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1.
J Drugs Dermatol ; 21(1): 49-53, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-35005859

RESUMO

Alopecia or hair loss in children is an important and often challenging problem to diagnose and treat. Early diagnosis and treatment is the key because hair loss in children has a significant physical as well as psychological impact on their development. Alopecia in children are mainly non-scarring, but cicatricial alopecia can also be seen. The diagnosis can usually be made by direct examination of the scalp. Potassium hydroxide (KOH) examination of plucked hair and scalp scrapings, woods lamp examination and trichoscopy are useful diagnostic aids. When a cicatricial alopecia is suspected, scalp biopsy is recommended. Disease specific treatment should be initiated early and adequate counselling provided to both the patient and their parents. This review focuses on the treatment options available for various types of alopecia in children and their safety and efficacy data, analyzing the available literature evidences. J Drugs Dermatol. 2022;21(1):49-53. doi:10.36849/JDD.6096.


Assuntos
Alopecia , Cabelo , Alopecia/patologia , Biópsia , Criança , Cicatriz/patologia , Humanos , Couro Cabeludo/patologia
2.
J Dermatol ; 49(1): 3, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34978730

Assuntos
Cabelo , Humanos
3.
J Environ Manage ; 302(Pt A): 114029, 2022 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-34872177

RESUMO

Accumulation of hair waste is a major burden to the leather industry, causing a negative impact on the industry's sustainable development. The industry is already bogged down by the usage of synthetic re-tanning agents that are not only extremely challenging for biodegradation but also release free-form of formaldehyde in the final leather stage. This research work focuses on developing a formaldehyde-free bio-based re-tanning agent from hair waste. In order to do so, hair waste is subjected to alkali hydrolysis and subsequently graft-copolymerized with methacrylic acid (MAA). These treatments were optimal using 20 % (w/w) sodium hydroxide and thermal activity at 90 °C. This resulted in effective hydrolysis of red sheep hair, which was the ideal candidate in this study. The hydrolysate was subjected to monomer in situ polymerization (using MAA) with potassium per sulfate/sodium meta-bisulphite redox system, leading to the development of keratin hydrolysate-g-methacrylic acid (KH-g-MA) copolymer (this was noted both at a laboratory level and pilot scale). The obtained KH-g-MA copolymer exhibited ideal characteristics such as increased protein content (78.3 ± 1.2), appropriate particle size (1516 nm), suitable pH (5) and required viscosity of 512 cP. The developed KH-g-MA copolymer was then applied as a re-tanning agent in the leather manufacturing process. Significant improvement in leather's mechanical strength characteristics was observed. In addition, the organoleptic properties of leather such as fullness, softness and grain tightness showed much improvement. Scanning electron microscopy (SEM) showed an enhanced surface smoothness and filling of the voids in experimental leather in comparison to the control leather. This recycle and reuse strategy of hair waste not only helps resolve issues with handling of hair solid waste but also results in producing an eco-friendly re-tanning agent in leather manufacturing, thereby paving the way for cyclic economic utilization and cleaner environment.


Assuntos
Cabelo , Curtume , Animais , Biodegradação Ambiental , Hidrólise , Ovinos , Resíduos Sólidos
4.
Chemosphere ; 286(Pt 3): 131658, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34416585

RESUMO

Analysis of hair is known to provide useful information about environmental and toxic exposures. Very little historical use has been made of this type of investigation. Here we study 138 human hair samples from 19th century in France. In order to examine the potential association between contamination and historical health impacts, we characterized contamination by 33 elements in a set of hair strands sampled during the last quarter of the 19th century in the Savoy region of France. After a selected washing step on 138 hair strands conserved at the Museum National d'Histoire Naturelle in Paris (France), we assessed the presence of inorganics by ICP/MS, and lead level was higher than values reported in literature. We then compared concentrations and distributions between women and men, sampling locations and crossing gender and geographical origin. Hair lead level was high throughout Savoy at the end of the 19th century: significantly higher for people living in towns or industrial valleys, and lower for those of countryside and mountains areas. Environmental and economic changes (industrialization and urbanization with water adduction and leaded paints), living habits (kitchenware, cosmetics, wine, and tobacco), and local features (mines exploitation, railroad development, and industrialized narrow valleys) could be envisaged for explaining the level of lead contamination. In the same period, the two main industrial valleys of Savoy (Maurienne and Tarentaise) had high rates of endemic goiter and cretinism and among the highest hair lead levels. Other lines of evidence will need to be explore to investigate a possible link between historical Pb exposure and goiter in the study area.


