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1.
Medicine (Baltimore) ; 99(44): e22944, 2020 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-33126362

RESUMO

BACKGROUND: Excessive and prolonged uterine bleeding is an important obstacle for medical abortion to get popularized. Shenghua decoction (SHD) is widely used for treating uterine bleeding after early medical abortion. However, the clinical evidence is unclear. METHODS: Two researchers will dependently search literatures of SHD for the treatment of uterine bleeding after medical abortion from Web of Science, PubMed, Embase, and The Cochrane Library; traditional Chinese medicine databases; China National Knowledge Infrastructure (CNKI); Chinese Scientific Journal Database (VIP database); and Wan-Fang Database. These inclusive data of included studies will be conducted by RevMan V5.3 software. RESULTS: This systematic review and meta-analysis will provide a detailed summary of the current evidence related to the efficacy of SHD in treating uterine bleeding after early medical abortion, including the duration and volume of uterine bleeding, the medical abortion pain. CONCLUSION: This systematic review and meta-analysis will provide a detailed summary of the current evidence related to the efficacy of SHD in treating uterine bleeding after early medical abortion, REGISTRATION NUMBER:: PROSPERO CRD42020184465.


Assuntos
Aborto Induzido/efeitos adversos , Medicamentos de Ervas Chinesas/uso terapêutico , Hemorragia Uterina/tratamento farmacológico , Feminino , Humanos , Gravidez , Hemorragia Uterina/etiologia
5.
J Pregnancy ; 2020: 2856502, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33029400

RESUMO

Objectives: This study was aimed at assessing the magnitude of induced abortion and associated factors among students in Hawassa University, southern region, Ethiopia, 2019. Methods: An institutional-based cross-sectional study was conducted among a total of 422 students selected on the bases of a probability simple random sampling method. A pretested structured questionnaire was used to collect data. Analysis was made with SPSS 20. Descriptive summary and inferential statistics (binary logistic regression) were used with a 95% CI and P value of less than 5% as a level of significance. Findings were presented in tables, figure, and texts. Confidentiality of information was also secured. Results: The prevalence of induced abortion in the study setting was 68.7% (95% CI: 64.15%-73.2%). Participants who used emergency contraceptives had 12 times higher odds of undergoing abortion than those who did not use emergency contraceptives at AOR: 11.95, 95% CI: 5.615-25.326, P < 001. Conclusions: A higher prevalence of induced abortion was observed in the study setting. Contraceptive use was the predictor of induced abortion identified. Concerned bodies were recommended to work on the identified determinant of induced abortion in the study setting.


Assuntos
Aborto Induzido/estatística & dados numéricos , Anticoncepcionais/administração & dosagem , Estudantes/estatística & dados numéricos , Adolescente , Adulto , Estudos Transversais , Emergências , Etiópia/epidemiologia , Feminino , Humanos , Masculino , Valor Preditivo dos Testes , Prevalência , Inquéritos e Questionários , Adulto Jovem
8.
Sex Reprod Health Matters ; 28(3): 1831717, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33073725

RESUMO

In recent decades, bold steps taken by the government of Nepal to liberalise its abortion law and increase the affordability and accessibility of safe abortion and family planning have contributed to significant improvements in maternal mortality and other sexual and reproductive health (SRH) outcomes. The Trump administration's Global Gag Rule (GGR) - which prohibits foreign non-governmental organisations (NGOs) from receiving US global health assistance unless they certify that they will not use funding from any source to engage in service delivery, counselling, referral, or advocacy related to abortion - threatens this progress. This paper examines the impact of the GGR on civil society, NGOs, and SRH service delivery in Nepal. We conducted 205 semi-structured in-depth interviews in 2 phases (August-September 2018, and June-September 2019), and across 22 districts. Interview participants included NGO programme managers, government employees, facility managers and service providers in the NGO and private sectors, and service providers in public sector facilities. This large, two-phased study complements existing anecdotal research by capturing impacts of the GGR as they evolved over the course of a year, and by surfacing pathways through which this policy affects SRH outcomes. We found that low policy awareness and a considerable chilling effect cut across levels of the Nepali health system and exacerbated impacts caused by routine implementation of the GGR, undermining the ecology of SRH service delivery in Nepal as well as national sovereignty.


