBI as an example of how to use this approach to compare astrocyte function in the same animal before and after an injury.Here we describe the use of a noninvasive label-free method (Choi et al., J Biomed Opt 16:075003, 2011) to increase astrocyte Ca2+ using optical femtosecond pulsed laser activation. We will provide systematic instruction of the surgical technique, which when done properly, allows in vivo astrocyte imaging in the same experimental animal before the injury as well as over the course of days, weeks, and even months after injury. We will also elaborate on challenges in astrocytic Ca2+ imaging and how different image acquisition settings can affect the readout of astrocyte Ca2+ oscillations.


Assuntos
Astrócitos/metabolismo , Sistema Nervoso Central/metabolismo , Imagem Molecular , Traumatismos do Sistema Nervoso/metabolismo , Animais , Vasos Sanguíneos/metabolismo , Cálcio/metabolismo , Sinalização do Cálcio , Feminino , Processamento de Imagem Assistida por Computador , Masculino , Camundongos , Microscopia/métodos , Modelos Animais , Imagem Molecular/métodos , Imagem com Lapso de Tempo , Traumatismos do Sistema Nervoso/etiologia
14.
Handb Clin Neurol ; 158: 25-37, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30482353

RESUMO

Tens of millions of children and adults participate in organized sport in the United States each year. Although uncommon, fatal and severe nonfatal brain and spine injuries can occur during these activities. These "catastrophic" injuries have been noted in contact sports such as football, rugby, and ice hockey, as well as in noncontact sports including baseball, cheerleading, swimming and diving, equestrian, gymnastics, pole vault, rodeo, snow skiing, snowboarding, and wrestling. They happen at all levels of play, from youth to professional. Among all sports, football has the highest number of fatal brain and cervical spine injuries. While these injuries are more frequent in high school football, the rate is higher amongst college football athletes. Patterns exist in the types of brain and spine injuries most often occurring as a result of traumatic impacts in sport, but incidence and mechanisms of injury vary dramatically between sports. Understanding these patterns is essential to informing prevention efforts; football, pole vault, and cheer are all examples of sports benefiting from successful catastrophic injury prevention efforts. Participating in sport provides many benefits to physical and mental health. Despite these benefits, rare devastating injuries can be traumatic for the athletes, their families, and communities and can raise safety concerns that may reduce participation in sport. Understanding and preventing these types of injuries are critical to fostering participation in sport and ensuring both children and adults reap the physical, social, and mental benefits of sport.


Assuntos
Traumatismos em Atletas/complicações , Catastrofização , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/psicologia , Traumatismos em Atletas/epidemiologia , Humanos , Estados Unidos/epidemiologia
15.
J Cardiovasc Transl Res ; 11(6): 503-516, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30367354

RESUMO

Surgery on the arch or descending aorta is associated with significant risk of neurological complications. As a consequence of intubation and sedation, early neurologic injury may remain unnoticed. Biomarkers to aid in the initial diagnostics could prove of great value as immediate intervention is critical. Twenty-three patients operated in the thoracic aorta with significant risk of perioperative neurological injury were included. Cerebrospinal fluid (CSF) and serum were obtained preoperatively and in the first and second postoperative days and assessed with a panel of 92 neurological-related proteins. Three patients suffered spinal cord injury (SCI), eight delirium, and nine hallucinations. There were markers in both serum and CSF that differed between the affected and non-affected patients (SCI; IL6, GFAP, CSPG4, delirium; TR4, EZH2, hallucinations; NF1). The study identifies markers in serum and CSF that reflect the occurrence of neurologic insults following aortic surgery, which may aid in the care of these patients.