Assuntos
Cabelo , Chumbo , Feminino , França , Cabelo/química , Humanos , Indústrias , Chumbo/análise , Masculino , Urbanização
5.
Sci Total Environ ; 806(Pt 3): 151352, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-34728202

RESUMO

Natural variations of 87Sr/86Sr ratios in biological samples, such as human hair, provide a biological record of provenance. Spatial distribution maps reflecting heterogeneity in isotopic signatures across large geographical regions are helpful for discerning the provenance and mobility of organisms. In this national-scale study conducted across South Korea, we investigated the spatial distribution patterns of 87Sr/86Sr ratios in human hair and tap water samples to determine their spatial variabilities and the relationships of isotopic signatures between hair and tap water. The strontium isoscapes of tap water and hair showed similar spatial distribution patterns. Non-parametric comparison indicated no significant differences in isotopic ratios between the two sample types. The 87Sr/86Sr ratios in human hair showed a significant and strong correlation with the ratios in tap water in eastern Korea, suggesting potential use of 87Sr/86Sr ratios in provenance studies. However, tap water and hair samples from western Korea did not show significant correlation between them, overall reducing the predictive power of the hair 87Sr/86Sr ratios for provenance studies. The deviation between 87Sr/86Srtap water and 87Sr/86Srhair was much larger in western coastal areas than in eastern Korea. Relatively high utilization of groundwater or exogenous materials, such as Asian dust, may have been responsible for this pattern. To fully utilize the potential of the strontium isotope signature as a biorecorder in provenance studies, it is essential to evaluate the effects of groundwater and other exogenous materials on the isotope signatures of hair and other biological samples. In this study, only hair samples from males were used to develop 87Sr/86Sr isoscapes. Therefore, further studies are required to examine the applicability of 87Sr/86Sr hair isoscapes based solely on human hair samples from males to forensic and provenance studies of human hair samples from females.


Assuntos
Isótopos de Estrôncio , Água , Feminino , Cabelo , Humanos , Isótopos , Masculino , Estrôncio
6.
Clin Dermatol ; 39(6): 1046-1062, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34920823

RESUMO

Sir Erasmus Wilson was a pioneer in dermatology and one of the most famous doctors in Victorian England. He enjoyed a sterling professional reputation, with one exception. During the 1860s, his name appeared in a wide variety of cosmetic advertisements endorsing commercial products such as Pears soap, which is still marketed today, as well as hair washes and pomades. Questions were raised in The Lancet about the propriety of Wilson's involvement with such commercial products. Wilson denied in a letter to The Lancet any connection with these advertisements; nonetheless, some confusion has lingered over the years about whether Wilson received any financial compensation from the Pears Soap Company in return for his product endorsements, and whether he enjoyed a business relationship with cosmetic companies that added to his wealth. This contribution presents a comprehensive review of Erasmus Wilson's relationship with cosmetic companies and his struggle to distance himself from them.