Assuntos
Aborto Induzido/economia , Aborto Induzido/legislação & jurisprudência , Serviços de Planejamento Familiar/economia , Serviços de Planejamento Familiar/legislação & jurisprudência , Saúde Global , Política , Desenvolvimento Econômico , Feminino , Regulamentação Governamental , Direitos Humanos , Humanos , Internacionalidade , Entrevistas como Assunto , Nepal , Estados Unidos
10.
Medicine (Baltimore) ; 99(42): e22533, 2020 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-33080687

RESUMO

RATIONALE: Split-hand/split-foot malformation (SHFM), also known as ectrodactyly, is a congenital limb malformation affecting the central rays of the autopod extending to syndactyly, median clefts of the hands and feet, aplasia/hypoplasia of phalanges, metacarpals and metatarsals. Duplication of this 10q24 region is associated with SHFM3. While the clinical and genetic heterogeneity of SHFM makes the prenatal diagnosis and genetic counseling more challenging and difficult. PATIENT CONCERNS: A physically normal pregnant woman had a systemic ultrasound at the second trimester, only identified the deformity of both hands and feet on the fetus. DIAGNOSES: The fetus was diagnosed as sporadic SHFM3. INTERVENTIONS: After seeking advice from genetic counseling, she decided to terminate the pregnancy. The induction of infant was done after appearance of bipedal clefts, lobster-claw appearance and partial loss of phalanges and metacarpals, leaving behind 2nd finger in the left hand and the 5th in the right hand. Furthermore, collection of umbilical cord is recommended to this fetus for genome-wide detection. OUTCOMES: An outcome of the gene detection from abortion shows that there is variation in copy number in genome of chromosome 1 and chromosome 10. LESSONS: This case study confirms an association between SHFM3 and chromosomal micro-duplication on 10q24.3, and the extension of clinical spectrum of SHFM3. It also proposes some prenatal diagnosis and genetic counseling to help in planning and management in affected pregnancy. This will reduce the congenital and development abnormalities in birth rate, as well as relive the economic, psychological, and physical burden to the affected families.


Assuntos
Aconselhamento Genético , Deformidades Congênitas dos Membros/diagnóstico , Deformidades Congênitas dos Membros/genética , Diagnóstico Pré-Natal , Aborto Induzido , Duplicação Cromossômica , Feminino , Humanos , Gravidez
12.
PLoS Med ; 17(9): e1003333, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32925909

RESUMO

BACKGROUND: Long-acting reversible contraception (LARC) is among the most effective contraceptive methods, but uptake remains low even in high-income settings. In 2009/2010, a target-based pay-for-performance (P4P) scheme in Britain was introduced for primary care physicians (PCPs) to offer advice about LARC methods to a specified proportion of women attending for contraceptive care to improve contraceptive choice. We examined the impact and equity of this scheme on LARC uptake and abortions. METHODS AND FINDINGS: We examined records of 3,281,667 women aged 13 to 54 years registered with a primary care clinic in Britain (England, Wales, and Scotland) using Clinical Practice Research Datalink (CPRD) from 2004/2005 to 2013/2014. We used interrupted time series (ITS) analysis to examine trends in annual LARC and non-LARC hormonal contraception (NLHC) uptake and abortion rates, stratified by age and deprivation groups, before and after the P4P was introduced in 2009/2010. Between 2004/2005 and 2013/2014, crude LARC uptake rates increased by 32.0% from 29.6 per 1,000 women to 39.0 per 1,000 women, compared with 18.0% decrease in NLHC uptake. LARC uptake among women of all ages increased immediately after the P4P with step change of 5.36 per 1,000 women (all values are per 1,000 women unless stated, 95% CI 5.26-5.45, p < 0.001). Women aged 20 to 24 years had the largest step change (8.40, 8.34-8.47, p < 0.001) and sustained trend increase (3.14, 3.08-3.19, p < 0.001) compared with other age groups. NLHC uptake fell in all women with a step change of -22.8 (-24.5 to -21.2, p < 0.001), largely due to fall in combined hormonal contraception (CHC; -15.0, -15.5 to -14.5, p < 0.001). Abortion rates in all women fell immediately after the P4P with a step change of -2.28 (-2.98 to -1.57, p = 0.002) and sustained decrease in trend of -0.88 (-1.12 to -0.63, p < 0.001). The largest falls occurred in women aged 13 to 19 years (step change -5.04, -7.56 to -2.51, p = 0.011), women aged 20 to 24 years (step change -4.52, -7.48 to -1.57, p = 0.030), and women from the most deprived group (step change -4.40, -6.89 to -1.91, p = 0.018). We estimate that by 2013/2014, the P4P scheme resulted in an additional 4.53 LARC prescriptions per 1,000 women (relative increase of 13.4%) more than would have been expected without the scheme. There was a concurrent absolute reduction of -5.31 abortions per 1,000 women, or -38.3% relative reduction. Despite universal coverage of healthcare, some women might have obtained contraception elsewhere or had abortion procedure that was not recorded on CPRD. Other policies aiming to increase LARC use or reduce unplanned pregnancies around the same time could also explain the findings. CONCLUSIONS: In this study, we found that LARC uptake increased and abortions fell in the period after the P4P scheme in British primary care, with additional impact for young women aged 20-24 years and those from deprived backgrounds.