Assuntos
Aorta Torácica/cirurgia , Doenças da Aorta/cirurgia , Proteínas Sanguíneas/metabolismo , Proteínas do Líquido Cefalorraquidiano/líquido cefalorraquidiano , Proteômica/métodos , Traumatismos do Sistema Nervoso/diagnóstico , Procedimentos Cirúrgicos Vasculares/efeitos adversos , Idoso , Biomarcadores/sangue , Biomarcadores/líquido cefalorraquidiano , Delírio/sangue , Delírio/líquido cefalorraquidiano , Delírio/diagnóstico , Feminino , Alucinações/sangue , Alucinações/líquido cefalorraquidiano , Alucinações/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Fatores de Risco , Traumatismos da Medula Espinal/sangue , Traumatismos da Medula Espinal/líquido cefalorraquidiano , Traumatismos da Medula Espinal/diagnóstico , Traumatismos do Sistema Nervoso/sangue , Traumatismos do Sistema Nervoso/líquido cefalorraquidiano , Traumatismos do Sistema Nervoso/etiologia , Resultado do Tratamento
16.
Orthop Surg ; 10(2): 98-106, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29878716

RESUMO

OBJECTIVE: To analyze the early complications and causes of oblique lateral interbody fusion, and put forward preventive measures. METHODS: There were 235 patients (79 males and 156 females) analyzed in our study from October 2014 to May 2017. The average age was 61.9 ± 0.21 years (from 32 to 83 years). Ninety-one cases were treated with oblique lateral interbody fusion (OLIF) alone (OLIF alone group) and 144 with OLIF combined with posterior pedicle screw fixation through the intermuscular space approach (OLIF combined group). In addition, 137/144 cases in the combined group were primarily treated by posterior pedicle screw fixation, while the treatments were postponed in 7 cases. There were 190 cases of single fusion segments, 11 of 2 segments, 21 of 3 segments, and 13 of 4 segments. Intraoperative and postoperative complications were observed. RESULTS: Average follow-up time was 15.6 ± 7.5 months (ranged from 6 to 36 months). Five cases were lost to follow-up (2 cases from the OLIF alone group and 3 cases from the OLIF combined group). There were 7 cases of vascular injury, 22 cases of endplate damage, 2 cases of vertebral body fracture, 11 cases of nerve injury, 18 cases of cage sedimentation or cage transverse shifting, 3 cases of iliac crest pain, 1 case of right psoas major hematoma, 2 cases of incomplete ileus, 1 case of acute heart failure, 1 case of cerebral infarction, 3 case of left lower abdominal pain, 9 cases of transient psoas weakness, 3 cases of transient quadriceps weakness, and 8 cases of reoperation. The complication incidence was 32.34%. Thirty-three cases occurred in the OLIF alone group, with a rate of 36.26%, and 43 cases in the group of OLIF combined posterior pedicle screw fixation, with a rate of 29.86%. Fifty-seven cases occurred in single-segment fusion, with a rate of 30.0% (57/190), 4 cases occurred in two-segment fusion, with a rate of 36.36% (4/11), 9 cases occurred in three-segment fusion, with a rate of 42.86% (9/21), and 6 cases occurred in four-segment fusion, with a rate of 46.15% (6/13). CONCLUSION: In summary, OLIF is a relatively safe and very effective technique for minimally invasive lumbar fusion. Nonetheless, it should be noted that OLIF carries the risk of complications, especially in the early stage of development.


Assuntos
Vértebras Lombares/cirurgia , Fusão Vertebral/efeitos adversos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Complicações Intraoperatórias/etiologia , Complicações Intraoperatórias/prevenção & controle , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/lesões , Masculino , Pessoa de Meia-Idade , Debilidade Muscular/etiologia , Debilidade Muscular/prevenção & controle , Parafusos Pediculares , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/prevenção & controle , Radiografia , Fraturas da Coluna Vertebral/diagnóstico por imagem , Fraturas da Coluna Vertebral/etiologia , Fraturas da Coluna Vertebral/prevenção & controle , Fusão Vertebral/instrumentação , Fusão Vertebral/métodos , Tomografia Computadorizada por Raios X , Traumatismos do Sistema Nervoso/etiologia , Traumatismos do Sistema Nervoso/prevenção & controle , Lesões do Sistema Vascular/etiologia
17.
Medicine (Baltimore) ; 97(21): e10821, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29794770