Assuntos
Sabões , Solo , Publicidade , Inglaterra , Cabelo , Humanos , Masculino
7.
Nutrients ; 13(12)2021 Nov 24.
Artigo em Inglês | MEDLINE | ID: mdl-34959769

RESUMO

The study aimed to explore the effects of fortified fermented rice-acid on the antioxidant capacity of mouse serum and the gut microbiota. Hair characteristics, body mass index, intestinal villus height, intestinal crypt depth, serum antioxidant capacity, and gut microbiota of mice were first measured and the correlation between the antioxidant capacity of mouse serum and the gut microbiota was then explored. The mice in the lactic acid bacteria group (L-group), the mixed bacteria group (LY-group), and the rice soup group (R-group) kept their weight well and had better digestion. The mice in the L-group had the better hair quality (dense), but the hair quality in the R-group and the yeast group (Y-group) was relatively poor (sparse). In addition, the inoculation of Lactobacillus paracasei H4-11 (L. paracasei H4-11) and Kluyveromyces marxianus L1-1 (K. marxianus L1-1) increased the villus height/crypt depth of the mice (3.043 ± 0.406) compared to the non-inoculation group (R-group) (2.258 ± 0.248). The inoculation of L. paracasei H4-11 and K. marxianus L1-1 in fermented rice-acid enhanced the blood antioxidant capacity of mouse serum (glutathione 29.503 ± 6.604 umol/L, malonaldehyde 0.687 ± 0.125 mmol/L, catalase 15.644 ± 4.618 U/mL, superoxide dismutase 2.292 ± 0.201 U/mL). In the gut microbiota of L-group and LY-group, beneficial microorganisms (Lactobacillus and Blautia) increased, but harmful microorganisms (Candidatus Arthromitus and Erysipelotrichales) decreased. L. paracasei H4-11 and K. marxianus L1-1 might have a certain synergistic effect on the improvement in antibacterial function since they reduced harmful microorganisms in the gut microbiota of mice. The study provides the basis for the development of fortified fermented rice-acid products for regulating the gut microbiota and improving the antioxidant capacity.


Assuntos
Antioxidantes/metabolismo , Alimentos Fortificados , Microbioma Gastrointestinal/fisiologia , Oryza/química , Animais , Índice de Massa Corporal , Cabelo/metabolismo , Mucosa Intestinal/metabolismo , Camundongos
8.
Harefuah ; 160(11): 721-723, 2021 Nov.
Artigo em Hebraico | MEDLINE | ID: mdl-34817136

RESUMO

INTRODUCTION: Hair tourniquet syndrome, AKA hair thread tourniquet or hair strangulation occurs among infants. A human hair or a thread strangulates a body appendage, resulting in obstruction of blood and lymph flow. If not recognized early it may cause tissue necrosis and rarely, require amputation. AIMS: Revealing the discrepancy between incidence and documentation in practice. Understanding the challenges standing in the way of the clinician while admitting a patient. METHODS: A retrospective study. The hospital's archive was searched for the period between the years 2008 to 2018. According to the ICD9 system this phenomenon is termed "external constriction caused by hair". Upon questioning, doctors had admitted having trouble finding the right diagnosis while digitally documenting a patient. The archive was searched twice - firstly, by the correct ICD9 code. Secondly, a general search was performed reviewing all 0-1 year-old patients' files. RESULTS: By researching the ICD9 code, 7 files were found. On the second search, 41 files were found, among them only 5 files were documented properly according to the ICD9 system. CONCLUSIONS: The majority (87.8%) of patients suffered from hair strangulation syndrome were not documented properly. Lack of documentation is a result of the digital difficulty finding the right diagnosis. DISCUSSION: Hair strangulation syndrome is not as rare as may be concluded basing on existing data. Clinicians must include it in the differential diagnosis when admitting a patient with the relevant symptoms or an agitated infant with no clear cause. Adjusting the digital systems in Israeli hospitals should be considered.


Assuntos
Cabelo , Torniquetes , Documentação , Humanos , Incidência , Lactente , Recém-Nascido , Isquemia , Estudos Retrospectivos
9.
Clin Dermatol ; 39(5): 809-818, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34785008

RESUMO

Healthy hair results from a combination of good generalized health and mindful health care practices. Many nutritional deficiencies lead to poor hair health and include changes to hair structure, texture, and viability. Although the mechanisms by which individual nutrients contribute to hair growth and maintenance have yet to be fully resolved, there are a variety of risk factors that predispose an individual to a nutritional deficiency; age, malnutrition, malabsorption, and medication use are among the most common. A thorough history should be taken in a patient with a hair disturbance to identify risk factors for a nutritional deficiency, which will then guide directed laboratory testing and treatment.