Assuntos
Contracepção Reversível de Longo Prazo/psicologia , Contracepção Reversível de Longo Prazo/tendências , Reembolso de Incentivo/tendências , Aborto Induzido , Aborto Espontâneo , Adolescente , Adulto , Anticoncepção/métodos , Anticoncepcionais Femininos , Feminino , Humanos , Análise de Séries Temporais Interrompida/métodos , Contracepção Reversível de Longo Prazo/economia , Pessoa de Meia-Idade , Gravidez , Gravidez não Planejada , Atenção Primária à Saúde , Reino Unido , Adulto Jovem
14.
J Law Med ; 27(4): 928-936, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32880410

RESUMO

The abortion drug RU 486 is widely available across the developed world, and its benefits and efficacy for women have been well established over the 40 years since its development. However, access to RU 486 for women in Australia has been a vexed issue since the mid-1990s. Because of pro-life politics under the Howard Government, importation of the drug into Australia was severely hampered, resulting in Australia lagging behind the rest of the developed world in access to medical abortions. This article highlights the history of RU 486, the current state of abortion laws in Australia and the issues that the politics of the 1990s still cause for Australian women who seek a medical abortion (especially those living remotely). Finally, it proposes some options that could alleviate some of the difficulties faced by those who seek access to RU 486.


Assuntos
Aborto Induzido , Mifepristona , Austrália , Feminino , Humanos , Princípios Morais , Política , Gravidez
18.
Medicine (Baltimore) ; 99(39): e22499, 2020 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-32991490

RESUMO

INTRODUCTION: The clinical treatment is complicated for patients with placenta previa who must terminate pregnancy due to fetal malformation, death, or inevitable abortion in the second trimester. It is difficult to manage excessive bleeding during pregnancy termination; and those patients face risks of removing the uterus, infection and other complications. PATIENT CONCERNS: Two patients had placenta previa in the second trimester. Both cases had to terminate pregnancy. Case 1 patient had intrauterine fetal death. Case 2 patient had life-threatening vaginal bleeding. Both patients had bleeding and their cervix was not mature during vaginal delivery. DIAGNOSIS: After hospitalization, placenta previa was confirmed by magnetic resonance imaging for case 1 patient. Placenta previa was confirmed by ultrasound examination for case 2 patient. Both patients had to terminate pregnancy. INTERVENTIONS: We designed a new procedure using a cervical ripening balloon to reduce the risks during pregnancy termination for patients with placenta previa. A cervical ripening balloon was inserted through the placenta and placed between the fetus and placenta; external force was applied to keep the cervical ripening balloon pressing against the placenta that covers the cervical os. The cervical ripening balloon dilated the cervix, quickly reduced bleeding, and induced vaginal delivery during pregnancy termination for patients with placenta previa. This method was applied to 2 patients with placenta previa who must terminate pregnancy. OUTCOMES: Using the new method, both patients had a successful pregnancy termination and vaginal delivery with minimal bleeding. Total time from the balloon placement to the end of the delivery was about 3 hours. The procedure only used a cervical ripening balloon without uterine artery embolization needed. The fetus was delivered through the vagina; and the uterus was fully retained. There was no postpartum infection. CONCLUSION: This new method using a cervical ripening balloon could be a quick and effective way to reduce the risks during pregnancy termination for patients with placenta previa. It is especially helpful in emergency situations with minimal requirements of personnel and equipment. Our study showed great potential of this new utilization of a cervical ripening balloon, and is worthy of further research.


Assuntos
Aborto Induzido , Técnicas Hemostáticas/instrumentação , Placenta Prévia , Hemorragia Uterina/terapia , Adulto , Feminino , Morte Fetal , Humanos , Gravidez , Segundo Trimestre da Gravidez
19.
J. Hum. Growth Dev. (Impr.) ; 30(2): 170-178, May-Aug. 2020. tab
Artigo em Inglês | LILACS, Index Psicologia - Periódicos técnico-científicos | ID: biblio-1114925