RESUMO

To investigate the incidence and pattern of child and adolescent (≤18 years old) traumatic fractures (TFs) as a result of collisions.We retrospectively reviewed 270 child and adolescent patients (228 males and 42 females aged 12.8 ±â€Š5.1 years old) with TFs as a result of collisions admitted to our university-affiliated hospitals from 2001 to 2010. The incidence and patterns were summarized with respect to different age groups, sex, etiology, and whether the patient presented with nerve injury.The most common etiologies were struck by object (105, 38.9%) and wounded by person (74, 27.4%). The most common fracture sites were upper limb fractures (126, 46.7%) and craniofacial fractures (82, 30.4%). A total of 65 (24.1%) patients suffered a nerve injury. The frequency of early and late complications/associated injuries was 35.6% (n = 96) and 8.5% (n = 23), respectively. The mean age (P = .001) and frequency of wounded by person (P = .038) was significantly larger in male than in female patients. The frequency of earthquake injury (P < .001) and lower limb fractures (P = .002) was significantly larger in females than in male patients. The frequency of upper limb fracture was significantly higher in the wounded by machine group (83.3%) than in the other groups (all P < .05). The frequency of lower limb fractures was significantly higher in the earthquake injury group (64.7%) than in the other groups (all P < .05). The frequency of craniofacial fracture was significantly higher in the wounded by person group (54.1%) than in the other groups (all P < .05). The emergency admission rate (P = .047), frequency of wounded by person (P < .001), craniofacial fracture (P < .001), and early complications/associated injuries (P < .001) were significantly larger in patients with nerve injury than in other patients.Struck by object and upper limb fractures were the most common etiology and site, respectively. Wounded by person and craniofacial fractures were risk factors for nerve injury. Therefore, we should pay more attention to patients wounded by person, presenting with craniofacial fracture, to find whether there is nerve injury.


Assuntos
Ossos Faciais/lesões , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/etiologia , Extremidade Inferior/lesões , Traumatismos do Sistema Nervoso/complicações , Extremidade Superior/lesões , Adolescente , Criança , Ossos Faciais/patologia , Feminino , Fraturas Ósseas/complicações , Hospitalização/estatística & dados numéricos , Humanos , Incidência , Extremidade Inferior/patologia , Masculino , Estudos Retrospectivos , Fatores de Risco , Fraturas Cranianas/complicações , Fraturas Cranianas/epidemiologia , Fraturas Cranianas/patologia , Traumatismos do Sistema Nervoso/epidemiologia , Traumatismos do Sistema Nervoso/etiologia , Extremidade Superior/patologia
18.
Med Sci Monit ; 24: 782-790, 2018 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-29411738

RESUMO

BACKGROUND Although iatrogenic posterior interosseous nerve (PIN) palsy is an uncommon complication of ruptured distal biceps brachii tendon surgical anatomical reinsertion, it is the most severe complication leading to functional limitation. The present study investigated possible types of PIN palsy as a postoperative complication of anatomical distal biceps tendon reinsertion, and aimed to clinically assess patients at 2 years after its surgical treatment. MATERIAL AND METHODS The studied sample comprised 7 male patients diagnosed with an iatrogenic PIN palsies after anatomical reinsertion of the distal biceps tendon, who were referred to the reference center for management of a peripheral nervous system injury. The nerve injury was intraoperatively evaluated. The clinical assessment used the Medical Research Council (MRC) System for motor recovery, and the Quick Disability of the Arm, Shoulder, and Hand (Quick DASH) was performed before the surgical treatment of the PIN injuries and at 2 years postoperatively. In all studied cases, electromyography was performed preoperatively and postoperatively. RESULTS The comparison of the preoperative (x=1.43±0.53) and postoperative (x=4.71±0.49) results of the motor recovery of the PIN demonstrated a statistically significant improvement (p<0.001). Moreover, the results of functional assessments with the use of the Quick DASH questionnaire significantly improved (p<0.001) postoperatively (x=6.14±6.86) compared to the preoperative evaluations (x=54.29±12.05). CONCLUSIONS The PIN palsies as complications of the surgical anatomical reinsertion of ruptured distal biceps brachii resulted from mechanical nerve compression or direct intraoperative damage. The 2-year outcomes justified the clinical use of surgical management for iatrogenic PIN palsy.