Assuntos
Desnutrição , Estado Nutricional , Cabelo , Humanos , Desnutrição/complicações
10.
Clin Dermatol ; 39(4): 738-742, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34809785

RESUMO

The complete or partial meeting of medial eyebrows at midline above the bridge of nose, forming a single band of hair, is known as synophrys or unibrow. With a few rare exceptions, when it may serve as a cutaneous marker lesion of several genetic disorders, with Cornelia De Lange syndrome being the commonest, synophrys is usually a normal variation. Although various cultures have prized synophrys as an attractive physical trait throughout history, in modern Western culture, the unibrow is frequently regarded as an undesirable and unappealing feature with negative connotations. Synophrys, derived from the Ancient Greek σύν (together, with) and ὀφρύς (eyebrow), meaning "with meeting eyebrows," refers to the complete or partial fusion of medial eyebrows at midline. The hair above the nasal bridge is often of the same color and thickness as the eyebrows, thus giving the appearance that they converge to form one uninterrupted line of hair, a single eyebrow.


Assuntos
Sobrancelhas , Nariz , Cabelo , Humanos , Fenótipo
11.
Fa Yi Xue Za Zhi ; 37(4): 479-485, 2021 Aug.
Artigo em Chinês | MEDLINE | ID: mdl-34725999

RESUMO

Abstract: Objective To establish a detection method for common new psychoactive substances of synthetic cannabinoids in hair with ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Methods In the 1 mL of internal standard methanol solution, 20 mg hair was added. After cryogenic grinding and ultrasonic extraction, the extract was separated by ACQUITY UPLC HSS T3 column (100 mm×2.1 mm, 1.8 µm). The mobile phase A was aqueous solution that composed of 20 mmol/L ammonium acetate, 0.1% formic acid, and 5% acetonitrile. The mobile phase B was acetonitrile. Electrospray ionization source in positive ion mode was used for data acquisition in multi-reaction monitoring (MRM) mode. Results The seven common new psychoactive substances of synthetic cannabinoids in hair had a good linear relationship within their respective linear ranges (r>0.99), the limits of detection were 0.5-2 pg/mg, the limits of quantification were 1-5 pg/mg, the intra-day and inter-day precisions were 0.1%-12.6%, the intra-day and inter-day accuracies were 89.2%-110.7%, the recovery rates were 52.3%-93.3%, and the matrix effects were 19.1%-95.2%. Conclusion The established method has a simple sample preparation process and high sensitivity. It is suitable for qualitative and quantitative analysis of common new psychoactive substances of synthetic cannabinoids in hair.


Assuntos
Canabinoides , Espectrometria de Massas em Tandem , Cromatografia Líquida de Alta Pressão , Cromatografia Líquida , Cabelo
12.
J Craniofac Surg ; 32(8): e790-e792, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34727457

RESUMO

ABSTRACT: Cosmetics with unknown chemical components may cause unexpected cancers. Here, we report a rare case of hair dye-induced intracranial communicating scalp sebaceous carcinoma in a young female who dyed her hair 10 years ago. The histological origin of the intracranial communicating neoplasm was of priority for subsequent therapeutic decisions, therefore, requiring comprehensive diagnostic strategy. In conclusion, this case report emphasizes careful evaluation of the long-term risks for unlabeled cosmetics.