RESUMO

INTRODUCTION: Unwanted pregnancy is a serious consequence for women who experience sexual violence. Although deciding on abortion is frequent in these cases, there is not much information on women who give up abortion in this circumstanceOBJECTIVE: To analyse the associated factors in abortion withdrawal of sexual violence pregnancyMETHODS: A cross-sectional epidemiological study with a convenience sample of adolescents and women with pregnancy due to sexual violence and requesting legal abortion between August 1994 and December 2012, at Hospital Pérola Byington, São Paulo, Brazil. Pregnant women who gave up abortion after receiving the procedure approval were included and, in another group, pregnant women who completed the abortion. The variables were selected from a digitized database and analyzed using SPSS 15.0 software. The outcome was abortion withdrawal. The study variables were age; low education level; gestational age; color/black ethnicity; not being united; declare religion; serious threat from the aggressor; known offender; and residence of the aggressor. Odds ratios with 95% confidence intervals were calculated. The analysis used Wald's chi-square test (χ2W) and logistic regression with variable of interest defined as the known aggressor. The research was approved by the Research Ethics Committee of the Federal University of São Paulo, Opinion No. 6767RESULTS: The study included 941 women, 849 (90.2%) who had an abortion and 92 (9.8%) who gave up after being approved. Age ranged from 10-46 years, mean 23.2 ± 7.9 years, gestational age 4-22 weeks, average 11.9 ± 4.5 weeks. Among those who gave up abortion, 12.0% were <14 years old; 50.0% had gestational age ≥ 13 weeks; 50.0% had low education; 14.2% were black; 90.2% single; 85.9% declared to have religion; 50.0% were threatened; 12.0% of the cases occurred at the perpetrator's residence and 53.3% of the victims were raped by known perpetrators. In logistic regression, the only significant variable was the known perpetrator, increasing the victim's chance of giving up abortion twiceCONCLUSION: The known sex offender has influenced the woman or adolescent's decision to give up legal abortion


INTRODUÇÃO: A gravidez forçada é uma grave consequência para mulheres que sofrem violência sexual. Embora decidir pelo aborto seja frequente nestes casos, há escassa informação sobre as mulheres que desistem de realizar ao aborto nessa circunstânciaOBJETIVO: Analisar os fatores associados na desistência do abortamento de gestação decorrente de violência sexualMÉTODO: A cross-sectional epidemiological study com amostra de conveniência de adolescentes e mulheres com gravidez decorrente de violência sexual e solicitação de aborto legal entre agosto de 1994 e dezembro de 2012, no Hospital Pérola Byington, São Paulo, Brasil. Foram incluídas gestantes que desistiram de realizar o aborto após receberem aprovação do procedimento e, em outro grupo, as gestantes que concluíram o aborto. As variáveis foram selecionadas de banco de dados digitalizado e analisadas em software SPSS 15.0. O desfecho foi desistência do aborto. As variáveis de estudo foram a idade, baixa escolaridade; idade gestacional; cor/etnia negra; não estar unida; declarar religião; grave ameaça do agressor; agressor conhecido; e residência do agressor. Foram calculadas as razões de chances (Odds Ratio) com intervalo de confiança de 95%. A análise utilizou teste de qui-quadrado de Wald (χ2W) e regressão logística com variável de interesse definida como o agressor conhecido. A pesquisa recebeu aprovação do Comitê de Ética e Pesquisa da Universidade Federal de São Paulo, Parecer nº 6767RESULTADOS: O estudo contou com 941 mulheres, sendo 849 (90,2%) que realizaram o aborto e 92 (9,8%) que desistiram após receberem aprovação. A idade variou de 10-46 anos, média 23,2±7,9 anos, com idade gestacional de 4-22 semanas, média 11,9±4,5 semanas. Entre as que desistiram do aborto, 12,0% tinham idade < 14 anos; 50,0% apresentaram idade gestacional ≥ 13 semanas; 50,0% tinham baixa escolaridade; 14,2% eram negras; 90,2% solteiras; 85,9% declararam ter religião; 50,0% sofreram ameaça; 12,0% dos casos ocorreram na residência do agressor e 53,3% das vítimas foram violentadas por agressores conhecidos. Na regressão logística, a única variável significante foi o agressor conhecido, aumentando em duas vezes a chance da vítima de desistir do abortoCONCLUSÃO: O agressor sexual conhecido exerceu influência na decisão da mulher ou adolescente de desistir do aborto legal


Assuntos
Humanos , Feminino , Gravidez , Adolescente , Delitos Sexuais , Aborto Induzido , Aborto Legal , Violência Doméstica , Mulheres Maltratadas
20.
Adv Exp Med Biol ; 1252: 153-157, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32816276

RESUMO

Cancer associated with pregnancy is defined by diagnosis during pregnancy, lactation, or the first year after delivery. The decision about type of treatment depends on the cancer stage and gestational age. Termination of pregnancy does not seem to modify the maternal prognosis for breast cancers. Interdisciplinary meetings and discussions are needed to evaluate and balance the maternal and fetal risks. In this chapter, we discuss about how to prevent or treat maternal and fetal complications of surgery and chemotherapy in pregnancy-associated breast cancer.


Assuntos
Complicações Neoplásicas na Gravidez/terapia , Cuidado Pré-Natal/métodos , Aborto Induzido , Tomada de Decisão Clínica , Feminino , Idade Gestacional , Humanos , Lactação , Estadiamento de Neoplasias , Gravidez
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