Assuntos
Doença Iatrogênica , Complicações Pós-Operatórias/etiologia , Tendões/patologia , Tendões/cirurgia , Traumatismos do Sistema Nervoso/etiologia , Adulto , Humanos , Cuidados Intraoperatórios , Masculino , Pessoa de Meia-Idade
19.
Int Orthop ; 42(3): 625-630, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29372269

RESUMO

PURPOSE: We investigated the incidence and pattern of traumatic fractures resulting from motor vehicle collisions in a population of children and adolescents (≤18 years old) and to determine the risk factors for nerve injury. METHODS: We retrospectively reviewed 734 patients admitted to our university-affiliated hospitals from 2001 to 2010. RESULTS: This study enrolled 498 male (67.8%) and 236 female (32.2%) patients aged 10.9 ± 5.3 years old. The most common injuries were to pedestrians, and the most common fracture sites (438, 59.7%) were to lower extremities (n = 441, 60.0%). A total of 201 (27.4%) patients experienced a nerve injury. Univariate logistic regression analysis showed that age (P = 0.014), lower-extremity (P = 0.000), craniofacial (P = 0.000) and spinal (P = 0.000) fractures were risk factors for nerve injury. Multivariate logistic regression analysis indicated that craniofacial [odds ratio (OR) = 9.003, 95% confidence interval (CI) 5.159-15.711, P = 0.000)] and spinal (experiencedOR = 10.141, 95% CI: 4.649-22.121, P = 0.011) fractures were independent risk factors for nerve injury. CONCLUSIONS: Patients in the 15- to 18-years old group and drivers had the largest sex ratio and highest frequencies of both nerve injury and early complications. Craniofacial and spinal fractures were independent risk factors for nerve injury. It is therefore important to focus on these risk factors to determine the presence of a nerve injury so that early, timely diagnosis and targeted treatment can be provided.


Assuntos
Acidentes de Trânsito/estatística & dados numéricos , Fraturas Ósseas/epidemiologia , Traumatismos do Sistema Nervoso/epidemiologia , Adolescente , Criança , Pré-Escolar , China/epidemiologia , Feminino , Fraturas Ósseas/complicações , Humanos , Incidência , Masculino , Veículos Automotores , Estudos Retrospectivos , Fatores de Risco , Traumatismos do Sistema Nervoso/etiologia
20.
Eur J Orthop Surg Traumatol ; 28(4): 747-751, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29372328

RESUMO

Deltoid palsy is a classical contraindication for reverse shoulder arthroplasty (RSA). However, in cases associating axillary nerve palsy and rotator cuff tear or glenohumeral arthritis, few options remain. We present a case in which combining RSA with transfer of the pectoralis major and upper and middle trapezius transfer provided satisfactory results in a patient suffering of both an irreparable rotator cuff tear and a deltoid palsy.Level of evidence IV.


Assuntos
Artroplastia do Ombro/métodos , Músculo Deltoide/lesões , Paralisia/etiologia , Traumatismos do Sistema Nervoso/etiologia , Idoso , Axila/inervação , Humanos , Masculino , Paralisia/cirurgia , Amplitude de Movimento Articular/fisiologia , Ruptura/etiologia , Resultado do Tratamento
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