Assuntos
Cosméticos , Tinturas para Cabelo , Neoplasias , Feminino , Cabelo , Humanos , Couro Cabeludo
13.
Int Breastfeed J ; 16(1): 75, 2021 10 07.
Artigo em Inglês | MEDLINE | ID: mdl-34620189

RESUMO

BACKGROUND: One of the most important protective health factors for children is breast-feeding, but the mechanisms for this effect are not fully elucidated. Our objective was to assess if the duration of breastfeeding influences cortisol in hair, used as a biomarker for stress in children still at school-age. METHODS: ABIS (All Babies in Southeast Sweden) is a prospective population-based child cohort study of 17,055 children born Oct 1st1997- Oct 1st 1999, with the aim to study development of immune-mediated diseases. Questionnaires were answered at birth and then at regular follow-ups, and biological samples were collected. As a biomarker of stress, we measured the child's cortisol in hair collected at 8 years of age, those randomly selected N = 126 children among those with enough hair samples for analyses of hair at 8 years of age. Duration of breastfeeding had been registered as well as psycho-social factors related to breastfeeding and/or stress. RESULTS: There was a negative correlation (r = - 0.23, p = 0.01) between total duration of breastfeeding and hair cortisol levels at 8 years of age. In a multivariate analysis this association persisted (p = 0.01) even when adjusted for other potential intervening factors like age of mother at delivery and early psychosocial vulnerability in the family, an index based on 11 factors (Multivariate model: df = 5, adj R2 = 0.15, F = 5.38, p < 0.01). CONCLUSION: Our results show that longer breastfeeding is associated with lower cortisol levels in the child many years later. These associations should be more elaborated in further studies, and these findings also give some implications for public health. Mothers should be encouraged to breastfeed their children also in the modern society, since breastfeeding promotes health in the child. This information could be given via the obstetric departments and later at the well-baby clinics.


Assuntos
Aleitamento Materno , Hidrocortisona , Criança , Estudos de Coortes , Feminino , Cabelo , Humanos , Lactente , Recém-Nascido , Gravidez , Estudos Prospectivos
14.
J Med Primatol ; 50(6): 306-312, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34622472

RESUMO

BACKGROUND: In captive colonies, owl monkeys' mothers sometimes reject their newborns. To prevent, mortality infants are manually raised by veterinarians. Both parental separation and rejection are stressful experiences, associated with elevated stress, physical, and behavioural disorders. The effect of parental deprivation in IVITA's owl monkeys stress profiles and health is unknown. METHODS: We compared stress biomarkers such as hair cortisol (using cortisol ELISA), stereotypic behaviours (with infrared cameras), and infection histories in juveniles separated from parents soon after birth (n = 14, ~17 months) and controls (n = 11, ~17 months). RESULTS: Parentally deprived owl monkeys show higher infection rates than controls (p = .001). However, they display no higher incidence of biomarkers of stress: Neither stereotypic behaviour nor cortisol in hair was different between cohorts. Irrespective of deprivation status, rates of infection, and concentration of cortisol in hair were positively associated (R2 = .29, p = .005). CONCLUSION: Early parental deprivation and natural high levels of cortisol secretion are associated with elevated infection levels in the IVITA owl monkey juveniles detectable up to 17 months post separation.


Assuntos
Aotidae , Hidrocortisona , Animais , Biomarcadores , Cabelo
15.
Natl Med J India ; 34(2): 108-110, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34599125
16.
J Nepal Health Res Counc ; 19(2): 425-427, 2021 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-34601544

RESUMO

Hair tourniquet syndrome is the strangulation of body appendages by a thread of hair. If neglected, it results in lymphatic obliteration, venous congestion, and arterial obstruction. A 25 years lady with a history of insect bite presented with intense itching and painful swelling in the left labia minora for three days. She had tied the swollen part with a bunch of hair strands leading to painful swelling. Local inspection revealed a 2x2 cm swelling in the left labia minora. The tourniquet effect was released by cutting the hair. Hair tourniquet syndrome involving female genitalia requires immediate recognition and treatment. Keywords: Hair tourniquet syndrome; hair-thread tourniquet syndrome; labia minora.


Assuntos
Torniquetes , Vulva , Adulto , Feminino , Cabelo , Humanos , Nepal , Síndrome
17.
J Eur Acad Dermatol Venereol ; 35 Suppl 2: 12-20, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34668237

RESUMO

BACKGROUND: Telogen effluvium is a hair loss disorder occurring about 3 months after a triggering event. The acute form impairs quality of life, but spontaneous recovery usually begins 3-6 months after identification and elimination of the cause, with complete recovery taking around 12 months. OBJECTIVES: To investigate the effectiveness and safety of a hair lotion containing creatine, acetyl tetrapeptide-2 and B vitamins for reducing hair loss in acute telogen effluvium. METHODS: In this open, randomized, controlled study (NCT04652232), women with acute telogen effluvium from two clinical centres were randomly allocated to receive either the lotion and a mild shampoo (intervention group), or the mild shampoo alone (controls). Hair growth parameters and hair loss were measured from phototrichograms at weeks (W) 1, 4, 8 and 16, and through investigator assessments of standardized photographs at W1 and W16. The primary criterion was the change in anagen to telogen (A/T) ratio between W1 and W16. RESULTS: One hundred women (aged 19-50 years) were included (intervention group, N = 51; controls, N = 49). Compared to baseline, the A/T ratio was higher at W16 in both groups and was significantly higher at both W4 and W8 in the intervention group, compared to only at W8 in controls. Significant decreases in telogen hair density were seen at all time points in the intervention group, compared to only at W16 in controls, and the between-group difference was significant at W8 (P = 0.0465). A larger reduction in the total number of hairs shed was observed at W8 in the intervention group (P = 0.0392). Investigator-assessed scores showed improvements in hair density for the intervention group. Global tolerance of the lotion was excellent. CONCLUSIONS: The lotion tested had a significant impact on hair loss in women with acute telogen effluvium and appeared to accelerate recovery from this condition.


Assuntos
Alopecia em Áreas , Fármacos Dermatológicos , Doença Aguda , Alopecia/tratamento farmacológico , Feminino , Cabelo , Humanos , Qualidade de Vida
18.
Molecules ; 26(19)2021 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-34641342

RESUMO

Methylphenidate is a powerful central nervous system stimulant with a high potential for abuse in horse racing. The detection of methylphenidate use is of interest to horse racing authorities for both prior to and during competition. The use of hair as an alternative sampling matrix for equine anti-doping has increased as the number of detectable compounds has expanded. Our laboratory developed a liquid chromatography-high-resolution mass spectrometry method to detect the presence of methylphenidate in submitted samples. Briefly, hair was decontaminated, cut, and pulverized prior to liquid-liquid extraction in basic conditions before introduction to the LC-MS system. Instrumental analysis was conducted using a Thermo Q Exactive mass spectrometer using parallel reaction monitoring using a stepped collision energy to obtain sufficient product ions for qualitative identification. The method was validated and limits of quantitation, linearity, matrix effects, recovery, accuracy, and precision were determined. The method has been applied to confirm the presence of methylphenidate in official samples submitted by racing authorities.


Assuntos
Cabelo/química , Extração Líquido-Líquido/métodos , Metilfenidato/análise , Animais , Cromatografia Líquida , Cavalos , Espectrometria de Massas , Detecção do Abuso de Substâncias/veterinária
19.
20.
Zhonghua Shao Shang Za Zhi ; 37(10): 996-999, 2021 Oct 20.
Artigo em Chinês | MEDLINE | ID: mdl-34689471

RESUMO

Secondary cicatricial alopecia (hereinafter referred to as cicatricial alopecia) after burn and trauma affects the aesthetic appearance and even the physical and mental health of patients, and reduces their quality of life and happiness. Autologous hair transplantation provides an idea for the treatment of cicatricial alopecia, which makes the transplanted hair show a natural growth state. This paper introduces the cicatricial alopecia and autologous hair transplantation and reviews the application and limitations of autologous hair transplantation in treating cicatricial alopecia.


Assuntos
Alopecia , Qualidade de Vida , Alopecia/cirurgia , Cicatriz/patologia , Cicatriz/cirurgia , Cabelo/patologia , Humanos , Transplante de Pele , Transplante Autólogo
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